BMP2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description bone morphogenetic protein 2|The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 650)
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Genes

290 genes differentially expressed following the BMP2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
FPR1 formyl peptide receptor 1 2.44319
IL22RA1 interleukin 22 receptor, alpha 1 2.44319
SPINK4 serine peptidase inhibitor, Kazal type 4 2.44319
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 2.44319
NXPH4 neurexophilin 4 2.44319
PCDHB7 protocadherin beta 7 2.44319
TMEM151A transmembrane protein 151A 2.44319
DPEP2 dipeptidase 2 2.44319
PCDHGB3 protocadherin gamma subfamily B, 3 2.44319
CCL5 chemokine (C-C motif) ligand 5 2.44319
AKAP14 A kinase (PRKA) anchor protein 14 2.44319
UCN urocortin 2.44319
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 2.44319
FER1L6 fer-1-like family member 6 2.44319
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 2.44319
GPR75 G protein-coupled receptor 75 2.44319
HLF hepatic leukemia factor 2.44319
RHOXF2B Rhox homeobox family, member 2B 2.44319
BBC3 BCL2 binding component 3 2.44319
NAPSA napsin A aspartic peptidase 2.44319
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 2.44319
LRRC56 leucine rich repeat containing 56 2.44319
PAX3 paired box 3 2.44319
FAM229A family with sequence similarity 229, member A 2.44319
YY2 YY2 transcription factor 2.44319
LGI1 leucine-rich, glioma inactivated 1 2.44319
PTK6 protein tyrosine kinase 6 2.44319
AVP arginine vasopressin 2.44319
CPLX3 complexin 3 2.44319
KLLN killin, p53-regulated DNA replication inhibitor 2.44319
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.44319
GABARAP GABA(A) receptor-associated protein 2.44319
C1ORF146 chromosome 1 open reading frame 146 2.44319
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 2.44319
SLC15A5 solute carrier family 15, member 5 2.44319
ASB17 ankyrin repeat and SOCS box containing 17 2.44319
STAG3 stromal antigen 3 2.44319
MFAP5 microfibrillar associated protein 5 2.44319
CCDC85A coiled-coil domain containing 85A 2.44319
UNC45B unc-45 homolog B (C. elegans) 2.44319
RFPL3 ret finger protein-like 3 2.44319
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 2.44319
BSX brain-specific homeobox 2.44319
RNASE6 ribonuclease, RNase A family, k6 2.44319
TMEM59L transmembrane protein 59-like 2.44319
LOC124900192 uncharacterized LOC124900192 2.44319
CABCOCO1 ciliary associated calcium binding coiled-coil 1 2.44319
CBLIF cobalamin binding intrinsic factor 2.44319
CCN5 cellular communication network factor 5 2.44319
SPATS1 spermatogenesis associated, serine-rich 1 2.44319
CES4A carboxylesterase 4A 2.44319
GBP6 guanylate binding protein family, member 6 2.44319
CLDN16 claudin 16 2.44319
CAPN9 calpain 9 2.44319
CD300LF CD300 molecule-like family member f 2.44319
RNF227 ring finger protein 227 2.44319
CFAP276 cilia and flagella associated protein 276 2.44319
CSNK2A2IP casein kinase 2 subunit alpha' interacting protein 2.44319
SPMAP2L sperm microtubule associated protein 2 like 2.44319
DRC11 dynein regulatory complex subunit 11 2.44319
DRC5 dynein regulatory complex subunit 5 2.44319
LOC124903372 uncharacterized LOC124903372 2.44319
SPAAR small regulatory polypeptide of amino acid response 2.44319
SMIM31 small integral membrane protein 31 2.44319
PEAK3 PEAK family member 3 2.44319
ACP4 acid phosphatase 4 2.44319
UNC5CL unc-5 homolog C (C. elegans)-like 2.44319
FMO2 flavin containing monooxygenase 2 (non-functional) 2.44319
NR1I3 nuclear receptor subfamily 1, group I, member 3 2.44319
CD48 CD48 molecule 2.44319
IRF8 interferon regulatory factor 8 2.44319
CCDC18 coiled-coil domain containing 18 2.44319
TMIE transmembrane inner ear 2.44319
PTPRH protein tyrosine phosphatase, receptor type, H 2.44319
PCDHA3 protocadherin alpha 3 2.44319
RNASE4 ribonuclease, RNase A family, 4 2.44319
LCMT1 leucine carboxyl methyltransferase 1 2.44319
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 2.44319
SCRT1 scratch family zinc finger 1 2.44319
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 2.44319
PROZ protein Z, vitamin K-dependent plasma glycoprotein 2.44319
OR1C1 olfactory receptor, family 1, subfamily C, member 1 2.44319
DOK7 docking protein 7 2.44319
TIMD4 T-cell immunoglobulin and mucin domain containing 4 2.44319
ZNF862 zinc finger protein 862 2.44319
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G 2.44319
TLR8 toll-like receptor 8 2.44319
S1PR4 sphingosine-1-phosphate receptor 4 2.44319
ISM2 isthmin 2 2.44319
GAL3ST2 galactose-3-O-sulfotransferase 2 2.44319
F2RL2 coagulation factor II (thrombin) receptor-like 2 2.44319
MAMLD1 mastermind-like domain containing 1 2.44319
PEBP1 phosphatidylethanolamine binding protein 1 2.44319
PCDHGA3 protocadherin gamma subfamily A, 3 2.44319
LMOD2 leiomodin 2 (cardiac) 2.44319
ALOXE3 arachidonate lipoxygenase 3 2.44319
VWA3A von Willebrand factor A domain containing 3A 2.44319
EFHD1 EF-hand domain family, member D1 2.44319
TEKT2 tektin 2 (testicular) 2.44319
TBC1D10C TBC1 domain family, member 10C 2.44319
C2ORF66 chromosome 2 open reading frame 66 2.44319
AQP4 aquaporin 4 2.44319
MAGEA2B melanoma antigen family A2B 2.44319
MR1 major histocompatibility complex, class I-related 2.44319
HAMP hepcidin antimicrobial peptide 2.44319
GP6 glycoprotein VI (platelet) 2.44319
TNN tenascin N 2.44319
HLA-G major histocompatibility complex, class I, G 2.44319
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 2.44319
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 2.44319
AQP8 aquaporin 8 2.44319
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 2.44319
ZCCHC18 zinc finger, CCHC domain containing 18 2.44319
MEIS2 Meis homeobox 2 2.44319
ADCY4 adenylate cyclase 4 2.44319
CNGB1 cyclic nucleotide gated channel beta 1 2.44319
SFTA2 surfactant associated 2 2.44319
TTC29 tetratricopeptide repeat domain 29 2.44319
MB myoglobin 2.44319
GOLGA8N golgin A8 family, member N 2.44319
EIF4E1B eukaryotic translation initiation factor 4E family member 1B 2.44319
MZB1 marginal zone B and B1 cell-specific protein 2.44319
ESPNL espin-like 2.44319
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 2.44319
INSL6 insulin-like 6 2.44319
ZNF843 zinc finger protein 843 2.44319
SIRPG signal-regulatory protein gamma 2.44319
CTXN2 cortexin 2 2.44319
ACSBG2 acyl-CoA synthetase bubblegum family member 2 2.44319
DLX3 distal-less homeobox 3 2.44319
SDS serine dehydratase 2.44319
NT5C1B 5'-nucleotidase, cytosolic IB 2.44319
CTSF cathepsin F 2.44319
TMPPE transmembrane protein with metallophosphoesterase domain 2.44319
SLC36A3 solute carrier family 36, member 3 2.44319
SLC51B solute carrier family 51, beta subunit 2.44319
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 2.44319
RP1 retinitis pigmentosa 1 (autosomal dominant) 2.44319
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 2.44319
FITM1 fat storage-inducing transmembrane protein 1 2.44319
APOL3 apolipoprotein L, 3 2.44319
GLT6D1 glycosyltransferase 6 domain containing 1 2.44319
OR11G2 olfactory receptor, family 11, subfamily G, member 2 2.44319
ANGPTL6 angiopoietin-like 6 2.44319
OR10G3 olfactory receptor, family 10, subfamily G, member 3 2.44319
GCM1 glial cells missing homolog 1 (Drosophila) 2.44319
TRAF3IP3 TRAF3 interacting protein 3 2.44319
LAMP3 lysosomal-associated membrane protein 3 2.44319
TAS2R43 taste receptor, type 2, member 43 2.44319
XCR1 chemokine (C motif) receptor 1 2.44319
CETP cholesteryl ester transfer protein, plasma 2.44319
CD80 CD80 molecule 2.44319
EPX eosinophil peroxidase 2.44319
PITX3 paired-like homeodomain 3 2.44319
RDH16 retinol dehydrogenase 16 (all-trans) 2.44319
TGM1 transglutaminase 1 2.44319
KRT17 keratin 17, type I 2.44319
ZHX2 zinc fingers and homeoboxes 2 2.44319
C17ORF107 chromosome 17 open reading frame 107 2.44319
CLEC2A C-type lectin domain family 2, member A 2.44319
ECM1 extracellular matrix protein 1 2.44319
PTGDR prostaglandin D2 receptor (DP) 2.44319
ALOX5AP arachidonate 5-lipoxygenase-activating protein 2.44319
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 2.44319
MED9 mediator complex subunit 9 2.44319
CD226 CD226 molecule 2.44319
DKK2 dickkopf WNT signaling pathway inhibitor 2 2.44319
PRSS57 protease, serine, 57 2.44319
NODAL nodal growth differentiation factor 2.43289
QPRT quinolinate phosphoribosyltransferase 2.41497
WDR5B WD repeat domain 5B 2.40463
FAM209A family with sequence similarity 209, member A 2.40463
STKLD1 serine/threonine kinase-like domain containing 1 2.40463
NFAM1 NFAT activating protein with ITAM motif 1 2.394
CIDEB cell death-inducing DFFA-like effector b 2.35202
ZNF12 zinc finger protein 12 2.34464
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 2.33692
USP49 ubiquitin specific peptidase 49 2.3187
FBXW8 F-box and WD repeat domain containing 8 2.3187
UNC13C unc-13 homolog C (C. elegans) 2.31355
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.30178
OVGP1 oviductal glycoprotein 1, 120kDa 2.29225
ZNF660-ZNF197 ZNF660-ZNF197 readthrough 2.28873
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 2.27686
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 2.2729
PARD6G par-6 family cell polarity regulator gamma 2.27079
LEPROT leptin receptor overlapping transcript 2.25351
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 2.24088
N4BP2L2 NEDD4 binding protein 2-like 2 2.18843
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) 2.18491
WDR53 WD repeat domain 53 2.15989
SYNE4 spectrin repeat containing, nuclear envelope family member 4 2.15989
GAREM2 GRB2 associated regulator of MAPK1 subtype 2 2.15163
CRY1 cryptochrome circadian clock 1 2.12189
RBM42 RNA binding motif protein 42 2.11522
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 2.08705
TMEM26 transmembrane protein 26 2.07358
C8ORF76 chromosome 8 open reading frame 76 2.04804
HINFP histone H4 transcription factor 2.04015
COMMD10 COMM domain containing 10 2.0339
PALS1 protein associated with LIN7 1, MAGUK p55 family member 2.03153
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) 2.02732
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 2.00008

decreased expression

Symbol Name Standardized Value
FAM240C family with sequence similarity 240 member C -2.44319
TM4SF1 transmembrane 4 L six family member 1 -2.44319
STRIP2 striatin interacting protein 2 -2.44319
ESRRB estrogen-related receptor beta -2.44319
RGL4 ral guanine nucleotide dissociation stimulator-like 4 -2.44319
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like -2.44319
GMNN geminin, DNA replication inhibitor -2.44319
TBC1D4 TBC1 domain family, member 4 -2.44319
OSMR oncostatin M receptor -2.44319
ZNF804A zinc finger protein 804A -2.44319
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -2.44319
NKD1 naked cuticle homolog 1 (Drosophila) -2.44319
WAS Wiskott-Aldrich syndrome -2.44319
MMRN2 multimerin 2 -2.44319
KCNK15 potassium channel, two pore domain subfamily K, member 15 -2.44319
WNT3A wingless-type MMTV integration site family, member 3A -2.44319
ZEB2 zinc finger E-box binding homeobox 2 -2.44319
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -2.44319
ITPRID2 ITPR interacting domain containing 2 -2.44319
TRIM38 tripartite motif containing 38 -2.44319
RGS20 regulator of G-protein signaling 20 -2.44319
PGLYRP1 peptidoglycan recognition protein 1 -2.44319
C1ORF167 chromosome 1 open reading frame 167 -2.44319
TACSTD2 tumor-associated calcium signal transducer 2 -2.44319
PTPRM protein tyrosine phosphatase, receptor type, M -2.44319
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 -2.44319
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -2.44319
HRH3 histamine receptor H3 -2.44319
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 -2.44319
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -2.44319
LRRD1 leucine-rich repeats and death domain containing 1 -2.44319
HPCAL4 hippocalcin like 4 -2.44319
PPP1R36 protein phosphatase 1, regulatory subunit 36 -2.44319
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -2.44319
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -2.44319
XK X-linked Kx blood group -2.44319
CDR2L cerebellar degeneration-related protein 2-like -2.44319
SDCCAG8 serologically defined colon cancer antigen 8 -2.44319
OR4D1 olfactory receptor, family 4, subfamily D, member 1 -2.44319
ATP10B ATPase, class V, type 10B -2.44319
MKNK1 MAP kinase interacting serine/threonine kinase 1 -2.44319
BAIAP2L2 BAI1-associated protein 2-like 2 -2.44319
CIROZ ciliated left-right organizer protein containing ZP-N domains -2.44319
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) -2.44319
ARHGAP20 Rho GTPase activating protein 20 -2.44319
TSPAN10 tetraspanin 10 -2.44319
TBXA2R thromboxane A2 receptor -2.44319
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 -2.44319
CEP170 centrosomal protein 170kDa -2.44319
POTEI POTE ankyrin domain family, member I -2.44319
BOLL boule-like RNA-binding protein -2.44319
DAND5 DAN domain family member 5, BMP antagonist -2.44319
TRHR thyrotropin-releasing hormone receptor -2.44319
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -2.41497
PDIA3 protein disulfide isomerase family A, member 3 -2.36748
CDH23 cadherin-related 23 -2.33834
BCL9 B-cell CLL/lymphoma 9 -2.3187
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -2.31355
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -2.31239
ZNF790 zinc finger protein 790 -2.28421
NET1 neuroepithelial cell transforming 1 -2.27875
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -2.25509
SMIM24 small integral membrane protein 24 -2.24998
MEST mesoderm specific transcript -2.24847
ADORA2A adenosine A2a receptor -2.24088
DHRS13 dehydrogenase/reductase (SDR family) member 13 -2.23711
RAB24 RAB24, member RAS oncogene family -2.23323
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -2.23119
POFUT2 protein O-fucosyltransferase 2 -2.2248
SCML2 sex comb on midleg-like 2 (Drosophila) -2.19504
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -2.19504
TPST1 tyrosylprotein sulfotransferase 1 -2.17086
HMGN1 high mobility group nucleosome binding domain 1 -2.15989
FOSL2 FOS-like antigen 2 -2.15232
F13A1 coagulation factor XIII, A1 polypeptide -2.15232
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.13608
PPP1R10 protein phosphatase 1, regulatory subunit 10 -2.12854
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa -2.11522
NUDCD1 NudC domain containing 1 -2.0883
PIAS1 protein inhibitor of activated STAT, 1 -2.08757
PARP1 poly (ADP-ribose) polymerase 1 -2.03318
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) -2.03318
EPHB6 EPH receptor B6 -2.03153
NDRG2 NDRG family member 2 -2.03153
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -2.02718
ZC3H13 zinc finger CCCH-type containing 13 -2.02445
SSTR2 somatostatin receptor 2 -2.00802