| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | BI-78D3 perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the BI-78D3_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0512993 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0477985 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0342715 |
| HDAC9 | histone deacetylase 9 | 0.0305479 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0303875 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0285685 |
| LDHA | lactate dehydrogenase A | 0.0285229 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0262801 |
| NAV2 | neuron navigator 2 | 0.0228714 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0220286 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0215713 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0212553 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0210262 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0206794 |
| CENPF | centromere protein F, 350/400kDa | 0.0193296 |
| TPM3 | tropomyosin 3 | 0.0192221 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0191754 |
| SQSTM1 | sequestosome 1 | 0.0191636 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0183518 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0179272 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0178208 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0177899 |
| CD44 | CD44 molecule (Indian blood group) | 0.0177302 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0174464 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0174084 |
| RUNX1 | runt-related transcription factor 1 | 0.0173967 |
| MAP1B | microtubule-associated protein 1B | 0.0173599 |
| CDH13 | cadherin 13 | 0.0166242 |
| ASPH | aspartate beta-hydroxylase | 0.016535 |
| MYOF | myoferlin | 0.0164349 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0156913 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0156381 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0154688 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0152876 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0148121 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0146831 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0145066 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0143462 |
| MSN | moesin | 0.0142134 |
| B2M | beta-2-microglobulin | 0.0139908 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0138981 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0137963 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0135204 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0131116 |
| CANX | calnexin | 0.0130407 |
| PCBP2 | poly(rC) binding protein 2 | 0.0128917 |
| DSPP | dentin sialophosphoprotein | 0.0126027 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0126006 |
| RTN4 | reticulon 4 | 0.0125861 |
| ANXA2 | annexin A2 | 0.0125686 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0124985 |
| TPM4 | tropomyosin 4 | 0.0124635 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0123226 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0118769 |
| ZNF292 | zinc finger protein 292 | 0.0118138 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0118028 |
| XPO1 | exportin 1 | 0.0117502 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0116341 |
| ERBIN | erbb2 interacting protein | 0.0116313 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0115835 |
| GOLGA4 | golgin A4 | 0.0113905 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.011318 |
| POTEF | POTE ankyrin domain family, member F | 0.0111813 |
| PKM | pyruvate kinase, muscle | 0.0111519 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0111153 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0111115 |
| FNIP1 | folliculin interacting protein 1 | 0.0110661 |
| ENO1 | enolase 1, (alpha) | 0.0110058 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0109903 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0109309 |
| PTK2 | protein tyrosine kinase 2 | 0.0109247 |
| SUCO | SUN domain containing ossification factor | 0.0106922 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0105877 |
| ANXA5 | annexin A5 | 0.0105741 |
| EGFR | epidermal growth factor receptor | 0.01052 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.010328 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0102814 |
| TAOK1 | TAO kinase 1 | 0.010268 |
| FSTL1 | follistatin-like 1 | 0.0102486 |
| ANO6 | anoctamin 6 | 0.010248 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0100759 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.00996731 |
| CDK6 | cyclin-dependent kinase 6 | 0.00988524 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.00986306 |
| IL6ST | interleukin 6 signal transducer | 0.00982494 |
| SET | SET nuclear proto-oncogene | 0.00980654 |
| FLNB | filamin B, beta | 0.00979823 |
| RND3 | Rho family GTPase 3 | 0.00976432 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.00973578 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.00973263 |
| DST | dystonin | 0.00963441 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.00953859 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0094681 |
| TMSB4X | thymosin beta 4, X-linked | 0.00945234 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.00931504 |
| JUN | jun proto-oncogene | 0.00917479 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00909032 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.00900061 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0089393 |
| HELZ | helicase with zinc finger | 0.00892184 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.068604 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0677957 |
| VIM | vimentin | -0.0579881 |
| PLAT | plasminogen activator, tissue | -0.0541403 |
| TMSB10 | thymosin beta 10 | -0.0421653 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0345904 |
| HLA-B | major histocompatibility complex, class I, B | -0.0334335 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0274237 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0247098 |
| LMNA | lamin A/C | -0.0246395 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0241387 |
| FBN1 | fibrillin 1 | -0.023779 |
| NDRG1 | N-myc downstream regulated 1 | -0.0193492 |
| LOX | lysyl oxidase | -0.0180679 |
| COL5A1 | collagen, type V, alpha 1 | -0.0171406 |
| COL1A2 | collagen, type I, alpha 2 | -0.0170372 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0164966 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0163504 |
| CAVIN1 | caveolae associated protein 1 | -0.0159799 |
| HLA-C | major histocompatibility complex, class I, C | -0.014525 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.014481 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0141831 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0130744 |
| THBS2 | thrombospondin 2 | -0.0126097 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0122167 |
| FN1 | fibronectin 1 | -0.0114751 |
| MX2 | MX dynamin-like GTPase 2 | -0.011265 |
| PRSS23 | protease, serine, 23 | -0.0111238 |
| LOXL2 | lysyl oxidase-like 2 | -0.0110632 |
| PODXL | podocalyxin-like | -0.0107457 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0105508 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00994329 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.00932014 |
| COL1A1 | collagen, type I, alpha 1 | -0.00891941 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.00886434 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.00837876 |
| SUCNR1 | succinate receptor 1 | -0.00777408 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00774715 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.00772206 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.00771474 |
| S100A11 | S100 calcium binding protein A11 | -0.00770865 |
| NAV1 | neuron navigator 1 | -0.00769097 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.00768457 |
| PXDN | peroxidasin | -0.00761892 |
| MT1X | metallothionein 1X | -0.00743097 |
| CTSB | cathepsin B | -0.00737928 |
| PRRX1 | paired related homeobox 1 | -0.00728127 |
| JAZF1 | JAZF zinc finger 1 | -0.00722667 |
| KRT81 | keratin 81, type II | -0.00709051 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00706288 |
| EHBP1 | EH domain binding protein 1 | -0.00705293 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.00705246 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.00673191 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00671293 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00652451 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.00649557 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.00647332 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.00643899 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00629347 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.00628668 |
| HLA-E | major histocompatibility complex, class I, E | -0.00624173 |
| MRC2 | mannose receptor, C type 2 | -0.0062318 |
| PTMA | prothymosin, alpha | -0.00620984 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.00612456 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00604677 |
| GOLGA2 | golgin A2 | -0.00600226 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.00596543 |
| FRMD4A | FERM domain containing 4A | -0.00576244 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00573714 |
| FTL | ferritin, light polypeptide | -0.00559383 |
| MEIS2 | Meis homeobox 2 | -0.00557092 |
| CD81 | CD81 molecule | -0.00556117 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00555382 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00549223 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.00544596 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.00544186 |
| RNF213 | ring finger protein 213 | -0.00537663 |
| RPL35A | ribosomal protein L35a | -0.00534501 |
| HLA-A | major histocompatibility complex, class I, A | -0.00530315 |
| INTS6 | integrator complex subunit 6 | -0.00530101 |
| FRMD5 | FERM domain containing 5 | -0.00524054 |
| TPM1 | tropomyosin 1 (alpha) | -0.00523719 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00523039 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00512637 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.00511877 |
| CCM2 | cerebral cavernous malformation 2 | -0.00509454 |
| SEC61G | Sec61 gamma subunit | -0.00485105 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.00483062 |
| MXRA5 | matrix-remodelling associated 5 | -0.00482434 |
| RRBP1 | ribosome binding protein 1 | -0.00481921 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.00478557 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.00474939 |
| MYADM | myeloid-associated differentiation marker | -0.00474917 |
| CDK12 | cyclin-dependent kinase 12 | -0.00471699 |
| CEP112 | centrosomal protein 112kDa | -0.00471287 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00465483 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0046274 |
| EDF1 | endothelial differentiation-related factor 1 | -0.00456331 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0045558 |
| THY1 | Thy-1 cell surface antigen | -0.00451669 |
