BCB000039-7536 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the BCB000039-7536 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ACVR1B activin A receptor, type IB
ADAM12 ADAM metallopeptidase domain 12
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGAP28 Rho GTPase activating protein 28
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ART1 ADP-ribosyltransferase 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAX BCL2-associated X protein
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL9 B-cell CLL/lymphoma 9
CCDC186 coiled-coil domain containing 186
CCDC64 coiled-coil domain containing 64
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CEMIP cell migration inducing protein, hyaluronan binding
CLDN8 claudin 8
CLIC3 chloride intracellular channel 3
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CPM carboxypeptidase M
CPT1A carnitine palmitoyltransferase 1A (liver)
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAL4 dynein, axonemal, light chain 4
ECE1 endothelin converting enzyme 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELOVL4 ELOVL fatty acid elongase 4
EPHB2 EPH receptor B2
ERN2 endoplasmic reticulum to nucleus signaling 2
EYA4 EYA transcriptional coactivator and phosphatase 4
F3 coagulation factor III (thromboplastin, tissue factor)
FAM105A family with sequence similarity 105, member A
FAM155A family with sequence similarity 155, member A
FAM69A family with sequence similarity 69, member A
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAS8 growth arrest-specific 8
GRAMD4 GRAM domain containing 4
GSK3A glycogen synthase kinase 3 alpha
HCFC1 host cell factor C1
HEATR6 HEAT repeat containing 6
HYI hydroxypyruvate isomerase (putative)
IL1B interleukin 1, beta
KIAA0319L KIAA0319-like
KIAA1467 KIAA1467
KLF4 Kruppel-like factor 4 (gut)
LIMK2 LIM domain kinase 2
MED1 mediator complex subunit 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MNX1 motor neuron and pancreas homeobox 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NUP62CL nucleoporin 62kDa C-terminal like
OGFR opioid growth factor receptor
PASK PAS domain containing serine/threonine kinase
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDH1 protocadherin 1
PDGFA platelet-derived growth factor alpha polypeptide
PLAA phospholipase A2-activating protein
PNPLA4 patatin-like phospholipase domain containing 4
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRDM2 PR domain containing 2, with ZNF domain
PRR15L proline rich 15-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNF146 ring finger protein 146
RUNX1 runt-related transcription factor 1
SCAPER S-phase cyclin A-associated protein in the ER
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SETDB1 SET domain, bifurcated 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SMAD3 SMAD family member 3
SOX4 SRY (sex determining region Y)-box 4
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STARD5 StAR-related lipid transfer (START) domain containing 5
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCF12 transcription factor 12
TET3 tet methylcytosine dioxygenase 3
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNS1 tensin 1
TRIO trio Rho guanine nucleotide exchange factor
TTBK2 tau tubulin kinase 2
TTC39A tetratricopeptide repeat domain 39A
WWOX WW domain containing oxidoreductase
YTHDC2 YTH domain containing 2
ZBTB3 zinc finger and BTB domain containing 3
ZFP36L2 ZFP36 ring finger protein-like 2
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF202 zinc finger protein 202

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ACVR2B activin A receptor, type IIB
AFAP1 actin filament associated protein 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BICD1 bicaudal D homolog 1 (Drosophila)
BTBD18 BTB (POZ) domain containing 18
C22ORF29 chromosome 22 open reading frame 29
C8ORF44 chromosome 8 open reading frame 44
CBX8 chromobox homolog 8
CD82 CD82 molecule
CDON cell adhesion associated, oncogene regulated
CENPO centromere protein O
CEP131 centrosomal protein 131kDa
CES3 carboxylesterase 3
CLCN5 chloride channel, voltage-sensitive 5
CLCN6 chloride channel, voltage-sensitive 6
CLDN9 claudin 9
COBL cordon-bleu WH2 repeat protein
CORO1A coronin, actin binding protein, 1A
CRYGC crystallin, gamma C
DCAF17 DDB1 and CUL4 associated factor 17
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLK2 delta-like 2 homolog (Drosophila)
DNAH7 dynein, axonemal, heavy chain 7
E4F1 E4F transcription factor 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC8 excision repair cross-complementation group 8
ETV6 ets variant 6
EXD3 exonuclease 3'-5' domain containing 3
FBXL15 F-box and leucine-rich repeat protein 15
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FLCN folliculin
FRMD8 FERM domain containing 8
GLB1L galactosidase, beta 1-like
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSTCD glutathione S-transferase, C-terminal domain containing
HDAC11 histone deacetylase 11
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H3G histone cluster 1, H3g
HLX H2.0-like homeobox
HOXB9 homeobox B9
HOXC4 homeobox C4
HPSE heparanase
HSF2BP heat shock transcription factor 2 binding protein
LIG4 ligase IV, DNA, ATP-dependent
LPAR3 lysophosphatidic acid receptor 3
MFGE8 milk fat globule-EGF factor 8 protein
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
NINJ1 ninjurin 1
NME5 NME/NM23 family member 5
NRTN neurturin
NT5M 5',3'-nucleotidase, mitochondrial
OLFML2B olfactomedin-like 2B
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDGFRL platelet-derived growth factor receptor-like
PLAC1 placenta-specific 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLR1E polymerase (RNA) I polypeptide E, 53kDa
PRMT7 protein arginine methyltransferase 7
RAB33B RAB33B, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RUSC2 RUN and SH3 domain containing 2
S100A3 S100 calcium binding protein A3
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SETD6 SET domain containing 6
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC46A3 solute carrier family 46, member 3
SNRPN small nuclear ribonucleoprotein polypeptide N
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM159 transmembrane protein 159
TMEM209 transmembrane protein 209
TRABD TraB domain containing
TRIM21 tripartite motif containing 21
TRIM25 tripartite motif containing 25
TUBG2 tubulin, gamma 2
URGCP upregulator of cell proliferation
USP18 ubiquitin specific peptidase 18
USP6 ubiquitin specific peptidase 6
XYLT2 xylosyltransferase II
ZFP30 ZFP30 zinc finger protein
ZFP36 ZFP36 ring finger protein
ZNF197 zinc finger protein 197
ZNF205 zinc finger protein 205
ZNF32 zinc finger protein 32
ZNF428 zinc finger protein 428
ZNF574 zinc finger protein 574
ZNF667 zinc finger protein 667