| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | BI-78D3 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the BI-78D3_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0527378 |
| FNDC3B | fibronectin type III domain containing 3B | 0.050464 |
| FNIP1 | folliculin interacting protein 1 | 0.0456363 |
| ASPH | aspartate beta-hydroxylase | 0.038367 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0379165 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0349483 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0339892 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0330963 |
| DST | dystonin | 0.0328217 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0313434 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0309135 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0304806 |
| GOLGB1 | golgin B1 | 0.0297612 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0291938 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0277074 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0274248 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0272347 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0271122 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.026254 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0260317 |
| SMAD3 | SMAD family member 3 | 0.0257091 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0255763 |
| YEATS2 | YEATS domain containing 2 | 0.0251221 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0249072 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0247021 |
| SMYD3 | SET and MYND domain containing 3 | 0.0244195 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0243015 |
| ANO6 | anoctamin 6 | 0.0242795 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0240038 |
| INTS6 | integrator complex subunit 6 | 0.0237354 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0235291 |
| SON | SON DNA binding protein | 0.0230738 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0228876 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0228191 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0227498 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0221174 |
| ATXN1 | ataxin 1 | 0.0219494 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0219016 |
| CUL5 | cullin 5 | 0.0215809 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.021177 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0211453 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0209878 |
| ADIPOR2 | adiponectin receptor 2 | 0.0209333 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0209046 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0205475 |
| ITGAV | integrin, alpha V | 0.0203267 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0203011 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0200348 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0198972 |
| MEF2A | myocyte enhancer factor 2A | 0.0198695 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.019839 |
| GPC5 | glypican 5 | 0.019779 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0197644 |
| TES | testin LIM domain protein | 0.0196613 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0196317 |
| PKM | pyruvate kinase, muscle | 0.0194519 |
| MAP1B | microtubule-associated protein 1B | 0.0193003 |
| ARCN1 | archain 1 | 0.0191538 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0190841 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | 0.0189795 |
| PRKCA | protein kinase C, alpha | 0.0187887 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0187551 |
| RAD51B | RAD51 paralog B | 0.0186505 |
| TRAM2 | translocation associated membrane protein 2 | 0.0186478 |
| JUN | jun proto-oncogene | 0.0183416 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0182105 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0180949 |
| KLF12 | Kruppel-like factor 12 | 0.0179382 |
| PCDH7 | protocadherin 7 | 0.0178654 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0178643 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0177012 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0173858 |
| SBF2 | SET binding factor 2 | 0.0173719 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0173298 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0170311 |
| XPOT | exportin, tRNA | 0.0170303 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0169794 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.016909 |
| USP34 | ubiquitin specific peptidase 34 | 0.0168457 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0168352 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0168144 |
| CCDC50 | coiled-coil domain containing 50 | 0.0167831 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0167018 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0166893 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0166327 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0165145 |
| MATR3 | matrin 3 | 0.0164431 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0164369 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0163853 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.0163439 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0162778 |
| FLNB | filamin B, beta | 0.0162281 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0161238 |
| PTK2 | protein tyrosine kinase 2 | 0.0160657 |
| TXNRD1 | thioredoxin reductase 1 | 0.0160499 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0160464 |
| RPL23 | ribosomal protein L23 | 0.0160302 |
| ATP13A3 | ATPase type 13A3 | 0.0160191 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0159818 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | 0.0157845 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.295346 |
| VIM | vimentin | -0.0745947 |
| PTMA | prothymosin, alpha | -0.0706541 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0684288 |
| MT2A | metallothionein 2A | -0.0622896 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0621041 |
| RPLP1 | ribosomal protein, large, P1 | -0.0538247 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0517618 |
| CANX | calnexin | -0.0458499 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0457906 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0437392 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0427391 |
| SPAG9 | sperm associated antigen 9 | -0.041444 |
| GNAS | GNAS complex locus | -0.040669 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0403447 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0403262 |
| SETD5 | SET domain containing 5 | -0.0396979 |
| FTL | ferritin, light polypeptide | -0.0392045 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0373314 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0342336 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0336016 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0327728 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.032716 |
| ANXA2 | annexin A2 | -0.0313902 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0303124 |
| YBX3 | Y box binding protein 3 | -0.0297239 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0290662 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0284849 |
| GOLGA4 | golgin A4 | -0.0282604 |
| SEPTIN7 | septin 7 | -0.0281833 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0281783 |
| IER3 | immediate early response 3 | -0.0280994 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0275058 |
| RPS29 | ribosomal protein S29 | -0.0274988 |
| POTEF | POTE ankyrin domain family, member F | -0.026801 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0267896 |
| RPL12 | ribosomal protein L12 | -0.0266733 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0263158 |
| NLK | nemo-like kinase | -0.0262798 |
| SDC4 | syndecan 4 | -0.0262774 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0261922 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0257067 |
| RPL4 | ribosomal protein L4 | -0.0256973 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0256654 |
| MORF4L2 | mortality factor 4 like 2 | -0.025663 |
| RPL9 | ribosomal protein L9 | -0.025509 |
| RPL15 | ribosomal protein L15 | -0.0253583 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0253207 |
| TPX2 | TPX2, microtubule-associated | -0.0249204 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0248592 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0247701 |
| FUS | FUS RNA binding protein | -0.0246861 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0246433 |
| WDR45B | WD repeat domain 45B | -0.0240496 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0238902 |
| CAVIN1 | caveolae associated protein 1 | -0.0233947 |
| CALU | calumenin | -0.023344 |
| PFN1 | profilin 1 | -0.0231754 |
| FMNL2 | formin-like 2 | -0.0229334 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0226827 |
| OGA | O-GlcNAcase | -0.0226628 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0226025 |
| RBM39 | RNA binding motif protein 39 | -0.0225838 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0225177 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.0224103 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.022097 |
| BSG | basigin (Ok blood group) | -0.0219299 |
| KIF5B | kinesin family member 5B | -0.0218925 |
| RPS8 | ribosomal protein S8 | -0.0216742 |
| RPS13 | ribosomal protein S13 | -0.0216563 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0211207 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0210097 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0208797 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0208174 |
| PARD3 | par-3 family cell polarity regulator | -0.0207045 |
| IGF2 | insulin-like growth factor 2 | -0.0206299 |
| RPL7A | ribosomal protein L7a | -0.0206216 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0205447 |
| NCKAP1 | NCK-associated protein 1 | -0.0205288 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0204286 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | -0.0199359 |
| RPL11 | ribosomal protein L11 | -0.0197273 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0194407 |
| TMSB10 | thymosin beta 10 | -0.0192933 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0192869 |
| TAOK3 | TAO kinase 3 | -0.0191931 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0191223 |
| RPS6 | ribosomal protein S6 | -0.0190751 |
| RPL32 | ribosomal protein L32 | -0.0190688 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.019036 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0189469 |
| YTHDC1 | YTH domain containing 1 | -0.0186963 |
| PDS5B | PDS5 cohesin associated factor B | -0.0184598 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0184081 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.0183694 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.018088 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0180497 |
| RNF213 | ring finger protein 213 | -0.0179737 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0178332 |
| RPS15 | ribosomal protein S15 | -0.0178177 |
