BCB000038-7547 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the BCB000038-7547 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADAM17 ADAM metallopeptidase domain 17
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ANP32A-IT1 ANP32A intronic transcript 1
ARHGAP28 Rho GTPase activating protein 28
ARMC4 armadillo repeat containing 4
ARTN artemin
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BTF3P12 basic transcription factor 3 pseudogene 12
C10ORF10 chromosome 10 open reading frame 10
C11ORF30 chromosome 11 open reading frame 30
C9ORF116 chromosome 9 open reading frame 116
CHM choroideremia (Rab escort protein 1)
COL2A1 collagen, type II, alpha 1
COL6A1 collagen, type VI, alpha 1
CRY2 cryptochrome circadian clock 2
CTH cystathionine gamma-lyase
CTSF cathepsin F
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DAPK3 death-associated protein kinase 3
EIF5A2 eukaryotic translation initiation factor 5A2
EYA4 EYA transcriptional coactivator and phosphatase 4
FBXO31 F-box protein 31
FN1 fibronectin 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GAREM GRB2 associated, regulator of MAPK1
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR107 G protein-coupled receptor 107
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GREB1L growth regulation by estrogen in breast cancer-like
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HHAT hedgehog acyltransferase
HN1L hematological and neurological expressed 1-like
HPS4 Hermansky-Pudlak syndrome 4
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KLF12 Kruppel-like factor 12
LIG4 ligase IV, DNA, ATP-dependent
LINC00094 long intergenic non-protein coding RNA 94
LOC81691 exonuclease NEF-sp
LRRC23 leucine rich repeat containing 23
LYRM9 LYR motif containing 9
LZTR1 leucine-zipper-like transcription regulator 1
MINK1 misshapen-like kinase 1
MPDZ multiple PDZ domain protein
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTERF4 mitochondrial transcription termination factor 4
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NF1 neurofibromin 1
NPM3 nucleophosmin/nucleoplasmin 3
NUP205 nucleoporin 205kDa
OSBPL10 oxysterol binding protein-like 10
PANK3 pantothenate kinase 3
PARP3 poly (ADP-ribose) polymerase family, member 3
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PLAC8 placenta-specific 8
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTGES prostaglandin E synthase
RBBP9 retinoblastoma binding protein 9
REEP2 receptor accessory protein 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN1B sodium channel, voltage gated, type I beta subunit
SERBP1 SERPINE1 mRNA binding protein 1
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SMG5 SMG5 nonsense mediated mRNA decay factor
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNX13 sorting nexin 13
SPHK2 sphingosine kinase 2
SRCAP Snf2-related CREBBP activator protein
SRPK2 SRSF protein kinase 2
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
STC1 stanniocalcin 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAGLN transgelin
TAOK2 TAO kinase 2
TNRC6B trinucleotide repeat containing 6B
TOM1 target of myb1 (chicken)
TP53I11 tumor protein p53 inducible protein 11
TRIO trio Rho guanine nucleotide exchange factor
TWF1 twinfilin actin binding protein 1
WDR4 WD repeat domain 4
ZER1 zyg-11 related, cell cycle regulator
ZNF609 zinc finger protein 609
ZNF671 zinc finger protein 671

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAP2 ArfGAP with dual PH domains 2
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAG4 BCL2-associated athanogene 4
BMP4 bone morphogenetic protein 4
C20ORF195 chromosome 20 open reading frame 195
C7ORF43 chromosome 7 open reading frame 43
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCL22 chemokine (C-C motif) ligand 22
CDK3 cyclin-dependent kinase 3
CLDN15 claudin 15
CLEC3B C-type lectin domain family 3, member B
CLTCL1 clathrin, heavy chain-like 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNTLN centlein, centrosomal protein
CORT cortistatin
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDN dendrin
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GAS2 growth arrest-specific 2
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GPX2 glutathione peroxidase 2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H3I histone cluster 1, H3i
HOXA6 homeobox A6
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IFI44L interferon-induced protein 44-like
IFNA14 interferon, alpha 14
IGSF3 immunoglobulin superfamily, member 3
IL12RB2 interleukin 12 receptor, beta 2
ITGA10 integrin, alpha 10
KCNK10 potassium channel, two pore domain subfamily K, member 10
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
LAX1 lymphocyte transmembrane adaptor 1
LOC100294391 uncharacterized LOC100294391
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MNX1 motor neuron and pancreas homeobox 1
MUC3B mucin 3B, cell surface associated
MX1 MX dynamin-like GTPase 1
NCS1 neuronal calcium sensor 1
NEK11 NIMA-related kinase 11
NT5C 5', 3'-nucleotidase, cytosolic
OLFML2A olfactomedin-like 2A
OSGIN1 oxidative stress induced growth inhibitor 1
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PCOLCE procollagen C-endopeptidase enhancer
PDE12 phosphodiesterase 12
PDZK1 PDZ domain containing 1
PHF14 PHD finger protein 14
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PODXL2 podocalyxin-like 2
POM121 POM121 transmembrane nucleoporin
PPT2 palmitoyl-protein thioesterase 2
PRKCE protein kinase C, epsilon
PTK6 protein tyrosine kinase 6
PTPRH protein tyrosine phosphatase, receptor type, H
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS17 regulator of G-protein signaling 17
RHOBTB2 Rho-related BTB domain containing 2
RNF2 ring finger protein 2
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RUNDC3B RUN domain containing 3B
SEC14L2 SEC14-like 2 (S. cerevisiae)
SERTAD3 SERTA domain containing 3
SH3GL2 SH3-domain GRB2-like 2
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAC SH3 and cysteine rich domain
SULT4A1 sulfotransferase family 4A, member 1
TCTN2 tectonic family member 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM180 transmembrane protein 180
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TSC22D4 TSC22 domain family, member 4
UGT8 UDP glycosyltransferase 8
URM1 ubiquitin related modifier 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XYLT2 xylosyltransferase II
YPEL1 yippee-like 1 (Drosophila)
ZFP30 ZFP30 zinc finger protein
ZNF197 zinc finger protein 197
ZNF205 zinc finger protein 205
ZNF510 zinc finger protein 510
ZNF580 zinc finger protein 580
ZNF667 zinc finger protein 667
ZNF711 zinc finger protein 711
ZNF74 zinc finger protein 74