BCL3 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description B-cell CLL/lymphoma 3|This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 602)
External Link https://ncbi.nlm.nih.gov/gene/602
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Genes

500 genes differentially expressed following the BCL3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CA2 carbonic anhydrase II 0.0169004
MAP7 microtubule-associated protein 7 0.0163091
PRDX2 peroxiredoxin 2 0.0152338
CRIP2 cysteine-rich protein 2 0.0125302
SPRED2 sprouty-related, EVH1 domain containing 2 0.0125022
RPA3 replication protein A3, 14kDa 0.0118578
SELENOT selenoprotein T 0.0115775
TNC tenascin C 0.0111706
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0111592
GET1 guided entry of tail-anchored proteins factor 1 0.0110991
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.0107449
HOXC6 homeobox C6 0.0103422
ANKRD10 ankyrin repeat domain 10 0.0101429
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.00990038
TMEM126B transmembrane protein 126B 0.00983572
SDC2 syndecan 2 0.00979155
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.00978928
ASPH aspartate beta-hydroxylase 0.00971953
SRSF1 serine/arginine-rich splicing factor 1 0.00970165
CGRRF1 cell growth regulator with ring finger domain 1 0.00960228
PCLAF PCNA clamp associated factor 0.00954958
CXCL9 chemokine (C-X-C motif) ligand 9 0.00951992
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 0.00950382
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00947614
FASN fatty acid synthase 0.00947237
TRAM1 translocation associated membrane protein 1 0.00942282
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.0093728
PHACTR2 phosphatase and actin regulator 2 0.00925918
RSL24D1 ribosomal L24 domain containing 1 0.00916693
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.00916035
RAB20 RAB20, member RAS oncogene family 0.00915853
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.00903485
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00893309
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00890778
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.00890074
NRGN neurogranin (protein kinase C substrate, RC3) 0.00887379
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00878637
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00871424
CKS2 CDC28 protein kinase regulatory subunit 2 0.00867161
TMEM70 transmembrane protein 70 0.00865171
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00863694
KIF14 kinesin family member 14 0.00857054
CTSZ cathepsin Z 0.00839721
CCR2 chemokine (C-C motif) receptor 2 0.00839501
AKR1C3 aldo-keto reductase family 1, member C3 0.00833505
CST3 cystatin C 0.00831322
RXRA retinoid X receptor, alpha 0.00817343
SPTSSA serine palmitoyltransferase, small subunit A 0.00816764
CPVL carboxypeptidase, vitellogenic-like 0.00813927
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00803342
METTL7A methyltransferase like 7A 0.00793653
SRSF10 serine/arginine-rich splicing factor 10 0.00793334
GLUL glutamate-ammonia ligase 0.00784728
HSPA14 heat shock 70kDa protein 14 0.00783758
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 0.00782605
OIP5 Opa interacting protein 5 0.00781597
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00781112
FGL2 fibrinogen-like 2 0.00778843
PBK PDZ binding kinase 0.00778596
RWDD1 RWD domain containing 1 0.00776841
SC5D sterol-C5-desaturase 0.00776193
DSE dermatan sulfate epimerase 0.00775061
IL6ST interleukin 6 signal transducer 0.00769869
CDC42 cell division cycle 42 0.00769026
SLC38A1 solute carrier family 38, member 1 0.00768703
LST1 leukocyte specific transcript 1 0.00768567
HMGB1 high mobility group box 1 0.0076262
TSPAN6 tetraspanin 6 0.00761317
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 0.00761261
ANXA5 annexin A5 0.0076116
NNMT nicotinamide N-methyltransferase 0.00759518
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.0075886
SHMT1 serine hydroxymethyltransferase 1 (soluble) 0.00758195
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00752099
PLAAT3 phospholipase A and acyltransferase 3 0.0075189
PEX3 peroxisomal biogenesis factor 3 0.00751351
TFDP1 transcription factor Dp-1 0.00748551
SREBF1 sterol regulatory element binding transcription factor 1 0.00745618
CDKN3 cyclin-dependent kinase inhibitor 3 0.00742536
S100A4 S100 calcium binding protein A4 0.00740598
MRPL42 mitochondrial ribosomal protein L42 0.00740007
CRLF1 cytokine receptor-like factor 1 0.00739212
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.007391
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 0.00738271
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.00737521
RNF130 ring finger protein 130 0.00737045
EMP3 epithelial membrane protein 3 0.00737024
INSIG1 insulin induced gene 1 0.00735689
IRX5 iroquois homeobox 5 0.00733009
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 0.00731481
RAPSN receptor-associated protein of the synapse 0.0073068
HOXB6 homeobox B6 0.00727011
H1-0 H1.0 linker histone 0.00725133
CSK c-src tyrosine kinase 0.00724553
GTF2A2 general transcription factor IIA, 2, 12kDa 0.0072181
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00721415
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.00719741
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.00717421
ARMT1 acidic residue methyltransferase 1 0.00717305
YME1L1 YME1-like 1 ATPase 0.00717227
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 0.00715767
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00715266
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00715125
ACAT2 acetyl-CoA acetyltransferase 2 0.00714763
FKBP5 FK506 binding protein 5 0.00714506
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0071306
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase 0.00710501
CD99 CD99 molecule 0.00709932
UBE2S ubiquitin-conjugating enzyme E2S 0.00708688
ATF1 activating transcription factor 1 0.00706623
PRC1 protein regulator of cytokinesis 1 0.00706336
CCNE2 cyclin E2 0.00704657
MTA1 metastasis associated 1 0.00704207
VBP1 von Hippel-Lindau binding protein 1 0.00703064
PPA2 pyrophosphatase (inorganic) 2 0.0070206
RAB4A RAB4A, member RAS oncogene family 0.00701509
SRSF7 serine/arginine-rich splicing factor 7 0.00699751
CREBZF CREB/ATF bZIP transcription factor 0.00697826
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00695214
NOTCH2 notch 2 0.00694351
CRLF3 cytokine receptor-like factor 3 0.00692981
XPO7 exportin 7 0.00691962
RAD51C RAD51 paralog C 0.00691168
CDC20 cell division cycle 20 0.00690798
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.00689501
SFRP4 secreted frizzled-related protein 4 0.00688848
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00688797
ZBTB18 zinc finger and BTB domain containing 18 0.00683416
SUMO3 small ubiquitin-like modifier 3 0.00683123
NPM3 nucleophosmin/nucleoplasmin 3 0.0068009
MDFIC MyoD family inhibitor domain containing 0.00679189
TXNDC9 thioredoxin domain containing 9 0.00675203
SEPTIN10 septin 10 0.00673167
DCXR dicarbonyl/L-xylulose reductase 0.00672776
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.0067264
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.00672538
COMMD10 COMM domain containing 10 0.00672138
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.00670467
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00668999
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 0.00668562
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.00667863
THAP11 THAP domain containing 11 0.0066741
PLIN1 perilipin 1 0.00666416
TNS3 tensin 3 0.00666402
CCL19 chemokine (C-C motif) ligand 19 0.00664134
GAMT guanidinoacetate N-methyltransferase 0.006639
IRF8 interferon regulatory factor 8 0.00663809
SNRPG small nuclear ribonucleoprotein polypeptide G 0.00663577
LGALS1 lectin, galactoside-binding, soluble, 1 0.00663372
TXNIP thioredoxin interacting protein 0.00663222
E2F8 E2F transcription factor 8 0.0066241
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00661765
MRPS30 mitochondrial ribosomal protein S30 0.00660093
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 0.00659302
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.0065619
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.00655233
HMGB3 high mobility group box 3 0.00653949
TM7SF2 transmembrane 7 superfamily member 2 0.00653934
CLEC10A C-type lectin domain family 10, member A 0.00653136
ENY2 enhancer of yellow 2 homolog (Drosophila) 0.00651598
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.00650515
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.00649853
HEBP2 heme binding protein 2 0.0064803
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00645435
GPN3 GPN-loop GTPase 3 0.00644191
TPRKB TP53RK binding protein 0.0064347
ATAD2 ATPase family, AAA domain containing 2 0.0064339
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.00642917
LTBP2 latent transforming growth factor beta binding protein 2 0.0064277
CENPX centromere protein X 0.00642334
NINJ2 ninjurin 2 0.00642276
MED28 mediator complex subunit 28 0.00640889
TMCO3 transmembrane and coiled-coil domains 3 0.0063862
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 0.0063831
PFKL phosphofructokinase, liver 0.00635737
ATP5MG ATP synthase membrane subunit g 0.00634614
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.0063418
MACROH2A1 macroH2A.1 histone 0.0063331
GLA galactosidase, alpha 0.00632857
CLDND1 claudin domain containing 1 0.00632269
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.00630924
APOA1 apolipoprotein A-I 0.0063012
GTPBP8 GTP-binding protein 8 (putative) 0.00628877
ACTB actin, beta 0.00627766
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.00627531
FADS1 fatty acid desaturase 1 0.00626033
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 0.00625834
ALDOA aldolase A, fructose-bisphosphate 0.00625519
NNT nicotinamide nucleotide transhydrogenase 0.00624728
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.00624479
RAB25 RAB25, member RAS oncogene family 0.00624426
MELK maternal embryonic leucine zipper kinase 0.00621195
APOA2 apolipoprotein A-II 0.00620628
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00615589
GCHFR GTP cyclohydrolase I feedback regulator 0.00614471
MOCS2 molybdenum cofactor synthesis 2 0.00612881
GUSBP3 glucuronidase, beta pseudogene 3 0.00610224
SPC25 SPC25, NDC80 kinetochore complex component 0.00609957
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) 0.00609392
METTL5 methyltransferase like 5 0.00609217
FANCI Fanconi anemia, complementation group I 0.00607129
CPB1 carboxypeptidase B1 (tissue) 0.00601177
CD164 CD164 molecule, sialomucin 0.00600995
LYZ lysozyme 0.00600967
CCDC92 coiled-coil domain containing 92 0.00600516
BEX1 brain expressed, X-linked 1 0.0060021
ZNF207 zinc finger protein 207 0.00600028
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00599596
CCNA2 cyclin A2 0.00598866
SNX7 sorting nexin 7 0.00596523
PTS 6-pyruvoyltetrahydropterin synthase 0.00596512
LMNB2 lamin B2 0.00595761
GPC1 glypican 1 0.00594137
TMX1 thioredoxin-related transmembrane protein 1 0.00593133
PSD3 pleckstrin and Sec7 domain containing 3 0.00593066
CD9 CD9 molecule 0.00592684
GDE1 glycerophosphodiester phosphodiesterase 1 0.00592474
TMEM14A transmembrane protein 14A 0.00592473
BCL7B B-cell CLL/lymphoma 7B 0.0059138
H2AX H2A.X variant histone 0.00591067
PRKCB protein kinase C, beta 0.00589612
TMEM38B transmembrane protein 38B 0.00588036
TOX3 TOX high mobility group box family member 3 0.0058749
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 0.0058707
MAN1A2 mannosidase, alpha, class 1A, member 2 0.00586167
HNRNPF heterogeneous nuclear ribonucleoprotein F 0.00585936
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.0058581
DLG1 discs, large homolog 1 (Drosophila) 0.00584171
YIPF5 Yip1 domain family, member 5 0.00583841
AKR1C1 aldo-keto reductase family 1, member C1 0.00583518
DHFR dihydrofolate reductase 0.00581851
HELLS helicase, lymphoid-specific 0.00581104
ESR1 estrogen receptor 1 0.00580285
ECHDC1 ethylmalonyl-CoA decarboxylase 1 0.00579822
MAP2K1 mitogen-activated protein kinase kinase 1 0.00577903
MRPS28 mitochondrial ribosomal protein S28 0.0057628
LOXL1 lysyl oxidase-like 1 0.00575579
LDOC1 leucine zipper, down-regulated in cancer 1 0.00575288
COL10A1 collagen, type X, alpha 1 0.0057404
CEP43 centrosomal protein 43 0.00572574
RABL6 RAB, member RAS oncogene family-like 6 0.00571057
ZNF124 zinc finger protein 124 0.0056905
RHOA ras homolog family member A 0.00568419
LEPR leptin receptor 0.00567587
NBPF10 neuroblastoma breakpoint family, member 10 0.00567342
HIP1 huntingtin interacting protein 1 0.00566361
APIP APAF1 interacting protein 0.00565549
UBL4A ubiquitin-like 4A 0.00565466
PPARG peroxisome proliferator-activated receptor gamma 0.00565043
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.00564856

decreased expression

Symbol Name Standardized Value
IFI27 interferon, alpha-inducible protein 27 -0.0250557
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0187472
S100P S100 calcium binding protein P -0.0166589
LCN2 lipocalin 2 -0.0160353
TCTA T-cell leukemia translocation altered -0.0153479
PRAME preferentially expressed antigen in melanoma -0.0152935
KRT15 keratin 15, type I -0.0152852
ATF3 activating transcription factor 3 -0.015126
HSPA1A heat shock 70kDa protein 1A -0.0150173
DLK1 delta-like 1 homolog (Drosophila) -0.0146802
KRT5 keratin 5, type II -0.0145963
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.0143582
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0138621
KRT14 keratin 14, type I -0.013783
FXYD3 FXYD domain containing ion transport regulator 3 -0.0125768
KLK10 kallikrein-related peptidase 10 -0.0124297
CRABP1 cellular retinoic acid binding protein 1 -0.0122677
KRT6A keratin 6A, type II -0.0122164
SLPI secretory leukocyte peptidase inhibitor -0.01219
ASS1 argininosuccinate synthase 1 -0.0120124
USP18 ubiquitin specific peptidase 18 -0.0120042
MMP7 matrix metallopeptidase 7 -0.012002
PDZK1IP1 PDZK1 interacting protein 1 -0.0119553
MX1 MX dynamin-like GTPase 1 -0.0118234
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0115581
LAMP3 lysosomal-associated membrane protein 3 -0.0115161
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0114831
KLK11 kallikrein-related peptidase 11 -0.0114795
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.011478
IFI6 interferon, alpha-inducible protein 6 -0.0114163
TUBB2A tubulin, beta 2A class IIa -0.0114095
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.0114046
JCHAIN joining chain of multimeric IgA and IgM -0.0113293
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0111536
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.0111349
GALC galactosylceramidase -0.0110669
AKAP12 A kinase (PRKA) anchor protein 12 -0.0110459
COG7 component of oligomeric golgi complex 7 -0.0109768
AHNAK2 AHNAK nucleoprotein 2 -0.0109051
RRAGD Ras-related GTP binding D -0.0108972
KRT13 keratin 13, type I -0.0108891
HIST1H2BD histone cluster 1, H2bd -0.0108254
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.0107387
FCGBP Fc fragment of IgG binding protein -0.0106899
SRPX sushi-repeat containing protein, X-linked -0.0106893
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.0106252
TARP TCR gamma alternate reading frame protein -0.0105493
SCGB2A1 secretoglobin, family 2A, member 1 -0.0104906
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.0104172
CCN2 cellular communication network factor 2 -0.0103607
IL1RN interleukin 1 receptor antagonist -0.0103147
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.010174
S100A7 S100 calcium binding protein A7 -0.0101594
GOLGA8H golgin A8 family, member H -0.0100855
CAPN3 calpain 3, (p94) -0.00999369
CD69 CD69 molecule -0.00996699
XIC X chromosome inactivation center -0.00996045
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.0099181
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.00987141
IFI44 interferon-induced protein 44 -0.00986199
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00979697
PI3 peptidase inhibitor 3, skin-derived -0.00974077
AQP3 aquaporin 3 (Gill blood group) -0.00973822
CCL20 chemokine (C-C motif) ligand 20 -0.00967839
STAB1 stabilin 1 -0.00963747
PKP1 plakophilin 1 -0.00961557
TACSTD2 tumor-associated calcium signal transducer 2 -0.00959595
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.00955054
CD93 CD93 molecule -0.00948986
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00941552
DAXX death-domain associated protein -0.00941209
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.0093879
IFI35 interferon-induced protein 35 -0.00938264
HSPB1 heat shock 27kDa protein 1 -0.00931344
EGFL6 EGF-like-domain, multiple 6 -0.00906511
VWF von Willebrand factor -0.00904638
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.00898044
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00892726
IFI44L interferon-induced protein 44-like -0.00890594
ISG20 interferon stimulated exonuclease gene 20kDa -0.00887281
PTHLH parathyroid hormone-like hormone -0.00883348
WARS1 tryptophanyl-tRNA synthetase 1 -0.0088203
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00881142
TUBB2B tubulin, beta 2B class IIb -0.00881074
TOX thymocyte selection-associated high mobility group box -0.00880243
IFIH1 interferon induced with helicase C domain 1 -0.0087865
GPR137B G protein-coupled receptor 137B -0.0087047
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.0086795
BAMBI BMP and activin membrane-bound inhibitor -0.00864366
PITX3 paired-like homeodomain 3 -0.00862378
HIST1H2AC histone cluster 1, H2ac -0.00855804
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00854145
S100A9 S100 calcium binding protein A9 -0.00851529
SCGB1D2 secretoglobin, family 1D, member 2 -0.00843598
FOSL2 FOS-like antigen 2 -0.00841099
NLRP2 NLR family, pyrin domain containing 2 -0.00838299
TFPI2 tissue factor pathway inhibitor 2 -0.00835238
ANXA1 annexin A1 -0.00831328
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00830755
PNMA2 paraneoplastic Ma antigen 2 -0.00830145
CKAP4 cytoskeleton-associated protein 4 -0.0082846
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00825253
CST7 cystatin F (leukocystatin) -0.00823853
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.0082333
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.0081704
SP100 SP100 nuclear antigen -0.0081568
OXTR oxytocin receptor -0.008121
CSTA cystatin A (stefin A) -0.00809102
GSDMB gasdermin B -0.00808128
PEG10 paternally expressed 10 -0.00806334
VEGFA vascular endothelial growth factor A -0.00803762
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.00802155
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00801215
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -0.00798525
BTN3A3 butyrophilin, subfamily 3, member A3 -0.0079743
SAMD9 sterile alpha motif domain containing 9 -0.00789164
CSRP2 cysteine and glycine-rich protein 2 -0.00788583
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00785697
MYBPC1 myosin binding protein C, slow type -0.00784604
HSPA2 heat shock 70kDa protein 2 -0.0078213
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.00780001
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -0.00779147
COL6A3 collagen, type VI, alpha 3 -0.00775955
NBR1 neighbor of BRCA1 gene 1 -0.00772761
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00772253
CTSA cathepsin A -0.00767496
GSDME gasdermin E -0.00767135
CLTB clathrin, light chain B -0.00766991
RNF167 ring finger protein 167 -0.00764997
JAG1 jagged 1 -0.0076465
OASL 2'-5'-oligoadenylate synthetase-like -0.00764069
SYNM synemin, intermediate filament protein -0.00762621
ABHD4 abhydrolase domain containing 4 -0.00759984
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -0.00757675
WDR45 WD repeat domain 45 -0.00754765
KRT6B keratin 6B, type II -0.00754744
KRT16 keratin 16, type I -0.00754369
MMP19 matrix metallopeptidase 19 -0.0075385
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.00753659
GRN granulin -0.00752893
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00750991
IGLL1 immunoglobulin lambda-like polypeptide 1 -0.00750452
WT1 Wilms tumor 1 -0.00750182
MBNL2 muscleblind-like splicing regulator 2 -0.00749879
JARID2 jumonji, AT rich interactive domain 2 -0.00747997
LTF lactotransferrin -0.00744927
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00744211
A2M alpha-2-macroglobulin -0.00742275
KLHL24 kelch-like family member 24 -0.00742262
OLFM4 olfactomedin 4 -0.0074128
TAPBP TAP binding protein (tapasin) -0.00740395
MYO1C myosin IC -0.007387
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00735726
HSP90B2P heat shock protein 90kDa beta (Grp94), member 2, pseudogene -0.00735165
LAMC2 laminin, gamma 2 -0.00735134
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00734002
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00733185
TRIM29 tripartite motif containing 29 -0.00733066
ECM1 extracellular matrix protein 1 -0.00732145
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 -0.00731751
RRAS related RAS viral (r-ras) oncogene homolog -0.00731135
IL1B interleukin 1, beta -0.00730207
PTPRK protein tyrosine phosphatase, receptor type, K -0.00729662
WFDC1 WAP four-disulfide core domain 1 -0.0072876
TYRP1 tyrosinase-related protein 1 -0.00727643
IRF6 interferon regulatory factor 6 -0.0072596
RGS1 regulator of G-protein signaling 1 -0.00724749
TLE4 transducin-like enhancer of split 4 -0.00724651
QPCT glutaminyl-peptide cyclotransferase -0.00722566
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.00722355
OPTN optineurin -0.00721388
AKT3 v-akt murine thymoma viral oncogene homolog 3 -0.00721076
MT1X metallothionein 1X -0.0071757
CRYAB crystallin, alpha B -0.00717088
SCGB2A2 secretoglobin, family 2A, member 2 -0.00717051
PRSS21 protease, serine, 21 (testisin) -0.00715576
KLF4 Kruppel-like factor 4 (gut) -0.00715533
RTP4 receptor (chemosensory) transporter protein 4 -0.00715399
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00714784
SP110 SP110 nuclear body protein -0.00713606
SELE selectin E -0.00713361
ISG15 ISG15 ubiquitin-like modifier -0.00711369
MSMB microseminoprotein, beta- -0.007099
LCK LCK proto-oncogene, Src family tyrosine kinase -0.00708837
CRYBG1 crystallin beta-gamma domain containing 1 -0.00708278
GPRC5B G protein-coupled receptor, class C, group 5, member B -0.00706129
QPRT quinolinate phosphoribosyltransferase -0.00702899
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00699595
MIA melanoma inhibitory activity -0.00699525
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 -0.00698626
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00698522
PODXL podocalyxin-like -0.00697236
MTUS1 microtubule associated tumor suppressor 1 -0.00696363
DIPK1A divergent protein kinase domain 1A -0.00695647
RGCC regulator of cell cycle -0.00693949
GOLGB1 golgin B1 -0.00692115
LPAR6 lysophosphatidic acid receptor 6 -0.00691764
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0069152
INAVA innate immunity activator -0.00691122
H1-2 H1.2 linker histone, cluster member -0.00690032
MX2 MX dynamin-like GTPase 2 -0.00688307
KRT17 keratin 17, type I -0.00682642
C5AR1 complement component 5a receptor 1 -0.00681165
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00681143
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00680556
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00679851
TARBP1 TAR (HIV-1) RNA binding protein 1 -0.00675979
ASCC2 activating signal cointegrator 1 complex subunit 2 -0.00673343
KLF2 Kruppel-like factor 2 -0.00671815
IFI16 interferon, gamma-inducible protein 16 -0.00670345
BCL2A1 BCL2-related protein A1 -0.00669229
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00669134
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.00668959
MARCKSL1 MARCKS-like 1 -0.00668669
RCAN1 regulator of calcineurin 1 -0.00667252
CFB complement factor B -0.00666991
OGN osteoglycin -0.00666032
DNMBP dynamin binding protein -0.0066542
CRABP2 cellular retinoic acid binding protein 2 -0.00664271
SCEL sciellin -0.0066407
DDIT3 DNA-damage-inducible transcript 3 -0.00661068
IRF9 interferon regulatory factor 9 -0.00660974
PRKCA protein kinase C, alpha -0.00658599
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -0.00658308
MID1 midline 1 -0.00658265
CRELD2 cysteine-rich with EGF-like domains 2 -0.00657779
MED22 mediator complex subunit 22 -0.00654746
PDLIM1 PDZ and LIM domain 1 -0.00653134
IGF1R insulin-like growth factor 1 receptor -0.00652552
TRAF3IP2 TRAF3 interacting protein 2 -0.00652422
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -0.00650557
CLCA2 chloride channel accessory 2 -0.00649124
LAMA2 laminin, alpha 2 -0.00645237
NT5E 5'-nucleotidase, ecto (CD73) -0.00644643
RAB5B RAB5B, member RAS oncogene family -0.00644375
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -0.00643666
S100A12 S100 calcium binding protein A12 -0.00639015
UXT ubiquitously-expressed, prefoldin-like chaperone -0.00637215
SIK1 salt-inducible kinase 1 -0.00635921
PRUNE2 prune homolog 2 (Drosophila) -0.00635419
NES nestin -0.00635058
DSP desmoplakin -0.00633031
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00631263
HSPH1 heat shock 105kDa/110kDa protein 1 -0.00629122
COPG1 coatomer protein complex, subunit gamma 1 -0.00628087
THBS3 thrombospondin 3 -0.00626322
FAM171A1 family with sequence similarity 171, member A1 -0.00626123
LYPD3 LY6/PLAUR domain containing 3 -0.00625812
BHLHE41 basic helix-loop-helix family, member e41 -0.00625388
IL1A interleukin 1, alpha -0.00625367