| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | BI-78D3 perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the BI-78D3_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.156232 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.126171 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0815916 |
| FAT1 | FAT atypical cadherin 1 | 0.0691398 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.059358 |
| RPL12 | ribosomal protein L12 | 0.0564689 |
| RPL18 | ribosomal protein L18 | 0.0530321 |
| DSPP | dentin sialophosphoprotein | 0.052365 |
| LDHA | lactate dehydrogenase A | 0.0500306 |
| EZR | ezrin | 0.0466056 |
| RPS12 | ribosomal protein S12 | 0.0449878 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0446143 |
| RPLP0 | ribosomal protein, large, P0 | 0.0442122 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0413063 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.040921 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0393508 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0372671 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0355341 |
| LMO7 | LIM domain 7 | 0.0354393 |
| KLF6 | Kruppel-like factor 6 | 0.0351837 |
| B2M | beta-2-microglobulin | 0.0346598 |
| EPCAM | epithelial cell adhesion molecule | 0.0344106 |
| ASPH | aspartate beta-hydroxylase | 0.0335309 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0333981 |
| RPS19 | ribosomal protein S19 | 0.032902 |
| RPL26 | ribosomal protein L26 | 0.0308414 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0297907 |
| RPS4X | ribosomal protein S4, X-linked | 0.0297778 |
| KRT8 | keratin 8, type II | 0.0297164 |
| FOXP1 | forkhead box P1 | 0.0295079 |
| AHNAK | AHNAK nucleoprotein | 0.0280292 |
| RPL36 | ribosomal protein L36 | 0.0273722 |
| RPL32 | ribosomal protein L32 | 0.0271947 |
| SON | SON DNA binding protein | 0.0271946 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0270283 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0269549 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0268132 |
| ZNF292 | zinc finger protein 292 | 0.0267825 |
| PGK1 | phosphoglycerate kinase 1 | 0.0263897 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0262286 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.025445 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0250569 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0246834 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0245286 |
| ANO6 | anoctamin 6 | 0.0245079 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.024168 |
| DSG2 | desmoglein 2 | 0.0236375 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.022985 |
| RPLP1 | ribosomal protein, large, P1 | 0.0227463 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0225616 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0222711 |
| PDZD8 | PDZ domain containing 8 | 0.0221713 |
| CBX3 | chromobox homolog 3 | 0.0213687 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0213028 |
| MUC13 | mucin 13, cell surface associated | 0.021264 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0211684 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0210979 |
| EREG | epiregulin | 0.0210681 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.020985 |
| CADPS | Ca++-dependent secretion activator | 0.0209154 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0208137 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0207656 |
| YBX3 | Y box binding protein 3 | 0.0203944 |
| SHROOM3 | shroom family member 3 | 0.0203465 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.020282 |
| EMP1 | epithelial membrane protein 1 | 0.0199344 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.019898 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0197879 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0197414 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0196445 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0196187 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0195536 |
| TPI1 | triosephosphate isomerase 1 | 0.0194098 |
| SCARB2 | scavenger receptor class B, member 2 | 0.018938 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0184525 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.018433 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0183559 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0183318 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0182482 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0182235 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0181596 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0180772 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0180687 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0178738 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0177745 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0177529 |
| ERBIN | erbb2 interacting protein | 0.0175321 |
| PHF3 | PHD finger protein 3 | 0.0174883 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0172223 |
| RPL7 | ribosomal protein L7 | 0.0170975 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.017076 |
| TXNIP | thioredoxin interacting protein | 0.0170176 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0169801 |
| RPL30 | ribosomal protein L30 | 0.0169022 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0168868 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0167504 |
| RPL21 | ribosomal protein L21 | 0.0166864 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0166291 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0165461 |
| USP6NL | USP6 N-terminal like | 0.0164898 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.227085 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.202522 |
| PTMA | prothymosin, alpha | -0.166978 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.157279 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0964891 |
| NDRG1 | N-myc downstream regulated 1 | -0.0781234 |
| ACTG1 | actin gamma 1 | -0.0779667 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0719741 |
| TPM4 | tropomyosin 4 | -0.0644963 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0628342 |
| RPL35A | ribosomal protein L35a | -0.0623874 |
| NPSR1 | neuropeptide S receptor 1 | -0.0573646 |
| VCL | vinculin | -0.0504786 |
| S100P | S100 calcium binding protein P | -0.0494403 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0489132 |
| AREG | amphiregulin | -0.047037 |
| GOLGA4 | golgin A4 | -0.0470211 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0440287 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0435511 |
| TNS4 | tensin 4 | -0.0431527 |
| RPS29 | ribosomal protein S29 | -0.0425126 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0423752 |
| POTEF | POTE ankyrin domain family, member F | -0.0394254 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.039063 |
| IER3 | immediate early response 3 | -0.038819 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0371479 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0370466 |
| AGR2 | anterior gradient 2 | -0.0352928 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0341705 |
| MT2A | metallothionein 2A | -0.0339148 |
| SETD5 | SET domain containing 5 | -0.0338784 |
| HM13 | histocompatibility (minor) 13 | -0.0335845 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0326578 |
| EGR1 | early growth response 1 | -0.0323945 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0323429 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0316913 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0313654 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0313636 |
| TFF1 | trefoil factor 1 | -0.0312195 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0307997 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.03017 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0296845 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.029299 |
| CALR | calreticulin | -0.0291786 |
| RPS23 | ribosomal protein S23 | -0.0288871 |
| FTL | ferritin, light polypeptide | -0.0288064 |
| RPL13A | ribosomal protein L13a | -0.0286285 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0286023 |
| TBC1D22A | TBC1 domain family, member 22A | -0.028319 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0278492 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0272841 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0265079 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0265053 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0261226 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0261133 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0260099 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0255915 |
| RPS13 | ribosomal protein S13 | -0.0254494 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0253782 |
| VEGFA | vascular endothelial growth factor A | -0.0249906 |
| UBC | ubiquitin C | -0.0244999 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.0243441 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0240067 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0239531 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0233233 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0228244 |
| RPL9 | ribosomal protein L9 | -0.0226186 |
| BRD2 | bromodomain containing 2 | -0.0225844 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0222313 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0219385 |
| RPS8 | ribosomal protein S8 | -0.0216323 |
| RCOR1 | REST corepressor 1 | -0.0216055 |
| DNM2 | dynamin 2 | -0.0215819 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0213953 |
| NUCB2 | nucleobindin 2 | -0.0213802 |
| NKTR | natural killer cell triggering receptor | -0.0210071 |
| SEC24D | SEC24 family member D | -0.0208779 |
| COG5 | component of oligomeric golgi complex 5 | -0.0208193 |
| RPL31 | ribosomal protein L31 | -0.0208115 |
| GDF15 | growth differentiation factor 15 | -0.020803 |
| TMEM41B | transmembrane protein 41B | -0.0207769 |
| FBXO11 | F-box protein 11 | -0.0206759 |
| FDPS | farnesyl diphosphate synthase | -0.0206031 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0205586 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0205442 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.020505 |
| ITGB4 | integrin, beta 4 | -0.020333 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0199838 |
| HMGB1 | high mobility group box 1 | -0.019976 |
| MAP4 | microtubule-associated protein 4 | -0.0197506 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0197268 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0197204 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0195323 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0194897 |
| TMSB10 | thymosin beta 10 | -0.0194314 |
| SELENOK | selenoprotein K | -0.0190988 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0189082 |
| FOSL1 | FOS-like antigen 1 | -0.0188875 |
| GNAS | GNAS complex locus | -0.018654 |
| RPS11 | ribosomal protein S11 | -0.0185815 |
