BCL6 Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description B-cell CLL/lymphoma 6|The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2008] (NCBI Entrez Gene Database, 604)
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Genes

4 target genes of the BCL6 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
BCORL1 BCL6 corepressor-like 1
MCOLN3 mucolipin 3
NOVA2 neuro-oncological ventral antigen 2