BCL2L11 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description BCL2-like 11 (apoptosis facilitator)|The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2013] (NCBI Entrez Gene Database, 10018)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_BCL2L11
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Genes

187 co-expressed genes for BCL2L11 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADAM20 ADAM metallopeptidase domain 20
ADAMTSL3 ADAMTS-like 3
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
AMOT angiomotin
AOC4P amine oxidase, copper containing 4, pseudogene
AQP7 aquaporin 7
ARL3 ADP-ribosylation factor-like 3
ATF2 activating transcription factor 2
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP4B ATPase, H+/K+ exchanging, beta polypeptide
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATXN3 ataxin 3
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BMP10 bone morphogenetic protein 10
BRCA1 breast cancer 1, early onset
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C1ORF216 chromosome 1 open reading frame 216
CADM4 cell adhesion molecule 4
CALN1 calneuron 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCL16 chemokine (C-C motif) ligand 16
CCR3 chemokine (C-C motif) receptor 3
CD8A CD8a molecule
CDC73 cell division cycle 73
CEP162 centrosomal protein 162kDa
CFH complement factor H
COL19A1 collagen, type XIX, alpha 1
COL8A1 collagen, type VIII, alpha 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPB2 carboxypeptidase B2 (plasma)
CRHR1 corticotropin releasing hormone receptor 1
CTRL chymotrypsin-like
CXCL5 chemokine (C-X-C motif) ligand 5
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DBT dihydrolipoamide branched chain transacylase E2
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DKFZP434C153 DKFZP434C153 protein
DMD dystrophin
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EPHB2 EPH receptor B2
ERCC4 excision repair cross-complementation group 4
EXOC4 exocyst complex component 4
F2RL3 coagulation factor II (thrombin) receptor-like 3
FAM153B family with sequence similarity 153, member B
FAS Fas cell surface death receptor
FBXL4 F-box and leucine-rich repeat protein 4
FGF18 fibroblast growth factor 18
FNTB farnesyltransferase, CAAX box, beta
FOSL1 FOS-like antigen 1
FSHR follicle stimulating hormone receptor
FZD5 frizzled class receptor 5
GCM1 glial cells missing homolog 1 (Drosophila)
GJB5 gap junction protein, beta 5, 31.1kDa
GLE1 GLE1 RNA export mediator
GLRA3 glycine receptor, alpha 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNPAT glyceronephosphate O-acyltransferase
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR171 G protein-coupled receptor 171
GPR18 G protein-coupled receptor 18
GPR19 G protein-coupled receptor 19
GUCY2C guanylate cyclase 2C
GUCY2F guanylate cyclase 2F, retinal
HCG8 HLA complex group 8
HCRTR2 hypocretin (orexin) receptor 2
HIST1H3E histone cluster 1, H3e
HNF1A HNF1 homeobox A
HOXD4 homeobox D4
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFNA14 interferon, alpha 14
IGKV7-3 immunoglobulin kappa variable 7-3 (pseudogene)
IL11RA interleukin 11 receptor, alpha
IL16 interleukin 16
IL7 interleukin 7
IPO9 importin 9
IVL involucrin
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KNG1 kininogen 1
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
KRT2 keratin 2, type II
KRT33A keratin 33A, type I
KRT34 keratin 34, type I
LECT2 leukocyte cell-derived chemotaxin 2
LGI1 leucine-rich, glioma inactivated 1
LOR loricrin
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRC48 leucine rich repeat containing 48
LTBP4 latent transforming growth factor beta binding protein 4
MAGEA9 melanoma antigen family A9
MAP2 microtubule-associated protein 2
MASP2 mannan-binding lectin serine peptidase 2
MC5R melanocortin 5 receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MON2 MON2 homolog (S. cerevisiae)
MSL3 male-specific lethal 3 homolog (Drosophila)
MYH2 myosin, heavy chain 2, skeletal muscle, adult
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NOS2 nitric oxide synthase 2, inducible
NPFF neuropeptide FF-amide peptide precursor
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRTN neurturin
NRXN1 neurexin 1
NTNG2 netrin G2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OCM oncomodulin
OR2B6 olfactory receptor, family 2, subfamily B, member 6
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PAX7 paired box 7
PAX9 paired box 9
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCDHB17P protocadherin beta 17 pseudogene
PCM1 pericentriolar material 1
PDE10A phosphodiesterase 10A
PDE4D phosphodiesterase 4D, cAMP-specific
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
PGM3 phosphoglucomutase 3
PHF10 PHD finger protein 10
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHOX2B paired-like homeobox 2b
PLA2R1 phospholipase A2 receptor 1, 180kDa
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POU6F1 POU class 6 homeobox 1
POU6F2 POU class 6 homeobox 2
PSG1 pregnancy specific beta-1-glycoprotein 1
PTPRB protein tyrosine phosphatase, receptor type, B
PVR poliovirus receptor
R3HCC1L R3H domain and coiled-coil containing 1-like
RAD51D RAD51 paralog D
RB1CC1 RB1-inducible coiled-coil 1
RNF24 ring finger protein 24
RORB RAR-related orphan receptor B
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RREB1 ras responsive element binding protein 1
RUNX2 runt-related transcription factor 2
RXRG retinoid X receptor, gamma
RYR3 ryanodine receptor 3
S100A5 S100 calcium binding protein A5
SCN7A sodium channel, voltage gated, type VII alpha subunit
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SIM2 single-minded family bHLH transcription factor 2
SIRPB1 signal-regulatory protein beta 1
SIX6 SIX homeobox 6
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC17A3 solute carrier family 17 (organic anion transporter), member 3
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SOAT2 sterol O-acyltransferase 2
SPA17 sperm autoantigenic protein 17
SPAG11B sperm associated antigen 11B
SPATA2 spermatogenesis associated 2
SRPK3 SRSF protein kinase 3
STAC SH3 and cysteine rich domain
SULT4A1 sulfotransferase family 4A, member 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SYT5 synaptotagmin V
T T, brachyury homolog (mouse)
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBX19 T-box 19
TENM4 teneurin transmembrane protein 4
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TMEM26 transmembrane protein 26
TRIM24 tripartite motif containing 24
TSSK2 testis-specific serine kinase 2
TTTY1 testis-specific transcript, Y-linked 1 (non-protein coding)
USP46 ubiquitin specific peptidase 46
ZBTB14 zinc finger and BTB domain containing 14
ZNF134 zinc finger protein 134
ZNF157 zinc finger protein 157
ZNF200 zinc finger protein 200
ZNF266 zinc finger protein 266
ZNF821 zinc finger protein 821
ZP2 zona pellucida glycoprotein 2 (sperm receptor)
ZSCAN26 zinc finger and SCAN domain containing 26