BCL10 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description B-cell CLL/lymphoma 10|This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8915)
External Link https://ncbi.nlm.nih.gov/gene/8915
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Genes

499 genes differentially expressed following the BCL10 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
PLK1 polo-like kinase 1 0.0177778
MT1HL1 metallothionein 1H-like 1 0.0153522
MT1H metallothionein 1H 0.0149796
MT1X metallothionein 1X 0.0147545
MT1F metallothionein 1F 0.014517
MT1G metallothionein 1G 0.0125394
CYBA cytochrome b-245, alpha polypeptide 0.0125162
RNASET2 ribonuclease T2 0.0124013
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.012154
MT2A metallothionein 2A 0.0121229
KRT7 keratin 7, type II 0.0120542
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0116042
EIF5A eukaryotic translation initiation factor 5A 0.0114061
LMO2 LIM domain only 2 (rhombotin-like 1) 0.0113436
EPCAM epithelial cell adhesion molecule 0.0113423
PROM1 prominin 1 0.0111052
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.0109884
SNAP25 synaptosomal-associated protein, 25kDa 0.0109669
ANXA1 annexin A1 0.0108225
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.010618
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.0104155
STXBP2 syntaxin binding protein 2 0.0102447
C3 complement component 3 0.0101552
HSPA1A heat shock 70kDa protein 1A 0.0101544
MT1E metallothionein 1E 0.0101268
VLDLR very low density lipoprotein receptor 0.00982195
MGP matrix Gla protein 0.00964034
PEG3 paternally expressed 3 0.00963313
CXADR coxsackie virus and adenovirus receptor 0.00960524
ACAA1 acetyl-CoA acyltransferase 1 0.00958423
C8ORF4 chromosome 8 open reading frame 4 0.00945975
F3 coagulation factor III (thromboplastin, tissue factor) 0.00939522
MT1M metallothionein 1M 0.00922152
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00919257
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.00904113
FXYD5 FXYD domain containing ion transport regulator 5 0.00891072
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.00887024
MMP7 matrix metallopeptidase 7 0.00875657
TESC tescalcin 0.00870308
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.00866873
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00866554
GUCY2C guanylate cyclase 2C 0.00862396
PDE8B phosphodiesterase 8B 0.00858188
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.00856831
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00856805
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00856745
ETFB electron-transfer-flavoprotein, beta polypeptide 0.00855876
PLIN3 perilipin 3 0.00846524
ASRGL1 asparaginase like 1 0.008339
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00831853
GDE1 glycerophosphodiester phosphodiesterase 1 0.00827374
SLC35G2 solute carrier family 35, member G2 0.00813332
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.0080714
NEBL nebulette 0.00806302
LINC00623 long intergenic non-protein coding RNA 623 0.00806065
NT5E 5'-nucleotidase, ecto (CD73) 0.0080444
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 0.0080187
CHGB chromogranin B 0.00801191
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00795787
GYPC glycophorin C (Gerbich blood group) 0.00794692
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00794375
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.00793188
PDE4B phosphodiesterase 4B, cAMP-specific 0.00792783
SORBS3 sorbin and SH3 domain containing 3 0.00790594
RFC2 replication factor C (activator 1) 2, 40kDa 0.00786623
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00779715
ZMAT3 zinc finger, matrin-type 3 0.00776298
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.00772809
MARCO macrophage receptor with collagenous structure 0.00763178
CCK cholecystokinin 0.00755042
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00747456
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00742751
PRNP prion protein 0.00738379
ZYX zyxin 0.0073698
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.00725476
ERP44 endoplasmic reticulum protein 44 0.00723484
LRRN3 leucine rich repeat neuronal 3 0.00719262
OPHN1 oligophrenin 1 0.00717585
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00717303
CIB1 calcium and integrin binding 1 (calmyrin) 0.00716374
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.00716365
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00712347
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00710536
NELL2 NEL-like 2 (chicken) 0.00708749
GNG4 guanine nucleotide binding protein (G protein), gamma 4 0.00706734
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00706576
RGS10 regulator of G-protein signaling 10 0.00705891
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.00701281
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00701126
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00699591
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.0069644
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00695295
RAB25 RAB25, member RAS oncogene family 0.00695031
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.0069108
SYT1 synaptotagmin I 0.00685818
COL9A3 collagen, type IX, alpha 3 0.00682692
RAB5C RAB5C, member RAS oncogene family 0.00681108
NCALD neurocalcin delta 0.00679473
FKBP5 FK506 binding protein 5 0.00673969
IQCK IQ motif containing K 0.00671416
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.00665051
CD14 CD14 molecule 0.00664593
BSG basigin (Ok blood group) 0.00663594
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00661397
CLDN10 claudin 10 0.00661359
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00659323
HIGD2A HIG1 hypoxia inducible domain family, member 2A 0.00659167
FLNA filamin A, alpha 0.00656987
BAX BCL2-associated X protein 0.0065632
SGK1 serum/glucocorticoid regulated kinase 1 0.00655738
ESR1 estrogen receptor 1 0.0065566
PLIN2 perilipin 2 0.00654707
VCAN versican 0.00654297
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00652931
LEPROT leptin receptor overlapping transcript 0.00651745
LPAR6 lysophosphatidic acid receptor 6 0.00651101
FOXC1 forkhead box C1 0.00649558
FABP7 fatty acid binding protein 7, brain 0.00648652
PEBP1 phosphatidylethanolamine binding protein 1 0.00646484
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.00645182
TMEM243 transmembrane protein 243, mitochondrial 0.00643047
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.00641983
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.0064114
CFD complement factor D (adipsin) 0.00641012
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 0.00640782
EDN3 endothelin 3 0.00638882
RSL1D1 ribosomal L1 domain containing 1 0.00636884
GPM6B glycoprotein M6B 0.00636208
TFRC transferrin receptor 0.00635006
LEFTY1 left-right determination factor 1 0.00634296
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.00633563
NANS N-acetylneuraminic acid synthase 0.00630133
SH3YL1 SH3 and SYLF domain containing 1 0.00628507
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00628149
DNASE2 deoxyribonuclease II, lysosomal 0.00626743
CTSS cathepsin S 0.00624889
PRR13 proline rich 13 0.00622729
CXCL8 chemokine (C-X-C motif) ligand 8 0.00619096
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00617091
COG7 component of oligomeric golgi complex 7 0.00615741
CRAT carnitine O-acetyltransferase 0.00614496
EMP2 epithelial membrane protein 2 0.00614064
TJP3 tight junction protein 3 0.00612522
TCF7 transcription factor 7 (T-cell specific, HMG-box) 0.0061062
ELOVL2 ELOVL fatty acid elongase 2 0.00609458
SPATA2L spermatogenesis associated 2-like 0.00608495
THBS2 thrombospondin 2 0.00606131
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00605677
AKIRIN1 akirin 1 0.00605185
TRPS1 trichorhinophalangeal syndrome I 0.0060518
SMAD3 SMAD family member 3 0.00604191
GAP43 growth associated protein 43 0.00603989
KRT19 keratin 19, type I 0.00603436
MYH11 myosin, heavy chain 11, smooth muscle 0.00601671
NRN1 neuritin 1 0.00600584
BID BH3 interacting domain death agonist 0.00600261
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.0058755
MAN1A1 mannosidase, alpha, class 1A, member 1 0.00587292
DAZAP2 DAZ associated protein 2 0.00586921
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.00586678
TLE5 TLE family member 5, transcriptional modulator 0.00585911
AKAP12 A kinase (PRKA) anchor protein 12 0.00585642
PDK4 pyruvate dehydrogenase kinase, isozyme 4 0.00585439
PHKA1 phosphorylase kinase, alpha 1 (muscle) 0.00584804
PLLP plasmolipin 0.00584758
KYNU kynureninase 0.00584635
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.00584193
CLDN8 claudin 8 0.00583179
TSPAN1 tetraspanin 1 0.00582748
NPEPL1 aminopeptidase-like 1 0.00581913
DMD dystrophin 0.00578743
SORBS2 sorbin and SH3 domain containing 2 0.00578313
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.00576668
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00575703
MZT2A mitotic spindle organizing protein 2A 0.00574598
NT5DC2 5'-nucleotidase domain containing 2 0.00574388
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.00572584
IL6ST interleukin 6 signal transducer 0.00570693
LXN latexin 0.0056817
KRT81 keratin 81, type II 0.00567033
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.00565842
VIPR1 vasoactive intestinal peptide receptor 1 0.0056462
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.00564161
ISG20 interferon stimulated exonuclease gene 20kDa 0.00564144
FDX1 ferredoxin 1 0.00562918
MVP major vault protein 0.00562493
UBXN7 UBX domain protein 7 0.00561466
ANXA2P2 annexin A2 pseudogene 2 0.00560883
LZTS3 leucine zipper, putative tumor suppressor family member 3 0.00560254
CHPT1 choline phosphotransferase 1 0.00558713
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.00557667
OSMR oncostatin M receptor 0.00557531
NRIP3 nuclear receptor interacting protein 3 0.00556647
TMBIM1 transmembrane BAX inhibitor motif containing 1 0.00555882
ZNF91 zinc finger protein 91 0.00555177
CYRIA CYFIP related Rac1 interactor A 0.0055461
EFNA1 ephrin-A1 0.0055298
TLR4 toll-like receptor 4 0.00552354
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.00550079
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.0055007
MSLN mesothelin 0.00549422
COX5A cytochrome c oxidase subunit Va 0.0054924
CDCA3 cell division cycle associated 3 0.00547888
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 0.00545329
PTK2 protein tyrosine kinase 2 0.00543709
HOMER1 homer scaffolding protein 1 0.00542648
CST1 cystatin SN 0.00541961
YIPF5 Yip1 domain family, member 5 0.0054031
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.0054022
FAM107A family with sequence similarity 107, member A 0.00539201
VAMP8 vesicle-associated membrane protein 8 0.00536812
MYBPC1 myosin binding protein C, slow type 0.00535683
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00535424
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.00535027
MRPL18 mitochondrial ribosomal protein L18 0.00534649
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00534377
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 0.00534011
MGLL monoglyceride lipase 0.00533239
ZNF652 zinc finger protein 652 0.00532869
POR P450 (cytochrome) oxidoreductase 0.00531877
INSR insulin receptor 0.00531384
MX1 MX dynamin-like GTPase 1 0.00531359
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00529797
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.00529297
TPD52L1 tumor protein D52-like 1 0.00529156
S100A8 S100 calcium binding protein A8 0.00529028
ZNF331 zinc finger protein 331 0.0052846
LMCD1 LIM and cysteine-rich domains 1 0.00527213
GRB14 growth factor receptor-bound protein 14 0.00526752
FYB1 FYN binding protein 1 0.00526705
RETREG1 reticulophagy regulator 1 0.00526639
ACP1 acid phosphatase 1, soluble 0.00525892
METTL7A methyltransferase like 7A 0.00525655
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.00525284
CCND3 cyclin D3 0.00525125
COBL cordon-bleu WH2 repeat protein 0.00524823
MPZL2 myelin protein zero-like 2 0.00523172
DDB2 damage-specific DNA binding protein 2, 48kDa 0.00523091
TCP1 t-complex 1 0.00521998
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 0.00521414
HIST3H2A histone cluster 3, H2a 0.00521337
STEAP3 STEAP family member 3, metalloreductase 0.00520887
S100A11 S100 calcium binding protein A11 0.00520166
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 0.00519696
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.00519394
RTCA RNA 3'-terminal phosphate cyclase 0.00518889
CORO1B coronin, actin binding protein, 1B 0.005171
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00516135
TEX10 testis expressed 10 0.00515912
OAT ornithine aminotransferase 0.00513448

decreased expression

Symbol Name Standardized Value
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0133142
JCHAIN joining chain of multimeric IgA and IgM -0.0114852
STK26 serine/threonine protein kinase 26 -0.0107457
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.0106934
CXCL13 chemokine (C-X-C motif) ligand 13 -0.0106208
CASP7 caspase 7, apoptosis-related cysteine peptidase -0.0101626
IDO1 indoleamine 2,3-dioxygenase 1 -0.0100765
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0100443
ARG1 arginase 1 -0.00996762
EFNB2 ephrin-B2 -0.0099664
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00995547
DUSP5 dual specificity phosphatase 5 -0.00989874
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00974456
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00966488
CPA3 carboxypeptidase A3 (mast cell) -0.009285
FSTL1 follistatin-like 1 -0.00925029
CST7 cystatin F (leukocystatin) -0.00924393
CNN3 calponin 3, acidic -0.00922604
LOXL1 lysyl oxidase-like 1 -0.00906536
CD69 CD69 molecule -0.00894237
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00890918
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.00884436
RAB38 RAB38, member RAS oncogene family -0.00880466
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00880405
GRSF1 G-rich RNA sequence binding factor 1 -0.00869888
KRT14 keratin 14, type I -0.00864293
CHIC2 cysteine-rich hydrophobic domain 2 -0.00859826
VCAM1 vascular cell adhesion molecule 1 -0.00855702
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00844118
SFN stratifin -0.00841537
TRIB2 tribbles pseudokinase 2 -0.00836656
S100A2 S100 calcium binding protein A2 -0.00831944
UBL3 ubiquitin-like 3 -0.00825931
TARP TCR gamma alternate reading frame protein -0.00822031
PDGFC platelet derived growth factor C -0.00818816
FBN2 fibrillin 2 -0.00803589
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00800629
SUCO SUN domain containing ossification factor -0.00793379
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00791394
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.00789443
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00788048
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.00783276
CCL19 chemokine (C-C motif) ligand 19 -0.00781087
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00780643
NUSAP1 nucleolar and spindle associated protein 1 -0.00777679
KDM5D lysine (K)-specific demethylase 5D -0.00775895
TXLNA taxilin alpha -0.00773942
DCK deoxycytidine kinase -0.00773589
PLAGL1 pleiomorphic adenoma gene-like 1 -0.00766681
DSC1 desmocollin 1 -0.00766388
CYB5A cytochrome b5 type A (microsomal) -0.00763938
FBXO11 F-box protein 11 -0.00759491
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.00749334
SNAI2 snail family zinc finger 2 -0.00749235
TYRP1 tyrosinase-related protein 1 -0.00735645
CBX1 chromobox homolog 1 -0.00733595
MYB v-myb avian myeloblastosis viral oncogene homolog -0.00732672
TPSAB1 tryptase alpha/beta 1 -0.0073017
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00727343
WT1 Wilms tumor 1 -0.00718803
PLA1A phospholipase A1 member A -0.00714647
PEG10 paternally expressed 10 -0.00711743
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 -0.00711449
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.00710861
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00709933
CCN3 cellular communication network factor 3 -0.00709732
THAP12 THAP domain containing 12 -0.00701328
GET1 guided entry of tail-anchored proteins factor 1 -0.00698733
TENT4A terminal nucleotidyltransferase 4A -0.00696641
CALML3 calmodulin-like 3 -0.00687474
MN1 meningioma (disrupted in balanced translocation) 1 -0.00687316
FGFR1 fibroblast growth factor receptor 1 -0.00685423
ZWINT ZW10 interacting kinetochore protein -0.00684751
GBP1 guanylate binding protein 1, interferon-inducible -0.00684154
LYST lysosomal trafficking regulator -0.00679233
SMG7 SMG7 nonsense mediated mRNA decay factor -0.00676659
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00675737
GLS glutaminase -0.00672188
CCNG2 cyclin G2 -0.00669024
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00666505
ZBTB18 zinc finger and BTB domain containing 18 -0.00664218
DROSHA drosha, ribonuclease type III -0.00663877
SDC3 syndecan 3 -0.00660468
PALLD palladin, cytoskeletal associated protein -0.00660264
CREB1 cAMP responsive element binding protein 1 -0.00658228
RIT1 Ras-like without CAAX 1 -0.00655725
GOLIM4 golgi integral membrane protein 4 -0.00652542
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.0065158
RGS1 regulator of G-protein signaling 1 -0.0065121
TUBB2A tubulin, beta 2A class IIa -0.00649865
BMP2K BMP2 inducible kinase -0.0064867
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.00647901
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00647091
KIFAP3 kinesin-associated protein 3 -0.00645483
ARHGAP29 Rho GTPase activating protein 29 -0.00642407
SOCS5 suppressor of cytokine signaling 5 -0.00639758
TMEM131L transmembrane 131 like -0.00638656
PLAT plasminogen activator, tissue -0.00637183
PMEL premelanosome protein -0.00636751
LPAR1 lysophosphatidic acid receptor 1 -0.00635501
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -0.00634916
TLE4 transducin-like enhancer of split 4 -0.00633497
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.0063239
NISCH nischarin -0.00631026
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.00628036
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -0.00627997
BRD1 bromodomain containing 1 -0.00626765
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -0.00621612
TRRAP transformation/transcription domain-associated protein -0.00620697
RSAD1 radical S-adenosyl methionine domain containing 1 -0.00619958
GPR88 G protein-coupled receptor 88 -0.00617512
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00617318
USP48 ubiquitin specific peptidase 48 -0.00613329
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00613164
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) -0.00612987
RUBCN rubicon autophagy regulator -0.00612885
PAPOLA poly(A) polymerase alpha -0.00612454
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.00607327
DAPK1 death-associated protein kinase 1 -0.00607179
LAMP2 lysosomal-associated membrane protein 2 -0.00601138
ODC1 ornithine decarboxylase 1 -0.00601129
IGHMBP2 immunoglobulin mu binding protein 2 -0.00599822
COLEC12 collectin sub-family member 12 -0.00595974
TARDBP TAR DNA binding protein -0.00595733
BST2 bone marrow stromal cell antigen 2 -0.00595104
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0059478
TRIO trio Rho guanine nucleotide exchange factor -0.00593272
G0S2 G0/G1 switch 2 -0.0058692
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00586322
KANK2 KN motif and ankyrin repeat domains 2 -0.00584259
ADARB1 adenosine deaminase, RNA-specific, B1 -0.00583302
HMGN3 high mobility group nucleosomal binding domain 3 -0.00582865
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.00582815
IL18 interleukin 18 -0.00582746
SCGB1D2 secretoglobin, family 1D, member 2 -0.00582504
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00580911
CDK19 cyclin-dependent kinase 19 -0.00579095
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -0.00576212
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.00576127
ALG8 ALG8, alpha-1,3-glucosyltransferase -0.00575388
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') -0.00574025
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00573712
ZDHHC6 zinc finger, DHHC-type containing 6 -0.00571688
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.00571655
PFKM phosphofructokinase, muscle -0.0057152
TFEC transcription factor EC -0.00570362
INTS3 integrator complex subunit 3 -0.0056935
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.0056906
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00569024
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.00568976
TRAF5 TNF receptor-associated factor 5 -0.00567161
ANPEP alanyl (membrane) aminopeptidase -0.00567067
TTC37 tetratricopeptide repeat domain 37 -0.00566809
GUCY1B3 guanylate cyclase 1, soluble, beta 3 -0.00566745
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) -0.00566303
NXF3 nuclear RNA export factor 3 -0.00564833
KRT5 keratin 5, type II -0.00564185
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00563449
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.00560123
TUBB2B tubulin, beta 2B class IIb -0.00560094
UXT ubiquitously-expressed, prefoldin-like chaperone -0.00559387
TYR tyrosinase -0.00559047
BMI1 BMI1 proto-oncogene, polycomb ring finger -0.00557457
SPEN spen family transcriptional repressor -0.00555171
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -0.00553064
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.00552682
PLXNC1 plexin C1 -0.00552633
KCTD5 potassium channel tetramerization domain containing 5 -0.00549794
TRMT5 tRNA methyltransferase 5 -0.00549716
GSTA4 glutathione S-transferase alpha 4 -0.00549413
CLCA2 chloride channel accessory 2 -0.00548121
C1QA complement component 1, q subcomponent, A chain -0.00543623
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -0.00542799
MPRIP myosin phosphatase Rho interacting protein -0.00542789
C5ORF22 chromosome 5 open reading frame 22 -0.00542768
CHERP calcium homeostasis endoplasmic reticulum protein -0.00542609
DGS2 DiGeorge syndrome/velocardiofacial syndrome complex 2 -0.00540487
DIPK1A divergent protein kinase domain 1A -0.00539892
RP2 retinitis pigmentosa 2 (X-linked recessive) -0.00539324
MICALL1 MICAL-like 1 -0.0053884
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) -0.00538192
ADAM9 ADAM metallopeptidase domain 9 -0.00537589
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 -0.00536567
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -0.00536015
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.00534846
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00534628
TARS1 threonyl-tRNA synthetase 1 -0.00534571
BTBD3 BTB (POZ) domain containing 3 -0.0053315
KIAA1109 KIAA1109 -0.00532592
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.005316
MGAM maltase-glucoamylase -0.00529962
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.00529246
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -0.00528993
NAV3 neuron navigator 3 -0.00526591
POLB polymerase (DNA directed), beta -0.00526018
ISL1 ISL LIM homeobox 1 -0.0052564
HIST1H2AC histone cluster 1, H2ac -0.0052516
REXO2 RNA exonuclease 2 -0.00523248
TMEM14A transmembrane protein 14A -0.00522139
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.00521106
PANK3 pantothenate kinase 3 -0.00518723
MTCL1 microtubule crosslinking factor 1 -0.00517743
SMYD3 SET and MYND domain containing 3 -0.00516822
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 -0.00515805
CTSK cathepsin K -0.00515674
KAT2B K(lysine) acetyltransferase 2B -0.00515582
CD209 CD209 molecule -0.0051548
CDK11A cyclin-dependent kinase 11A -0.00515039
EXOC7 exocyst complex component 7 -0.00514657
TUG1 taurine up-regulated 1 (non-protein coding) -0.00513948
XPO1 exportin 1 -0.005132
NUP155 nucleoporin 155kDa -0.00512858
NEO1 neogenin 1 -0.00510948
PILRB paired immunoglobin-like type 2 receptor beta -0.00510756
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like -0.00510598
PLXDC1 plexin domain containing 1 -0.00510349
AP5M1 adaptor-related protein complex 5, mu 1 subunit -0.00510279
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00510047
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.0050985
THY1 Thy-1 cell surface antigen -0.00508361
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -0.00507325
AOC1 amine oxidase, copper containing 1 -0.00507315
HMGB1 high mobility group box 1 -0.00507294
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 -0.00506882
RASA1 RAS p21 protein activator (GTPase activating protein) 1 -0.00506694
DAAM2 dishevelled associated activator of morphogenesis 2 -0.00505678
DENND5A DENN/MADD domain containing 5A -0.00505139
AUTS2 autism susceptibility candidate 2 -0.00504806
PNOC prepronociceptin -0.00504719
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00504709
CASC3 cancer susceptibility candidate 3 -0.00504614
COL16A1 collagen, type XVI, alpha 1 -0.00504486
MMP9 matrix metallopeptidase 9 -0.00504362
NOTCH2 notch 2 -0.00502338
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) -0.0050212
BPI bactericidal/permeability-increasing protein -0.00502026
TMEM176B transmembrane protein 176B -0.00501812
ATP7A ATPase, Cu++ transporting, alpha polypeptide -0.00501154
AVL9 AVL9 homolog (S. cerevisiase) -0.00500858
TNC tenascin C -0.00500147
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 -0.00499082
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00499029
KHNYN KH and NYN domain containing -0.00498073
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00496919
RANBP1 RAN binding protein 1 -0.00496284
MBNL2 muscleblind-like splicing regulator 2 -0.00495277
PKP1 plakophilin 1 -0.00494483
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -0.0049395
BHMT2 betaine--homocysteine S-methyltransferase 2 -0.00493771