| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | BI-78D3 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the BI-78D3_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.106143 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.06854 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0545167 |
| PTMA | prothymosin, alpha | 0.0503194 |
| INTS6 | integrator complex subunit 6 | 0.0482527 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0402322 |
| ASPH | aspartate beta-hydroxylase | 0.0386323 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0374846 |
| VCL | vinculin | 0.0326202 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0296424 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0289519 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0267811 |
| FNDC3B | fibronectin type III domain containing 3B | 0.026547 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0245218 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0244899 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0243424 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0241849 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0235662 |
| RAB10 | RAB10, member RAS oncogene family | 0.0233734 |
| RPS6 | ribosomal protein S6 | 0.022992 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0228495 |
| CANX | calnexin | 0.02271 |
| ATF6 | activating transcription factor 6 | 0.022441 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0215135 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0214638 |
| GOLGB1 | golgin B1 | 0.0209929 |
| MCL1 | myeloid cell leukemia 1 | 0.020854 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0202815 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0194009 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0193908 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0190168 |
| LRRC23 | leucine rich repeat containing 23 | 0.0189626 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0186155 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.018254 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0182027 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0178321 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0176636 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0174957 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.017457 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0172954 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0172418 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0169668 |
| CTBP2 | C-terminal binding protein 2 | 0.0166526 |
| RPS25 | ribosomal protein S25 | 0.0166394 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0164867 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0163267 |
| ACTG1 | actin gamma 1 | 0.0161401 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | 0.0159416 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0159363 |
| RPL37A | ribosomal protein L37a | 0.0158939 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0158098 |
| AEBP2 | AE binding protein 2 | 0.015781 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0157584 |
| RPS12 | ribosomal protein S12 | 0.0154126 |
| GOLGA4 | golgin A4 | 0.015409 |
| PKM | pyruvate kinase, muscle | 0.0153273 |
| FBXO11 | F-box protein 11 | 0.0151668 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0150659 |
| RCOR1 | REST corepressor 1 | 0.0150639 |
| GPC6 | glypican 6 | 0.0149502 |
| MYO1E | myosin IE | 0.0148472 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0147374 |
| GPATCH2L | G patch domain containing 2-like | 0.0147344 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0146751 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0145999 |
| IER3 | immediate early response 3 | 0.0144415 |
| RPL23 | ribosomal protein L23 | 0.01429 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.01424 |
| RPS11 | ribosomal protein S11 | 0.0142233 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0137178 |
| ANXA2 | annexin A2 | 0.0136184 |
| RPS23 | ribosomal protein S23 | 0.0135116 |
| RPS24 | ribosomal protein S24 | 0.0134236 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0133209 |
| RPL31 | ribosomal protein L31 | 0.0132755 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0131406 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.013084 |
| NXN | nucleoredoxin | 0.0128861 |
| RPL9 | ribosomal protein L9 | 0.0128147 |
| SEPTIN9 | septin 9 | 0.0127815 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0127617 |
| RAD51B | RAD51 paralog B | 0.0127308 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0126937 |
| TUFT1 | tuftelin 1 | 0.0126629 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0126569 |
| RUNX1 | runt-related transcription factor 1 | 0.0126546 |
| CADM1 | cell adhesion molecule 1 | 0.0126462 |
| SIK3 | SIK family kinase 3 | 0.0126175 |
| EGR1 | early growth response 1 | 0.0126011 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0125469 |
| MORF4L2 | mortality factor 4 like 2 | 0.0125208 |
| EMP1 | epithelial membrane protein 1 | 0.0124481 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0123823 |
| ANKRD11 | ankyrin repeat domain 11 | 0.012094 |
| PTGES2 | prostaglandin E synthase 2 | 0.0120408 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0119247 |
| MTDH | metadherin | 0.011866 |
| SFTPA2 | surfactant protein A2 | 0.0117712 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0117522 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0117462 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.138898 |
| FN1 | fibronectin 1 | -0.125086 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.118991 |
| ITGA1 | integrin, alpha 1 | -0.0626626 |
| HMGA2 | high mobility group AT-hook 2 | -0.0600966 |
| NRG1 | neuregulin 1 | -0.0470722 |
| TMEM156 | transmembrane protein 156 | -0.0463718 |
| KLHL5 | kelch-like family member 5 | -0.0317287 |
| OSMR | oncostatin M receptor | -0.028814 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0283549 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0254416 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0238343 |
| SYT1 | synaptotagmin I | -0.0232768 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0227234 |
| ETV1 | ets variant 1 | -0.0209871 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0201902 |
| GLIS3 | GLIS family zinc finger 3 | -0.0200286 |
| SQSTM1 | sequestosome 1 | -0.01948 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0189123 |
| NRP1 | neuropilin 1 | -0.0186062 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0169648 |
| TMEM165 | transmembrane protein 165 | -0.0166507 |
| TMSB4X | thymosin beta 4, X-linked | -0.0166309 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0165156 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0162319 |
| RUNX2 | runt-related transcription factor 2 | -0.0157859 |
| RAI14 | retinoic acid induced 14 | -0.0157267 |
| TMSB10 | thymosin beta 10 | -0.0152908 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0152192 |
| AOPEP | aminopeptidase O (putative) | -0.015156 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0150585 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0150269 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0148266 |
| SMOX | spermine oxidase | -0.0144814 |
| TNS3 | tensin 3 | -0.0144303 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0142898 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0142139 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0139038 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0139013 |
| PELO | pelota homolog (Drosophila) | -0.0130203 |
| EFNA5 | ephrin-A5 | -0.0129488 |
| ETV6 | ets variant 6 | -0.0127523 |
| FAM20C | family with sequence similarity 20, member C | -0.0126282 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0125801 |
| S100A6 | S100 calcium binding protein A6 | -0.012567 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0123262 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0121625 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.012016 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0117463 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.0116853 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0114448 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0114278 |
| RBM25 | RNA binding motif protein 25 | -0.0113579 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.011343 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0112471 |
| ITGB5 | integrin, beta 5 | -0.0111955 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0109793 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0109194 |
| RTN4 | reticulon 4 | -0.010889 |
| AHR | aryl hydrocarbon receptor | -0.0106787 |
| DUSP6 | dual specificity phosphatase 6 | -0.0105195 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.00999116 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.00986865 |
| FAF2 | Fas associated factor family member 2 | -0.00972604 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | -0.00969989 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.00960579 |
| FNBP1 | formin binding protein 1 | -0.00957031 |
| VEGFA | vascular endothelial growth factor A | -0.00938337 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.00933662 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.00913752 |
| ATXN10 | ataxin 10 | -0.00902261 |
| FBN1 | fibrillin 1 | -0.00901383 |
| TGFB2 | transforming growth factor, beta 2 | -0.00900058 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.00898622 |
| LMNA | lamin A/C | -0.00880694 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.00876599 |
| CFB | complement factor B | -0.00873429 |
| CP | ceruloplasmin (ferroxidase) | -0.00871878 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.00858593 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.00847918 |
| LIFR | leukemia inhibitory factor receptor alpha | -0.00842887 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00833588 |
| TGFA | transforming growth factor, alpha | -0.008322 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.00822189 |
| ADD3 | adducin 3 (gamma) | -0.0082094 |
| CCNJL | cyclin J-like | -0.0081478 |
| SON | SON DNA binding protein | -0.00814421 |
| SYNJ2 | synaptojanin 2 | -0.00800349 |
| CAB39 | calcium binding protein 39 | -0.00798839 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00798602 |
| ANTXR2 | anthrax toxin receptor 2 | -0.00791067 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.00787411 |
| AHI1 | Abelson helper integration site 1 | -0.00782189 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0078175 |
| NEMF | nuclear export mediator factor | -0.00777164 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00773445 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.00772931 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.00772877 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.00765706 |
| PLAUR | plasminogen activator, urokinase receptor | -0.00756556 |
