BCL3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description B-cell CLL/lymphoma 3|This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 602)
External Link http://www.ncbi.nlm.nih.gov/gene/602
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Genes

52 interacting proteins for BCL3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ANKRD28 ankyrin repeat domain 28
BAG2 BCL2-associated athanogene 2
BARD1 BRCA1 associated RING domain 1
BCL10 B-cell CLL/lymphoma 10
COPS5 COP9 signalosome subunit 5
CREBBP CREB binding protein
CTBP1 C-terminal binding protein 1
CTBP2 C-terminal binding protein 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYLD cylindromatosis (turban tumor syndrome)
EP300 E1A binding protein p300
ESR1 estrogen receptor 1
FBXW8 F-box and WD repeat domain containing 8
FOS FBJ murine osteosarcoma viral oncogene homolog
FYN FYN proto-oncogene, Src family tyrosine kinase
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2B general transcription factor IIB
HDAC1 histone deacetylase 1
HDAC3 histone deacetylase 3
HDAC6 histone deacetylase 6
HSPA4 heat shock 70kDa protein 4
JUN jun proto-oncogene
KAT5 K(lysine) acetyltransferase 5
KDM1A lysine (K)-specific demethylase 1A
LCK LCK proto-oncogene, Src family tyrosine kinase
MAPK3 mitogen-activated protein kinase 3
N4BP2 NEDD4 binding protein 2
NCOA1 nuclear receptor coactivator 1
NCOA6 nuclear receptor coactivator 6
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
PIR pirin (iron-binding nuclear protein)
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
RAB9A RAB9A, member RAS oncogene family
RCOR1 REST corepressor 1
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
RXRA retinoid X receptor, alpha
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIN3A SIN3 transcription regulator family member A
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBP TATA box binding protein
TP53 tumor protein p53
UBC ubiquitin C