| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | BI-78D3 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the BI-78D3_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.146429 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.087004 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0777027 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0726877 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0692724 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0671525 |
| B2M | beta-2-microglobulin | 0.0656091 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0635896 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0609395 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0560814 |
| MAP1B | microtubule-associated protein 1B | 0.0552445 |
| FN1 | fibronectin 1 | 0.0538936 |
| FAM13A | family with sequence similarity 13, member A | 0.0522142 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0507618 |
| ZNF395 | zinc finger protein 395 | 0.0501912 |
| CD44 | CD44 molecule (Indian blood group) | 0.0498842 |
| ARRDC3 | arrestin domain containing 3 | 0.044387 |
| STC1 | stanniocalcin 1 | 0.0435758 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0414595 |
| MT2A | metallothionein 2A | 0.0410078 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0407026 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0394552 |
| PKM | pyruvate kinase, muscle | 0.0388166 |
| ATP13A3 | ATPase type 13A3 | 0.0386729 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0379984 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0371046 |
| CALD1 | caldesmon 1 | 0.037093 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0357633 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.034067 |
| MYO10 | myosin X | 0.0336169 |
| LDHA | lactate dehydrogenase A | 0.033192 |
| IL6ST | interleukin 6 signal transducer | 0.0330441 |
| MSN | moesin | 0.0326915 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0325637 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0322656 |
| IL6 | interleukin 6 | 0.0313317 |
| FRMD6 | FERM domain containing 6 | 0.0305248 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0304169 |
| KYNU | kynureninase | 0.0304031 |
| SMAD3 | SMAD family member 3 | 0.0303302 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0301554 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0294576 |
| TNS3 | tensin 3 | 0.0292345 |
| VEGFC | vascular endothelial growth factor C | 0.0289815 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0288701 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0286768 |
| GOLGA4 | golgin A4 | 0.0279574 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0275279 |
| ANXA2 | annexin A2 | 0.0274589 |
| CDK6 | cyclin-dependent kinase 6 | 0.0269121 |
| MATR3 | matrin 3 | 0.0259037 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0258228 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0256599 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0254417 |
| MEF2A | myocyte enhancer factor 2A | 0.0253989 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0251894 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0251484 |
| NAV1 | neuron navigator 1 | 0.0245729 |
| RTN4 | reticulon 4 | 0.024528 |
| LOX | lysyl oxidase | 0.0244862 |
| COL1A2 | collagen, type I, alpha 2 | 0.0244693 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0243524 |
| ANO6 | anoctamin 6 | 0.0240008 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0238488 |
| GLIS3 | GLIS family zinc finger 3 | 0.0237875 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0234989 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0233391 |
| RUNX1 | runt-related transcription factor 1 | 0.0231495 |
| CALU | calumenin | 0.0231397 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.023123 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0228997 |
| LOXL2 | lysyl oxidase-like 2 | 0.0226843 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0226285 |
| JUN | jun proto-oncogene | 0.0225555 |
| SERINC3 | serine incorporator 3 | 0.0220796 |
| RLF | rearranged L-myc fusion | 0.0218653 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0216504 |
| SYNJ2 | synaptojanin 2 | 0.0215749 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0215585 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0211386 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0211131 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0209898 |
| NRXN3 | neurexin 3 | 0.0209118 |
| FAT1 | FAT atypical cadherin 1 | 0.0207733 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0207328 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0205963 |
| ENO1 | enolase 1, (alpha) | 0.0202107 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0201482 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0196189 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0193455 |
| MYO1E | myosin IE | 0.0191871 |
| AUTS2 | autism susceptibility candidate 2 | 0.0191651 |
| RND3 | Rho family GTPase 3 | 0.0191372 |
| RNF145 | ring finger protein 145 | 0.0190399 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0188799 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0188741 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0187145 |
| AFF4 | AF4/FMR2 family, member 4 | 0.018696 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0185282 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0183672 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.0695511 |
| PTMA | prothymosin, alpha | -0.0563099 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0560946 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0534886 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0385504 |
| VIM | vimentin | -0.0317535 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0315532 |
| FTL | ferritin, light polypeptide | -0.0285482 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.026857 |
| RRBP1 | ribosome binding protein 1 | -0.0251403 |
| S100A10 | S100 calcium binding protein A10 | -0.0249216 |
| HM13 | histocompatibility (minor) 13 | -0.0246099 |
| COL1A1 | collagen, type I, alpha 1 | -0.0234736 |
| RPS23 | ribosomal protein S23 | -0.02281 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.020959 |
| CAVIN1 | caveolae associated protein 1 | -0.0199499 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0195407 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0194181 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.018239 |
| RPL19 | ribosomal protein L19 | -0.0178111 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0176542 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0176218 |
| RPS13 | ribosomal protein S13 | -0.0175989 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0173751 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0171711 |
| RPLP1 | ribosomal protein, large, P1 | -0.0170502 |
| RPL37 | ribosomal protein L37 | -0.0168107 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0167741 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0164032 |
| THOC2 | THO complex 2 | -0.0160915 |
| NKTR | natural killer cell triggering receptor | -0.0159325 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0158269 |
| RPL27A | ribosomal protein L27a | -0.0157464 |
| TPM4 | tropomyosin 4 | -0.0157166 |
| RPL31 | ribosomal protein L31 | -0.0150312 |
| TMSB10 | thymosin beta 10 | -0.0149896 |
| OGA | O-GlcNAcase | -0.0148659 |
| RPL35A | ribosomal protein L35a | -0.014676 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0146701 |
| MAP4 | microtubule-associated protein 4 | -0.0146259 |
| HLA-C | major histocompatibility complex, class I, C | -0.0146052 |
| TMEM41B | transmembrane protein 41B | -0.0143795 |
| AOPEP | aminopeptidase O (putative) | -0.0143611 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.014178 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0141593 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0140593 |
| TBCA | tubulin folding cofactor A | -0.0138975 |
| LMNA | lamin A/C | -0.0138649 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0137386 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0136307 |
| COL5A1 | collagen, type V, alpha 1 | -0.0134414 |
| SELENOK | selenoprotein K | -0.0130484 |
| SNX14 | sorting nexin 14 | -0.0128054 |
| RPS24 | ribosomal protein S24 | -0.0126303 |
| AEBP2 | AE binding protein 2 | -0.0125669 |
| RPS3 | ribosomal protein S3 | -0.0125648 |
| PCNX4 | pecanex 4 | -0.0125531 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0125108 |
| FLOT1 | flotillin 1 | -0.0124591 |
| SRBD1 | S1 RNA binding domain 1 | -0.0123883 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0123805 |
| NOP56 | NOP56 ribonucleoprotein | -0.0123694 |
| VCP | valosin containing protein | -0.0123133 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | -0.0122961 |
| TNPO1 | transportin 1 | -0.0122705 |
| FNBP4 | formin binding protein 4 | -0.0122483 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0122392 |
| STC2 | stanniocalcin 2 | -0.0121515 |
| RPL13A | ribosomal protein L13a | -0.012146 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0120903 |
| RPS29 | ribosomal protein S29 | -0.0120735 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0120605 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0120395 |
| AK1 | adenylate kinase 1 | -0.0118555 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0118421 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0117402 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0117095 |
| COG5 | component of oligomeric golgi complex 5 | -0.0116449 |
| CEP290 | centrosomal protein 290kDa | -0.01164 |
| PUM3 | pumilio RNA binding family member 3 | -0.0116075 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0115675 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0114671 |
| POTEF | POTE ankyrin domain family, member F | -0.0114252 |
| NUP98 | nucleoporin 98kDa | -0.0113731 |
| SHLD2 | shieldin complex subunit 2 | -0.0113319 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0112975 |
| XPOT | exportin, tRNA | -0.0112699 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0112651 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0112363 |
| GPR173 | G protein-coupled receptor 173 | -0.0111805 |
| RPL38 | ribosomal protein L38 | -0.0110947 |
| TMEM14B | transmembrane protein 14B | -0.0110791 |
| PHKB | phosphorylase kinase, beta | -0.0109386 |
| RPS8 | ribosomal protein S8 | -0.0108904 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | -0.0108386 |
| SPAG16 | sperm associated antigen 16 | -0.0107782 |
| CFAP73 | cilia and flagella associated protein 73 | -0.0106399 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -0.0105959 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0105598 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0105461 |
