| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | BI-78D3 perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the BI-78D3_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.101976 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0823299 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0737095 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0701007 |
| VCL | vinculin | 0.0607431 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0538297 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0510573 |
| VMP1 | vacuole membrane protein 1 | 0.0506713 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.05064 |
| MSN | moesin | 0.047251 |
| GOLGB1 | golgin B1 | 0.040834 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0406932 |
| KYNU | kynureninase | 0.0401037 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0381148 |
| VEGFA | vascular endothelial growth factor A | 0.0378127 |
| ATXN1 | ataxin 1 | 0.0366595 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0359888 |
| INTS6 | integrator complex subunit 6 | 0.0356279 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0356209 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0344357 |
| FRMD4A | FERM domain containing 4A | 0.0341346 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0338511 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0326057 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0326034 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0324364 |
| HMGA2 | high mobility group AT-hook 2 | 0.0312897 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0311455 |
| PDLIM5 | PDZ and LIM domain 5 | 0.031088 |
| ASPH | aspartate beta-hydroxylase | 0.0304437 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0304054 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0297585 |
| PALLD | palladin, cytoskeletal associated protein | 0.0296556 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0296337 |
| PCBP2 | poly(rC) binding protein 2 | 0.0295156 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0294344 |
| RND3 | Rho family GTPase 3 | 0.0291732 |
| GLIS3 | GLIS family zinc finger 3 | 0.0281144 |
| EGFR | epidermal growth factor receptor | 0.028111 |
| BRD2 | bromodomain containing 2 | 0.0280536 |
| FNIP1 | folliculin interacting protein 1 | 0.0278664 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0277455 |
| AHR | aryl hydrocarbon receptor | 0.0276631 |
| PDE10A | phosphodiesterase 10A | 0.0271281 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0264697 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0257875 |
| JMJD1C | jumonji domain containing 1C | 0.0256547 |
| FLNB | filamin B, beta | 0.0244994 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0244589 |
| GPC6 | glypican 6 | 0.0243799 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0242437 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0242342 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0241615 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0238013 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0234689 |
| EGR1 | early growth response 1 | 0.0230267 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0229806 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0226902 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0226848 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.022513 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0224555 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | 0.0217345 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0214434 |
| SMAD3 | SMAD family member 3 | 0.0213815 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0212509 |
| GPR176 | G protein-coupled receptor 176 | 0.0208079 |
| TUT7 | terminal uridylyl transferase 7 | 0.0207249 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0201511 |
| TMEM132D | transmembrane protein 132D | 0.0199699 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0194347 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0193395 |
| NABP1 | nucleic acid binding protein 1 | 0.0191895 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0187567 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0187323 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0186305 |
| FMNL2 | formin-like 2 | 0.0185046 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0184331 |
| NOTCH2 | notch 2 | 0.0183061 |
| LYST | lysosomal trafficking regulator | 0.0180682 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0178764 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0174841 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0173852 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0172832 |
| CD44 | CD44 molecule (Indian blood group) | 0.0172359 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0169889 |
| MYADM | myeloid-associated differentiation marker | 0.0166596 |
| ERBIN | erbb2 interacting protein | 0.0166556 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0164913 |
| TRIM55 | tripartite motif containing 55 | 0.0162606 |
| CRY1 | cryptochrome circadian clock 1 | 0.0161807 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0161406 |
| NTN4 | netrin 4 | 0.0161077 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.016092 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0159662 |
| SEPTIN9 | septin 9 | 0.0159519 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.01588 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0158761 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0156963 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0155599 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0155543 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0154675 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.125748 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.114969 |
| VIM | vimentin | -0.11108 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.108389 |
| HLA-B | major histocompatibility complex, class I, B | -0.0777607 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.063256 |
| PGK1 | phosphoglycerate kinase 1 | -0.0628955 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0627983 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0613164 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0555832 |
| IER3 | immediate early response 3 | -0.0551378 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0538636 |
| TMSB10 | thymosin beta 10 | -0.0533246 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0531094 |
| OGA | O-GlcNAcase | -0.0530254 |
| ANLN | anillin, actin binding protein | -0.0494884 |
| RPS24 | ribosomal protein S24 | -0.0478319 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0477765 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0472419 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0466003 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0454283 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0452857 |
| ZNF292 | zinc finger protein 292 | -0.0447414 |
| GNAS | GNAS complex locus | -0.0442686 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0433866 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0430337 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0430012 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0411608 |
| PTMA | prothymosin, alpha | -0.0404344 |
| AHNAK | AHNAK nucleoprotein | -0.0396897 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0391325 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.038172 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0379873 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0376927 |
| DEK | DEK proto-oncogene | -0.0373861 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0366375 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0364867 |
| RRBP1 | ribosome binding protein 1 | -0.0362853 |
| ANXA2 | annexin A2 | -0.0362247 |
| RPL26 | ribosomal protein L26 | -0.0356003 |
| TPM4 | tropomyosin 4 | -0.0352148 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0351274 |
| TUBB | tubulin, beta class I | -0.0346757 |
| RTN4 | reticulon 4 | -0.0337891 |
| RBM39 | RNA binding motif protein 39 | -0.0329691 |
| TMSB4X | thymosin beta 4, X-linked | -0.0327256 |
| FLNA | filamin A, alpha | -0.0325514 |
| MKI67 | marker of proliferation Ki-67 | -0.0324402 |
| RPL35A | ribosomal protein L35a | -0.0320718 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0318188 |
| COL1A1 | collagen, type I, alpha 1 | -0.0315362 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0306029 |
| KLF6 | Kruppel-like factor 6 | -0.0305336 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.030407 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0291205 |
| CANX | calnexin | -0.0288144 |
| RPS4X | ribosomal protein S4, X-linked | -0.0287083 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.028394 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0280117 |
| KIF4A | kinesin family member 4A | -0.0278479 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0278234 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0276791 |
| HLA-C | major histocompatibility complex, class I, C | -0.0276413 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.027323 |
| NDRG1 | N-myc downstream regulated 1 | -0.0272513 |
| SDC4 | syndecan 4 | -0.0270151 |
| MAP4 | microtubule-associated protein 4 | -0.0269593 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0266628 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0264682 |
| RPL19 | ribosomal protein L19 | -0.0259886 |
| SRGN | serglycin | -0.0259289 |
| FTL | ferritin, light polypeptide | -0.0258771 |
| CD63 | CD63 molecule | -0.0257669 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0256412 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0254791 |
| CENPF | centromere protein F, 350/400kDa | -0.0253302 |
| LOXL2 | lysyl oxidase-like 2 | -0.0252634 |
| SPAG9 | sperm associated antigen 9 | -0.0252569 |
| PRELID2 | PRELI domain containing 2 | -0.0250966 |
| AFDN | afadin, adherens junction formation factor | -0.0249787 |
| APP | amyloid beta (A4) precursor protein | -0.0249132 |
| RNF213 | ring finger protein 213 | -0.0246662 |
| DENND5A | DENN/MADD domain containing 5A | -0.0244982 |
| THBS2 | thrombospondin 2 | -0.024204 |
| RAI1 | retinoic acid induced 1 | -0.0241185 |
| ACTG1 | actin gamma 1 | -0.0233629 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0232861 |
| RPL11 | ribosomal protein L11 | -0.0229511 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0228623 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0227893 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0227543 |
| DIAPH3 | diaphanous-related formin 3 | -0.0227217 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0223517 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0219662 |
| CAVIN1 | caveolae associated protein 1 | -0.0218803 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0218504 |
| TPX2 | TPX2, microtubule-associated | -0.0217132 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0216639 |
| RPS21 | ribosomal protein S21 | -0.0215401 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0215324 |
