| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | BI-78D3 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the BI-78D3_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0777965 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0707573 |
| VCL | vinculin | 0.0625233 |
| FMN1 | formin 1 | 0.0587559 |
| DPH6 | diphthamine biosynthesis 6 | 0.0519541 |
| TLE4 | transducin-like enhancer of split 4 | 0.0488982 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.045882 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0446423 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0424725 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0412028 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0393579 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0387344 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0385547 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0379667 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0345402 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.033147 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0329589 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0315278 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0313826 |
| FRMD4A | FERM domain containing 4A | 0.0310377 |
| DST | dystonin | 0.0307462 |
| RPS12 | ribosomal protein S12 | 0.0298375 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0296206 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0294468 |
| NREP | neuronal regeneration related protein | 0.0290764 |
| RPS3 | ribosomal protein S3 | 0.0286974 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0286377 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0270624 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.026835 |
| MYO9A | myosin IXA | 0.0265786 |
| VCAN | versican | 0.0252558 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0246127 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0245837 |
| PLPP1 | phospholipid phosphatase 1 | 0.0242707 |
| MAP1B | microtubule-associated protein 1B | 0.0241843 |
| NRG1 | neuregulin 1 | 0.0240009 |
| PRKCA | protein kinase C, alpha | 0.0239366 |
| GSE1 | Gse1 coiled-coil protein | 0.0237852 |
| RPS6 | ribosomal protein S6 | 0.0236301 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0235797 |
| ZNF395 | zinc finger protein 395 | 0.0234981 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0234396 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0230226 |
| SP100 | SP100 nuclear antigen | 0.0229688 |
| PTEN | phosphatase and tensin homolog | 0.0229383 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0228548 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0228166 |
| ENAH | enabled homolog (Drosophila) | 0.0225453 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0223261 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0219399 |
| TPM1 | tropomyosin 1 (alpha) | 0.0218285 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0216368 |
| PCDH9 | protocadherin 9 | 0.0214597 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0213601 |
| MYO1E | myosin IE | 0.0212965 |
| SMYD3 | SET and MYND domain containing 3 | 0.0208907 |
| STXBP4 | syntaxin binding protein 4 | 0.0207646 |
| SYT1 | synaptotagmin I | 0.0206939 |
| FERMT2 | fermitin family member 2 | 0.0206428 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.020592 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0205206 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0205141 |
| RPLP0 | ribosomal protein, large, P0 | 0.0205094 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0204969 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0204134 |
| NDRG1 | N-myc downstream regulated 1 | 0.0202571 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0201429 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0201326 |
| RPL31 | ribosomal protein L31 | 0.0200758 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0199343 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0199145 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0198357 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0197009 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0196885 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0194725 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0194101 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0191703 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0190886 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0190481 |
| HDX | highly divergent homeobox | 0.018955 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0189396 |
| LSAMP | limbic system-associated membrane protein | 0.0187706 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.018714 |
| TOP1 | topoisomerase (DNA) I | 0.0185464 |
| VMP1 | vacuole membrane protein 1 | 0.018502 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0184314 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0183605 |
| SNX13 | sorting nexin 13 | 0.0182662 |
| FLT1 | fms-related tyrosine kinase 1 | 0.0182571 |
| RPS27 | ribosomal protein S27 | 0.0178879 |
| PCDH15 | protocadherin-related 15 | 0.0177618 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0176538 |
| PANK3 | pantothenate kinase 3 | 0.0175949 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0174282 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0172819 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0172192 |
| MYO6 | myosin VI | 0.0169602 |
| PALLD | palladin, cytoskeletal associated protein | 0.016945 |
| MCL1 | myeloid cell leukemia 1 | 0.0169391 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0168327 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.235799 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.172445 |
| COL1A1 | collagen, type I, alpha 1 | -0.0896979 |
| PTMA | prothymosin, alpha | -0.08866 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0614634 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0479599 |
| COL3A1 | collagen, type III, alpha 1 | -0.0418678 |
| CRH | corticotropin releasing hormone | -0.0380334 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0363257 |
| ACTG1 | actin gamma 1 | -0.0356128 |
| RPS24 | ribosomal protein S24 | -0.0355791 |
| RPS27A | ribosomal protein S27a | -0.0341934 |
| VIM | vimentin | -0.0340043 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0317275 |
| UBC | ubiquitin C | -0.0307735 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0297769 |
| RBMX | RNA binding motif protein, X-linked | -0.0297244 |
| HMGB2 | high mobility group box 2 | -0.0294183 |
| CENPF | centromere protein F, 350/400kDa | -0.0283859 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0278726 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | -0.0274702 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0268126 |
| AHNAK | AHNAK nucleoprotein | -0.0263924 |
| PARD3 | par-3 family cell polarity regulator | -0.0257417 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0255301 |
| RPL35A | ribosomal protein L35a | -0.0250691 |
| TMSB10 | thymosin beta 10 | -0.0248098 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0246366 |
| PLAT | plasminogen activator, tissue | -0.0245422 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0245303 |
| H3-3B | H3.3 histone B | -0.0235789 |
| PRRC2C | proline-rich coiled-coil 2C | -0.023481 |
| HMGB1 | high mobility group box 1 | -0.0233229 |
| LMNA | lamin A/C | -0.0231212 |
| TRIB2 | tribbles pseudokinase 2 | -0.0223846 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0222797 |
| MKI67 | marker of proliferation Ki-67 | -0.0219516 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0216255 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0215243 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0214138 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.021316 |
| NUP214 | nucleoporin 214kDa | -0.0211153 |
| GNAS | GNAS complex locus | -0.0208888 |
| MED13L | mediator complex subunit 13-like | -0.0207017 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0204006 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0203577 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0203147 |
| SCG2 | secretogranin II | -0.0201995 |
| CDH13 | cadherin 13 | -0.0201597 |
| CCND1 | cyclin D1 | -0.0200996 |
| SEPTIN2 | septin 2 | -0.0199748 |
| MED13 | mediator complex subunit 13 | -0.0199087 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0196544 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0195581 |
| S100A9 | S100 calcium binding protein A9 | -0.0192714 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0191567 |
| USP34 | ubiquitin specific peptidase 34 | -0.0190894 |
| RHEB | Ras homolog enriched in brain | -0.0190665 |
| HLA-B | major histocompatibility complex, class I, B | -0.0188808 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.0187545 |
| ZNF292 | zinc finger protein 292 | -0.0185893 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0184608 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0184466 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -0.0181329 |
| FUS | FUS RNA binding protein | -0.0181163 |
| MORF4L2 | mortality factor 4 like 2 | -0.0180766 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0179088 |
| UBE3C | ubiquitin protein ligase E3C | -0.017843 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0176957 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0176216 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0175613 |
| INHBA | inhibin, beta A | -0.0175562 |
| ZNF609 | zinc finger protein 609 | -0.017397 |
| ANXA2 | annexin A2 | -0.0173282 |
| CDK12 | cyclin-dependent kinase 12 | -0.017307 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0172458 |
| SRPK2 | SRSF protein kinase 2 | -0.0170492 |
| MAP4 | microtubule-associated protein 4 | -0.0170126 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0169622 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -0.0168567 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0168222 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0165946 |
| RPL26 | ribosomal protein L26 | -0.0164957 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | -0.016339 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0163361 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0163047 |
| HELZ | helicase with zinc finger | -0.0161683 |
| THOC2 | THO complex 2 | -0.0161422 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.016047 |
| XRN2 | 5'-3' exoribonuclease 2 | -0.0160155 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.0159166 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0156648 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.0155851 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0155684 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0155581 |
| FN1 | fibronectin 1 | -0.0155082 |
| RPL34 | ribosomal protein L34 | -0.0154906 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0154641 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | -0.0153945 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.015392 |
