| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | BAY1125976 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the BAY1125976_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.154794 |
| ASPH | aspartate beta-hydroxylase | 0.105988 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.104903 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0926878 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0923224 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0894246 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0885968 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0739913 |
| ENO1 | enolase 1, (alpha) | 0.0721549 |
| VIM | vimentin | 0.0692345 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0686771 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0659337 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0648769 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0561251 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0545761 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0512013 |
| MT2A | metallothionein 2A | 0.050995 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0498299 |
| SFTPA2 | surfactant protein A2 | 0.0493345 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0473372 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0471184 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0468346 |
| TPI1 | triosephosphate isomerase 1 | 0.0463766 |
| SVIL | supervillin | 0.0426978 |
| TMSB4X | thymosin beta 4, X-linked | 0.0424209 |
| AHNAK | AHNAK nucleoprotein | 0.0412057 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0411155 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0401995 |
| PLEC | plectin | 0.0394034 |
| SQSTM1 | sequestosome 1 | 0.0393158 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0387485 |
| FAT1 | FAT atypical cadherin 1 | 0.0376626 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0376403 |
| ATF6 | activating transcription factor 6 | 0.0370333 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0361995 |
| SMAD3 | SMAD family member 3 | 0.0357974 |
| ANGPTL4 | angiopoietin-like 4 | 0.0345063 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.034153 |
| PLIN2 | perilipin 2 | 0.0337833 |
| CALR | calreticulin | 0.0332893 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0332485 |
| TPM3 | tropomyosin 3 | 0.0331514 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.032986 |
| FAM107B | family with sequence similarity 107, member B | 0.0324877 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0322995 |
| RPL26 | ribosomal protein L26 | 0.0320061 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.031877 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.031223 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0311639 |
| DUSP6 | dual specificity phosphatase 6 | 0.0309569 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0300445 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0294153 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0270762 |
| EZR | ezrin | 0.0267699 |
| RPS27 | ribosomal protein S27 | 0.0267436 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0266893 |
| PRRC2C | proline-rich coiled-coil 2C | 0.026346 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0262618 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0261771 |
| RPL37A | ribosomal protein L37a | 0.0259618 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0251716 |
| RPS8 | ribosomal protein S8 | 0.0251481 |
| EMP1 | epithelial membrane protein 1 | 0.0250277 |
| EREG | epiregulin | 0.0249452 |
| LMO7 | LIM domain 7 | 0.0247642 |
| APP | amyloid beta (A4) precursor protein | 0.0247638 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0245718 |
| ATF3 | activating transcription factor 3 | 0.0245426 |
| CRY1 | cryptochrome circadian clock 1 | 0.02446 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0242809 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0242074 |
| RPS12 | ribosomal protein S12 | 0.0241275 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0241214 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0239033 |
| HYOU1 | hypoxia up-regulated 1 | 0.0238874 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.023853 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0238296 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0237377 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0235122 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.023508 |
| SGMS2 | sphingomyelin synthase 2 | 0.0234911 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0230574 |
| CANX | calnexin | 0.0229611 |
| RPL3 | ribosomal protein L3 | 0.0229137 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0228739 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0227393 |
| EGFR | epidermal growth factor receptor | 0.0224993 |
| MYOF | myoferlin | 0.0223371 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.02205 |
| SEPTIN9 | septin 9 | 0.0219682 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.021893 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0218329 |
| CEP350 | centrosomal protein 350kDa | 0.0217937 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0212318 |
| RPL23 | ribosomal protein L23 | 0.0211721 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.021097 |
| RACK1 | receptor for activated C kinase 1 | 0.0209672 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0208301 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0207731 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0207727 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.238455 |
| NRG1 | neuregulin 1 | -0.211873 |
| HMGA2 | high mobility group AT-hook 2 | -0.12119 |
| NDRG1 | N-myc downstream regulated 1 | -0.0975673 |
| FN1 | fibronectin 1 | -0.096656 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0964386 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0950627 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0912608 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0694791 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0581292 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0580988 |
| GLIS3 | GLIS family zinc finger 3 | -0.0498055 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0481702 |
| VEGFA | vascular endothelial growth factor A | -0.045106 |
| POTEF | POTE ankyrin domain family, member F | -0.0447454 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0444205 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0420047 |
| NRP1 | neuropilin 1 | -0.0390427 |
| EGR1 | early growth response 1 | -0.0380685 |
| SYT1 | synaptotagmin I | -0.0369139 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0349713 |
| TMEM165 | transmembrane protein 165 | -0.0347311 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.033572 |
| CCNL1 | cyclin L1 | -0.033461 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0312199 |
| RUNX2 | runt-related transcription factor 2 | -0.0308116 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0305397 |
| ITGA1 | integrin, alpha 1 | -0.0297876 |
| FOSL1 | FOS-like antigen 1 | -0.029398 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0286697 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0279868 |
| ATN1 | atrophin 1 | -0.0271962 |
| OSMR | oncostatin M receptor | -0.0269324 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0266414 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0265891 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0263733 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0262813 |
| PFN1 | profilin 1 | -0.0257126 |
| HMGA1 | high mobility group AT-hook 1 | -0.0250644 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0248051 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0246787 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0243113 |
| AEBP2 | AE binding protein 2 | -0.0241663 |
| RBM39 | RNA binding motif protein 39 | -0.0238345 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0237664 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0236171 |
| TENM4 | teneurin transmembrane protein 4 | -0.0234902 |
| RTN4 | reticulon 4 | -0.0232328 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0231629 |
| UBXN4 | UBX domain protein 4 | -0.0231587 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.0231271 |
| FAM20C | family with sequence similarity 20, member C | -0.0226963 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0224769 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0222039 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0221231 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0218766 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0218318 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0216632 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0215887 |
| ZNF292 | zinc finger protein 292 | -0.0214097 |
| ARF4 | ADP-ribosylation factor 4 | -0.0210901 |
| WDR45B | WD repeat domain 45B | -0.021007 |
| CTSD | cathepsin D | -0.0208858 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0206707 |
| BSG | basigin (Ok blood group) | -0.0205524 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0203938 |
| TNS3 | tensin 3 | -0.0203694 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0199281 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0196831 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0195939 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0195832 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0195476 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0192888 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0190428 |
| GNAS | GNAS complex locus | -0.0190179 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0188145 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0187185 |
| NUP58 | nucleoporin 58 | -0.0187096 |
| RBM47 | RNA binding motif protein 47 | -0.0186538 |
| ETV6 | ets variant 6 | -0.0185466 |
| RNF145 | ring finger protein 145 | -0.0185298 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0184942 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0184844 |
| PCBP2 | poly(rC) binding protein 2 | -0.0183669 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0182442 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0182225 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0180685 |
| PCNX4 | pecanex 4 | -0.0179402 |
| RANBP17 | RAN binding protein 17 | -0.0178637 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.017765 |
| TGFA | transforming growth factor, alpha | -0.017615 |
| USP12 | ubiquitin specific peptidase 12 | -0.0172151 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0171248 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0169849 |
| DENND5B | DENN/MADD domain containing 5B | -0.0169612 |
| FRY | furry homolog (Drosophila) | -0.0167549 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0166631 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0166168 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0165795 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.01633 |
