| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | BI-3406 perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the BI-3406_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.15383 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.12537 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.115517 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0755889 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0457297 |
| HDAC9 | histone deacetylase 9 | 0.0427111 |
| NAV2 | neuron navigator 2 | 0.0421027 |
| FN1 | fibronectin 1 | 0.0398691 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0388995 |
| FLNA | filamin A, alpha | 0.0382167 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0375788 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0370877 |
| ARRDC3 | arrestin domain containing 3 | 0.0340646 |
| RPL3 | ribosomal protein L3 | 0.0340468 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.031584 |
| SMAD3 | SMAD family member 3 | 0.0314687 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0295304 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0290441 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0285939 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0283381 |
| AHR | aryl hydrocarbon receptor | 0.0279236 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0270162 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0261548 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0258648 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0252239 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0249853 |
| YBX1 | Y box binding protein 1 | 0.0240913 |
| PCBP2 | poly(rC) binding protein 2 | 0.0234793 |
| MYOF | myoferlin | 0.0228391 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0220021 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0217923 |
| RPL4 | ribosomal protein L4 | 0.0209329 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0203 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0202703 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.019956 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0199047 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0196451 |
| TPM3 | tropomyosin 3 | 0.0196336 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0190401 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.018822 |
| MSN | moesin | 0.0187912 |
| RPL7 | ribosomal protein L7 | 0.0187645 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0187246 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0184531 |
| TAPBP | TAP binding protein (tapasin) | 0.018267 |
| EZR | ezrin | 0.0181301 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0179729 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0178459 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0177576 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0176015 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0174136 |
| RPS4X | ribosomal protein S4, X-linked | 0.0174122 |
| DUSP10 | dual specificity phosphatase 10 | 0.0174057 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0172755 |
| ANXA1 | annexin A1 | 0.0172312 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0171841 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0168569 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0166836 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0166032 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0160875 |
| MX1 | MX dynamin-like GTPase 1 | 0.0159308 |
| FNDC3B | fibronectin type III domain containing 3B | 0.015922 |
| RPS2 | ribosomal protein S2 | 0.0156705 |
| GOLGB1 | golgin B1 | 0.0156671 |
| DSTN | destrin (actin depolymerizing factor) | 0.0155485 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0154061 |
| AHNAK | AHNAK nucleoprotein | 0.0153496 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0145698 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0145356 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0145069 |
| VCAN | versican | 0.0144681 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0144402 |
| RACK1 | receptor for activated C kinase 1 | 0.0144168 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0140956 |
| OPTN | optineurin | 0.0140515 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.013956 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0137803 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0137725 |
| LDHA | lactate dehydrogenase A | 0.0136855 |
| CD164 | CD164 molecule, sialomucin | 0.0136348 |
| MKI67 | marker of proliferation Ki-67 | 0.0135247 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0133353 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.013252 |
| CENPF | centromere protein F, 350/400kDa | 0.0131853 |
| JMJD1C | jumonji domain containing 1C | 0.0130665 |
| FNIP1 | folliculin interacting protein 1 | 0.012933 |
| SPAG9 | sperm associated antigen 9 | 0.0129254 |
| PKM | pyruvate kinase, muscle | 0.0128303 |
| SVIL | supervillin | 0.0128 |
| DSPP | dentin sialophosphoprotein | 0.0127918 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0127881 |
| GPR176 | G protein-coupled receptor 176 | 0.0127643 |
| NONO | non-POU domain containing, octamer-binding | 0.012727 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0126377 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0126205 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0126015 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0125935 |
| IPO7 | importin 7 | 0.0123854 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0123614 |
| FAT1 | FAT atypical cadherin 1 | 0.0122667 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.223096 |
| HLA-B | major histocompatibility complex, class I, B | -0.14647 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.140332 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.122175 |
| IER3 | immediate early response 3 | -0.117024 |
| TMSB10 | thymosin beta 10 | -0.0872371 |
| FTL | ferritin, light polypeptide | -0.0796817 |
| FRMD4A | FERM domain containing 4A | -0.0678896 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0673254 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0664304 |
| PTMA | prothymosin, alpha | -0.0633552 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0596664 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0581592 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0575632 |
| RPL35A | ribosomal protein L35a | -0.0535847 |
| GLIS3 | GLIS family zinc finger 3 | -0.0521275 |
| ADM | adrenomedullin | -0.0521156 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0517646 |
| RPS24 | ribosomal protein S24 | -0.0445631 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0419 |
| MT2A | metallothionein 2A | -0.0416523 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0413437 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0411613 |
| COL1A1 | collagen, type I, alpha 1 | -0.0402633 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0391555 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0371492 |
| RPL37A | ribosomal protein L37a | -0.0365067 |
| RPLP2 | ribosomal protein, large, P2 | -0.0363763 |
| HLA-A | major histocompatibility complex, class I, A | -0.0353332 |
| RPS21 | ribosomal protein S21 | -0.0340774 |
| RAI14 | retinoic acid induced 14 | -0.0334163 |
| NDRG1 | N-myc downstream regulated 1 | -0.0330867 |
| GNAS | GNAS complex locus | -0.0326854 |
| RPS6 | ribosomal protein S6 | -0.0321477 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0313536 |
| EGR1 | early growth response 1 | -0.0312008 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0310688 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0307098 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0306326 |
| DIAPH2 | diaphanous-related formin 2 | -0.0304033 |
| CTSD | cathepsin D | -0.0300075 |
| HMGA2 | high mobility group AT-hook 2 | -0.0297562 |
| RPLP1 | ribosomal protein, large, P1 | -0.0295562 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0282968 |
| CDH13 | cadherin 13 | -0.0282065 |
| RPL9 | ribosomal protein L9 | -0.0281877 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0279782 |
| RPS13 | ribosomal protein S13 | -0.0276859 |
| CLMP | CXADR-like membrane protein | -0.0276482 |
| RPL31 | ribosomal protein L31 | -0.027621 |
| PGK1 | phosphoglycerate kinase 1 | -0.0275985 |
| FBXO11 | F-box protein 11 | -0.0270605 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0270123 |
| RPL38 | ribosomal protein L38 | -0.0267176 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0266082 |
| RPL7A | ribosomal protein L7a | -0.0264346 |
| RPL36A | ribosomal protein L36a | -0.0263585 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0261755 |
| RPS23 | ribosomal protein S23 | -0.0259631 |
| TMSB4X | thymosin beta 4, X-linked | -0.0258675 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0256236 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0256083 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0254576 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0253388 |
| TMEM132D | transmembrane protein 132D | -0.0249225 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0247507 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0242877 |
| RPL34 | ribosomal protein L34 | -0.0228652 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0227735 |
| S100A9 | S100 calcium binding protein A9 | -0.0225241 |
| ACTG1 | actin gamma 1 | -0.0224958 |
| COL1A2 | collagen, type I, alpha 2 | -0.0224262 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0222813 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0220488 |
| CD63 | CD63 molecule | -0.0219856 |
| RPL19 | ribosomal protein L19 | -0.0217684 |
| CAVIN1 | caveolae associated protein 1 | -0.0214216 |
| NABP1 | nucleic acid binding protein 1 | -0.0213604 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0212096 |
| BNC2 | basonuclin 2 | -0.0211988 |
| RPS8 | ribosomal protein S8 | -0.0211629 |
| NAV1 | neuron navigator 1 | -0.021121 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0210942 |
| RPS10 | ribosomal protein S10 | -0.0209098 |
| KRT19 | keratin 19, type I | -0.0208299 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0206159 |
| VDAC1 | voltage-dependent anion channel 1 | -0.020457 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0203361 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0202489 |
| RPS29 | ribosomal protein S29 | -0.0200702 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0197356 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0196017 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0190761 |
| RPS27A | ribosomal protein S27a | -0.0189838 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0188957 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0186851 |
| CTSB | cathepsin B | -0.0186794 |
| RPS25 | ribosomal protein S25 | -0.0185899 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0185246 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0184837 |
