| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | BAY1125976 perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the BAY1125976_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PKM | pyruvate kinase, muscle | 0.141949 |
| TMSB4X | thymosin beta 4, X-linked | 0.116154 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.11545 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.114197 |
| RPL3 | ribosomal protein L3 | 0.0876473 |
| ZNF608 | zinc finger protein 608 | 0.0825475 |
| ANXA1 | annexin A1 | 0.0814844 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0718155 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0680818 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0679107 |
| EZR | ezrin | 0.0626871 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0625708 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0612677 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0596485 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0551457 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0544376 |
| MKI67 | marker of proliferation Ki-67 | 0.0532808 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0503782 |
| FAT1 | FAT atypical cadherin 1 | 0.0481995 |
| MYO5C | myosin VC | 0.047955 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0441609 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0438771 |
| H1-4 | H1.4 linker histone, cluster member | 0.0418193 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0417033 |
| ENO1 | enolase 1, (alpha) | 0.0411423 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.04111 |
| CENPF | centromere protein F, 350/400kDa | 0.0406877 |
| ANLN | anillin, actin binding protein | 0.0403425 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0373174 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0366697 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0363047 |
| LDHA | lactate dehydrogenase A | 0.0355164 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0348584 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0341012 |
| RPL4 | ribosomal protein L4 | 0.0333528 |
| INTS6 | integrator complex subunit 6 | 0.0330887 |
| ASPH | aspartate beta-hydroxylase | 0.0327398 |
| TPM4 | tropomyosin 4 | 0.0323567 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0319279 |
| PDGFC | platelet derived growth factor C | 0.0314286 |
| RRM2 | ribonucleotide reductase M2 | 0.03134 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0312286 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0312173 |
| FER1L6 | fer-1-like family member 6 | 0.03105 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0300418 |
| FBLN2 | fibulin 2 | 0.0300298 |
| RPS2 | ribosomal protein S2 | 0.0300218 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0296601 |
| CENPE | centromere protein E, 312kDa | 0.0294262 |
| ZNF217 | zinc finger protein 217 | 0.0290051 |
| CCDC88A | coiled-coil domain containing 88A | 0.0288083 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0286326 |
| PRDX2 | peroxiredoxin 2 | 0.0284458 |
| AMOTL2 | angiomotin like 2 | 0.0284305 |
| RPL7 | ribosomal protein L7 | 0.028097 |
| TPM3 | tropomyosin 3 | 0.0279385 |
| BRD2 | bromodomain containing 2 | 0.0279018 |
| VCL | vinculin | 0.0278938 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0277868 |
| RPS15A | ribosomal protein S15a | 0.0276752 |
| B2M | beta-2-microglobulin | 0.0276381 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0275574 |
| PGK1 | phosphoglycerate kinase 1 | 0.0273886 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0272664 |
| PRELID2 | PRELI domain containing 2 | 0.0269285 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0269114 |
| FN1 | fibronectin 1 | 0.0267358 |
| CEP250 | centrosomal protein 250kDa | 0.0262562 |
| HDAC9 | histone deacetylase 9 | 0.0260606 |
| SET | SET nuclear proto-oncogene | 0.0259713 |
| SON | SON DNA binding protein | 0.0250725 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0249327 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0249173 |
| TPI1 | triosephosphate isomerase 1 | 0.0247259 |
| MYOF | myoferlin | 0.0246175 |
| PTMS | parathymosin | 0.024334 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.024325 |
| KLC1 | kinesin light chain 1 | 0.0240654 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0240034 |
| NRDC | nardilysin convertase | 0.0238241 |
| JUN | jun proto-oncogene | 0.0234931 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0234489 |
| PLK2 | polo-like kinase 2 | 0.0233038 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0229636 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0229153 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0227276 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0227054 |
| RPS12 | ribosomal protein S12 | 0.0225904 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain | 0.0225102 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0224601 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0223629 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.022044 |
| HDGF | hepatoma-derived growth factor | 0.0219858 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0219772 |
| EGFR | epidermal growth factor receptor | 0.0218495 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0216808 |
| CEP350 | centrosomal protein 350kDa | 0.0216339 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0214659 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0211885 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0209905 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.213096 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.190575 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.177602 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.151086 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.122575 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.11637 |
| BMP10 | bone morphogenetic protein 10 | -0.113611 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0923043 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0919945 |
| FLNB | filamin B, beta | -0.0919942 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0889174 |
| NBEA | neurobeachin | -0.0873021 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0786211 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0769758 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0693162 |
| EVI5 | ecotropic viral integration site 5 | -0.0668658 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0636238 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0604002 |
| GPHN | gephyrin | -0.0595889 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0591905 |
| NFIA | nuclear factor I/A | -0.055511 |
| RPL35A | ribosomal protein L35a | -0.054285 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0540685 |
| NPAS2 | neuronal PAS domain protein 2 | -0.052962 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0495744 |
| EXOC6B | exocyst complex component 6B | -0.0473641 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.046005 |
| RPLP0 | ribosomal protein, large, P0 | -0.0449305 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.044455 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0442829 |
| NF1 | neurofibromin 1 | -0.0437694 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0430587 |
| TCF12 | transcription factor 12 | -0.0413532 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0413162 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0412429 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0411842 |
| SBF2 | SET binding factor 2 | -0.0406874 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0401461 |
| NEBL | nebulette | -0.0396406 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.039173 |
| GLI3 | GLI family zinc finger 3 | -0.0389491 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0382514 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0378842 |
| MSI2 | musashi RNA-binding protein 2 | -0.0376304 |
| DIAPH2 | diaphanous-related formin 2 | -0.0361339 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0348501 |
| FHIT | fragile histidine triad | -0.0348359 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0345539 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0342228 |
| RBM39 | RNA binding motif protein 39 | -0.0332891 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0329523 |
| PTMA | prothymosin, alpha | -0.0328844 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0328726 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0328206 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0326012 |
| DENND1A | DENN/MADD domain containing 1A | -0.0324107 |
| LIMD1 | LIM domains containing 1 | -0.0319199 |
| RPS21 | ribosomal protein S21 | -0.0317359 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0314315 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0313707 |
| CCND1 | cyclin D1 | -0.0308922 |
| RHBDD1 | rhomboid domain containing 1 | -0.0308829 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0306023 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0305627 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0305494 |
| TRERF1 | transcriptional regulating factor 1 | -0.0304585 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0302197 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0301634 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0297317 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0294626 |
| RPS23 | ribosomal protein S23 | -0.0294318 |
| EHBP1 | EH domain binding protein 1 | -0.0293009 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0287458 |
| RPS24 | ribosomal protein S24 | -0.0286116 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0282143 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0281994 |
| GNAS | GNAS complex locus | -0.0278063 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0276807 |
| RPL34 | ribosomal protein L34 | -0.027506 |
| USP3 | ubiquitin specific peptidase 3 | -0.0274719 |
| CCNI | cyclin I | -0.0273118 |
| RPS13 | ribosomal protein S13 | -0.0270311 |
| HMGA1 | high mobility group AT-hook 1 | -0.0270174 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0269067 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | -0.0268721 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0264102 |
| RTN4 | reticulon 4 | -0.0263757 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0263109 |
| ATP9B | ATPase, class II, type 9B | -0.0261804 |
| TXNRD1 | thioredoxin reductase 1 | -0.0260924 |
| S100A6 | S100 calcium binding protein A6 | -0.0260611 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0257042 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0255918 |
| EXOC4 | exocyst complex component 4 | -0.0252795 |
| RPL11 | ribosomal protein L11 | -0.0252484 |
| AHI1 | Abelson helper integration site 1 | -0.0251662 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0241649 |
| ZNF292 | zinc finger protein 292 | -0.0240147 |
| GOLGA4 | golgin A4 | -0.0236148 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0235292 |
