| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | Bloom syndrome, RecQ helicase-like|The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 641) |
| External Link | https://ncbi.nlm.nih.gov/gene/641 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the BLM gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0240004 |
| XPO7 | exportin 7 | 0.0157877 |
| BST2 | bone marrow stromal cell antigen 2 | 0.0128166 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.0127246 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0122549 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0119128 |
| MGLL | monoglyceride lipase | 0.0118663 |
| RGS5 | regulator of G-protein signaling 5 | 0.0118629 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 0.0117907 |
| MATN2 | matrilin 2 | 0.0117714 |
| TXLNA | taxilin alpha | 0.0109081 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0102781 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 0.0099591 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00995023 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.00982332 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00981824 |
| TMEM255A | transmembrane protein 255A | 0.00971611 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00966827 |
| PLK1 | polo-like kinase 1 | 0.00966774 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00964615 |
| NVL | nuclear VCP-like | 0.00957342 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.00955048 |
| BEX1 | brain expressed, X-linked 1 | 0.00943756 |
| CA2 | carbonic anhydrase II | 0.00939207 |
| RET | ret proto-oncogene | 0.00923491 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00920145 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00919072 |
| TNS1 | tensin 1 | 0.00916859 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00909106 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00884172 |
| ADCY9 | adenylate cyclase 9 | 0.00883005 |
| INSR | insulin receptor | 0.00874875 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00869833 |
| ZNF160 | zinc finger protein 160 | 0.00866757 |
| PWWP3A | PWWP domain containing 3A, DNA repair factor | 0.00851095 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00849836 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 0.00842053 |
| IPO13 | importin 13 | 0.00840617 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00840395 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.0082963 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00828725 |
| TCTA | T-cell leukemia translocation altered | 0.00814625 |
| ITM2C | integral membrane protein 2C | 0.00813483 |
| PNN | pinin, desmosome associated protein | 0.00808284 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.00801585 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00798752 |
| SDC1 | syndecan 1 | 0.00793954 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.00787053 |
| CLEC11A | C-type lectin domain family 11, member A | 0.0078546 |
| MX1 | MX dynamin-like GTPase 1 | 0.00782669 |
| IVD | isovaleryl-CoA dehydrogenase | 0.00776414 |
| FBXW12 | F-box and WD repeat domain containing 12 | 0.00773559 |
| CYTH1 | cytohesin 1 | 0.00762584 |
| TNS3 | tensin 3 | 0.00762065 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00760766 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | 0.00760308 |
| WDR6 | WD repeat domain 6 | 0.0075729 |
| ZNF721 | zinc finger protein 721 | 0.00757278 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00750359 |
| GOLGA8H | golgin A8 family, member H | 0.00750099 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.00748981 |
| TUBB2B | tubulin, beta 2B class IIb | 0.0074319 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00738345 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0073823 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00733212 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00726879 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00720184 |
| MOK | MOK protein kinase | 0.00719243 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00715943 |
| PRDX2 | peroxiredoxin 2 | 0.00712067 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 0.00710643 |
| HOMER2 | homer scaffolding protein 2 | 0.00707188 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00706356 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00704412 |
| CD93 | CD93 molecule | 0.00704154 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.00691282 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | 0.00683517 |
| AMOTL2 | angiomotin like 2 | 0.00682345 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00680559 |
| OPHN1 | oligophrenin 1 | 0.00679149 |
| ADCY1 | adenylate cyclase 1 (brain) | 0.0067814 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.00676001 |
| TAOK3 | TAO kinase 3 | 0.0067149 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00671418 |
| CALCA | calcitonin-related polypeptide alpha | 0.00670443 |
| CDV3 | CDV3 homolog (mouse) | 0.00670007 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.00668484 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.00667992 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00665515 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.00661476 |
| MMP1 | matrix metallopeptidase 1 | 0.0066085 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.00659778 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | 0.00658349 |
| TMEM63A | transmembrane protein 63A | 0.00655903 |
| NAV2 | neuron navigator 2 | 0.0065443 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00654308 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | 0.00652657 |
| RRBP1 | ribosome binding protein 1 | 0.00646939 |
| ATP5F1D | ATP synthase F1 subunit delta | 0.00643555 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00643502 |
| SNX1 | sorting nexin 1 | 0.00643234 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | 0.0064292 |
| AFF1 | AF4/FMR2 family, member 1 | 0.00642266 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00641156 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.00641153 |
| LONP2 | lon peptidase 2, peroxisomal | 0.00638804 |
| PXDN | peroxidasin | 0.00633188 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | 0.00632934 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00632146 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00629983 |
| RUFY2 | RUN and FYVE domain containing 2 | 0.006296 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.00628985 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.00625408 |
| RBM47 | RNA binding motif protein 47 | 0.00622728 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.0061515 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.00614635 |
| ESYT1 | extended synaptotagmin-like protein 1 | 0.00612967 |
| RGS1 | regulator of G-protein signaling 1 | 0.00612932 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | 0.00612906 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0061226 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0061114 |
| EZR | ezrin | 0.00610198 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.00609807 |
| CDC20 | cell division cycle 20 | 0.00609272 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.00606574 |
| SERINC5 | serine incorporator 5 | 0.00604235 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00603405 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.00603243 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00602349 |
| LTK | leukocyte receptor tyrosine kinase | 0.00602238 |
| MLXIP | MLX interacting protein | 0.00602113 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.00600495 |
| SETBP1 | SET binding protein 1 | 0.00599294 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00598706 |
| FAM50A | family with sequence similarity 50, member A | 0.00598643 |
| VEGFA | vascular endothelial growth factor A | 0.00596682 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) | 0.00596336 |
| POGLUT1 | protein O-glucosyltransferase 1 | 0.0059486 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.00592724 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | 0.00592638 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.0059158 |
| AGRN | agrin | 0.00590091 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.00586581 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.00584043 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 | 0.00582464 |
| GFRA1 | GDNF family receptor alpha 1 | 0.00580864 |
| XIC | X chromosome inactivation center | 0.00580177 |
| RETREG1 | reticulophagy regulator 1 | 0.00578295 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00576154 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0057565 |
| NKTR | natural killer cell triggering receptor | 0.00575345 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.00575033 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0057458 |
| SLC22A18 | solute carrier family 22, member 18 | 0.00574006 |
| SLC43A3 | solute carrier family 43, member 3 | 0.0057214 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | 0.00571139 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00570383 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00568508 |
| PLCL1 | phospholipase C-like 1 | 0.00567898 |
| NID2 | nidogen 2 (osteonidogen) | 0.00567134 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa | 0.00566604 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00566453 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.00565749 |
| SPAG5 | sperm associated antigen 5 | 0.0056527 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 0.00561594 |
| AEBP1 | AE binding protein 1 | 0.00561363 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0055996 |
| MX2 | MX dynamin-like GTPase 2 | 0.00559493 |
| ACVR1B | activin A receptor, type IB | 0.00557733 |
| ADAMTSL3 | ADAMTS-like 3 | 0.00556747 |
| PHIP | pleckstrin homology domain interacting protein | 0.00556018 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.00555453 |
| KPNB1 | karyopherin (importin) beta 1 | 0.00555292 |
| TRIM14 | tripartite motif containing 14 | 0.00554061 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.00552238 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 0.00552096 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | 0.00551639 |
| CEP43 | centrosomal protein 43 | 0.00550289 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00549555 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.00548773 |
| VIM | vimentin | 0.00548665 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00548201 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.00547639 |
| THBD | thrombomodulin | 0.00546841 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.00545304 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.00545299 |
| ZNF611 | zinc finger protein 611 | 0.00544803 |
| PRR11 | proline rich 11 | 0.00543949 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00543764 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00542542 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.00542015 |
| SRM | spermidine synthase | 0.00541812 |
| TYROBP | TYRO protein tyrosine kinase binding protein | 0.00541382 |
| HDLBP | high density lipoprotein binding protein | 0.00541159 |
| EMP2 | epithelial membrane protein 2 | 0.00541026 |
| TRPV2 | transient receptor potential cation channel, subfamily V, member 2 | 0.00540683 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 | 0.0054029 |
| RBM5 | RNA binding motif protein 5 | 0.00540133 |
| LONP1 | lon peptidase 1, mitochondrial | 0.00540098 |
| COL11A1 | collagen, type XI, alpha 1 | 0.00539936 |
| DHFR | dihydrofolate reductase | 0.00538389 |
| CPNE1 | copine I | 0.00538207 |
| IRS1 | insulin receptor substrate 1 | 0.00537343 |
| CES3 | carboxylesterase 3 | 0.00537338 |
| MSLN | mesothelin | 0.00537312 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.00537277 |
| EXOSC10 | exosome component 10 | 0.00537047 |
| NPIPA1 | nuclear pore complex interacting protein family, member A1 | 0.00537008 |
| DIAPH2 | diaphanous-related formin 2 | 0.0053635 |
| ZNF395 | zinc finger protein 395 | 0.00536114 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | 0.00536038 |
| SASH1 | SAM and SH3 domain containing 1 | 0.00535406 |
| ZNF593 | zinc finger protein 593 | 0.00534896 |
| NUP93 | nucleoporin 93kDa | 0.0053406 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | 0.00533906 |
| XPO6 | exportin 6 | 0.00533589 |
| PCYOX1 | prenylcysteine oxidase 1 | 0.00532598 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.00532235 |
| RREB1 | ras responsive element binding protein 1 | 0.00531919 |
| C9ORF3 | chromosome 9 open reading frame 3 | 0.00530956 |
| EDF1 | endothelial differentiation-related factor 1 | 0.00529051 |
| LIN28A | lin-28 homolog A (C. elegans) | 0.00527225 |
| IGSF3 | immunoglobulin superfamily, member 3 | 0.00526821 |
| MFSD1 | major facilitator superfamily domain containing 1 | 0.00526595 |
| USP22 | ubiquitin specific peptidase 22 | 0.00526336 |
| GAB2 | GRB2-associated binding protein 2 | 0.00526311 |
| KRT8 | keratin 8, type II | 0.00524973 |
| FOXJ3 | forkhead box J3 | 0.00524893 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00524641 |
| SARAF | store-operated calcium entry-associated regulatory factor | 0.0052432 |
| NEK9 | NIMA-related kinase 9 | 0.0052387 |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 | 0.00522817 |
| CLC | Charcot-Leyden crystal galectin | 0.00522765 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa | 0.00521713 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | 0.00521153 |
| SORBS3 | sorbin and SH3 domain containing 3 | 0.00520664 |
| AREG | amphiregulin | 0.00517489 |
| NUCLEOLIN | nucleolin multifunctional protein | 0.0051723 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00516202 |
| NUDC | nudC nuclear distribution protein | 0.00515865 |
| COASY | CoA synthase | 0.00515551 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.00515261 |
| ESR1 | estrogen receptor 1 | 0.00515113 |
| LDB2 | LIM domain binding 2 | 0.00513948 |
| CCNA2 | cyclin A2 | 0.00512779 |
| EXPH5 | exophilin 5 | 0.00511068 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | 0.00510679 |
| GRHPR | glyoxylate reductase/hydroxypyruvate reductase | 0.0050912 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00508909 |
| BARD1 | BRCA1 associated RING domain 1 | 0.00507894 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0152229 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.0143148 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0138618 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.01315 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.0130781 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.0129103 |
| MMP7 | matrix metallopeptidase 7 | -0.012619 |
| LTF | lactotransferrin | -0.0123269 |
| S100A2 | S100 calcium binding protein A2 | -0.0121346 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0120132 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.011868 |
| KRT5 | keratin 5, type II | -0.0117949 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0116596 |
| CLEC2B | C-type lectin domain family 2, member B | -0.0109866 |
| NDP | Norrie disease (pseudoglioma) | -0.0108575 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.0107888 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.0107347 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.0103237 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0100537 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.00996359 |
| S100A9 | S100 calcium binding protein A9 | -0.00988642 |
| TPD52L1 | tumor protein D52-like 1 | -0.00985557 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00977671 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00971382 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00964466 |
| PTK2 | protein tyrosine kinase 2 | -0.00958521 |
| CD69 | CD69 molecule | -0.00956494 |
| CSTA | cystatin A (stefin A) | -0.00941586 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.0094018 |
| DCK | deoxycytidine kinase | -0.00932728 |
| COG5 | component of oligomeric golgi complex 5 | -0.00927259 |
| KRT6A | keratin 6A, type II | -0.00926956 |
| S100P | S100 calcium binding protein P | -0.00901523 |
| KRT17 | keratin 17, type I | -0.00896755 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.00872964 |
| JUNB | jun B proto-oncogene | -0.00868668 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00866965 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00862338 |
| IQCG | IQ motif containing G | -0.00859534 |
| TMEM14A | transmembrane protein 14A | -0.00844017 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00836378 |
| PDHX | pyruvate dehydrogenase complex, component X | -0.008315 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00825224 |
| PITX3 | paired-like homeodomain 3 | -0.0082081 |
| WTAP | Wilms tumor 1 associated protein | -0.00820513 |
| ANXA1 | annexin A1 | -0.00819251 |
| WBP5 | WW domain binding protein 5 | -0.00817624 |
| AGR2 | anterior gradient 2 | -0.00815036 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00814421 |
| PLTP | phospholipid transfer protein | -0.00811995 |
| GOLT1B | golgi transport 1B | -0.00811767 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | -0.00811267 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00810776 |
| FST | follistatin | -0.00810001 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 | -0.00807496 |
| GPM6A | glycoprotein M6A | -0.00804607 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.0080178 |
| KRT15 | keratin 15, type I | -0.00800435 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | -0.00791284 |
| NPR3 | natriuretic peptide receptor 3 | -0.00789468 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00779206 |
| PCP4 | Purkinje cell protein 4 | -0.00774243 |
| ITK | IL2-inducible T-cell kinase | -0.00771456 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 | -0.00767308 |
| GPR88 | G protein-coupled receptor 88 | -0.00764027 |
| CADM1 | cell adhesion molecule 1 | -0.00756691 |
| FHL1 | four and a half LIM domains 1 | -0.00754471 |
| NMT2 | N-myristoyltransferase 2 | -0.00751947 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00747128 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00746764 |
| STK38L | serine/threonine kinase 38 like | -0.00745024 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00744123 |
| PLBD1 | phospholipase B domain containing 1 | -0.00743979 |
| SOSTDC1 | sclerostin domain containing 1 | -0.00741696 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00741331 |
| PERP | PERP, TP53 apoptosis effector | -0.00741064 |
| KRT14 | keratin 14, type I | -0.00738931 |
| BCL2A1 | BCL2-related protein A1 | -0.00738084 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | -0.0073487 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.00733825 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00733527 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00731165 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00728049 |
| CP | ceruloplasmin (ferroxidase) | -0.00722164 |
| CNTN1 | contactin 1 | -0.00721083 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00720727 |
| SAR1B | secretion associated, Ras related GTPase 1B | -0.00720347 |
| AQP4 | aquaporin 4 | -0.00720091 |
| HIST1H2AE | histone cluster 1, H2ae | -0.00717421 |
| GOLGA7 | golgin A7 | -0.00713925 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00711999 |
| PKP1 | plakophilin 1 | -0.00709388 |
| HPGDS | hematopoietic prostaglandin D synthase | -0.00708259 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0070702 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00703611 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00703118 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | -0.00701894 |
| PDCD10 | programmed cell death 10 | -0.00701545 |
| MAL | mal, T-cell differentiation protein | -0.00701418 |
| MYBPC1 | myosin binding protein C, slow type | -0.00700861 |
| ZNF277 | zinc finger protein 277 | -0.00698092 |
| CPD | carboxypeptidase D | -0.00697615 |
| IL1RN | interleukin 1 receptor antagonist | -0.00696355 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00695094 |
| MB | myoglobin | -0.00693826 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00693164 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein | -0.00691639 |
| LIMK2 | LIM domain kinase 2 | -0.00690709 |
| TSPAN6 | tetraspanin 6 | -0.00690061 |
| EMX2 | empty spiracles homeobox 2 | -0.00689455 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00688316 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00686011 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.0068548 |
| GCA | grancalcin, EF-hand calcium binding protein | -0.00685426 |
| IRF6 | interferon regulatory factor 6 | -0.0068417 |
| TMEM47 | transmembrane protein 47 | -0.00683592 |
| DNAJA2 | DnaJ (Hsp40) homolog, subfamily A, member 2 | -0.00683487 |
| CALB1 | calbindin 1, 28kDa | -0.00679104 |
| TTC33 | tetratricopeptide repeat domain 33 | -0.00678434 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00677456 |
| ING2 | inhibitor of growth family, member 2 | -0.00676638 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00676588 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00675821 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00669244 |
| FOXC1 | forkhead box C1 | -0.00669184 |
| CST3 | cystatin C | -0.00669092 |
| MLF1 | myeloid leukemia factor 1 | -0.00668562 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | -0.00667853 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | -0.00666527 |
| NME5 | NME/NM23 family member 5 | -0.00666314 |
| MAGEA3 | melanoma antigen family A3 | -0.00663528 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00663158 |
| MLF2 | myeloid leukemia factor 2 | -0.0066207 |
| FBXO3 | F-box protein 3 | -0.00661576 |
| FOXG1 | forkhead box G1 | -0.00660729 |
| TGFB1 | transforming growth factor, beta 1 | -0.00657672 |
| PDLIM4 | PDZ and LIM domain 4 | -0.00655722 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) | -0.00655622 |
| C5ORF28 | chromosome 5 open reading frame 28 | -0.00655182 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00655096 |
| STX8 | syntaxin 8 | -0.00649988 |
| ASF1A | anti-silencing function 1A histone chaperone | -0.0064879 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.00648203 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00647921 |
| TMEM165 | transmembrane protein 165 | -0.00646427 |
| COMMD10 | COMM domain containing 10 | -0.00645494 |
| EHF | ets homologous factor | -0.00645259 |
| CLU | clusterin | -0.00645106 |
| GFAP | glial fibrillary acidic protein | -0.00641311 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.00641299 |
| SSX1 | synovial sarcoma, X breakpoint 1 | -0.00638035 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00636282 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | -0.00635399 |
| TUBA1A | tubulin, alpha 1a | -0.00635362 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00635346 |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 | -0.00634756 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -0.00634132 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00631725 |
| DUSP2 | dual specificity phosphatase 2 | -0.00631049 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.0063071 |
| CCNG2 | cyclin G2 | -0.00630548 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00629269 |
| IL33R | interleukin 33 receptor | -0.00628656 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00627659 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00627638 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.00626727 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.00625607 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.00625498 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 | -0.00623687 |
| CRYAB | crystallin, alpha B | -0.00622839 |
| AK4 | adenylate kinase 4 | -0.00622199 |
| SKP1 | S-phase kinase-associated protein 1 | -0.00621876 |
| S100A8 | S100 calcium binding protein A8 | -0.00621706 |
| PFN2 | profilin 2 | -0.00618222 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00617556 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00615742 |
| GABRA1 | gamma-aminobutyric acid (GABA) A receptor, alpha 1 | -0.00615241 |
| COPS7A | COP9 signalosome subunit 7A | -0.00613467 |
| ANO3 | anoctamin 3 | -0.00613103 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | -0.00612744 |
| NIPSNAP2 | nipsnap homolog 2 | -0.00612422 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00610772 |
| STRAP | serine/threonine kinase receptor associated protein | -0.00608162 |
| LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 | -0.00608132 |
| NMU | neuromedin U | -0.00605633 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.00604818 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma | -0.00602838 |
| NSL1 | NSL1, MIS12 kinetochore complex component | -0.00602434 |
| HDAC9 | histone deacetylase 9 | -0.00599839 |
| BAG2 | BCL2-associated athanogene 2 | -0.00599817 |
| SRPK2 | SRSF protein kinase 2 | -0.00598754 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00598587 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00595942 |
| FAM198B | family with sequence similarity 198, member B | -0.00595937 |
| SUMO1 | small ubiquitin-like modifier 1 | -0.00595896 |
| COMT | catechol-O-methyltransferase | -0.00594386 |
| GTF2B | general transcription factor IIB | -0.00593276 |
| LY96 | lymphocyte antigen 96 | -0.00590793 |
| LOXL1 | lysyl oxidase-like 1 | -0.00589936 |
| MMP10 | matrix metallopeptidase 10 | -0.00589547 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.00588974 |
| TMEM106B | transmembrane protein 106B | -0.00585689 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00585686 |
| SELENOF | selenoprotein F | -0.0058487 |
| ADCY2 | adenylate cyclase 2 (brain) | -0.00582045 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0058196 |
| DIO2 | deiodinase, iodothyronine, type II | -0.00581475 |
| MED21 | mediator complex subunit 21 | -0.00581357 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A | -0.00580578 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | -0.00579995 |
| CCN3 | cellular communication network factor 3 | -0.00579738 |
| PHYH | phytanoyl-CoA 2-hydroxylase | -0.00578728 |
| KRT19 | keratin 19, type I | -0.00578632 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.00577838 |
| ATG5 | autophagy related 5 | -0.00577275 |
| RIT1 | Ras-like without CAAX 1 | -0.00577215 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00576343 |
| ARPP21 | cAMP-regulated phosphoprotein, 21kDa | -0.00575912 |
| TXNIP | thioredoxin interacting protein | -0.00575876 |
| SLC25A46 | solute carrier family 25, member 46 | -0.00574559 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0057439 |
| ORC5 | origin recognition complex, subunit 5 | -0.00573818 |
| HDAC2 | histone deacetylase 2 | -0.00573517 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein | -0.00572914 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | -0.00571752 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00571381 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00571351 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.0057135 |
| TUBA4A | tubulin, alpha 4a | -0.00571255 |
| GLUL | glutamate-ammonia ligase | -0.00570963 |
| ETNK1 | ethanolamine kinase 1 | -0.00570687 |
| CHI3L2 | chitinase 3-like 2 | -0.00570516 |
| SH3GL2 | SH3-domain GRB2-like 2 | -0.00570063 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00569485 |
| LCN2 | lipocalin 2 | -0.0056876 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.00568724 |
| NPTN | neuroplastin | -0.00568327 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.0056792 |
| IL1R2 | interleukin 1 receptor, type II | -0.00567061 |
| NREP | neuronal regeneration related protein | -0.00565666 |
| CRTAM | cytotoxic and regulatory T cell molecule | -0.00565245 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00564695 |
| PAX6 | paired box 6 | -0.0056455 |
| DRG1 | developmentally regulated GTP binding protein 1 | -0.0056436 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00563346 |
| LARP6 | La ribonucleoprotein domain family, member 6 | -0.00563343 |
| SLN | sarcolipin | -0.0056333 |
| MBD2 | methyl-CpG binding domain protein 2 | -0.00562545 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | -0.00561626 |
