BID Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description BH3 interacting domain death agonist|This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 637)
External Link https://ncbi.nlm.nih.gov/gene/637
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Genes

499 genes differentially expressed following the BID gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0164694
SSBP2 single-stranded DNA binding protein 2 0.0163533
SLPI secretory leukocyte peptidase inhibitor 0.0162295
TACSTD2 tumor-associated calcium signal transducer 2 0.014856
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0144674
S100A9 S100 calcium binding protein A9 0.0141067
CSTA cystatin A (stefin A) 0.0139055
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.0138273
LCN2 lipocalin 2 0.013717
HSPA1A heat shock 70kDa protein 1A 0.0135039
IL1RN interleukin 1 receptor antagonist 0.0131764
LTF lactotransferrin 0.0123662
CCL20 chemokine (C-C motif) ligand 20 0.0123007
MMP7 matrix metallopeptidase 7 0.0120294
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.0116617
BAMBI BMP and activin membrane-bound inhibitor 0.011212
DEFB1 defensin, beta 1 0.0107941
CLDN10 claudin 10 0.0107913
AKR1C3 aldo-keto reductase family 1, member C3 0.010777
NIBAN1 niban apoptosis regulator 1 0.0106762
CXCL8 chemokine (C-X-C motif) ligand 8 0.0104813
S100P S100 calcium binding protein P 0.0104791
CXCL5 chemokine (C-X-C motif) ligand 5 0.0104667
MAL mal, T-cell differentiation protein 0.0103595
RNF167 ring finger protein 167 0.0103538
OXTR oxytocin receptor 0.0103472
BASP1 brain abundant, membrane attached signal protein 1 0.0103007
S100A8 S100 calcium binding protein A8 0.0102238
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.0101915
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0101448
MSMB microseminoprotein, beta- 0.0100905
MLF1 myeloid leukemia factor 1 0.00998532
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00997748
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00970802
PI3 peptidase inhibitor 3, skin-derived 0.00964321
PITX3 paired-like homeodomain 3 0.00956902
PDZK1IP1 PDZK1 interacting protein 1 0.00954091
TM4SF1 transmembrane 4 L six family member 1 0.0094093
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.00939948
CALB1 calbindin 1, 28kDa 0.0093693
KRT13 keratin 13, type I 0.00932498
SPRR3 small proline-rich protein 3 0.00930201
PRAME preferentially expressed antigen in melanoma 0.00925047
FXYD3 FXYD domain containing ion transport regulator 3 0.00920977
SCEL sciellin 0.00920704
ABHD4 abhydrolase domain containing 4 0.00917853
BPGM 2,3-bisphosphoglycerate mutase 0.00907991
KRT15 keratin 15, type I 0.00907972
KRT6A keratin 6A, type II 0.00903654
PLBD1 phospholipase B domain containing 1 0.00903157
AQP3 aquaporin 3 (Gill blood group) 0.00900412
EYA2 EYA transcriptional coactivator and phosphatase 2 0.00897121
NEU1 sialidase 1 (lysosomal sialidase) 0.00896459
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00884387
CRYAB crystallin, alpha B 0.00883501
CD59 CD59 molecule, complement regulatory protein 0.00879742
XIC X chromosome inactivation center 0.00879447
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.0087564
F5 coagulation factor V (proaccelerin, labile factor) 0.00873579
ACP3 acid phosphatase 3 0.00872389
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00867249
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.00866411
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00865868
CNOT4 CCR4-NOT transcription complex, subunit 4 0.00858981
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.00855895
WNT5A wingless-type MMTV integration site family, member 5A 0.00854567
TSPAN8 tetraspanin 8 0.00850999
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00844958
GABARAPL1 GABA(A) receptor-associated protein like 1 0.00836331
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.00835283
TRIM16 tripartite motif containing 16 0.00830761
EMX2 empty spiracles homeobox 2 0.0082611
HHLA3 HERV-H LTR-associating 3 0.00823815
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00819431
CRISP3 cysteine-rich secretory protein 3 0.0081731
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00817112
NDP Norrie disease (pseudoglioma) 0.00813478
IQCG IQ motif containing G 0.00808413
RBKS ribokinase 0.0080756
PSAP prosaposin 0.00807292
STK38L serine/threonine kinase 38 like 0.00795233
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00794831
TSPAN1 tetraspanin 1 0.00792728
MVP major vault protein 0.00790011
ATXN1 ataxin 1 0.00788869
NME5 NME/NM23 family member 5 0.00782734
BCL2A1 BCL2-related protein A1 0.00773929
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.00773129
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.00767342
FOLR1 folate receptor 1 (adult) 0.00765965
GSTP1 glutathione S-transferase pi 1 0.00763628
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00761168
VLDLR very low density lipoprotein receptor 0.00761067
PARL presenilin associated, rhomboid-like 0.00755674
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00755327
HIST1H2AC histone cluster 1, H2ac 0.00754805
TNIP1 TNFAIP3 interacting protein 1 0.00754687
KYNU kynureninase 0.00752271
KRT5 keratin 5, type II 0.00751774
LGALS3 lectin, galactoside-binding, soluble, 3 0.00749707
FOSL2 FOS-like antigen 2 0.00747536
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00746131
GPX3 glutathione peroxidase 3 0.00744034
SNAP25 synaptosomal-associated protein, 25kDa 0.00742255
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.00738961
RRAS related RAS viral (r-ras) oncogene homolog 0.00738454
C6ORF48 chromosome 6 open reading frame 48 0.00737022
RWDD2A RWD domain containing 2A 0.00730007
TOX thymocyte selection-associated high mobility group box 0.00729972
MT1X metallothionein 1X 0.00727936
KLK11 kallikrein-related peptidase 11 0.00726698
CHI3L2 chitinase 3-like 2 0.00725288
CXCL3 chemokine (C-X-C motif) ligand 3 0.00722375
CARMIL1 capping protein regulator and myosin 1 linker 1 0.00722199
PTHLH parathyroid hormone-like hormone 0.00720192
OPTN optineurin 0.0071686
LZTS3 leucine zipper, putative tumor suppressor family member 3 0.00715144
RRAGD Ras-related GTP binding D 0.00713464
TFPI2 tissue factor pathway inhibitor 2 0.0071252
EGR2 early growth response 2 0.00712391
MXI1 MAX interactor 1, dimerization protein 0.00710095
SLC16A4 solute carrier family 16, member 4 0.00709866
RGS20 regulator of G-protein signaling 20 0.00708936
S100A11 S100 calcium binding protein A11 0.0070824
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00707178
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00706237
KLK10 kallikrein-related peptidase 10 0.00705523
GREB1 growth regulation by estrogen in breast cancer 1 0.00703494
SH3GL2 SH3-domain GRB2-like 2 0.00703035
ZIC1 Zic family member 1 0.00701535
PGD phosphogluconate dehydrogenase 0.00699312
S100A12 S100 calcium binding protein A12 0.00698721
MAP9 microtubule-associated protein 9 0.00696737
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00696338
ANXA1 annexin A1 0.00694134
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00690632
YPEL5 yippee-like 5 (Drosophila) 0.00689056
ZNF185 zinc finger protein 185 (LIM domain) 0.00688979
LAMC2 laminin, gamma 2 0.00688546
LOC730101 uncharacterized LOC730101 0.00687994
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.00686436
CCDC176 coiled-coil domain containing 176 0.00683716
ZNF277 zinc finger protein 277 0.00683571
SLC25A46 solute carrier family 25, member 46 0.0068341
MMP1 matrix metallopeptidase 1 0.00683236
PLIN3 perilipin 3 0.00680247
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.00679372
TREM1 triggering receptor expressed on myeloid cells 1 0.00678906
KRT14 keratin 14, type I 0.00678121
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.00677539
PITX1 paired-like homeodomain 1 0.00676055
AK4 adenylate kinase 4 0.00673845
TUBB2A tubulin, beta 2A class IIa 0.00673448
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00672461
ZNF410 zinc finger protein 410 0.00672303
NKX3-1 NK3 homeobox 1 0.00672131
TNF tumor necrosis factor 0.00670954
GM2A GM2 ganglioside activator 0.0067082
QPCT glutaminyl-peptide cyclotransferase 0.00669583
SPRR1B small proline-rich protein 1B 0.00668872
PLCB4 phospholipase C, beta 4 0.00668596
TRIM38 tripartite motif containing 38 0.00665377
GSDME gasdermin E 0.00665162
ATF3 activating transcription factor 3 0.0066496
FBXO11 F-box protein 11 0.00664915
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00663937
ANXA2P2 annexin A2 pseudogene 2 0.0066337
COG5 component of oligomeric golgi complex 5 0.00662315
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.00660555
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.00660523
RHCG Rh family, C glycoprotein 0.00659807
GRN granulin 0.00657527
SOSTDC1 sclerostin domain containing 1 0.00657383
AKR1C2 aldo-keto reductase family 1, member C2 0.00656883
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.00654334
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00652321
IL33R interleukin 33 receptor 0.0065014
S100A2 S100 calcium binding protein A2 0.0064829
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.00647971
CETN2 centrin, EF-hand protein, 2 0.00646141
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00644733
FGF2 fibroblast growth factor 2 (basic) 0.00644029
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00643289
IFI27 interferon, alpha-inducible protein 27 0.00643278
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00642845
FOXG1 forkhead box G1 0.00642118
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.00642105
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00641111
TTC30A tetratricopeptide repeat domain 30A 0.00636932
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.00635043
ANXA11 annexin A11 0.00634565
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 0.00634227
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.00632994
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00632589
CAPG capping protein (actin filament), gelsolin-like 0.00629485
AKAP12 A kinase (PRKA) anchor protein 12 0.00629236
RIT1 Ras-like without CAAX 1 0.00628575
BTG2 BTG family, member 2 0.00627619
CRIPT cysteine-rich PDZ-binding protein 0.00627398
NRCAM neuronal cell adhesion molecule 0.00620698
TPM4 tropomyosin 4 0.00619798
NUPR1 nuclear protein, transcriptional regulator, 1 0.00619128
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.00617467
LPAR6 lysophosphatidic acid receptor 6 0.00617382
NPR3 natriuretic peptide receptor 3 0.00613755
SEC13 SEC13 homolog (S. cerevisiae) 0.00612973
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.00612937
PELI2 pellino E3 ubiquitin protein ligase family member 2 0.00612379
CTSC cathepsin C 0.00611253
MAOB monoamine oxidase B 0.00609522
COG7 component of oligomeric golgi complex 7 0.0060879
IFT20 intraflagellar transport 20 0.00608545
TMEM242 transmembrane protein 242 0.00608081
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.00606239
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.00605049
DSP desmoplakin 0.00604865
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 0.00604661
MSLN mesothelin 0.00603734
ZBED8 zinc finger, BED-type containing 8 0.00602273
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 0.0060105
TKTL1 transketolase-like 1 0.00600689
UPK1B uroplakin 1B 0.00600136
CYB5A cytochrome b5 type A (microsomal) 0.00599409
RPP40 ribonuclease P/MRP 40kDa subunit 0.00598545
KL klotho 0.00598365
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00597467
GCLC glutamate-cysteine ligase, catalytic subunit 0.00597361
ORC5 origin recognition complex, subunit 5 0.00597183
ANKRD6 ankyrin repeat domain 6 0.00596031
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.00595036
AGTPBP1 ATP/GTP binding protein 1 0.00594923
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 0.00594819
CRTAM cytotoxic and regulatory T cell molecule 0.00593158
RABAC1 Rab acceptor 1 (prenylated) 0.00592466
SASH3 SAM and SH3 domain containing 3 0.00591604
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.00591112
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00590731
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 0.0059011
RPL23AP7 ribosomal protein L23a pseudogene 7 0.00589879
CROT carnitine O-octanoyltransferase 0.00589786
SFRP1 secreted frizzled-related protein 1 0.00589781
TPD52L1 tumor protein D52-like 1 0.00589626
IL1A interleukin 1, alpha 0.00588272
CPD carboxypeptidase D 0.00587643
SELL selectin L 0.00587335
CXCL2 chemokine (C-X-C motif) ligand 2 0.0058521
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00584876
ARL8B ADP-ribosylation factor-like 8B 0.00584721
BUD31 BUD31 homolog (S. cerevisiae) 0.00584712
IL1B interleukin 1, beta 0.00583932

decreased expression

Symbol Name Standardized Value
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0234415
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.01656
MAP7 microtubule-associated protein 7 -0.0133514
FRZB frizzled-related protein -0.0123223
ASPN asporin -0.0119501
SDC1 syndecan 1 -0.0117366
CA2 carbonic anhydrase II -0.0117116
COL6A2 collagen, type VI, alpha 2 -0.010883
MXRA8 matrix-remodelling associated 8 -0.0107035
TFF3 trefoil factor 3 (intestinal) -0.0105765
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.0105476
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.0104389
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.0102668
LXN latexin -0.0102506
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0101283
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0101243
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.0101023
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.0100045
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00990806
TSPAN13 tetraspanin 13 -0.00966338
SLC38A1 solute carrier family 38, member 1 -0.00956177
PRDX2 peroxiredoxin 2 -0.00951665
COL10A1 collagen, type X, alpha 1 -0.00948416
LRRC15 leucine rich repeat containing 15 -0.00941818
SEPP1 selenoprotein P, plasma, 1 -0.00934392
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00929221
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00927228
CD36 CD36 molecule (thrombospondin receptor) -0.00925013
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00916993
FASN fatty acid synthase -0.00916287
SNAI2 snail family zinc finger 2 -0.00907918
COMP cartilage oligomeric matrix protein -0.00901962
ADGRF5 adhesion G protein-coupled receptor F5 -0.00901814
PCOLCE procollagen C-endopeptidase enhancer -0.00900014
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0089999
TARDBP TAR DNA binding protein -0.00896015
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -0.00888626
LAMP5 lysosomal-associated membrane protein family, member 5 -0.00887793
MFAP2 microfibrillar-associated protein 2 -0.0088717
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00885351
CDC20 cell division cycle 20 -0.00883995
FABP4 fatty acid binding protein 4, adipocyte -0.00882744
AEBP1 AE binding protein 1 -0.00875659
NID2 nidogen 2 (osteonidogen) -0.00869366
HNRNPL heterogeneous nuclear ribonucleoprotein L -0.0086646
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -0.00862704
RTN2 reticulon 2 -0.00846242
ANKRD10 ankyrin repeat domain 10 -0.00845609
BGN biglycan -0.0083901
HOXD1 homeobox D1 -0.00832484
SPRY2 sprouty homolog 2 (Drosophila) -0.00820782
ANGPTL2 angiopoietin-like 2 -0.00815085
KIF14 kinesin family member 14 -0.00813492
TAGLN transgelin -0.00810631
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.00810093
JCHAIN joining chain of multimeric IgA and IgM -0.00809329
MMP11 matrix metallopeptidase 11 -0.00807286
MUC2 mucin 2, oligomeric mucus/gel-forming -0.00805346
SPRY4 sprouty homolog 4 (Drosophila) -0.00803821
CLEC2B C-type lectin domain family 2, member B -0.00802607
FSTL1 follistatin-like 1 -0.00801785
ISYNA1 inositol-3-phosphate synthase 1 -0.00797126
METRN meteorin, glial cell differentiation regulator -0.00796664
OIP5 Opa interacting protein 5 -0.00796376
CFD complement factor D (adipsin) -0.00794384
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.00783332
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00782529
LMNB1 lamin B1 -0.00781336
RAPSN receptor-associated protein of the synapse -0.00775366
COL3A1 collagen, type III, alpha 1 -0.00772749
FANCG Fanconi anemia, complementation group G -0.00764648
CDCA4 cell division cycle associated 4 -0.00762608
LY6E lymphocyte antigen 6 complex, locus E -0.00758632
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00757112
GREM1 gremlin 1, DAN family BMP antagonist -0.00756209
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.0074966
GAS1 growth arrest-specific 1 -0.00746664
TPSAB1 tryptase alpha/beta 1 -0.00743716
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.00736097
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00734476
TPBG trophoblast glycoprotein -0.00732738
OLFM1 olfactomedin 1 -0.00728818
HELLS helicase, lymphoid-specific -0.00727159
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.00724562
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.00722268
RPA3 replication protein A3, 14kDa -0.00716822
KRT20 keratin 20, type I -0.0071466
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.00713281
DDR2 discoidin domain receptor tyrosine kinase 2 -0.00713065
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00713033
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00711466
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -0.00710389
TGFB3 transforming growth factor, beta 3 -0.00710225
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.00704132
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -0.00703642
GTSE1 G-2 and S-phase expressed 1 -0.00702335
RNF38 ring finger protein 38 -0.00700986
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) -0.00700541
FANCI Fanconi anemia, complementation group I -0.00698718
MXRA5 matrix-remodelling associated 5 -0.00697374
RGS5 regulator of G-protein signaling 5 -0.00697155
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00696686
IGF1 insulin-like growth factor 1 (somatomedin C) -0.00695862
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00687714
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -0.00685967
PFDN4 prefoldin subunit 4 -0.00684503
GLT8D2 glycosyltransferase 8 domain containing 2 -0.00680677
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00679991
TMEM204 transmembrane protein 204 -0.00679074
RGS16 regulator of G-protein signaling 16 -0.00678005
COL8A2 collagen, type VIII, alpha 2 -0.00677926
TNS3 tensin 3 -0.00677726
ACKR3 atypical chemokine receptor 3 -0.00676638
HMGB3 high mobility group box 3 -0.00676282
MELK maternal embryonic leucine zipper kinase -0.00672588
DHFR dihydrofolate reductase -0.00671096
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0066995
TENT4A terminal nucleotidyltransferase 4A -0.00669251
TPD52 tumor protein D52 -0.00668731
PRC1 protein regulator of cytokinesis 1 -0.00668186
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -0.00668158
COL11A1 collagen, type XI, alpha 1 -0.00667795
ZBTB18 zinc finger and BTB domain containing 18 -0.00664544
POSTN periostin, osteoblast specific factor -0.00664076
PHF10 PHD finger protein 10 -0.00663923
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -0.00663299
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) -0.00662568
PLN phospholamban -0.00659019
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.0065874
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00656486
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.0065601
CLC Charcot-Leyden crystal galectin -0.00655953
THY1 Thy-1 cell surface antigen -0.00654708
CIT citron rho-interacting serine/threonine kinase -0.00652979
CPT1A carnitine palmitoyltransferase 1A (liver) -0.00652854
SDC3 syndecan 3 -0.0065261
PBX3 pre-B-cell leukemia homeobox 3 -0.00652445
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.00651377
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.0065002
PMP22 peripheral myelin protein 22 -0.00649942
TIMELESS timeless circadian clock -0.00646588
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0064403
THBS2 thrombospondin 2 -0.00642618
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -0.00641192
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00641087
NNMT nicotinamide N-methyltransferase -0.00640185
HSPA13 heat shock protein 70kDa family, member 13 -0.00640152
STK10 serine/threonine kinase 10 -0.00639473
CTSK cathepsin K -0.00639075
ZBTB20 zinc finger and BTB domain containing 20 -0.00637195
GUCA2A guanylate cyclase activator 2A (guanylin) -0.00635651
AREG amphiregulin -0.00635043
MCM4 minichromosome maintenance complex component 4 -0.00634744
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00634666
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00632907
TXLNA taxilin alpha -0.00632482
KIF18B kinesin family member 18B -0.00630949
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.00630906
NPTX2 neuronal pentraxin II -0.00630853
C1QB complement component 1, q subcomponent, B chain -0.00627146
DPY19L1 dpy-19-like 1 (C. elegans) -0.00624201
GSE1 Gse1 coiled-coil protein -0.00623092
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 -0.00622492
FBXW12 F-box and WD repeat domain containing 12 -0.00621973
PCGF3 polycomb group ring finger 3 -0.00620968
MMP2 matrix metallopeptidase 2 -0.00619605
CCL11 chemokine (C-C motif) ligand 11 -0.00617757
GPAA1 glycosylphosphatidylinositol anchor attachment 1 -0.00617751
KDM5D lysine (K)-specific demethylase 5D -0.00617328
RAP1GAP RAP1 GTPase activating protein -0.0061657
METTL7A methyltransferase like 7A -0.00616482
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.00615968
ADIRF adipogenesis regulatory factor -0.00615471
GRAMD4 GRAM domain containing 4 -0.00614597
ELN elastin -0.0061417
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 -0.0061395
PLK1 polo-like kinase 1 -0.006135
GPA33 glycoprotein A33 (transmembrane) -0.00611228
ZNF160 zinc finger protein 160 -0.00610945
SUN1 Sad1 and UNC84 domain containing 1 -0.00610445
ELAC2 elaC ribonuclease Z 2 -0.00609486
SEPTIN10 septin 10 -0.00608233
RAD21 RAD21 homolog (S. pombe) -0.00604387
ADGRG6 adhesion G protein-coupled receptor G6 -0.00603882
CEL carboxyl ester lipase -0.00603192
IPO9 importin 9 -0.00602166
ZBED5 zinc finger, BED-type containing 5 -0.00601574
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -0.00601137
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) -0.00601099
NEMP1 nuclear envelope integral membrane protein 1 -0.0059903
DNASE1L3 deoxyribonuclease I-like 3 -0.00598916
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00598018
DYNLL1 dynein, light chain, LC8-type 1 -0.00595938
EXOSC10 exosome component 10 -0.00594703
TRIB2 tribbles pseudokinase 2 -0.00593904
CBX1 chromobox homolog 1 -0.00591723
MMD monocyte to macrophage differentiation-associated -0.0059162
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00591013
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -0.00589943
RCN2 reticulocalbin 2, EF-hand calcium binding domain -0.00589832
EIF5A eukaryotic translation initiation factor 5A -0.00589651
ACAA2 acetyl-CoA acyltransferase 2 -0.00589594
FLT1 fms-related tyrosine kinase 1 -0.00589288
KLF13 Kruppel-like factor 13 -0.00588476
TNC tenascin C -0.0058783
FBLN2 fibulin 2 -0.00585682
HNRNPR heterogeneous nuclear ribonucleoprotein R -0.00584582
FAM3C family with sequence similarity 3, member C -0.00584554
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -0.00584045
THOC6 THO complex 6 -0.00583754
LUM lumican -0.0058216
PCLAF PCNA clamp associated factor -0.0058206
PDGFD platelet derived growth factor D -0.00581426
PNN pinin, desmosome associated protein -0.00581206
FBXO2 F-box protein 2 -0.00581061
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00579973
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.0057831
AKT1 v-akt murine thymoma viral oncogene homolog 1 -0.00578074
CHIC2 cysteine-rich hydrophobic domain 2 -0.00576228
PDGFRL platelet-derived growth factor receptor-like -0.00575161
STEAP3 STEAP family member 3, metalloreductase -0.00574486
FBLN1 fibulin 1 -0.00572363
TK1 thymidine kinase 1, soluble -0.00571597
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -0.00570666
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.0056971
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00568905
TACC3 transforming, acidic coiled-coil containing protein 3 -0.00568035
DUT deoxyuridine triphosphatase -0.00567325
UNC5B unc-5 homolog B (C. elegans) -0.00566583
ABHD3 abhydrolase domain containing 3 -0.00566492
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -0.00565677
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00564292
MYH11 myosin, heavy chain 11, smooth muscle -0.00563194
OSBPL10 oxysterol binding protein-like 10 -0.00562277
EML4 echinoderm microtubule associated protein like 4 -0.00562125
PLEC plectin -0.00562113
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -0.00561302
PRRX1 paired related homeobox 1 -0.00560146
TOB1 transducer of ERBB2, 1 -0.00559794
NUTF2 nuclear transport factor 2 -0.00558866
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.00558613
DVL1 dishevelled segment polarity protein 1 -0.00558178
ERBB3 erb-b2 receptor tyrosine kinase 3 -0.0055747
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00555262
CBX5 chromobox homolog 5 -0.00554504
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00554494
PCDH17 protocadherin 17 -0.00554428
NPY1R neuropeptide Y receptor Y1 -0.00554321
PAQR4 progestin and adipoQ receptor family member IV -0.00554295