BMPR2 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description bone morphogenetic protein receptor, type II (serine/threonine kinase)|This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 659)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_BMPR2
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Genes

136 co-expressed genes for BMPR2 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABI2 abl-interactor 2
ACSL3 acyl-CoA synthetase long-chain family member 3
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AKAP5 A kinase (PRKA) anchor protein 5
AKR1D1 aldo-keto reductase family 1, member D1
ANGPTL7 angiopoietin-like 7
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ART3 ADP-ribosyltransferase 3
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ASTN1 astrotactin 1
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAND1 cullin-associated and neddylation-dissociated 1
CCDC92 coiled-coil domain containing 92
CHM choroideremia (Rab escort protein 1)
CHST10 carbohydrate sulfotransferase 10
CLCN3 chloride channel, voltage-sensitive 3
CLEC16A C-type lectin domain family 16, member A
CRISP1 cysteine-rich secretory protein 1
CRISP2 cysteine-rich secretory protein 2
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSRNP2 cysteine-serine-rich nuclear protein 2
CUL3 cullin 3
CXCL6 chemokine (C-X-C motif) ligand 6
DCC DCC netrin 1 receptor
DDO D-aspartate oxidase
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DIO1 deiodinase, iodothyronine, type I
DLG5 discs, large homolog 5 (Drosophila)
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
EPHA7 EPH receptor A7
EPT1 ethanolaminephosphotransferase 1
ESM1 endothelial cell-specific molecule 1
ETV1 ets variant 1
EXOSC6 exosome component 6
FAM134B family with sequence similarity 134, member B
FAM168B family with sequence similarity 168, member B
FAM219A family with sequence similarity 219, member A
FBXO21 F-box protein 21
FBXW11 F-box and WD repeat domain containing 11
FOXO3 forkhead box O3
GBA2 glucosidase, beta (bile acid) 2
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GOLGA7 golgin A7
GPR107 G protein-coupled receptor 107
GSK3B glycogen synthase kinase 3 beta
GSTA4 glutathione S-transferase alpha 4
HDAC9 histone deacetylase 9
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
INVS inversin
IPO7 importin 7
IPO8 importin 8
IQCK IQ motif containing K
IREB2 iron-responsive element binding protein 2
KIAA0930 KIAA0930
KIDINS220 kinase D-interacting substrate, 220kDa
KIF17 kinesin family member 17
KIF1B kinesin family member 1B
KIF3B kinesin family member 3B
LOC81691 exonuclease NEF-sp
LRRTM2 leucine rich repeat transmembrane neuronal 2
MACF1 microtubule-actin crosslinking factor 1
MAGED4 melanoma antigen family D4
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MFSD8 major facilitator superfamily domain containing 8
MPPED2 metallophosphoesterase domain containing 2
MT1B metallothionein 1B
MTMR4 myotubularin related protein 4
MTRF1L mitochondrial translational release factor 1-like
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYO10 myosin X
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NCKAP1 NCK-associated protein 1
NDFIP1 Nedd4 family interacting protein 1
NFIA nuclear factor I/A
NGRN neugrin, neurite outgrowth associated
NUP133 nucleoporin 133kDa
OAZ2 ornithine decarboxylase antizyme 2
ODF2 outer dense fiber of sperm tails 2
OPHN1 oligophrenin 1
ORC4 origin recognition complex, subunit 4
PHAX phosphorylated adaptor for RNA export
PHC1 polyhomeotic homolog 1 (Drosophila)
PHF10 PHD finger protein 10
PHF2 PHD finger protein 2
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PNMAL1 paraneoplastic Ma antigen family-like 1
POGK pogo transposable element with KRAB domain
POGZ pogo transposable element with ZNF domain
PPIG peptidylprolyl isomerase G (cyclophilin G)
PPP6R2 protein phosphatase 6, regulatory subunit 2
PREPL prolyl endopeptidase-like
PRKD3 protein kinase D3
PTGDR2 prostaglandin D2 receptor 2
RABL2B RAB, member of RAS oncogene family-like 2B
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RAN RAN, member RAS oncogene family
RERE arginine-glutamic acid dipeptide (RE) repeats
RFPL3S RFPL3 antisense
RMDN3 regulator of microtubule dynamics 3
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1
RPGRIP1L RPGRIP1-like
RTN4 reticulon 4
SESN3 sestrin 3
SMYD2 SET and MYND domain containing 2
SNX27 sorting nexin family member 27
SPIRE1 spire-type actin nucleation factor 1
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STMN3 stathmin-like 3
STX12 syntaxin 12
TBC1D12 TBC1 domain family, member 12
TBC1D31 TBC1 domain family, member 31
TBCK TBC1 domain containing kinase
TMEM248 transmembrane protein 248
TMEM257 transmembrane protein 257
TMEM30A transmembrane protein 30A
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TRIM37 tripartite motif containing 37
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TSPYL4 TSPY-like 4
UBE2K ubiquitin-conjugating enzyme E2K
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4
USP33 ubiquitin specific peptidase 33
VPS26B vacuolar protein sorting 26 homolog B (S. pombe)
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
WBP2 WW domain binding protein 2
WIPF1 WAS/WASL interacting protein family, member 1
WSB2 WD repeat and SOCS box containing 2
ZFAND3 zinc finger, AN1-type domain 3
ZNF264 zinc finger protein 264
ZNF275 zinc finger protein 275
ZNF84 zinc finger protein 84