BCHE Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description butyrylcholinesterase|Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 590)
External Link https://ncbi.nlm.nih.gov/gene/590
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Genes

499 genes differentially expressed following the BCHE gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.0159538
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.0142006
FASN fatty acid synthase 0.0139042
TPSAB1 tryptase alpha/beta 1 0.0137098
PROM1 prominin 1 0.0135464
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0130507
VTCN1 V-set domain containing T cell activation inhibitor 1 0.0129395
TSPAN12 tetraspanin 12 0.0129274
NOTCH1 notch 1 0.0128538
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.0127068
RTN3 reticulon 3 0.0124897
GAS1 growth arrest-specific 1 0.0124444
PTK2B protein tyrosine kinase 2 beta 0.0122041
DGKZ diacylglycerol kinase, zeta 0.0120189
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.011844
RTN2 reticulon 2 0.0118004
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.0116665
CCND1 cyclin D1 0.0116191
KAZN kazrin, periplakin interacting protein 0.0114234
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.0111583
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.0110976
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.0110293
IRX5 iroquois homeobox 5 0.0107491
EML3 echinoderm microtubule associated protein like 3 0.0107136
EFNB2 ephrin-B2 0.0106562
CDC20 cell division cycle 20 0.0105522
NPM3 nucleophosmin/nucleoplasmin 3 0.0104674
TNNT1 troponin T type 1 (skeletal, slow) 0.0104315
PDPK1 3-phosphoinositide dependent protein kinase 1 0.0104269
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 0.0104249
INSIG1 insulin induced gene 1 0.0103866
RAPSN receptor-associated protein of the synapse 0.0102484
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.0102375
CRABP2 cellular retinoic acid binding protein 2 0.0102371
ADAM9 ADAM metallopeptidase domain 9 0.0101839
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.010109
KRAS Kirsten rat sarcoma viral oncogene homolog 0.0100167
PHACTR2 phosphatase and actin regulator 2 0.010015
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00991214
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00988922
DEFA4 defensin, alpha 4, corticostatin 0.00988692
AZU1 azurocidin 1 0.00983717
PRRC2A proline-rich coiled-coil 2A 0.00978764
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00978028
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00976752
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00975509
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.00974534
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.00973185
COMP cartilage oligomeric matrix protein 0.00972202
TEX30 testis expressed 30 0.00968384
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.00966388
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 0.0096627
ISYNA1 inositol-3-phosphate synthase 1 0.00964225
LMNB2 lamin B2 0.00962388
SLIT2 slit homolog 2 (Drosophila) 0.00960774
MACROD1 MACRO domain containing 1 0.00955957
PILRB paired immunoglobin-like type 2 receptor beta 0.00947791
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 0.00946336
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.00946021
TECR trans-2,3-enoyl-CoA reductase 0.00945497
BMP4 bone morphogenetic protein 4 0.00944723
MEIS2 Meis homeobox 2 0.00939763
SLC38A1 solute carrier family 38, member 1 0.00939539
CAMP cathelicidin antimicrobial peptide 0.00939537
DCXR dicarbonyl/L-xylulose reductase 0.00939496
EMP3 epithelial membrane protein 3 0.00933609
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.0093131
FAM3C family with sequence similarity 3, member C 0.0093061
CRISP3 cysteine-rich secretory protein 3 0.00929206
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.00928283
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 0.00919583
PCP4 Purkinje cell protein 4 0.00919418
TUBGCP3 tubulin, gamma complex associated protein 3 0.00917414
METTL7A methyltransferase like 7A 0.0091592
TK1 thymidine kinase 1, soluble 0.00915733
ARMCX1 armadillo repeat containing, X-linked 1 0.00908347
TARDBP TAR DNA binding protein 0.00907003
CENPT centromere protein T 0.00904067
LYN LYN proto-oncogene, Src family tyrosine kinase 0.00904047
STK25 serine/threonine kinase 25 0.00900916
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.00898691
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 0.00898382
NELFB negative elongation factor complex member B 0.00897921
SFRP4 secreted frizzled-related protein 4 0.00896532
FST follistatin 0.00893851
CLDN3 claudin 3 0.0088745
CCDC92 coiled-coil domain containing 92 0.00882688
RPA3 replication protein A3, 14kDa 0.00881638
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.00881112
IPO9 importin 9 0.00881012
CRYM crystallin, mu 0.00880859
LTBP2 latent transforming growth factor beta binding protein 2 0.00880751
SMAD7 SMAD family member 7 0.0087926
WASL Wiskott-Aldrich syndrome-like 0.00871402
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.0087088
GUCY1B3 guanylate cyclase 1, soluble, beta 3 0.00869886
NPR3 natriuretic peptide receptor 3 0.00863941
GSTM3 glutathione S-transferase mu 3 (brain) 0.00863846
MFSD10 major facilitator superfamily domain containing 10 0.00857905
THOC6 THO complex 6 0.00856093
EFHD1 EF-hand domain family, member D1 0.00855672
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00855303
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00854077
ELANE elastase, neutrophil expressed 0.00852652
CRIP2 cysteine-rich protein 2 0.00851897
MT1E metallothionein 1E 0.00847688
CLC Charcot-Leyden crystal galectin 0.00847224
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00842821
LEPR leptin receptor 0.00840851
ZBTB18 zinc finger and BTB domain containing 18 0.00840587
S100A9 S100 calcium binding protein A9 0.00840328
GATA2 GATA binding protein 2 0.00838586
ZBTB7A zinc finger and BTB domain containing 7A 0.00838231
HMGB3 high mobility group box 3 0.00836244
CLEC3B C-type lectin domain family 3, member B 0.00836135
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 0.00835109
SMTN smoothelin 0.00833542
ASRGL1 asparaginase like 1 0.00832216
PTMS parathymosin 0.0083207
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 0.0082998
IGFBP5 insulin-like growth factor binding protein 5 0.00827391
NRGN neurogranin (protein kinase C substrate, RC3) 0.00827098
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.00825425
KIAA0100 KIAA0100 0.00824303
DPP4 dipeptidyl-peptidase 4 0.00823716
DCAF15 DDB1 and CUL4 associated factor 15 0.00823617
SPIN1 spindlin 1 0.00815788
BTBD2 BTB (POZ) domain containing 2 0.00811518
CUEDC1 CUE domain containing 1 0.00810373
PSRC1 proline/serine-rich coiled-coil 1 0.00810289
ADGRF5 adhesion G protein-coupled receptor F5 0.00809946
ELN elastin 0.00805434
ADCY9 adenylate cyclase 9 0.00802983
THAP12 THAP domain containing 12 0.00802331
SIX1 SIX homeobox 1 0.00801111
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.00799796
GPSM2 G-protein signaling modulator 2 0.00798823
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.00798546
TYMS thymidylate synthetase 0.00798273
SCAF4 SR-related CTD-associated factor 4 0.00796964
WSB1 WD repeat and SOCS box containing 1 0.00796169
CCND2 cyclin D2 0.00791305
NADK NAD kinase 0.00791292
DBF4 DBF4 zinc finger 0.00790721
DACH1 dachshund family transcription factor 1 0.00790456
ANAPC2 anaphase promoting complex subunit 2 0.00787226
HOXC10 homeobox C10 0.00786954
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.007859
HAUS3 HAUS augmin-like complex, subunit 3 0.00785877
SGSM2 small G protein signaling modulator 2 0.00783575
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.00782713
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit 0.00782185
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 0.00781372
NINJ2 ninjurin 2 0.00778695
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.00777917
MRPL12 mitochondrial ribosomal protein L12 0.00776644
MCM7 minichromosome maintenance complex component 7 0.00775014
XYLT1 xylosyltransferase I 0.00774176
CREB1 cAMP responsive element binding protein 1 0.00773791
H2AZ1 H2A.Z variant histone 1 0.00773686
GRAMD4 GRAM domain containing 4 0.00773561
SIX2 SIX homeobox 2 0.00770316
SHB Src homology 2 domain containing adaptor protein B 0.00768666
TGFB1 transforming growth factor, beta 1 0.00768486
RCAN2 regulator of calcineurin 2 0.00768478
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 0.00767092
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.00766412
CTNND1 catenin (cadherin-associated protein), delta 1 0.00765639
RXRA retinoid X receptor, alpha 0.0076505
TIMP3 TIMP metallopeptidase inhibitor 3 0.0076437
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.00764245
S100A8 S100 calcium binding protein A8 0.00763892
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.00762783
SMYD3 SET and MYND domain containing 3 0.00762732
ARID1A AT rich interactive domain 1A (SWI-like) 0.00762622
DPYD dihydropyrimidine dehydrogenase 0.00761153
LRRC17 leucine rich repeat containing 17 0.00759541
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00758292
CCNL2 cyclin L2 0.00756638
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00754476
EREG epiregulin 0.00753774
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 0.00753515
CXCL14 chemokine (C-X-C motif) ligand 14 0.00752748
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 0.00751429
NBPF10 neuroblastoma breakpoint family, member 10 0.00750571
APOD apolipoprotein D 0.00749442
LBR lamin B receptor 0.00749402
CXCL9 chemokine (C-X-C motif) ligand 9 0.00748744
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.00748344
H1-0 H1.0 linker histone 0.00746482
AURKB aurora kinase B 0.00744517
TOB1 transducer of ERBB2, 1 0.00744152
UGCG UDP-glucose ceramide glucosyltransferase 0.00743818
ANGPTL2 angiopoietin-like 2 0.00743586
TTC38 tetratricopeptide repeat domain 38 0.00743022
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.00741719
DPYSL2 dihydropyrimidinase-like 2 0.00741708
RECQL4 RecQ protein-like 4 0.00739373
ABHD17A abhydrolase domain containing 17A 0.00738973
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.00738677
ZNF91 zinc finger protein 91 0.00738223
G0S2 G0/G1 switch 2 0.00737196
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00737013
KIAA1109 KIAA1109 0.00736555
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00736549
ZBTB20 zinc finger and BTB domain containing 20 0.00736364
JAG2 jagged 2 0.00736078
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.00735882
PIMREG PICALM interacting mitotic regulator 0.00734558
PNPLA6 patatin-like phospholipase domain containing 6 0.00731037
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00728713
SIKE1 suppressor of IKBKE 1 0.00728194
CAPN1 calpain 1, (mu/I) large subunit 0.0072793
DPT dermatopontin 0.00727886
NOTCH2 notch 2 0.00726719
EHD2 EH-domain containing 2 0.00726576
ELAC2 elaC ribonuclease Z 2 0.00725929
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00725863
EFHC2 EF-hand domain (C-terminal) containing 2 0.0072468
INTS1 integrator complex subunit 1 0.00723768
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.00723568
SSBP2 single-stranded DNA binding protein 2 0.00722074
PDLIM7 PDZ and LIM domain 7 (enigma) 0.00721282
SCRIB scribbled planar cell polarity protein 0.0072043
GHR growth hormone receptor 0.00720317
RPA1 replication protein A1, 70kDa 0.00719103
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.00718848
IDO1 indoleamine 2,3-dioxygenase 1 0.00718535
CCL8 chemokine (C-C motif) ligand 8 0.00718064
WDR18 WD repeat domain 18 0.00717982
SCGB1D2 secretoglobin, family 1D, member 2 0.00717843
CLUH clustered mitochondria (cluA/CLU1) homolog 0.00715579
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.00715422
ZWINT ZW10 interacting kinetochore protein 0.00715325
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00714872
TSPAN5 tetraspanin 5 0.00713032
ENG endoglin 0.00711248
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.00711229
ESR1 estrogen receptor 1 0.00710804
RPIA ribose 5-phosphate isomerase A 0.00710749
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.00710135
GEMIN4 gem (nuclear organelle) associated protein 4 0.00707809
CERK ceramide kinase 0.00707201
PMPCA peptidase (mitochondrial processing) alpha 0.0070714
CD320 CD320 molecule 0.00704995
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.0070438
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 0.00704118
GATAD2A GATA zinc finger domain containing 2A 0.00703922
RBBP8 retinoblastoma binding protein 8 0.00703162

decreased expression

Symbol Name Standardized Value
IFI27 interferon, alpha-inducible protein 27 -0.019292
ATF3 activating transcription factor 3 -0.018683
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0182318
HSPA1A heat shock 70kDa protein 1A -0.01778
S100A10 S100 calcium binding protein A10 -0.0170753
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.0167801
MX1 MX dynamin-like GTPase 1 -0.0164504
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0163722
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0158644
IFI16 interferon, gamma-inducible protein 16 -0.0155956
TSPAN8 tetraspanin 8 -0.0152944
ISG20 interferon stimulated exonuclease gene 20kDa -0.0151068
LAMP3 lysosomal-associated membrane protein 3 -0.0146535
KRT13 keratin 13, type I -0.0142399
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.0141583
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.0139579
CXCL5 chemokine (C-X-C motif) ligand 5 -0.0136116
TM4SF1 transmembrane 4 L six family member 1 -0.0135868
C1S complement component 1, s subcomponent -0.0135826
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0134447
ANXA1 annexin A1 -0.0133702
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.0131717
MYO1C myosin IC -0.0127995
CXADR coxsackie virus and adenovirus receptor -0.0127561
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.012744
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.0127148
TSC22D1 TSC22 domain family, member 1 -0.0126642
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -0.0126622
FOSL2 FOS-like antigen 2 -0.0126546
ISG15 ISG15 ubiquitin-like modifier -0.0125802
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.0125374
MVP major vault protein -0.0124579
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.0123027
SPRR3 small proline-rich protein 3 -0.0122619
EGR2 early growth response 2 -0.0122315
GDI2 GDP dissociation inhibitor 2 -0.0122282
KYNU kynureninase -0.0122125
LUM lumican -0.0119571
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0119226
C3 complement component 3 -0.0119048
PLP1 proteolipid protein 1 -0.0118526
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.011709
LAMC2 laminin, gamma 2 -0.0116373
TUBB2B tubulin, beta 2B class IIb -0.0115201
RBKS ribokinase -0.0114276
HSPB1 heat shock 27kDa protein 1 -0.0113777
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.0113571
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.0113363
PRAME preferentially expressed antigen in melanoma -0.0112776
HSPH1 heat shock 105kDa/110kDa protein 1 -0.0112344
AQP3 aquaporin 3 (Gill blood group) -0.0111993
SELL selectin L -0.0111472
SCEL sciellin -0.0110111
BHLHE41 basic helix-loop-helix family, member e41 -0.0109973
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0108914
IRS2 insulin receptor substrate 2 -0.0108816
TAGLN2 transgelin 2 -0.0108257
NEBL nebulette -0.0107632
ABHD4 abhydrolase domain containing 4 -0.0107205
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0106506
MCL1 myeloid cell leukemia 1 -0.0106447
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0106327
CXCL2 chemokine (C-X-C motif) ligand 2 -0.0106266
KRT17 keratin 17, type I -0.0105985
RETREG1 reticulophagy regulator 1 -0.0105951
CEMIP cell migration inducing protein, hyaluronan binding -0.0105202
LXN latexin -0.0105041
CSRP2 cysteine and glycine-rich protein 2 -0.0104883
PSAP prosaposin -0.0104867
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0104191
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.0104186
DCHS1 dachsous cadherin-related 1 -0.0103395
EIF5 eukaryotic translation initiation factor 5 -0.0103328
IFI44L interferon-induced protein 44-like -0.0103169
LBH limb bud and heart development -0.0103042
C8ORF4 chromosome 8 open reading frame 4 -0.0102831
IL32 interleukin 32 -0.0102661
RGCC regulator of cell cycle -0.0102224
BIRC3 baculoviral IAP repeat containing 3 -0.0102202
LY6D lymphocyte antigen 6 complex, locus D -0.0101645
GBP2 guanylate binding protein 2, interferon-inducible -0.0101528
AIM2 absent in melanoma 2 -0.0101514
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.0101484
SP110 SP110 nuclear body protein -0.0101092
IL1RN interleukin 1 receptor antagonist -0.0100946
HSPB8 heat shock 22kDa protein 8 -0.0100252
PMP2 peripheral myelin protein 2 -0.0100242
FABP7 fatty acid binding protein 7, brain -0.00996302
ELF1 E74-like factor 1 (ets domain transcription factor) -0.0098374
PDE4B phosphodiesterase 4B, cAMP-specific -0.00979058
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00978831
S100A7 S100 calcium binding protein A7 -0.00969315
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.00968187
TRIM16 tripartite motif containing 16 -0.0096571
PRKCA protein kinase C, alpha -0.00960794
LRP4 low density lipoprotein receptor-related protein 4 -0.00959129
CD99 CD99 molecule -0.0095855
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00956741
ZMAT3 zinc finger, matrin-type 3 -0.0095546
KRT14 keratin 14, type I -0.0095346
MX2 MX dynamin-like GTPase 2 -0.00953107
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 -0.00949184
CHN1 chimerin 1 -0.00947264
ELL2 elongation factor, RNA polymerase II, 2 -0.00945827
TUBB2A tubulin, beta 2A class IIa -0.00944535
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -0.00944254
LEF1 lymphoid enhancer-binding factor 1 -0.00938084
ADGRG2 adhesion G protein-coupled receptor G2 -0.00935309
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.00934072
APOLD1 apolipoprotein L domain containing 1 -0.0093224
SHTN1 shootin 1 -0.0092718
MYOF myoferlin -0.0092325
THBS2 thrombospondin 2 -0.00920137
LAMB3 laminin, beta 3 -0.00915012
CADM1 cell adhesion molecule 1 -0.00914664
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00909028
ATOX1 antioxidant 1 copper chaperone -0.00905994
TGFBI transforming growth factor, beta-induced, 68kDa -0.00905912
ERBB3 erb-b2 receptor tyrosine kinase 3 -0.00905864
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00904744
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00899668
ODC1 ornithine decarboxylase 1 -0.00895796
MAGEA4 melanoma antigen family A4 -0.0089347
ABLIM1 actin binding LIM protein 1 -0.00889366
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00888848
L1CAM L1 cell adhesion molecule -0.0088855
CCR7 chemokine (C-C motif) receptor 7 -0.00883598
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00882835
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.00880243
ETFB electron-transfer-flavoprotein, beta polypeptide -0.0088007
IFI44 interferon-induced protein 44 -0.00879288
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.00877299
GNAS GNAS complex locus -0.00876414
LAMA3 laminin, alpha 3 -0.00876004
PI3 peptidase inhibitor 3, skin-derived -0.0087315
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00872332
RSL1D1 ribosomal L1 domain containing 1 -0.00871386
HIST1H2AC histone cluster 1, H2ac -0.00871274
CREM cAMP responsive element modulator -0.00870722
COL15A1 collagen, type XV, alpha 1 -0.00868815
NCOA4 nuclear receptor coactivator 4 -0.0086682
MAL mal, T-cell differentiation protein -0.00864703
CHIC2 cysteine-rich hydrophobic domain 2 -0.00863548
KLF6 Kruppel-like factor 6 -0.00863002
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00862734
TNNC1 troponin C type 1 (slow) -0.00862282
CASP7 caspase 7, apoptosis-related cysteine peptidase -0.00861323
CDC123 cell division cycle 123 -0.00859581
TRIM22 tripartite motif containing 22 -0.00858338
MTIF2 mitochondrial translational initiation factor 2 -0.00857863
MOCOS molybdenum cofactor sulfurase -0.00856979
HOXB7 homeobox B7 -0.00855143
SELE selectin E -0.00854509
DAXX death-domain associated protein -0.00852544
CSTB cystatin B (stefin B) -0.00851398
RTCA RNA 3'-terminal phosphate cyclase -0.00850643
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.00850434
PABPC3 poly(A) binding protein, cytoplasmic 3 -0.00850371
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00848131
POPDC3 popeye domain containing 3 -0.00847688
RBM47 RNA binding motif protein 47 -0.00847613
KRT6A keratin 6A, type II -0.00847529
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -0.00844969
SIK1 salt-inducible kinase 1 -0.00844222
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.00843088
NLRP2 NLR family, pyrin domain containing 2 -0.00842246
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00840536
PERP PERP, TP53 apoptosis effector -0.00840208
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.008378
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.00837715
GLRX glutaredoxin (thioltransferase) -0.00837225
ANOS1 anosmin 1 -0.00835799
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -0.00835578
SPRR1B small proline-rich protein 1B -0.0083376
PTHLH parathyroid hormone-like hormone -0.00833462
TFF1 trefoil factor 1 -0.00832628
PIGP phosphatidylinositol glycan anchor biosynthesis, class P -0.00832274
GRB7 growth factor receptor-bound protein 7 -0.00826559
LMCD1 LIM and cysteine-rich domains 1 -0.00825893
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -0.00825701
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00824942
PLEK2 pleckstrin 2 -0.0082374
TBX3 T-box 3 -0.0082345
SERINC5 serine incorporator 5 -0.00821618
OPTN optineurin -0.00820683
MOXD1 monooxygenase, DBH-like 1 -0.00820249
FHL2 four and a half LIM domains 2 -0.00818918
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.00818078
HOMER2 homer scaffolding protein 2 -0.00816229
CHGB chromogranin B -0.00815558
CHI3L2 chitinase 3-like 2 -0.00815171
NELL2 NEL-like 2 (chicken) -0.00814987
TGM2 transglutaminase 2 -0.00814679
USP18 ubiquitin specific peptidase 18 -0.00814292
CLCA4 chloride channel accessory 4 -0.00813112
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.00812649
ADAT1 adenosine deaminase, tRNA-specific 1 -0.00807738
MXRA5 matrix-remodelling associated 5 -0.00807706
MAGEA3 melanoma antigen family A3 -0.00807547
ADAM10 ADAM metallopeptidase domain 10 -0.00806931
PRNP prion protein -0.00806577
LPXN leupaxin -0.00802668
CCT4 chaperonin containing TCP1, subunit 4 (delta) -0.00802205
PRSS23 protease, serine, 23 -0.00799992
EGFL6 EGF-like-domain, multiple 6 -0.00799403
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00798397
FA2H fatty acid 2-hydroxylase -0.00797585
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.00797346
ATF6 activating transcription factor 6 -0.00795611
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.00793821
EDN3 endothelin 3 -0.00792992
BAG3 BCL2-associated athanogene 3 -0.00792037
CH25H cholesterol 25-hydroxylase -0.00790532
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.00789436
CNPY3 canopy FGF signaling regulator 3 -0.00788979
IFIH1 interferon induced with helicase C domain 1 -0.00787869
NBR1 neighbor of BRCA1 gene 1 -0.00787365
HLA-DRA major histocompatibility complex, class II, DR alpha -0.00787054
MAGEA1 melanoma antigen family A1 -0.00784931
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00784101
ETHE1 ethylmalonic encephalopathy 1 -0.00783676
CHPT1 choline phosphotransferase 1 -0.00783167
BTG3 BTG family, member 3 -0.00782937
HSPA8 heat shock 70kDa protein 8 -0.00782544
CD59 CD59 molecule, complement regulatory protein -0.00776801
CD93 CD93 molecule -0.00774911
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.00774596
PHF11 PHD finger protein 11 -0.00774138
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -0.00772221
RCAN1 regulator of calcineurin 1 -0.00772008
XIC X chromosome inactivation center -0.0077188
TRIM38 tripartite motif containing 38 -0.00770557
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -0.00770258
FXYD3 FXYD domain containing ion transport regulator 3 -0.00770147
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.00766901
PLSCR1 phospholipid scramblase 1 -0.00763723
CCNG1 cyclin G1 -0.00762982
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00762097
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.00762007
FXYD5 FXYD domain containing ion transport regulator 5 -0.00761565
S100B S100 calcium binding protein B -0.00761383
RPP40 ribonuclease P/MRP 40kDa subunit -0.00758802
COPA coatomer protein complex, subunit alpha -0.0075867
ODAM odontogenic, ameloblast asssociated -0.00758342
DCTN4 dynactin 4 (p62) -0.00757381
CST1 cystatin SN -0.00757071
COCH cochlin -0.00756335
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00751876
GAS7 growth arrest-specific 7 -0.007505
NEU1 sialidase 1 (lysosomal sialidase) -0.00749487