| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | BAY1125976 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the BAY1125976_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.107085 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0903982 |
| ENO1 | enolase 1, (alpha) | 0.0871632 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0863665 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0839589 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0815872 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.079781 |
| ANGPTL4 | angiopoietin-like 4 | 0.0717962 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.066687 |
| DST | dystonin | 0.06384 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0605853 |
| SVIL | supervillin | 0.0579618 |
| SMAD3 | SMAD family member 3 | 0.0573713 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0542834 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0522066 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0479361 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0478284 |
| ANXA1 | annexin A1 | 0.0449805 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0422927 |
| MSN | moesin | 0.0416757 |
| SET | SET nuclear proto-oncogene | 0.0415399 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0395895 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0372235 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0372223 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0354228 |
| PLEC | plectin | 0.0351831 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0350948 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0334595 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0328027 |
| RPS12 | ribosomal protein S12 | 0.0324819 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0316385 |
| TPI1 | triosephosphate isomerase 1 | 0.030758 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0301732 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0297516 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0294706 |
| TPR | translocated promoter region, nuclear basket protein | 0.028399 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0276324 |
| TJP2 | tight junction protein 2 | 0.027158 |
| RPS3 | ribosomal protein S3 | 0.0267909 |
| TXNIP | thioredoxin interacting protein | 0.0261476 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0254776 |
| PGK1 | phosphoglycerate kinase 1 | 0.0251153 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0250175 |
| RPL3 | ribosomal protein L3 | 0.0248548 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0248456 |
| SIK2 | salt-inducible kinase 2 | 0.0247974 |
| UBQLN1 | ubiquilin 1 | 0.0245705 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0245245 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0244803 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0243791 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0242914 |
| ASPH | aspartate beta-hydroxylase | 0.0242633 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0241134 |
| TXNRD1 | thioredoxin reductase 1 | 0.0240576 |
| RBM25 | RNA binding motif protein 25 | 0.023996 |
| CENPF | centromere protein F, 350/400kDa | 0.0231906 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0230987 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0227483 |
| CENPE | centromere protein E, 312kDa | 0.0227224 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0226798 |
| CANX | calnexin | 0.0225419 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0225146 |
| SQSTM1 | sequestosome 1 | 0.0222085 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0216795 |
| CUL3 | cullin 3 | 0.0216382 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0214233 |
| WHRN | whirlin | 0.0214103 |
| CDK6 | cyclin-dependent kinase 6 | 0.0213995 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0211752 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | 0.0211267 |
| ARRDC3 | arrestin domain containing 3 | 0.0211209 |
| CEP250 | centrosomal protein 250kDa | 0.021095 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0209432 |
| MKI67 | marker of proliferation Ki-67 | 0.0207784 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0206707 |
| SEPTIN2 | septin 2 | 0.0205083 |
| TPM3 | tropomyosin 3 | 0.0204693 |
| GPHN | gephyrin | 0.0204478 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.020445 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.0204096 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0203346 |
| CRY1 | cryptochrome circadian clock 1 | 0.0202716 |
| RPL32 | ribosomal protein L32 | 0.0201507 |
| UBN2 | ubinuclein 2 | 0.0201036 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0200033 |
| AXL | AXL receptor tyrosine kinase | 0.0197738 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.0197159 |
| SUGP2 | SURP and G patch domain containing 2 | 0.019696 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | 0.0195826 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0194936 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0193523 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0192591 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0191782 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0191749 |
| ERGIC3 | ERGIC and golgi 3 | 0.0191729 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0191504 |
| GAN | gigaxonin | 0.0190886 |
| JUN | jun proto-oncogene | 0.0190421 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0190169 |
| SBF2 | SET binding factor 2 | 0.0189979 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.249645 |
| HMGA2 | high mobility group AT-hook 2 | -0.094575 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0777602 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0718784 |
| MT2A | metallothionein 2A | -0.064727 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0610922 |
| IGF2 | insulin-like growth factor 2 | -0.0578171 |
| DNER | delta/notch-like EGF repeat containing | -0.0568996 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0555905 |
| RAB1A | RAB1A, member RAS oncogene family | -0.054026 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0533242 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0503596 |
| EGR1 | early growth response 1 | -0.0487565 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0481638 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0469878 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0463128 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0452462 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0438144 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0436337 |
| OSMR | oncostatin M receptor | -0.0427486 |
| PRR16 | proline rich 16 | -0.0413726 |
| FTL | ferritin, light polypeptide | -0.0408227 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0402969 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0394671 |
| RAD51B | RAD51 paralog B | -0.0392513 |
| NAV2 | neuron navigator 2 | -0.0390206 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0385257 |
| TAOK3 | TAO kinase 3 | -0.0378416 |
| CCNH | cyclin H | -0.0371849 |
| COG5 | component of oligomeric golgi complex 5 | -0.0367846 |
| RPS13 | ribosomal protein S13 | -0.0365139 |
| HM13 | histocompatibility (minor) 13 | -0.0365041 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0364673 |
| PCNX2 | pecanex 2 | -0.035615 |
| RPS29 | ribosomal protein S29 | -0.0353666 |
| FBXO11 | F-box protein 11 | -0.0352707 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0351364 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0348805 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0336566 |
| PDE8A | phosphodiesterase 8A | -0.0333087 |
| MCL1 | myeloid cell leukemia 1 | -0.0328255 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0323882 |
| PODXL | podocalyxin-like | -0.0323623 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0322292 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0312735 |
| SMYD3 | SET and MYND domain containing 3 | -0.0308912 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0308113 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0306394 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0305587 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0304181 |
| CD44 | CD44 molecule (Indian blood group) | -0.0302217 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0297572 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0297414 |
| ATG7 | autophagy related 7 | -0.029391 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0293711 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0291483 |
| ZBTB1 | zinc finger and BTB domain containing 1 | -0.0288888 |
| MTDH | metadherin | -0.028464 |
| FUS | FUS RNA binding protein | -0.0277923 |
| PCNX4 | pecanex 4 | -0.0277693 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0276511 |
| BBX | bobby sox homolog (Drosophila) | -0.0274454 |
| EGFR | epidermal growth factor receptor | -0.0274071 |
| FAM13B | family with sequence similarity 13, member B | -0.0274015 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0271029 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0270587 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0270086 |
| VCL | vinculin | -0.0269196 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0268349 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0268169 |
| CCDC138 | coiled-coil domain containing 138 | -0.0267637 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0266607 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0263566 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0263239 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0261515 |
| MMP1 | matrix metallopeptidase 1 | -0.0260898 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0257196 |
| FERMT2 | fermitin family member 2 | -0.0256424 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0255972 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0255555 |
| FNBP1L | formin binding protein 1-like | -0.0250937 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0250514 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0248169 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.024517 |
| RPL15 | ribosomal protein L15 | -0.0244739 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0244708 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0240916 |
| FMNL2 | formin-like 2 | -0.0240633 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0238885 |
| BRD4 | bromodomain containing 4 | -0.0237906 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0237863 |
| POTEF | POTE ankyrin domain family, member F | -0.0236991 |
| ATM | ATM serine/threonine kinase | -0.0236576 |
| RPL12 | ribosomal protein L12 | -0.0235776 |
| FMN1 | formin 1 | -0.023515 |
| MYO9B | myosin IXB | -0.0233727 |
| MIS18BP1 | MIS18 binding protein 1 | -0.023301 |
| TMSB10 | thymosin beta 10 | -0.0231633 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0231612 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0231254 |
