| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | BCL2-like 11 (apoptosis facilitator)|The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2013] (NCBI Entrez Gene Database, 10018) |
| External Link | https://ncbi.nlm.nih.gov/gene/10018 |
| Similar Terms | |
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499 genes differentially expressed following the BCL2L11 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.0289268 |
| LCN2 | lipocalin 2 | 0.0192301 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0174305 |
| CD9 | CD9 molecule | 0.0164666 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0156332 |
| KLK11 | kallikrein-related peptidase 11 | 0.0150679 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.0148209 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0142363 |
| KRT15 | keratin 15, type I | 0.0140401 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0139464 |
| IPO13 | importin 13 | 0.0136885 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.0135691 |
| HTRA1 | HtrA serine peptidase 1 | 0.0132802 |
| PEG10 | paternally expressed 10 | 0.0132352 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.0132218 |
| STC2 | stanniocalcin 2 | 0.0130803 |
| EGR2 | early growth response 2 | 0.0128217 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0125881 |
| S100A11 | S100 calcium binding protein A11 | 0.012388 |
| KLK10 | kallikrein-related peptidase 10 | 0.0120098 |
| MAL | mal, T-cell differentiation protein | 0.0119709 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.0117858 |
| ANXA11 | annexin A11 | 0.0117108 |
| PITX3 | paired-like homeodomain 3 | 0.011701 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.0116585 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0114696 |
| CRYAB | crystallin, alpha B | 0.0114332 |
| KRT19 | keratin 19, type I | 0.0113338 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.0112763 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | 0.011236 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.0110664 |
| ZNF395 | zinc finger protein 395 | 0.0110153 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0109929 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.010965 |
| BPGM | 2,3-bisphosphoglycerate mutase | 0.0108484 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0107259 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0107066 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | 0.0107025 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.0106014 |
| XIC | X chromosome inactivation center | 0.0105911 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0105842 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.0105756 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.010415 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.0103973 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0103535 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0102525 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0102272 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0102236 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0101828 |
| RAB5IF | RAB5 interacting factor | 0.0101784 |
| RGCC | regulator of cell cycle | 0.0101573 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0101478 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0101423 |
| WASHC4 | WASH complex subunit 4 | 0.0100663 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.0100421 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00997656 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00993781 |
| MVP | major vault protein | 0.00988634 |
| FOLR1 | folate receptor 1 (adult) | 0.00986989 |
| PTHLH | parathyroid hormone-like hormone | 0.00984451 |
| NRBF2 | nuclear receptor binding factor 2 | 0.00984276 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0098142 |
| OXTR | oxytocin receptor | 0.00981118 |
| IL1RN | interleukin 1 receptor antagonist | 0.00979736 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00972586 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00971204 |
| SPRR3 | small proline-rich protein 3 | 0.00959119 |
| PLBD1 | phospholipase B domain containing 1 | 0.00954812 |
| CALB1 | calbindin 1, 28kDa | 0.00953754 |
| EHD1 | EH-domain containing 1 | 0.00952162 |
| TCL1A | T-cell leukemia/lymphoma 1A | 0.0094761 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00945473 |
| NRIP3 | nuclear receptor interacting protein 3 | 0.00944264 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00943367 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00942593 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00938322 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00931955 |
| ECM1 | extracellular matrix protein 1 | 0.0093024 |
| PKM | pyruvate kinase, muscle | 0.00925186 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00923683 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 0.00920521 |
| CD7 | CD7 molecule | 0.00917888 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00915764 |
| SCEL | sciellin | 0.00912907 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.00910184 |
| DOK5 | docking protein 5 | 0.00908063 |
| INHBA | inhibin, beta A | 0.00907181 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00905965 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.00902215 |
| COG7 | component of oligomeric golgi complex 7 | 0.00900383 |
| AUTS2 | autism susceptibility candidate 2 | 0.00899478 |
| CTSD | cathepsin D | 0.00899461 |
| AOC1 | amine oxidase, copper containing 1 | 0.00898283 |
| DNTT | DNA nucleotidylexotransferase | 0.00898193 |
| CTSZ | cathepsin Z | 0.00897658 |
| VPREB1 | pre-B lymphocyte 1 | 0.00896422 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00892001 |
| GSDME | gasdermin E | 0.00891167 |
| IL1B | interleukin 1, beta | 0.00889776 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0088901 |
| EDN1 | endothelin 1 | 0.0088723 |
| ATF4 | activating transcription factor 4 | 0.00884025 |
| BST1 | bone marrow stromal cell antigen 1 | 0.00881228 |
| PFKP | phosphofructokinase, platelet | 0.00873117 |
| NPR3 | natriuretic peptide receptor 3 | 0.00872297 |
| PSEN1 | presenilin 1 | 0.00869338 |
| CD1B | CD1b molecule | 0.00864724 |
| CD79B | CD79b molecule, immunoglobulin-associated beta | 0.00860364 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00859173 |
| VNN1 | vanin 1 | 0.00858691 |
| WT1 | Wilms tumor 1 | 0.00851697 |
| CD22 | CD22 molecule | 0.00848023 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00847786 |
| PXDN | peroxidasin | 0.0084747 |
| CA12 | carbonic anhydrase XII | 0.0084548 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.00842663 |
| CCDC6 | coiled-coil domain containing 6 | 0.00841427 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00841356 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00836576 |
| FRMD4B | FERM domain containing 4B | 0.00836411 |
| LAT2 | linker for activation of T cells family, member 2 | 0.00833091 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.00831483 |
| SHROOM2 | shroom family member 2 | 0.00830521 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | 0.00830304 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00826866 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00825001 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.00824071 |
| PLIN3 | perilipin 3 | 0.00823562 |
| RGS20 | regulator of G-protein signaling 20 | 0.00823175 |
| FOXC1 | forkhead box C1 | 0.00820317 |
| HDAC9 | histone deacetylase 9 | 0.00819012 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00817264 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.00815988 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00814125 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00812847 |
| SLC16A4 | solute carrier family 16, member 4 | 0.0080978 |
| FST | follistatin | 0.00807719 |
| NYNRIN | NYN domain and retroviral integrase containing | 0.00805041 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.00804903 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00803562 |
| TALDO1 | transaldolase 1 | 0.00803212 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.00800653 |
| SQSTM1 | sequestosome 1 | 0.00799349 |
| GRN | granulin | 0.00798032 |
| TUFT1 | tuftelin 1 | 0.00795145 |
| LEFTY1 | left-right determination factor 1 | 0.00789526 |
| LAMB3 | laminin, beta 3 | 0.00789111 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00788995 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 0.00786947 |
| GPR137B | G protein-coupled receptor 137B | 0.00786526 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00786131 |
| LY96 | lymphocyte antigen 96 | 0.00785819 |
| CLDN10 | claudin 10 | 0.0078571 |
| TPM4 | tropomyosin 4 | 0.00784894 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00783947 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.00780401 |
| GM2A | GM2 ganglioside activator | 0.00779646 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 0.00778838 |
| RIT1 | Ras-like without CAAX 1 | 0.00777752 |
| RELA | v-rel avian reticuloendotheliosis viral oncogene homolog A | 0.0077651 |
| RABAC1 | Rab acceptor 1 (prenylated) | 0.00775771 |
| FOSL2 | FOS-like antigen 2 | 0.00774652 |
| TCP11L1 | t-complex 11, testis-specific-like 1 | 0.00771395 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 0.00771184 |
| LAMC2 | laminin, gamma 2 | 0.00770311 |
| S100A10 | S100 calcium binding protein A10 | 0.0076773 |
| MAP9 | microtubule-associated protein 9 | 0.00764131 |
| FAIM | Fas apoptotic inhibitory molecule | 0.00764039 |
| RAB25 | RAB25, member RAS oncogene family | 0.00760212 |
| KRT14 | keratin 14, type I | 0.00758499 |
| KRT13 | keratin 13, type I | 0.00751214 |
| GATA6 | GATA binding protein 6 | 0.00750939 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 0.00750284 |
| FOXG1 | forkhead box G1 | 0.00749437 |
| EFHD1 | EF-hand domain family, member D1 | 0.00748957 |
| VDAC2 | voltage-dependent anion channel 2 | 0.00745764 |
| GLDC | glycine dehydrogenase (decarboxylating) | 0.00742733 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.00741916 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00741647 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.00740412 |
| DEFB1 | defensin, beta 1 | 0.00738745 |
| NRG1 | neuregulin 1 | 0.00737842 |
| LASP1 | LIM and SH3 protein 1 | 0.00736472 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 | 0.00734988 |
| INAVA | innate immunity activator | 0.00734852 |
| KYNU | kynureninase | 0.00734206 |
| CLDN7 | claudin 7 | 0.0072997 |
| AICDA | activation-induced cytidine deaminase | 0.00729205 |
| TUBA4A | tubulin, alpha 4a | 0.00729008 |
| NREP | neuronal regeneration related protein | 0.00726616 |
| MGAM | maltase-glucoamylase | 0.00725629 |
| MICA | MHC class I polypeptide-related sequence A | 0.00725286 |
| PTK2B | protein tyrosine kinase 2 beta | 0.00724825 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00724129 |
| HK2 | hexokinase 2 | 0.00723656 |
| SERINC3 | serine incorporator 3 | 0.00721955 |
| THBS2 | thrombospondin 2 | 0.0072188 |
| NDP | Norrie disease (pseudoglioma) | 0.00720478 |
| HAL | histidine ammonia-lyase | 0.00719038 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 | 0.00718655 |
| SARS1 | seryl-tRNA synthetase 1 | 0.00718207 |
| CSNK2B | casein kinase 2, beta polypeptide | 0.00717442 |
| ATF3 | activating transcription factor 3 | 0.00713989 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.0071197 |
| NLRP2 | NLR family, pyrin domain containing 2 | 0.00711257 |
| GOLT1B | golgi transport 1B | 0.00711101 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00710171 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.00707265 |
| HOMER3 | homer scaffolding protein 3 | 0.0070599 |
| CLTB | clathrin, light chain B | 0.00705704 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.00704964 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.0070422 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00703626 |
| ARSJ | arylsulfatase family, member J | 0.00702806 |
| KRTAP1-1 | keratin associated protein 1-1 | 0.00702764 |
| STYXL1 | serine/threonine/tyrosine interacting-like 1 | 0.00702525 |
| PNMA8A | PNMA family member 8A | 0.00701171 |
| SGCE | sarcoglycan, epsilon | 0.00700733 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.00700548 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.00698602 |
| SPRR2B | small proline-rich protein 2B | 0.00697441 |
| TICAM1 | toll-like receptor adaptor molecule 1 | 0.0069604 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 0.00695147 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00693292 |
| RASAL2 | RAS protein activator like 2 | 0.00693033 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 0.0069198 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00690562 |
| SORT1 | sortilin 1 | 0.00689218 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00689019 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00688588 |
| ACVR2A | activin A receptor, type IIA | 0.00688176 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.00686466 |
| KL | klotho | 0.0068579 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.00685326 |
| AK4 | adenylate kinase 4 | 0.0068487 |
| CRIPT | cysteine-rich PDZ-binding protein | 0.00684111 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.00683559 |
| STX6 | syntaxin 6 | 0.00683435 |
| ARSL | arylsulfatase L | 0.00682966 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.00681439 |
| SIRPA | signal-regulatory protein alpha | 0.00680335 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00678456 |
| KIF1C | kinesin family member 1C | 0.00677968 |
| KLF10 | Kruppel-like factor 10 | 0.00677596 |
| IL33R | interleukin 33 receptor | 0.00677492 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.00676142 |
| ZPR1 | ZPR1 zinc finger | 0.00674987 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.00674756 |
| RTN3 | reticulon 3 | 0.00674414 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.00674347 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LYZ | lysozyme | -0.0225237 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0218117 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.0206157 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0198855 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0196421 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.0183674 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.017782 |
| PRDX2 | peroxiredoxin 2 | -0.0168155 |
| CA2 | carbonic anhydrase II | -0.0161807 |
| MGP | matrix Gla protein | -0.0158374 |
| DES | desmin | -0.015288 |
| LUM | lumican | -0.0152711 |
| NNMT | nicotinamide N-methyltransferase | -0.0152534 |
| HBB | hemoglobin, beta | -0.0151464 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.0148592 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0148426 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.014623 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0145056 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0143807 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.0143406 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0142115 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.0142056 |
| C1R | complement component 1, r subcomponent | -0.0141409 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0140661 |
| PLN | phospholamban | -0.0140525 |
| FGF13 | fibroblast growth factor 13 | -0.013865 |
| PDLIM3 | PDZ and LIM domain 3 | -0.0138152 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0137769 |
| TMSB15A | thymosin beta 15a | -0.0135429 |
| C1S | complement component 1, s subcomponent | -0.0134801 |
| COL15A1 | collagen, type XV, alpha 1 | -0.0131232 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | -0.0131095 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.0130744 |
| PTCH1 | patched 1 | -0.0130376 |
| RTN1 | reticulon 1 | -0.0130127 |
| C1QA | complement component 1, q subcomponent, A chain | -0.0129777 |
| SYNM | synemin, intermediate filament protein | -0.0129465 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.0129413 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.0129066 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.0127278 |
| TOM1L1 | target of myb1 (chicken)-like 1 | -0.0126299 |
| STK10 | serine/threonine kinase 10 | -0.0126142 |
| ELP1 | elongator acetyltransferase complex subunit 1 | -0.0125402 |
| FSTL1 | follistatin-like 1 | -0.0125191 |
| OLFM1 | olfactomedin 1 | -0.0125075 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.0124835 |
| RUFY3 | RUN and FYVE domain containing 3 | -0.0124186 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.0123638 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.0122504 |
| FGL2 | fibrinogen-like 2 | -0.0122375 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -0.0121655 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.0120886 |
| METRN | meteorin, glial cell differentiation regulator | -0.0120858 |
| TSPAN7 | tetraspanin 7 | -0.0120601 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0120523 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | -0.0119512 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.0118722 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0117305 |
| FZD6 | frizzled class receptor 6 | -0.0117228 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0116924 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0116626 |
| CALML5 | calmodulin-like 5 | -0.0116606 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0116181 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.0116174 |
| RGS1 | regulator of G-protein signaling 1 | -0.0114093 |
| REEP1 | receptor accessory protein 1 | -0.0113752 |
| LXN | latexin | -0.0112336 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.0112086 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.0111517 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0111154 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.0110351 |
| TNC | tenascin C | -0.0110054 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0109919 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.0109657 |
| PRR11 | proline rich 11 | -0.0108995 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0108893 |
| HHEX | hematopoietically expressed homeobox | -0.0108436 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0107491 |
| CHN1 | chimerin 1 | -0.0107398 |
| CDC20 | cell division cycle 20 | -0.0107092 |
| KIF20A | kinesin family member 20A | -0.0106704 |
| PRC1 | protein regulator of cytokinesis 1 | -0.0106533 |
| GOLM1 | golgi membrane protein 1 | -0.0106055 |
| HOXC6 | homeobox C6 | -0.0105931 |
| SFN | stratifin | -0.0105373 |
| HELLS | helicase, lymphoid-specific | -0.010536 |
| TSPAN13 | tetraspanin 13 | -0.0104921 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.0104559 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.0104485 |
| HSPB8 | heat shock 22kDa protein 8 | -0.0104422 |
| PLEK | pleckstrin | -0.0104291 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.0104181 |
| METTL7A | methyltransferase like 7A | -0.0103897 |
| FRZB | frizzled-related protein | -0.0103867 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0103094 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.0102982 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.0102571 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0100735 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.010062 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.0100463 |
| ASPN | asporin | -0.00996213 |
| TXLNA | taxilin alpha | -0.0099345 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00993238 |
| SDC3 | syndecan 3 | -0.00988731 |
| CFD | complement factor D (adipsin) | -0.00988314 |
| IL10RA | interleukin 10 receptor, alpha | -0.00987854 |
| FAM46C | family with sequence similarity 46, member C | -0.0098365 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00983128 |
| PRKCB | protein kinase C, beta | -0.00983105 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -0.00983075 |
| ZNF721 | zinc finger protein 721 | -0.00982197 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00979475 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | -0.00979194 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00976986 |
| FHL1 | four and a half LIM domains 1 | -0.00976009 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00973635 |
| PCLAF | PCNA clamp associated factor | -0.00971238 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.00971219 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | -0.00967469 |
| GCH1 | GTP cyclohydrolase 1 | -0.00962409 |
| DCLK1 | doublecortin-like kinase 1 | -0.0095629 |
| CHRDL1 | chordin-like 1 | -0.0095512 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00948407 |
| SEPTIN10 | septin 10 | -0.00947883 |
| DUT | deoxyuridine triphosphatase | -0.00946661 |
| TPBG | trophoblast glycoprotein | -0.00940184 |
| IRF8 | interferon regulatory factor 8 | -0.00939935 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00938953 |
| A2M | alpha-2-macroglobulin | -0.00936375 |
| RGS5 | regulator of G-protein signaling 5 | -0.00933936 |
| BEX1 | brain expressed, X-linked 1 | -0.0092962 |
| PPA2 | pyrophosphatase (inorganic) 2 | -0.00927852 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00925088 |
| CCND1 | cyclin D1 | -0.00923737 |
| TXNIP | thioredoxin interacting protein | -0.00922749 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | -0.00922649 |
| TFF1 | trefoil factor 1 | -0.00917563 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00916891 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.00916849 |
| RAPSN | receptor-associated protein of the synapse | -0.00910973 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00909283 |
| NFIB | nuclear factor I/B | -0.00906477 |
| SMTN | smoothelin | -0.00906144 |
| AADAC | arylacetamide deacetylase | -0.00905818 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | -0.00900482 |
| RCAN2 | regulator of calcineurin 2 | -0.008993 |
| STOM | stomatin | -0.0089906 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00898725 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.00896137 |
| FOXF1 | forkhead box F1 | -0.00895944 |
| LONP2 | lon peptidase 2, peroxisomal | -0.00894539 |
| OPHN1 | oligophrenin 1 | -0.00894379 |
| LAMA4 | laminin, alpha 4 | -0.00889934 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00889917 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00887886 |
| HLA-DOB | major histocompatibility complex, class II, DO beta | -0.00886288 |
| BMP4 | bone morphogenetic protein 4 | -0.00886023 |
| MERTK | MER proto-oncogene, tyrosine kinase | -0.00883312 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.00882206 |
| DLD | dihydrolipoamide dehydrogenase | -0.00880684 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 | -0.00878711 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.00876228 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00875319 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00874682 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.00873109 |
| RPL10 | ribosomal protein L10 | -0.00872465 |
| INSR | insulin receptor | -0.0087032 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.0086932 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00866568 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00863267 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00860683 |
| OIP5 | Opa interacting protein 5 | -0.00856737 |
| TMEM176B | transmembrane protein 176B | -0.00855549 |
| GPM6B | glycoprotein M6B | -0.00855451 |
| PMP22 | peripheral myelin protein 22 | -0.00853753 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.0085045 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -0.00847327 |
| DST | dystonin | -0.00846284 |
| DPT | dermatopontin | -0.00845949 |
| SLC2A4RG | SLC2A4 regulator | -0.00845105 |
| CNN3 | calponin 3, acidic | -0.0084473 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0084284 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.00838083 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.00834574 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00831033 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00826898 |
| ITGA7 | integrin, alpha 7 | -0.00823871 |
| CHGA | chromogranin A | -0.00823682 |
| MELK | maternal embryonic leucine zipper kinase | -0.00822329 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0082205 |
| TBX3 | T-box 3 | -0.008184 |
| ISCA1 | iron-sulfur cluster assembly 1 | -0.00817695 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | -0.00817632 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00816636 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | -0.0081158 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00809779 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00809607 |
| CD163 | CD163 molecule | -0.00808067 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00807526 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00803741 |
| FBLN2 | fibulin 2 | -0.00802982 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | -0.0080161 |
| H1-0 | H1.0 linker histone | -0.00800011 |
| CLU | clusterin | -0.00799738 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa | -0.00798737 |
| CCR2 | chemokine (C-C motif) receptor 2 | -0.00793868 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00793479 |
| NPTX2 | neuronal pentraxin II | -0.00792329 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00791495 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.00791415 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 | -0.00787533 |
| HOXA5 | homeobox A5 | -0.00786443 |
| NTS | neurotensin | -0.00785843 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00785561 |
| PROM1 | prominin 1 | -0.00783108 |
| RUFY2 | RUN and FYVE domain containing 2 | -0.00780153 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00778921 |
| MGST2 | microsomal glutathione S-transferase 2 | -0.00778657 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.00778508 |
| NAE1 | NEDD8 activating enzyme E1 subunit 1 | -0.00778084 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00777598 |
| DIO2 | deiodinase, iodothyronine, type II | -0.00777593 |
| MSX1 | msh homeobox 1 | -0.00774836 |
| ZNF160 | zinc finger protein 160 | -0.00774253 |
| GLTP | glycolipid transfer protein | -0.00773819 |
| FANCI | Fanconi anemia, complementation group I | -0.0077177 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | -0.00767623 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00767322 |
| ECI1 | enoyl-CoA delta isomerase 1 | -0.00766851 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | -0.00763226 |
| ACKR3 | atypical chemokine receptor 3 | -0.00762587 |
| TFR2 | transferrin receptor 2 | -0.00760118 |
| RASA4 | RAS p21 protein activator 4 | -0.00758504 |
| CCL21 | chemokine (C-C motif) ligand 21 | -0.00757661 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | -0.00757101 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 | -0.00756065 |
| NID1 | nidogen 1 | -0.00754253 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00753303 |
| NAAA | N-acylethanolamine acid amidase | -0.00753217 |
| GAS1 | growth arrest-specific 1 | -0.00752677 |
| KHK | ketohexokinase (fructokinase) | -0.00752624 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 | -0.00751966 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00751761 |
| CLIC2 | chloride intracellular channel 2 | -0.00749805 |
| RELN | reelin | -0.00749223 |
| ITGA6 | integrin, alpha 6 | -0.00747689 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00746714 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | -0.00745539 |
| CES3 | carboxylesterase 3 | -0.00744491 |
