| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | BI-3406 perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the BI-3406_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.297427 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.237921 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.181608 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.160455 |
| NLGN1 | neuroligin 1 | 0.136196 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.135543 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.100256 |
| HMGA2 | high mobility group AT-hook 2 | 0.0987435 |
| TPI1 | triosephosphate isomerase 1 | 0.0904168 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0813163 |
| AHNAK | AHNAK nucleoprotein | 0.0801502 |
| DST | dystonin | 0.0796395 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0695807 |
| RACK1 | receptor for activated C kinase 1 | 0.0664703 |
| TMSB10 | thymosin beta 10 | 0.0631713 |
| ADIPOR2 | adiponectin receptor 2 | 0.0614362 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0606353 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0585679 |
| CALR | calreticulin | 0.0573334 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0550886 |
| PCDH7 | protocadherin 7 | 0.0544972 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0508061 |
| LDHA | lactate dehydrogenase A | 0.0489649 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0478715 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.044692 |
| ENO1 | enolase 1, (alpha) | 0.0434961 |
| CLDN1 | claudin 1 | 0.043086 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0413971 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0411556 |
| ACTG1 | actin gamma 1 | 0.0388 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0378999 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0368684 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0368232 |
| RPL3 | ribosomal protein L3 | 0.0367859 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0365077 |
| EHBP1 | EH domain binding protein 1 | 0.0355387 |
| RPL4 | ribosomal protein L4 | 0.035013 |
| RPL23 | ribosomal protein L23 | 0.0346952 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0344387 |
| RASAL2 | RAS protein activator like 2 | 0.0331237 |
| CMIP | c-Maf inducing protein | 0.032934 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0326183 |
| RPS4X | ribosomal protein S4, X-linked | 0.0317833 |
| ANXA1 | annexin A1 | 0.0311539 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0310741 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0309712 |
| PRDX1 | peroxiredoxin 1 | 0.0305545 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0300694 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0290967 |
| TGM2 | transglutaminase 2 | 0.0289575 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.028637 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0285668 |
| CCND1 | cyclin D1 | 0.0281538 |
| PTMA | prothymosin, alpha | 0.0280437 |
| FLNA | filamin A, alpha | 0.0277027 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0270856 |
| CDK6 | cyclin-dependent kinase 6 | 0.0270587 |
| TPM4 | tropomyosin 4 | 0.0263398 |
| EGR1 | early growth response 1 | 0.0262904 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0261957 |
| YBX1 | Y box binding protein 1 | 0.0257015 |
| TPM3 | tropomyosin 3 | 0.0256837 |
| FAT1 | FAT atypical cadherin 1 | 0.0254795 |
| HDAC9 | histone deacetylase 9 | 0.0252418 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0244851 |
| TUBB | tubulin, beta class I | 0.0244582 |
| YAP1 | Yes-associated protein 1 | 0.0244005 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0243653 |
| FSTL5 | follistatin-like 5 | 0.0241402 |
| CCN2 | cellular communication network factor 2 | 0.0240722 |
| PKM | pyruvate kinase, muscle | 0.0239476 |
| CEP112 | centrosomal protein 112kDa | 0.0239263 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0239092 |
| SKIL | SKI-like proto-oncogene | 0.0237977 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0237848 |
| INTS6 | integrator complex subunit 6 | 0.0237175 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0236019 |
| UBB | ubiquitin B | 0.0231668 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0227493 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0226615 |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 0.0225956 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0225616 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0222901 |
| FOXP1 | forkhead box P1 | 0.0222089 |
| RNF213 | ring finger protein 213 | 0.0221578 |
| ETV6 | ets variant 6 | 0.0221014 |
| PDGFC | platelet derived growth factor C | 0.0220383 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0215964 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0213276 |
| EZR | ezrin | 0.0211725 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0211711 |
| GNAS | GNAS complex locus | 0.0211554 |
| JUN | jun proto-oncogene | 0.0210148 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0209802 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0208243 |
| CANX | calnexin | 0.0207931 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0204205 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0203477 |
| TUBA1B | tubulin, alpha 1b | 0.0202912 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0202738 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | -0.223061 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0941491 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0662605 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0635334 |
| RPS2 | ribosomal protein S2 | -0.0624769 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0535958 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0515896 |
| CPOX | coproporphyrinogen oxidase | -0.0514602 |
| MMP12 | matrix metallopeptidase 12 | -0.0513427 |
| CCNL1 | cyclin L1 | -0.0492963 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0472298 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0470143 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0437355 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0427633 |
| TXNRD1 | thioredoxin reductase 1 | -0.0413362 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0412275 |
| FBXO11 | F-box protein 11 | -0.0409408 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0401176 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0394751 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0387868 |
| TMEM41B | transmembrane protein 41B | -0.0382392 |
| NKTR | natural killer cell triggering receptor | -0.0381552 |
| MED13L | mediator complex subunit 13-like | -0.0381402 |
| ZNF292 | zinc finger protein 292 | -0.0372827 |
| RTN4 | reticulon 4 | -0.0369852 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0366818 |
| XPO1 | exportin 1 | -0.0351441 |
| GOLGA4 | golgin A4 | -0.0338613 |
| CEP192 | centrosomal protein 192kDa | -0.0336325 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0335626 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.033556 |
| TNPO1 | transportin 1 | -0.0330689 |
| NEK7 | NIMA-related kinase 7 | -0.032769 |
| MGAT4C | MGAT4 family, member C | -0.0323285 |
| YEATS2 | YEATS domain containing 2 | -0.0323134 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0319988 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.031969 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0319679 |
| OGA | O-GlcNAcase | -0.0319124 |
| THOC1 | THO complex 1 | -0.0314476 |
| RPL38 | ribosomal protein L38 | -0.0313727 |
| CEP95 | centrosomal protein 95kDa | -0.0306588 |
| SETD5 | SET domain containing 5 | -0.030582 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0302865 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0302458 |
| PREPL | prolyl endopeptidase-like | -0.0298662 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0297539 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0296906 |
| EPHA6 | EPH receptor A6 | -0.0296048 |
| JMJD1C | jumonji domain containing 1C | -0.0292924 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0290134 |
| EXOC6B | exocyst complex component 6B | -0.0285819 |
| RPLP2 | ribosomal protein, large, P2 | -0.0284053 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0281612 |
| CDK19 | cyclin-dependent kinase 19 | -0.0280933 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0280153 |
| LRP6 | low density lipoprotein receptor-related protein 6 | -0.0276918 |
| VMP1 | vacuole membrane protein 1 | -0.0276818 |
| SPAG9 | sperm associated antigen 9 | -0.0275201 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0274808 |
| RNF13 | ring finger protein 13 | -0.0274179 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0269609 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.026746 |
| ANKRD36 | ankyrin repeat domain 36 | -0.0264659 |
| PNN | pinin, desmosome associated protein | -0.0258647 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0257374 |
| USP34 | ubiquitin specific peptidase 34 | -0.0254341 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0252789 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0252154 |
| RPS29 | ribosomal protein S29 | -0.0251554 |
| KLHL24 | kelch-like family member 24 | -0.0246796 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0246574 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0245324 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0240959 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0237185 |
| THOC2 | THO complex 2 | -0.0236682 |
| SLC49A4 | solute carrier family 49 member 4 | -0.023498 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0234464 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.023423 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0232181 |
| HSPA4 | heat shock 70kDa protein 4 | -0.0231144 |
| ATP11B | ATPase, class VI, type 11B | -0.0228234 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0228077 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0227662 |
| RPS21 | ribosomal protein S21 | -0.0227629 |
| KIF5B | kinesin family member 5B | -0.0226118 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0225027 |
| RSF1 | remodeling and spacing factor 1 | -0.0224783 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0224203 |
| CLTC | clathrin, heavy chain (Hc) | -0.0223729 |
| RASA2 | RAS p21 protein activator 2 | -0.0222846 |
| RBM39 | RNA binding motif protein 39 | -0.0222453 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0220842 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0219078 |
| IL6ST | interleukin 6 signal transducer | -0.0217655 |
| GRB2 | growth factor receptor-bound protein 2 | -0.021691 |
| WDR41 | WD repeat domain 41 | -0.0214783 |
| SBF2 | SET binding factor 2 | -0.0214289 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0213612 |
| ZNF207 | zinc finger protein 207 | -0.0213004 |
