BCL2 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description B-cell CLL/lymphoma 2|This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 596)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_BCL2
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Genes

220 co-expressed genes for BCL2 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AAK1 AP2 associated kinase 1
AANAT aralkylamine N-acetyltransferase
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADAM15 ADAM metallopeptidase domain 15
ADAMTSL2 ADAMTS-like 2
ADCY3 adenylate cyclase 3
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AFF2 AF4/FMR2 family, member 2
AGER advanced glycosylation end product-specific receptor
AGPS alkylglycerone phosphate synthase
ALDOC aldolase C, fructose-bisphosphate
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AQP5 aquaporin 5
AQP7 aquaporin 7
ARC activity-regulated cytoskeleton-associated protein
ARL3 ADP-ribosylation factor-like 3
ARSE arylsulfatase E (chondrodysplasia punctata 1)
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
ATRX alpha thalassemia/mental retardation syndrome X-linked
BAHD1 bromo adjacent homology domain containing 1
BCL2 B-cell CLL/lymphoma 2
BMP10 bone morphogenetic protein 10
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BPHL biphenyl hydrolase-like (serine hydrolase)
BRD1 bromodomain containing 1
C10ORF12 chromosome 10 open reading frame 12
C1ORF216 chromosome 1 open reading frame 216
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCKAR cholecystokinin A receptor
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD6 CD6 molecule
CD8B CD8b molecule
CDK13 cyclin-dependent kinase 13
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CEP135 centrosomal protein 135kDa
CLOCK clock circadian regulator
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CMA1 chymase 1, mast cell
CNTN2 contactin 2 (axonal)
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRCP CGRP receptor component
CRHR2 corticotropin releasing hormone receptor 2
CRYAA crystallin, alpha A
CTRL chymotrypsin-like
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DAPK2 death-associated protein kinase 2
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DKK4 dickkopf WNT signaling pathway inhibitor 4
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPT dermatopontin
DTNA dystrobrevin, alpha
DTX4 deltex 4, E3 ubiquitin ligase
ECE1 endothelin converting enzyme 1
ECE2 endothelin converting enzyme 2
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EPHB2 EPH receptor B2
ERC1 ELKS/RAB6-interacting/CAST family member 1
ESR1 estrogen receptor 1
ETV3 ets variant 3
EXTL3 exostosin-like glycosyltransferase 3
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAM189A2 family with sequence similarity 189, member A2
FANCG Fanconi anemia, complementation group G
FDXR ferredoxin reductase
FLT1 fms-related tyrosine kinase 1
FNTB farnesyltransferase, CAAX box, beta
FOSL1 FOS-like antigen 1
FRYL FRY-like
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GJB5 gap junction protein, beta 5, 31.1kDa
GLE1 GLE1 RNA export mediator
GPATCH8 G patch domain containing 8
GPR3 G protein-coupled receptor 3
GPR35 G protein-coupled receptor 35
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIP2 glutamate receptor interacting protein 2
GSTM5 glutathione S-transferase mu 5
GTSE1 G-2 and S-phase expressed 1
HAUS5 HAUS augmin-like complex, subunit 5
HOXD4 homeobox D4
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HSPB2 heat shock 27kDa protein 2
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL13 interleukin 13
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1
IPCEF1 interaction protein for cytohesin exchange factors 1
IRF2 interferon regulatory factor 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
IVL involucrin
JAG1 jagged 1
JAK3 Janus kinase 3
JRK Jrk homolog (mouse)
KANK2 KN motif and ankyrin repeat domains 2
KANK3 KN motif and ankyrin repeat domains 3
KAT8 K(lysine) acetyltransferase 8
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCTD20 potassium channel tetramerization domain containing 20
KIAA0195 KIAA0195
KIFC3 kinesin family member C3
KLHL18 kelch-like family member 18
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
KRT1 keratin 1, type II
KRT33A keratin 33A, type I
KRT86 keratin 86, type II
LBP lipopolysaccharide binding protein
LEFTY1 left-right determination factor 1
LMO1 LIM domain only 1 (rhombotin 1)
LOC166994 integral membrane glycoprotein-like
LRRC48 leucine rich repeat containing 48
LSM12 LSM12 homolog (S. cerevisiae)
LTBP4 latent transforming growth factor beta binding protein 4
LTK leukocyte receptor tyrosine kinase
LY9 lymphocyte antigen 9
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MC5R melanocortin 5 receptor
MGP matrix Gla protein
MLN motilin
MMP25 matrix metallopeptidase 25
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MR1 major histocompatibility complex, class I-related
MSL3 male-specific lethal 3 homolog (Drosophila)
MSX1 msh homeobox 1
MT4 metallothionein 4
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO9B myosin IXB
N4BP2L2 NEDD4 binding protein 2-like 2
NCKIPSD NCK interacting protein with SH3 domain
NEURL1 neuralized E3 ubiquitin protein ligase 1
NEUROD2 neuronal differentiation 2
NF1 neurofibromin 1
NFRKB nuclear factor related to kappaB binding protein
NOS2 nitric oxide synthase 2, inducible
NRP2 neuropilin 2
NRTN neurturin
NXPE3 neurexophilin and PC-esterase domain family, member 3
OPRL1 opiate receptor-like 1
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
PARVB parvin, beta
PAX7 paired box 7
PAX8 paired box 8
PAX9 paired box 9
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCBP3 poly(rC) binding protein 3
PCGF1 polycomb group ring finger 1
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIGR polymeric immunoglobulin receptor
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PML promyelocytic leukemia
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POU6F1 POU class 6 homeobox 1
POU6F2 POU class 6 homeobox 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRSS16 protease, serine, 16 (thymus)
PVT1 Pvt1 oncogene (non-protein coding)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBBP8 retinoblastoma binding protein 8
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RUNX1 runt-related transcription factor 1
SCAPER S-phase cyclin A-associated protein in the ER
SDC3 syndecan 3
SEZ6L seizure related 6 homolog (mouse)-like
SH2B1 SH2B adaptor protein 1
SIX3 SIX homeobox 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC22A24 solute carrier family 22, member 24
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SMYD5 SMYD family member 5
SPEF1 sperm flagellar 1
SSTR5 somatostatin receptor 5
STK17A serine/threonine kinase 17a
SULT4A1 sulfotransferase family 4A, member 1
SYT5 synaptotagmin V
TBC1D22A TBC1 domain family, member 22A
TBX19 T-box 19
TBX5 T-box 5
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TLN2 talin 2
TM4SF5 transmembrane 4 L six family member 5
TMEM11 transmembrane protein 11
TMPRSS6 transmembrane protease, serine 6
TMSB4Y thymosin beta 4, Y-linked
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TUBGCP4 tubulin, gamma complex associated protein 4
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UTRN utrophin
WDR62 WD repeat domain 62
WT1 Wilms tumor 1
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF292 zinc finger protein 292
ZNF500 zinc finger protein 500
ZNF592 zinc finger protein 592
ZNF710 zinc finger protein 710
ZP2 zona pellucida glycoprotein 2 (sperm receptor)