BCL2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description B-cell CLL/lymphoma 2|This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 596)
External Link https://ncbi.nlm.nih.gov/gene/596
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Genes

500 genes differentially expressed following the BCL2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MMP1 matrix metallopeptidase 1 0.0145185
SCG5 secretogranin V 0.0119286
SFRP4 secreted frizzled-related protein 4 0.0110306
CLEC11A C-type lectin domain family 11, member A 0.0104231
PCP4 Purkinje cell protein 4 0.00993052
HSPB1 heat shock 27kDa protein 1 0.00965174
CKS2 CDC28 protein kinase regulatory subunit 2 0.00954718
ECM1 extracellular matrix protein 1 0.00884545
LY6E lymphocyte antigen 6 complex, locus E 0.00869969
GUSBP3 glucuronidase, beta pseudogene 3 0.00860645
HSPA1A heat shock 70kDa protein 1A 0.00856302
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00825845
PLAAT3 phospholipase A and acyltransferase 3 0.00821602
CD320 CD320 molecule 0.00817258
ZNF586 zinc finger protein 586 0.00803924
TYMS thymidylate synthetase 0.00798636
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00796351
PTGIS prostaglandin I2 (prostacyclin) synthase 0.00759171
PTP4A3 protein tyrosine phosphatase type IVA, member 3 0.00738579
PCLAF PCNA clamp associated factor 0.00735619
AURKB aurora kinase B 0.0073103
NRCAM neuronal cell adhesion molecule 0.00718927
HOMER3 homer scaffolding protein 3 0.00717559
DYNLL1 dynein, light chain, LC8-type 1 0.00713757
S100A4 S100 calcium binding protein A4 0.00713005
ESR1 estrogen receptor 1 0.00711052
C3ORF14 chromosome 3 open reading frame 14 0.00709694
PYCARD PYD and CARD domain containing 0.00705783
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00705568
CDKN2A cyclin-dependent kinase inhibitor 2A 0.00696319
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00695504
TXNDC9 thioredoxin domain containing 9 0.00693101
ZBTB20 zinc finger and BTB domain containing 20 0.00691174
RAP1GAP2 RAP1 GTPase activating protein 2 0.0068985
LCN2 lipocalin 2 0.00687619
SMYD3 SET and MYND domain containing 3 0.00686672
CREB1 cAMP responsive element binding protein 1 0.00685493
C7 complement component 7 0.00685079
LAMP5 lysosomal-associated membrane protein family, member 5 0.00682619
PKM pyruvate kinase, muscle 0.00673529
VCAM1 vascular cell adhesion molecule 1 0.00667977
COMP cartilage oligomeric matrix protein 0.00667911
CENPU centromere protein U 0.00666719
TSPAN7 tetraspanin 7 0.00663066
CCND2 cyclin D2 0.00660819
MTA1 metastasis associated 1 0.00659243
AMOTL2 angiomotin like 2 0.0065687
SNAP25 synaptosomal-associated protein, 25kDa 0.00654049
THBS2 thrombospondin 2 0.00650837
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00649099
IPO13 importin 13 0.00641388
CEL carboxyl ester lipase 0.00639787
S100A8 S100 calcium binding protein A8 0.00630624
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00627785
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00622556
MPRIP myosin phosphatase Rho interacting protein 0.006194
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00619151
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.006165
CYBA cytochrome b-245, alpha polypeptide 0.00615041
AEBP1 AE binding protein 1 0.00611536
METRN meteorin, glial cell differentiation regulator 0.00608127
PCNA proliferating cell nuclear antigen 0.00606993
PTK2B protein tyrosine kinase 2 beta 0.00598181
ST18 suppression of tumorigenicity 18, zinc finger 0.00598062
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00596802
ISYNA1 inositol-3-phosphate synthase 1 0.00591862
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.00590831
EXT1 exostosin glycosyltransferase 1 0.00588728
ZFPM2 zinc finger protein, FOG family member 2 0.00587313
AMIGO2 adhesion molecule with Ig-like domain 2 0.00586954
H2AX H2A.X variant histone 0.00585408
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.00580733
CRYAB crystallin, alpha B 0.00580622
BANP BTG3 associated nuclear protein 0.00577712
PEG10 paternally expressed 10 0.00576793
ZNF544 zinc finger protein 544 0.00570521
LTBP2 latent transforming growth factor beta binding protein 2 0.00567359
HK2 hexokinase 2 0.00567004
C2CD2 C2 calcium-dependent domain containing 2 0.00563351
LUM lumican 0.00561068
PTPRD protein tyrosine phosphatase, receptor type, D 0.00559556
MFAP5 microfibrillar associated protein 5 0.00557941
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.00556632
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00554276
NOTCH2NL notch 2 N-terminal like 0.00552847
CTSK cathepsin K 0.00551993
COL6A2 collagen, type VI, alpha 2 0.0055138
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.00551353
RGS16 regulator of G-protein signaling 16 0.00549948
NXN nucleoredoxin 0.00549548
ING3 inhibitor of growth family, member 3 0.00549447
PHACTR2 phosphatase and actin regulator 2 0.00547239
TMEM126B transmembrane protein 126B 0.00542335
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00541218
LYN LYN proto-oncogene, Src family tyrosine kinase 0.00540474
NPTX1 neuronal pentraxin I 0.00536316
CAPN1 calpain 1, (mu/I) large subunit 0.00535827
ZNF160 zinc finger protein 160 0.0053515
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.00529438
MBL2 mannose-binding lectin (protein C) 2, soluble 0.00529435
PLN phospholamban 0.00528669
COX17 COX17 cytochrome c oxidase copper chaperone 0.00526721
DNM1 dynamin 1 0.00524483
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 0.00524279
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.00521295
QPRT quinolinate phosphoribosyltransferase 0.00520826
NREP neuronal regeneration related protein 0.00520501
LPAR1 lysophosphatidic acid receptor 1 0.00519447
FGL2 fibrinogen-like 2 0.00517749
CYBB cytochrome b-245, beta polypeptide 0.0051551
MFSD10 major facilitator superfamily domain containing 10 0.00513419
SNX7 sorting nexin 7 0.00512341
WSB1 WD repeat and SOCS box containing 1 0.00512318
SLIT2 slit homolog 2 (Drosophila) 0.00511744
ASPN asporin 0.00511209
MXRA5 matrix-remodelling associated 5 0.00511155
ABHD17A abhydrolase domain containing 17A 0.00509148
MLXIP MLX interacting protein 0.00507973
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00507599
CTSD cathepsin D 0.00507332
TRIO trio Rho guanine nucleotide exchange factor 0.00505293
G0S2 G0/G1 switch 2 0.00504119
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.00504015
RELN reelin 0.00502412
SNRPG small nuclear ribonucleoprotein polypeptide G 0.00501409
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.00500956
ZNF329 zinc finger protein 329 0.00498722
KDM5D lysine (K)-specific demethylase 5D 0.00498092
BANF1 barrier to autointegration factor 1 0.00497979
EML3 echinoderm microtubule associated protein like 3 0.00496817
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.0049637
COQ8A coenzyme Q8A 0.00496363
TSPAN12 tetraspanin 12 0.00495283
SMAD7 SMAD family member 7 0.00495055
NPY neuropeptide Y 0.00494586
RPL39L ribosomal protein L39-like 0.00492107
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00492068
PLIN1 perilipin 1 0.00491664
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.0049155
FBXW12 F-box and WD repeat domain containing 12 0.00489666
BST2 bone marrow stromal cell antigen 2 0.0048803
ZNF721 zinc finger protein 721 0.00484323
NID2 nidogen 2 (osteonidogen) 0.00484289
KLK5 kallikrein-related peptidase 5 0.00484137
HRASLS HRAS-like suppressor 0.00483629
MN1 meningioma (disrupted in balanced translocation) 1 0.00482943
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.00481313
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00480594
FBLN1 fibulin 1 0.00480459
WT1 Wilms tumor 1 0.00480162
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00480029
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.00479224
DCN decorin 0.00478044
WASF1 WAS protein family, member 1 0.00476503
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00472859
SPTSSA serine palmitoyltransferase, small subunit A 0.00471638
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 0.00470733
BGN biglycan 0.00470448
CEMIP cell migration inducing protein, hyaluronan binding 0.00470012
SMAGP small cell adhesion glycoprotein 0.00469257
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00468689
TGFB1 transforming growth factor, beta 1 0.00467508
ADIRF adipogenesis regulatory factor 0.00467063
DPYSL2 dihydropyrimidinase-like 2 0.00466194
S100A11 S100 calcium binding protein A11 0.00465017
SYNDIG1 synapse differentiation inducing 1 0.00463618
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00462341
TFF3 trefoil factor 3 (intestinal) 0.0046158
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 0.00461417
COL6A3 collagen, type VI, alpha 3 0.00460628
TNNT1 troponin T type 1 (skeletal, slow) 0.00459489
CD200 CD200 molecule 0.00459485
COLEC12 collectin sub-family member 12 0.00459186
PTS 6-pyruvoyltetrahydropterin synthase 0.00458173
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00457038
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 0.00456846
TLE2 transducin-like enhancer of split 2 0.00456387
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 0.00454236
CXCL12 chemokine (C-X-C motif) ligand 12 0.00453577
TRIM28 tripartite motif containing 28 0.00453426
MAPK13 mitogen-activated protein kinase 13 0.00453211
ATP5ME ATP synthase membrane subunit e 0.00452913
SPP1 secreted phosphoprotein 1 0.00452389
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.0045139
PFKL phosphofructokinase, liver 0.0045117
SLIRP SRA stem-loop interacting RNA binding protein 0.00451094
MRPS28 mitochondrial ribosomal protein S28 0.00450513
NUP210 nucleoporin 210kDa 0.00449964
LRRC15 leucine rich repeat containing 15 0.00449534
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.00448203
POLD2 polymerase (DNA directed), delta 2, accessory subunit 0.00446205
VAV3 vav 3 guanine nucleotide exchange factor 0.00445784
PHLDB1 pleckstrin homology-like domain, family B, member 1 0.00444491
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00444484
ATF1 activating transcription factor 1 0.00443108
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00442907
LXN latexin 0.00442853
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit 0.00442216
SOD3 superoxide dismutase 3, extracellular 0.00442013
MUC1 mucin 1, cell surface associated 0.00441697
MSRB2 methionine sulfoxide reductase B2 0.00441581
CAMP cathelicidin antimicrobial peptide 0.00440503
MXRA7 matrix-remodelling associated 7 0.00440464
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.0043982
CCNG2 cyclin G2 0.00439521
HMOX1 heme oxygenase 1 0.00438736
ARMCX1 armadillo repeat containing, X-linked 1 0.00438601
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.00437255
MT1E metallothionein 1E 0.0043718
ZNF93 zinc finger protein 93 0.0043656
KMT5B lysine methyltransferase 5B 0.00436191
SULF1 sulfatase 1 0.00436155
PCBP4 poly(rC) binding protein 4 0.00434351
TFAM transcription factor A, mitochondrial 0.00433685
CCNF cyclin F 0.00433181
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.00433093
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa 0.00432824
MOK MOK protein kinase 0.00432467
EGR1 early growth response 1 0.00432092
CSK c-src tyrosine kinase 0.00431648
RPS27L ribosomal protein S27-like 0.00431307
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 0.00431167
ATP5F1D ATP synthase F1 subunit delta 0.00429437
SST somatostatin 0.00428504
GLS glutaminase 0.00427788
REC8 REC8 meiotic recombination protein 0.00427372
COG2 component of oligomeric golgi complex 2 0.00426896
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 0.00425694
TRAPPC6A trafficking protein particle complex 6A 0.00425118
C9ORF3 chromosome 9 open reading frame 3 0.00424907
CLDN3 claudin 3 0.00424825
CENPT centromere protein T 0.0042472
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00422917
TMEM70 transmembrane protein 70 0.00422357
GPNMB glycoprotein (transmembrane) nmb 0.00421616
FHL1 four and a half LIM domains 1 0.00421119
KCTD12 potassium channel tetramerization domain containing 12 0.00420979
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 0.00420307
LGALS13 lectin, galactoside-binding, soluble, 13 0.00419897
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.00419684
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 0.00419546
GRSF1 G-rich RNA sequence binding factor 1 0.0041953
RCAN2 regulator of calcineurin 2 0.00418508
TRA2B transformer 2 beta homolog (Drosophila) 0.0041736
MFGE8 milk fat globule-EGF factor 8 protein 0.00417068
PFKM phosphofructokinase, muscle 0.00416446
ADIPOQ adiponectin, C1Q and collagen domain containing 0.00416393
ZWINT ZW10 interacting kinetochore protein 0.00416029
NEUROD1 neuronal differentiation 1 0.00415486
GPX7 glutathione peroxidase 7 0.00414176

decreased expression

Symbol Name Standardized Value
AQP3 aquaporin 3 (Gill blood group) -0.015224
E2F2 E2F transcription factor 2 -0.0115271
KRT5 keratin 5, type II -0.0104691
RGCC regulator of cell cycle -0.0103699
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.010323
CHPT1 choline phosphotransferase 1 -0.0101777
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00997857
XIC X chromosome inactivation center -0.00997138
KRT14 keratin 14, type I -0.00982541
SOX9 SRY (sex determining region Y)-box 9 -0.0098219
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00968847
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00945389
PDE4B phosphodiesterase 4B, cAMP-specific -0.00941349
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.0092973
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00896127
FGFR3 fibroblast growth factor receptor 3 -0.00886757
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00885591
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -0.00885425
ALCAM activated leukocyte cell adhesion molecule -0.00874796
DSC2 desmocollin 2 -0.00866305
HCRT hypocretin (orexin) neuropeptide precursor -0.00862972
DAXX death-domain associated protein -0.0085877
NTS neurotensin -0.00856947
KRT17 keratin 17, type I -0.008538
TUBB2A tubulin, beta 2A class IIa -0.00839304
GLUL glutamate-ammonia ligase -0.00827763
MAOB monoamine oxidase B -0.00827099
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00820635
BIRC3 baculoviral IAP repeat containing 3 -0.00819072
CSTA cystatin A (stefin A) -0.00811
LAMP3 lysosomal-associated membrane protein 3 -0.00805723
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00804833
TRIM29 tripartite motif containing 29 -0.00800093
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00798156
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.00797942
KRT13 keratin 13, type I -0.00796602
PI3 peptidase inhibitor 3, skin-derived -0.00794352
KRT15 keratin 15, type I -0.00793403
ALDOB aldolase B, fructose-bisphosphate -0.00792347
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.00780153
SPRR1B small proline-rich protein 1B -0.00779969
ABLIM1 actin binding LIM protein 1 -0.00778231
FOXG1 forkhead box G1 -0.00774371
CHN1 chimerin 1 -0.00772477
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0077055
ANXA1 annexin A1 -0.00768961
SDC2 syndecan 2 -0.00767503
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -0.00752033
F3 coagulation factor III (thromboplastin, tissue factor) -0.00747491
TAL1 T-cell acute lymphocytic leukemia 1 -0.00746437
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00743687
SIK1 salt-inducible kinase 1 -0.00738283
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00734113
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.00731601
DSG3 desmoglein 3 -0.00723853
COL4A5 collagen, type IV, alpha 5 -0.007232
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00716588
KRT1 keratin 1, type II -0.00715067
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00714989
GPC3 glypican 3 -0.00712225
TACSTD2 tumor-associated calcium signal transducer 2 -0.00711208
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -0.00705976
CD59 CD59 molecule, complement regulatory protein -0.00705328
ITGA6 integrin, alpha 6 -0.00704827
FABP7 fatty acid binding protein 7, brain -0.00700267
ARL4A ADP-ribosylation factor-like 4A -0.00699068
CXADR coxsackie virus and adenovirus receptor -0.00697308
CLU clusterin -0.00695026
VNN1 vanin 1 -0.00692729
CA2 carbonic anhydrase II -0.00691515
HNMT histamine N-methyltransferase -0.00677651
SFN stratifin -0.00675942
PRKCA protein kinase C, alpha -0.00674985
MYBPC1 myosin binding protein C, slow type -0.00674827
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.00671017
APOA2 apolipoprotein A-II -0.00669986
CCR7 chemokine (C-C motif) receptor 7 -0.00669518
RBM34 RNA binding motif protein 34 -0.006662
SYNM synemin, intermediate filament protein -0.00661742
PRAME preferentially expressed antigen in melanoma -0.00658693
CLCA4 chloride channel accessory 4 -0.0065576
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00652224
EDN3 endothelin 3 -0.00650193
IQCG IQ motif containing G -0.00648351
APOC3 apolipoprotein C-III -0.00647263
A2M alpha-2-macroglobulin -0.0064556
MSMB microseminoprotein, beta- -0.00644911
SARAF store-operated calcium entry-associated regulatory factor -0.0064216
LY6D lymphocyte antigen 6 complex, locus D -0.00640343
CANX calnexin -0.00638578
NEBL nebulette -0.00637139
SOD2 superoxide dismutase 2, mitochondrial -0.00632879
DLK1 delta-like 1 homolog (Drosophila) -0.00628338
SPRR3 small proline-rich protein 3 -0.00628212
TFR2 transferrin receptor 2 -0.00625866
FCGBP Fc fragment of IgG binding protein -0.00625844
LRRN3 leucine rich repeat neuronal 3 -0.0062375
KRT6A keratin 6A, type II -0.00620515
IKZF1 IKAROS family zinc finger 1 (Ikaros) -0.00618245
TREM1 triggering receptor expressed on myeloid cells 1 -0.00618172
CYBRD1 cytochrome b reductase 1 -0.00617771
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00611847
IGFBP1 insulin-like growth factor binding protein 1 -0.00609905
DLD dihydrolipoamide dehydrogenase -0.00603968
KRT6B keratin 6B, type II -0.00603844
OXA1L oxidase (cytochrome c) assembly 1-like -0.00602644
ANG angiogenin, ribonuclease, RNase A family, 5 -0.00601039
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.00600505
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -0.0059621
KRT81 keratin 81, type II -0.00595656
C1ORF115 chromosome 1 open reading frame 115 -0.00594239
ZNF750 zinc finger protein 750 -0.00592294
NKX3-1 NK3 homeobox 1 -0.00591837
COPA coatomer protein complex, subunit alpha -0.00590783
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00588825
WIF1 WNT inhibitory factor 1 -0.00587469
NIBAN1 niban apoptosis regulator 1 -0.00585009
TP63 tumor protein p63 -0.00581052
MTARC2 mitochondrial amidoxime reducing component 2 -0.00581027
RUNX3 runt-related transcription factor 3 -0.00578478
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00574272
SDC4 syndecan 4 -0.00573806
IRS2 insulin receptor substrate 2 -0.00573376
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.00573337
NES nestin -0.00571796
LYPD3 LY6/PLAUR domain containing 3 -0.00571786
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -0.00569234
TCTA T-cell leukemia translocation altered -0.00568477
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -0.0056532
STC1 stanniocalcin 1 -0.00561895
CHI3L2 chitinase 3-like 2 -0.0056169
APOB apolipoprotein B -0.00560571
CALML3 calmodulin-like 3 -0.00559944
C3 complement component 3 -0.00559469
WNK1 WNK lysine deficient protein kinase 1 -0.00559277
ARG1 arginase 1 -0.00556285
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 -0.00556181
CSRP2 cysteine and glycine-rich protein 2 -0.00552344
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -0.00552219
LY75 lymphocyte antigen 75 -0.00550706
S100A7 S100 calcium binding protein A7 -0.00550239
AQP9 aquaporin 9 -0.00549802
PIP prolactin-induced protein -0.00548698
STATH statherin -0.00547119
SPRR1A small proline-rich protein 1A -0.00543185
ISG20 interferon stimulated exonuclease gene 20kDa -0.00542823
CCN2 cellular communication network factor 2 -0.00539744
ITK IL2-inducible T-cell kinase -0.00537289
INHBB inhibin, beta B -0.00537237
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00536977
CFHR2 complement factor H-related 2 -0.00536832
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00536308
PER2 period circadian clock 2 -0.00534201
THBD thrombomodulin -0.0053044
STOM stomatin -0.00528555
APOC2 apolipoprotein C-II -0.00528381
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -0.00528061
TBX3 T-box 3 -0.00527525
CD52 CD52 molecule -0.00522719
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.0052123
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00521158
FGA fibrinogen alpha chain -0.00518926
SIX2 SIX homeobox 2 -0.00517799
KLHL2 kelch-like family member 2 -0.00515738
COBL cordon-bleu WH2 repeat protein -0.0051523
GPM6B glycoprotein M6B -0.00514707
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00514316
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -0.00513537
ZFP36L2 ZFP36 ring finger protein-like 2 -0.0051274
CXCL5 chemokine (C-X-C motif) ligand 5 -0.0051211
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -0.00511669
MMRN1 multimerin 1 -0.00508324
IDE insulin-degrading enzyme -0.00508209
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.00505744
EZR ezrin -0.00504895
GPM6A glycoprotein M6A -0.00504772
TSC22D1 TSC22 domain family, member 1 -0.00504764
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00503767
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.00503318
KAT7 K(lysine) acetyltransferase 7 -0.00503211
SNX13 sorting nexin 13 -0.00502548
IGSF3 immunoglobulin superfamily, member 3 -0.00502455
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00501965
GIMAP5 GTPase, IMAP family member 5 -0.0050064
HSPA4 heat shock 70kDa protein 4 -0.00500104
TM4SF4 transmembrane 4 L six family member 4 -0.00498613
CLDN8 claudin 8 -0.00498145
CLCA2 chloride channel accessory 2 -0.00494636
F5 coagulation factor V (proaccelerin, labile factor) -0.00494392
DSG1 desmoglein 1 -0.00493126
GSTA1 glutathione S-transferase alpha 1 -0.00492347
TMC5 transmembrane channel-like 5 -0.00492346
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 -0.00492154
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.00488851
MMP10 matrix metallopeptidase 10 -0.00488605
ANOS1 anosmin 1 -0.00488267
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 -0.00487335
CRELD2 cysteine-rich with EGF-like domains 2 -0.00485809
UQCRC2 ubiquinol-cytochrome c reductase core protein II -0.0048347
NGRN neugrin, neurite outgrowth associated -0.00482001
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.0048128
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00480897
PGAP3 post-GPI attachment to proteins 3 -0.0048036
XK X-linked Kx blood group -0.00479462
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.00479194
TRPS1 trichorhinophalangeal syndrome I -0.00478113
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00477381
AZIN1 antizyme inhibitor 1 -0.00476885
LRP4 low density lipoprotein receptor-related protein 4 -0.00476328
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -0.00476212
IL1RN interleukin 1 receptor antagonist -0.00475728
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.00475238
CD44 CD44 molecule (Indian blood group) -0.00475002
S100A2 S100 calcium binding protein A2 -0.00474736
CALCRL calcitonin receptor-like -0.00474058
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -0.00472967
PDZD8 PDZ domain containing 8 -0.0047185
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -0.00471215
COL21A1 collagen, type XXI, alpha 1 -0.00471067
UXT ubiquitously-expressed, prefoldin-like chaperone -0.00470662
COCH cochlin -0.00469718
ZNF395 zinc finger protein 395 -0.00469221
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00469114
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.0046705
AREG amphiregulin -0.0046656
AVPI1 arginine vasopressin-induced 1 -0.00466525
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00466152
EPAS1 endothelial PAS domain protein 1 -0.00466107
IL15RA interleukin 15 receptor, alpha -0.00466032
ORM1 orosomucoid 1 -0.00465903
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 -0.00465607
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) -0.00464744
APOH apolipoprotein H (beta-2-glycoprotein I) -0.00463268
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -0.00462608
NCOA4 nuclear receptor coactivator 4 -0.00462283
LCK LCK proto-oncogene, Src family tyrosine kinase -0.0046212
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.00461424
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00460339
C8ORF4 chromosome 8 open reading frame 4 -0.00460045
GYPC glycophorin C (Gerbich blood group) -0.00459918
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 -0.004599
PAH phenylalanine hydroxylase -0.0045955
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 -0.00459252
ELOVL5 ELOVL fatty acid elongase 5 -0.00458088
ZBTB16 zinc finger and BTB domain containing 16 -0.0045801
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.0045629
MXI1 MAX interactor 1, dimerization protein -0.00455815
LOR loricrin -0.0045382
PTGES prostaglandin E synthase -0.00453676
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00453382