BCL6 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description B-cell CLL/lymphoma 6|The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2008] (NCBI Entrez Gene Database, 604)
External Link http://www.ncbi.nlm.nih.gov/gene/604
Similar Terms
Downloads & Tools

Genes

115 interacting proteins for BCL6 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ARHGAP35 Rho GTPase activating protein 35
ARID1A AT rich interactive domain 1A (SWI-like)
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATF7 activating transcription factor 7
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL6B B-cell CLL/lymphoma 6, member B
BCOR BCL6 corepressor
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CDK19 cyclin-dependent kinase 19
CDK8 cyclin-dependent kinase 8
CHD3 chromodomain helicase DNA binding protein 3
CREBBP CREB binding protein
CSMD1 CUB and Sushi multiple domains 1
CTBP1 C-terminal binding protein 1
CUL1 cullin 1
CUL3 cullin 3
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNAH9 dynein, axonemal, heavy chain 9
DROSHA drosha, ribonuclease type III
E2F3 E2F transcription factor 3
EBF1 early B-cell factor 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
ELF1 E74-like factor 1 (ets domain transcription factor)
ENO1 enolase 1, (alpha)
EP300 E1A binding protein p300
EPHB6 EPH receptor B6
ERCC5 excision repair cross-complementation group 5
FBXO11 F-box protein 11
FOXM1 forkhead box M1
HBEGF heparin-binding EGF-like growth factor
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HDAC9 histone deacetylase 9
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HSF4 heat shock transcription factor 4
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IDI2 isopentenyl-diphosphate delta isomerase 2
IRF4 interferon regulatory factor 4
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KDM2A lysine (K)-specific demethylase 2A
KIF13B kinesin family member 13B
KMT2B lysine (K)-specific methyltransferase 2B
LPAR2 lysophosphatidic acid receptor 2
LPAR4 lysophosphatidic acid receptor 4
LSM1 LSM1, U6 small nuclear RNA associated
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MBD3 methyl-CpG binding domain protein 3
MED17 mediator complex subunit 17
MED23 mediator complex subunit 23
MED6 mediator complex subunit 6
MTA3 metastasis associated 1 family, member 3
MTMR6 myotubularin related protein 6
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NKRF NFKB repressing factor
OLA1 Obg-like ATPase 1
OSBPL1A oxysterol binding protein-like 1A
PANX3 pannexin 3
PARP12 poly (ADP-ribose) polymerase family, member 12
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDH9 protocadherin 9
PIAS2 protein inhibitor of activated STAT, 2
PIKFYVE phosphoinositide kinase, FYVE finger containing
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PML promyelocytic leukemia
POU2F3 POU class 2 homeobox 3
PPAP2B phosphatidic acid phosphatase type 2B
PPARD peroxisome proliferator-activated receptor delta
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRKD3 protein kinase D3
PRR11 proline rich 11
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RBX1 ring-box 1, E3 ubiquitin protein ligase
RECQL RecQ helicase-like
RPS27A ribosomal protein S27a
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SAE1 SUMO1 activating enzyme subunit 1
SENP7 SUMO1/sentrin specific peptidase 7
SIN3A SIN3 transcription regulator family member A
SKP1 S-phase kinase-associated protein 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMO smoothened, frizzled class receptor
SP1 Sp1 transcription factor
SPEN spen family transcriptional repressor
SPI1 Spi-1 proto-oncogene
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRAF3IP3 TRAF3 interacting protein 3
TRIB3 tribbles pseudokinase 3
UBC ubiquitin C
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast)
WDR35 WD repeat domain 35
WNK4 WNK lysine deficient protein kinase 4
WNT16 wingless-type MMTV integration site family, member 16
YY1 YY1 transcription factor
ZBTB16 zinc finger and BTB domain containing 16
ZBTB17 zinc finger and BTB domain containing 17
ZBTB6 zinc finger and BTB domain containing 6
ZBTB7A zinc finger and BTB domain containing 7A
ZMYND8 zinc finger, MYND-type containing 8
ZNF443 zinc finger protein 443