| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/31404 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in BHT relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KDF1 | keratinocyte differentiation factor 1 | 0.93 |
| MBP | myelin basic protein | 0.67 |
| TMSB10 | thymosin beta 10 | 0.66 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.64 |
| PLIN2 | perilipin 2 | 0.56 |
| F10 | coagulation factor X | 0.51 |
| RPE | ribulose-5-phosphate-3-epimerase | 0.5 |
| GAS8 | growth arrest-specific 8 | 0.48 |
| PDGFC | platelet derived growth factor C | 0.47 |
| SUMO2 | small ubiquitin-like modifier 2 | 0.46 |
| FAM135B | family with sequence similarity 135, member B | 0.46 |
| INPP5J | inositol polyphosphate-5-phosphatase J | 0.45 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.43 |
| ZNF35 | zinc finger protein 35 | 0.42 |
| ANTKMT | adenine nucleotide translocase lysine methyltransferase | 0.42 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) | 0.41 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.41 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.41 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.39 |
| FAN1 | FANCD2/FANCI-associated nuclease 1 | 0.38 |
| ASTE1 | asteroid homolog 1 (Drosophila) | 0.37 |
| CROCC2 | ciliary rootlet coiled-coil, rootletin family member 2 | 0.37 |
| FBXW4 | F-box and WD repeat domain containing 4 | 0.37 |
| SP110 | SP110 nuclear body protein | 0.37 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.36 |
| UNKL | unkempt family zinc finger-like | 0.35 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.35 |
| COX10 | COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor | 0.35 |
| HSH2D | hematopoietic SH2 domain containing | 0.34 |
| ADIRF | adipogenesis regulatory factor | 0.33 |
| SLX4IP | SLX4 interacting protein | 0.32 |
| ZBED8L | ZBED8 like | 0.32 |
| TRAIP | TRAF interacting protein | 0.32 |
| ZC4H2 | zinc finger, C4H2 domain containing | 0.32 |
| TPGS1 | tubulin polyglutamylase complex subunit 1 | 0.32 |
| SATB1 | SATB homeobox 1 | 0.31 |
| DBF4 | DBF4 zinc finger | 0.31 |
| RTN4RL2 | reticulon 4 receptor-like 2 | 0.31 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.31 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 0.31 |
| ARSG | arylsulfatase G | 0.31 |
| ARHGEF39 | Rho guanine nucleotide exchange factor (GEF) 39 | 0.31 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.3 |
| BORCS5 | BLOC-1 related complex subunit 5 | 0.3 |
| DEPDC1 | DEP domain containing 1 | 0.3 |
| CUEDC2 | CUE domain containing 2 | 0.3 |
| KDM8 | lysine (K)-specific demethylase 8 | 0.3 |
| DOCK11 | dedicator of cytokinesis 11 | 0.3 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.3 |
| ANKRD13B | ankyrin repeat domain 13B | 0.29 |
| KANK3 | KN motif and ankyrin repeat domains 3 | 0.29 |
| MIDN | midnolin | 0.29 |
| MARCKSL1 | MARCKS-like 1 | 0.29 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 | 0.29 |
| ZNF611 | zinc finger protein 611 | 0.28 |
| SAV1 | salvador family WW domain containing protein 1 | 0.28 |
| DSTYK | dual serine/threonine and tyrosine protein kinase | 0.28 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic | 0.28 |
| LYRM1 | LYR motif containing 1 | 0.28 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.28 |
| SMAD3 | SMAD family member 3 | 0.28 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.28 |
| ZGRF1 | zinc finger, GRF-type containing 1 | 0.28 |
| FN1 | fibronectin 1 | 0.28 |
| KIAA1143 | KIAA1143 | 0.28 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.28 |
| CDC42SE2 | CDC42 small effector 2 | 0.28 |
| SERINC5 | serine incorporator 5 | 0.27 |
| ABTB1 | ankyrin repeat and BTB (POZ) domain containing 1 | 0.27 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.27 |
| KAZN | kazrin, periplakin interacting protein | 0.27 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.27 |
| STX1A | syntaxin 1A (brain) | 0.27 |
| UBTD2 | ubiquitin domain containing 2 | 0.27 |
| KCTD18 | potassium channel tetramerization domain containing 18 | 0.27 |
| LGALSL | lectin, galactoside-binding-like | 0.27 |
| PRSS23 | protease, serine, 23 | 0.27 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | 0.27 |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 | 0.27 |
| IP6K2 | inositol hexakisphosphate kinase 2 | 0.27 |
| C15ORF61 | chromosome 15 open reading frame 61 | 0.27 |
| ALKBH5 | AlkB family member 5, RNA demethylase | 0.26 |
| PRIMPOL | primase and polymerase (DNA-directed) | 0.26 |
| ATP5PF | ATP synthase peripheral stalk subunit F6 | 0.26 |
| SPIN4 | spindlin family, member 4 | 0.26 |
| TCEA3 | transcription elongation factor A (SII), 3 | 0.26 |
| GXYLT1 | glucoside xylosyltransferase 1 | 0.26 |
| AMPD1 | adenosine monophosphate deaminase 1 | 0.26 |
| PARPBP | PARP1 binding protein | 0.26 |
| RBPJL | recombination signal binding protein for immunoglobulin kappa J region-like | 0.25 |
| CWC15 | CWC15 spliceosome-associated protein | 0.25 |
| CEP85L | centrosomal protein 85kDa-like | 0.25 |
| SLC16A6 | solute carrier family 16, member 6 | 0.25 |
| C2ORF42 | chromosome 2 open reading frame 42 | 0.25 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.25 |
| SF3B5 | splicing factor 3b, subunit 5, 10kDa | 0.25 |
| C15ORF41 | chromosome 15 open reading frame 41 | 0.25 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.25 |
| L1RE1 | LINE1 retrotransposable element 1 | 0.25 |
| DDTL | D-dopachrome tautomerase-like | 0.25 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DIPK1B | divergent protein kinase domain 1B | -3.31 |
| DES | desmin | -2.48 |
| KMT2B | lysine (K)-specific methyltransferase 2B | -1.89 |
| GVINP1 | GTPase, very large interferon inducible pseudogene 1 | -1.81 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -1.07 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.85 |
| ZNF697 | zinc finger protein 697 | -0.76 |
| HMCN1 | hemicentin 1 | -0.74 |
| TBC1D16 | TBC1 domain family, member 16 | -0.73 |
| IER2 | immediate early response 2 | -0.72 |
| TRAF3 | TNF receptor-associated factor 3 | -0.68 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.67 |
| MRAS | muscle RAS oncogene homolog | -0.63 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | -0.58 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | -0.55 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.55 |
| USB1 | U6 snRNA biogenesis 1 | -0.55 |
| PKM | pyruvate kinase, muscle | -0.53 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) | -0.53 |
| PCSK9 | proprotein convertase subtilisin/kexin type 9 | -0.53 |
| CHCHD4 | coiled-coil-helix-coiled-coil-helix domain containing 4 | -0.51 |
| ZNF564 | zinc finger protein 564 | -0.49 |
| ZNF226 | zinc finger protein 226 | -0.48 |
| GSE1 | Gse1 coiled-coil protein | -0.48 |
| TMC5 | transmembrane channel-like 5 | -0.46 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.45 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 | -0.45 |
| FKBP7 | FK506 binding protein 7 | -0.43 |
| NUCB2 | nucleobindin 2 | -0.43 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.42 |
| RMDN2 | regulator of microtubule dynamics 2 | -0.42 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) | -0.41 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.41 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 | -0.4 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.4 |
| DNAJC30 | DnaJ (Hsp40) homolog, subfamily C, member 30 | -0.4 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.4 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.38 |
| IFT57 | intraflagellar transport 57 | -0.38 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.38 |
| UBE2A | ubiquitin-conjugating enzyme E2A | -0.38 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.38 |
| DGKE | diacylglycerol kinase, epsilon 64kDa | -0.38 |
| MT-ND4 | NADH dehydrogenase, subunit 4 (complex I) | -0.38 |
| DNAH2 | dynein, axonemal, heavy chain 2 | -0.37 |
| KIAA0513 | KIAA0513 | -0.37 |
| NLGN2 | neuroligin 2 | -0.37 |
| ARL14EPL | ADP-ribosylation factor-like 14 effector protein-like | -0.37 |
| RPGR | retinitis pigmentosa GTPase regulator | -0.36 |
| STON2 | stonin 2 | -0.36 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | -0.36 |
| TOX2 | TOX high mobility group box family member 2 | -0.35 |
| CILP2 | cartilage intermediate layer protein 2 | -0.35 |
| ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 | -0.35 |
| VWA5B2 | von Willebrand factor A domain containing 5B2 | -0.35 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 | -0.35 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.35 |
| TMEM184C | transmembrane protein 184C | -0.34 |
| NMU | neuromedin U | -0.34 |
| PNPO | pyridoxamine 5'-phosphate oxidase | -0.33 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 | -0.33 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -0.33 |
| ERG28 | ergosterol biosynthesis 28 homolog | -0.32 |
| TM7SF3 | transmembrane 7 superfamily member 3 | -0.31 |
| LAMA3 | laminin, alpha 3 | -0.31 |
| RPLP1 | ribosomal protein, large, P1 | -0.31 |
| MSMO1 | methylsterol monooxygenase 1 | -0.3 |
| GCSH | glycine cleavage system protein H (aminomethyl carrier) | -0.3 |
| JMJD4 | jumonji domain containing 4 | -0.3 |
| ADCK5 | aarF domain containing kinase 5 | -0.29 |
| B2M | beta-2-microglobulin | -0.29 |
| LMO4 | LIM domain only 4 | -0.29 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.29 |
| MED19 | mediator complex subunit 19 | -0.29 |
| PRODH | proline dehydrogenase (oxidase) 1 | -0.29 |
| LARP6 | La ribonucleoprotein domain family, member 6 | -0.28 |
| CSNK1G2 | casein kinase 1, gamma 2 | -0.28 |
| ZNF445 | zinc finger protein 445 | -0.28 |
| ARHGAP44 | Rho GTPase activating protein 44 | -0.28 |
| ATP6V0C | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | -0.28 |
| GATD1 | glutamine amidotransferase class 1 domain containing 1 | -0.28 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.28 |
| PPP1R2B | PPP1R2 family member B | -0.28 |
| CCDC97 | coiled-coil domain containing 97 | -0.28 |
| PLEK | pleckstrin | -0.27 |
| ZNF224 | zinc finger protein 224 | -0.27 |
| DNAAF2 | dynein, axonemal, assembly factor 2 | -0.27 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) | -0.27 |
| UBQLN4 | ubiquilin 4 | -0.27 |
| AURKAIP1 | aurora kinase A interacting protein 1 | -0.27 |
| MYL12B | myosin, light chain 12B, regulatory | -0.26 |
| RAB40C | RAB40C, member RAS oncogene family | -0.26 |
| ATP5F1D | ATP synthase F1 subunit delta | -0.26 |
| ENO1 | enolase 1, (alpha) | -0.26 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | -0.26 |
| GORASP1 | golgi reassembly stacking protein 1, 65kDa | -0.26 |
| KIAA1107 | KIAA1107 | -0.26 |
| ITGA7 | integrin, alpha 7 | -0.26 |
| ALG2 | ALG2, alpha-1,3/1,6-mannosyltransferase | -0.26 |
