BMX Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description BMX non-receptor tyrosine kinase|This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 660)
External Link http://www.ncbi.nlm.nih.gov/gene/660
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Genes

48 interacting proteins for BMX from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ANGPT1 angiopoietin 1
ANGPT4 angiopoietin 4
APP amyloid beta (A4) precursor protein
BCAR1 breast cancer anti-estrogen resistance 1
BIN1 bridging integrator 1
BTK Bruton agammaglobulinemia tyrosine kinase
C12ORF45 chromosome 12 open reading frame 45
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CRK v-crk avian sarcoma virus CT10 oncogene homolog
EGFR epidermal growth factor receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
FADD Fas (TNFRSF6)-associated via death domain
FAF1 Fas (TNFRSF6) associated factor 1
FAS Fas cell surface death receptor
FBXO25 F-box protein 25
FGFR1 fibroblast growth factor receptor 1
FYN FYN proto-oncogene, Src family tyrosine kinase
HDAC1 histone deacetylase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA4 heat shock 70kDa protein 4
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
ITK IL2-inducible T-cell kinase
KDR kinase insert domain receptor
MET MET proto-oncogene, receptor tyrosine kinase
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PKM pyruvate kinase, muscle
PTK2 protein tyrosine kinase 2
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAP1A RAP1A, member of RAS oncogene family
RUFY1 RUN and FYVE domain containing 1
RUFY2 RUN and FYVE domain containing 2
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
TEC tec protein tyrosine kinase
TEK TEK tyrosine kinase, endothelial
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNK2 tyrosine kinase, non-receptor, 2
TP53 tumor protein p53
UBC ubiquitin C
YES1 YES proto-oncogene 1, Src family tyrosine kinase