| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | B-Raf proto-oncogene, serine/threonine kinase|This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 673) |
| External Link | https://ncbi.nlm.nih.gov/gene/673 |
| Similar Terms | |
| Downloads & Tools |
491 genes differentially expressed following the BRAF gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0352921 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.0234675 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0233522 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0214635 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.0209106 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.020881 |
| NVL | nuclear VCP-like | 0.0196096 |
| CANT1 | calcium activated nucleotidase 1 | 0.0192893 |
| FBLN1 | fibulin 1 | 0.0192612 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0191449 |
| LRRC15 | leucine rich repeat containing 15 | 0.0179436 |
| PENK | proenkephalin | 0.0178968 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.0171139 |
| GAS1 | growth arrest-specific 1 | 0.0169112 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0168502 |
| PLXNC1 | plexin C1 | 0.0166442 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.0165085 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.0160236 |
| TWIST1 | twist family bHLH transcription factor 1 | 0.0156439 |
| MAP7 | microtubule-associated protein 7 | 0.0153897 |
| RGS3 | regulator of G-protein signaling 3 | 0.0151675 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 | 0.01512 |
| DCN | decorin | 0.0148942 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.0147174 |
| CLGN | calmegin | 0.0145077 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.0143212 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 0.0142937 |
| LUM | lumican | 0.0140499 |
| STK10 | serine/threonine kinase 10 | 0.0140342 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0138258 |
| MX1 | MX dynamin-like GTPase 1 | 0.0137846 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.013775 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0137355 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0135715 |
| REEP1 | receptor accessory protein 1 | 0.0135314 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.013357 |
| AUTS2 | autism susceptibility candidate 2 | 0.0133033 |
| NUTF2 | nuclear transport factor 2 | 0.0132926 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0132763 |
| DSP | desmoplakin | 0.0132386 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.0131446 |
| MMP2 | matrix metallopeptidase 2 | 0.0130497 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.0130389 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.0129704 |
| S100A7 | S100 calcium binding protein A7 | 0.0129682 |
| CTSK | cathepsin K | 0.0129506 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | 0.0128733 |
| MFAP4 | microfibrillar-associated protein 4 | 0.0128314 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0127996 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.0127826 |
| G0S2 | G0/G1 switch 2 | 0.0127453 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.0126997 |
| ELN | elastin | 0.0126433 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0126344 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0126322 |
| ANGPTL2 | angiopoietin-like 2 | 0.0125917 |
| COL5A2 | collagen, type V, alpha 2 | 0.0124349 |
| EHD3 | EH-domain containing 3 | 0.0123832 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0122748 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.0121468 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0121059 |
| MAPK13 | mitogen-activated protein kinase 13 | 0.0121021 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0120733 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0120366 |
| KRT19 | keratin 19, type I | 0.0120192 |
| FAM13A | family with sequence similarity 13, member A | 0.0119581 |
| NOTCH1 | notch 1 | 0.0118391 |
| GPX4 | glutathione peroxidase 4 | 0.0118033 |
| GMPR | guanosine monophosphate reductase | 0.0117876 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0117321 |
| SH3BP4 | SH3-domain binding protein 4 | 0.0117191 |
| MFAP2 | microfibrillar-associated protein 2 | 0.0117049 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0115146 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.0115124 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.0113745 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0113573 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.0113358 |
| TBX3 | T-box 3 | 0.0113223 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase | 0.011278 |
| ISCU | iron-sulfur cluster assembly enzyme | 0.0112106 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0111616 |
| BGN | biglycan | 0.0110688 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0110622 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.0109733 |
| TMEM110 | transmembrane protein 110 | 0.0109373 |
| LRRC17 | leucine rich repeat containing 17 | 0.0109227 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.0109121 |
| KLF10 | Kruppel-like factor 10 | 0.0108709 |
| TSPAN13 | tetraspanin 13 | 0.0108696 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0108587 |
| PLXND1 | plexin D1 | 0.0108117 |
| ZNF544 | zinc finger protein 544 | 0.0108024 |
| PRPF4 | pre-mRNA processing factor 4 | 0.0107981 |
| KIFAP3 | kinesin-associated protein 3 | 0.0107973 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.010785 |
| LYZ | lysozyme | 0.0107546 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.0107533 |
| IFI44L | interferon-induced protein 44-like | 0.0107431 |
| SERTAD2 | SERTA domain containing 2 | 0.0107135 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0106602 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein | 0.0106375 |
| CCL15 | chemokine (C-C motif) ligand 15 | 0.0106374 |
| PLEK | pleckstrin | 0.0105786 |
| RNF144A | ring finger protein 144A | 0.0105728 |
| RCAN1 | regulator of calcineurin 1 | 0.0105677 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0105634 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0105593 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0105507 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.0104968 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0104785 |
| DLX2 | distal-less homeobox 2 | 0.0104241 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0104107 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.0103734 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.0103138 |
| MT1M | metallothionein 1M | 0.0102992 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.0101874 |
| TPSAB1 | tryptase alpha/beta 1 | 0.0101831 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.0101232 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0101173 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.0101088 |
| MX2 | MX dynamin-like GTPase 2 | 0.010106 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.0100824 |
| KLF11 | Kruppel-like factor 11 | 0.0100657 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | 0.010044 |
| SUCO | SUN domain containing ossification factor | 0.0100187 |
| RBM34 | RNA binding motif protein 34 | 0.0099336 |
| AK1 | adenylate kinase 1 | 0.00990423 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00990152 |
| COLEC12 | collectin sub-family member 12 | 0.00989927 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.00988383 |
| NEFH | neurofilament, heavy polypeptide | 0.00987204 |
| LOC283683 | uncharacterized LOC283683 | 0.00982849 |
| TRIM8 | tripartite motif containing 8 | 0.00979715 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.00979621 |
| FN1 | fibronectin 1 | 0.00978535 |
| FBXO28 | F-box protein 28 | 0.00976629 |
| RCL1 | RNA terminal phosphate cyclase-like 1 | 0.00976548 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00976236 |
| NKX3-1 | NK3 homeobox 1 | 0.00974876 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.00971175 |
| NDN | necdin, melanoma antigen (MAGE) family member | 0.00968517 |
| ACKR3 | atypical chemokine receptor 3 | 0.00967472 |
| ACP3 | acid phosphatase 3 | 0.00965385 |
| MNT | MAX network transcriptional repressor | 0.00957524 |
| CSNK1G2 | casein kinase 1, gamma 2 | 0.00957459 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00957406 |
| SC5D | sterol-C5-desaturase | 0.00954633 |
| MXRA5 | matrix-remodelling associated 5 | 0.00951476 |
| COL6A3 | collagen, type VI, alpha 3 | 0.00947095 |
| LAMB1 | laminin, beta 1 | 0.00945342 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00941851 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00941051 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.00940649 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.00939258 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.0093895 |
| MXRA8 | matrix-remodelling associated 8 | 0.0093822 |
| SPRR1B | small proline-rich protein 1B | 0.00938054 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00937323 |
| DENND5A | DENN/MADD domain containing 5A | 0.00937025 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00936095 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00935917 |
| GLO1 | glyoxalase I | 0.00934959 |
| PTGES | prostaglandin E synthase | 0.00932706 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00931797 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.00931615 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 0.00927208 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.00925478 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.00924233 |
| TMEM45A | transmembrane protein 45A | 0.0092377 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00923624 |
| CCDC86 | coiled-coil domain containing 86 | 0.00922665 |
| TPM1 | tropomyosin 1 (alpha) | 0.00918835 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00911567 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.00909039 |
| FOXF2 | forkhead box F2 | 0.00907943 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00904553 |
| FSTL1 | follistatin-like 1 | 0.00901858 |
| TMEM106C | transmembrane protein 106C | 0.00900985 |
| CHN2 | chimerin 2 | 0.00900161 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.00897671 |
| AXL | AXL receptor tyrosine kinase | 0.0089541 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00894662 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0089293 |
| NAV3 | neuron navigator 3 | 0.0089263 |
| HOXC10 | homeobox C10 | 0.00892233 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.00888283 |
| WDR19 | WD repeat domain 19 | 0.00887782 |
| HAL | histidine ammonia-lyase | 0.00886301 |
| TRIM14 | tripartite motif containing 14 | 0.00886208 |
| ZNF586 | zinc finger protein 586 | 0.00884799 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00884699 |
| KRT14 | keratin 14, type I | 0.00884554 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00883793 |
| CD37 | CD37 molecule | 0.00883366 |
| WWC3 | WWC family member 3 | 0.00882918 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.00881447 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00879157 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00879105 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00878658 |
| FAM117A | family with sequence similarity 117, member A | 0.00877499 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00876793 |
| USP48 | ubiquitin specific peptidase 48 | 0.0087573 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.00875588 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00875322 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00874447 |
| COL1A2 | collagen, type I, alpha 2 | 0.00873606 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.00872775 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 0.0087204 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 0.00870113 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) | 0.00868729 |
| BBX | bobby sox homolog (Drosophila) | 0.00868631 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.00868212 |
| LIMA1 | LIM domain and actin binding 1 | 0.00867101 |
| FBLN2 | fibulin 2 | 0.00866577 |
| RAB8A | RAB8A, member RAS oncogene family | 0.00866394 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.00865673 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0086547 |
| ACVR1B | activin A receptor, type IB | 0.00863115 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0086285 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00861596 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00861405 |
| EZR | ezrin | 0.00860307 |
| ABHD6 | abhydrolase domain containing 6 | 0.00859838 |
| MOK | MOK protein kinase | 0.00857416 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00856954 |
| KRT16 | keratin 16, type I | 0.00856678 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00856497 |
| AIM2 | absent in melanoma 2 | 0.00855569 |
| CD52 | CD52 molecule | 0.0085331 |
| PUM3 | pumilio RNA binding family member 3 | 0.00853033 |
| PXDC1 | PX domain containing 1 | 0.0085236 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | 0.0085103 |
| COMP | cartilage oligomeric matrix protein | 0.00849643 |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase | 0.00848896 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00847166 |
| PWWP3A | PWWP domain containing 3A, DNA repair factor | 0.00842131 |
| ADIRF | adipogenesis regulatory factor | 0.00841511 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00840636 |
| HOXC6 | homeobox C6 | 0.00839582 |
| OSR2 | odd-skipped related transciption factor 2 | 0.00838079 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | 0.00836815 |
| POLR3B | polymerase (RNA) III (DNA directed) polypeptide B | 0.00835713 |
| CLEC1B | C-type lectin domain family 1, member B | 0.00833702 |
| ENAH | enabled homolog (Drosophila) | 0.00833683 |
| ASPA | aspartoacylase | 0.00831512 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -0.0240175 |
| RGCC | regulator of cell cycle | -0.0236036 |
| EMP1 | epithelial membrane protein 1 | -0.0212401 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0210809 |
| FHL1 | four and a half LIM domains 1 | -0.0197517 |
| SPP1 | secreted phosphoprotein 1 | -0.0193109 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0177235 |
| TSPAN7 | tetraspanin 7 | -0.0168221 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0167647 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0167208 |
| NUP85 | nucleoporin 85kDa | -0.0165755 |
| CD200 | CD200 molecule | -0.0164847 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.0164614 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.0160827 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.0160129 |
| HOPX | HOP homeobox | -0.015851 |
| KRT7 | keratin 7, type II | -0.0157959 |
| TESC | tescalcin | -0.0157794 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0156256 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.0155924 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | -0.0152191 |
| HDGFL3 | HDGF like 3 | -0.015199 |
| HHEX | hematopoietically expressed homeobox | -0.0149033 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.0147434 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0145008 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.0143421 |
| PCLAF | PCNA clamp associated factor | -0.0143126 |
| AK4 | adenylate kinase 4 | -0.0143055 |
| ITGA6 | integrin, alpha 6 | -0.0142506 |
| PDE8B | phosphodiesterase 8B | -0.0142372 |
| H1-2 | H1.2 linker histone, cluster member | -0.0140967 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.0140683 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0139888 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0139219 |
| WT1 | Wilms tumor 1 | -0.0138939 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0138083 |
| MYBPC1 | myosin binding protein C, slow type | -0.0133435 |
| RAP2A | RAP2A, member of RAS oncogene family | -0.0133371 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.0133197 |
| S100P | S100 calcium binding protein P | -0.013252 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0131792 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0130881 |
| LTF | lactotransferrin | -0.0129677 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | -0.0129373 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.0128284 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0127909 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0127676 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.0127185 |
| MMP7 | matrix metallopeptidase 7 | -0.0126907 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0126401 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.01264 |
| FABP7 | fatty acid binding protein 7, brain | -0.0126177 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.0126174 |
| KIAA0226L | KIAA0226-like | -0.012435 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.0121605 |
| HIST1H2AE | histone cluster 1, H2ae | -0.0120766 |
| CALD1 | caldesmon 1 | -0.0119852 |
| YBX3 | Y box binding protein 3 | -0.0119671 |
| CCND2 | cyclin D2 | -0.0119311 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.0119173 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.0118404 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.0118303 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0118054 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0117808 |
| PRKCQ | protein kinase C, theta | -0.011767 |
| CD9 | CD9 molecule | -0.0116883 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0116349 |
| NMD3 | NMD3 ribosome export adaptor | -0.0115872 |
| SLN | sarcolipin | -0.0115808 |
| TPM4 | tropomyosin 4 | -0.0115531 |
| ACTB | actin, beta | -0.0114446 |
| TMEM126B | transmembrane protein 126B | -0.0114069 |
| OXTR | oxytocin receptor | -0.0113995 |
| CA2 | carbonic anhydrase II | -0.0113811 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.0113548 |
| ANXA3 | annexin A3 | -0.0111282 |
| PRKCH | protein kinase C, eta | -0.0111229 |
| CRIP2 | cysteine-rich protein 2 | -0.0111176 |
| EREG | epiregulin | -0.0110645 |
| SMAD4 | SMAD family member 4 | -0.0110502 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0110288 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.0110093 |
| ETV1 | ets variant 1 | -0.0109847 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.0109626 |
| GAB2 | GRB2-associated binding protein 2 | -0.0109626 |
| LPXN | leupaxin | -0.0109596 |
| SOX17 | SRY (sex determining region Y)-box 17 | -0.0109476 |
| BEX4 | brain expressed, X-linked 4 | -0.0109429 |
| DUT | deoxyuridine triphosphatase | -0.0109398 |
| EHF | ets homologous factor | -0.0109374 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | -0.0109325 |
| PLN | phospholamban | -0.0109129 |
| PNMA8A | PNMA family member 8A | -0.0108071 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0107683 |
| TYMS | thymidylate synthetase | -0.0107545 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.0107352 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0107338 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0107081 |
| ELAVL1 | ELAV like RNA binding protein 1 | -0.0106667 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.0106456 |
| KRT8 | keratin 8, type II | -0.0105832 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.010583 |
| MPO | myeloperoxidase | -0.0105683 |
| MED6 | mediator complex subunit 6 | -0.010475 |
| NES | nestin | -0.0104641 |
| KLK5 | kallikrein-related peptidase 5 | -0.0104584 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.0104432 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.0104424 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.0104295 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.0103683 |
| SELENOT | selenoprotein T | -0.0103665 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.0103452 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.0103241 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 | -0.010324 |
| SNX5 | sorting nexin 5 | -0.0103003 |
| ATG5 | autophagy related 5 | -0.0102917 |
| CFI | complement factor I | -0.0102883 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0102754 |
| PLVAP | plasmalemma vesicle associated protein | -0.0102298 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0102138 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.0102112 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.0102102 |
| ITM2A | integral membrane protein 2A | -0.0102091 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0101993 |
| ACYP2 | acylphosphatase 2, muscle type | -0.0101652 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.010163 |
| EMX2 | empty spiracles homeobox 2 | -0.0101443 |
| TMEM100 | transmembrane protein 100 | -0.0101283 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.0101016 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.0100819 |
| CCN2 | cellular communication network factor 2 | -0.010003 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | -0.0099957 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00998329 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00994125 |
| PDHX | pyruvate dehydrogenase complex, component X | -0.00993368 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00993156 |
| ELANE | elastase, neutrophil expressed | -0.00989973 |
| POSTN | periostin, osteoblast specific factor | -0.00987197 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0098674 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00986234 |
| TCL1A | T-cell leukemia/lymphoma 1A | -0.00983163 |
| DNTT | DNA nucleotidylexotransferase | -0.00983119 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00982929 |
| EGR2 | early growth response 2 | -0.00979537 |
| MMP8 | matrix metallopeptidase 8 | -0.00977983 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00976579 |
| SERPINB7 | serpin peptidase inhibitor, clade B (ovalbumin), member 7 | -0.00974105 |
| CLDN8 | claudin 8 | -0.00971113 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00970687 |
| PRNP | prion protein | -0.00970664 |
| FZD6 | frizzled class receptor 6 | -0.00970423 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.00969932 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.00968559 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | -0.0096763 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00966374 |
| LDB3 | LIM domain binding 3 | -0.009614 |
| TRAF3IP2 | TRAF3 interacting protein 2 | -0.00958792 |
| FOLR1 | folate receptor 1 (adult) | -0.0095877 |
| SALL1 | spalt-like transcription factor 1 | -0.00958367 |
| PCP4 | Purkinje cell protein 4 | -0.00956123 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00952401 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.00949807 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00948671 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -0.00947165 |
| DUOX2 | dual oxidase 2 | -0.00945662 |
| ZMYND11 | zinc finger, MYND-type containing 11 | -0.00944902 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -0.0094458 |
| NDC1 | NDC1 transmembrane nucleoporin | -0.0094284 |
| FERMT1 | fermitin family member 1 | -0.00940634 |
| CTTN | cortactin | -0.00936513 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | -0.00936069 |
| PEG3 | paternally expressed 3 | -0.00935184 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.00933773 |
| MRPS28 | mitochondrial ribosomal protein S28 | -0.00931279 |
| FGG | fibrinogen gamma chain | -0.00928379 |
| CANX | calnexin | -0.00927354 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.00926313 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00926166 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -0.0092568 |
| PRSS21 | protease, serine, 21 (testisin) | -0.00925614 |
| ARRB2 | arrestin, beta 2 | -0.00925273 |
| BCL2A1 | BCL2-related protein A1 | -0.00922957 |
| EIF5 | eukaryotic translation initiation factor 5 | -0.00921398 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | -0.00921088 |
| PDE8A | phosphodiesterase 8A | -0.00920382 |
| GPHN | gephyrin | -0.00919758 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00919296 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.00918752 |
| PDAP1 | PDGFA associated protein 1 | -0.00914314 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00905245 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00903841 |
| AKAP1 | A kinase (PRKA) anchor protein 1 | -0.00900353 |
| LBH | limb bud and heart development | -0.00899495 |
| MAGEA3 | melanoma antigen family A3 | -0.00899345 |
| MMP12 | matrix metallopeptidase 12 | -0.00898869 |
| DIPK1A | divergent protein kinase domain 1A | -0.0089856 |
| MAGEA12 | melanoma antigen family A12 | -0.00898557 |
| CD58 | CD58 molecule | -0.0089723 |
| KPNA3 | karyopherin alpha 3 (importin alpha 4) | -0.00893742 |
| THBS1 | thrombospondin 1 | -0.00893171 |
| CLDN1 | claudin 1 | -0.00891909 |
| ALG5 | ALG5, dolichyl-phosphate beta-glucosyltransferase | -0.00891892 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | -0.00891848 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 | -0.00891796 |
| MSLN | mesothelin | -0.00890911 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00889716 |
| CREM | cAMP responsive element modulator | -0.0088851 |
| MEX3C | mex-3 RNA binding family member C | -0.00883915 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.00883391 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.0088328 |
| BANF1 | barrier to autointegration factor 1 | -0.00882621 |
| TBXA2R | thromboxane A2 receptor | -0.00881456 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00881315 |
| COMMD10 | COMM domain containing 10 | -0.00880958 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00879289 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00876931 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00874274 |
| A2M | alpha-2-macroglobulin | -0.00872765 |
| KCTD14 | potassium channel tetramerization domain containing 14 | -0.00870985 |
| GMFG | glia maturation factor, gamma | -0.00870406 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | -0.00868769 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | -0.00868258 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00867924 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00867257 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.00864724 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00864394 |
| TTN | titin | -0.00863117 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.00862782 |
| MFAP5 | microfibrillar associated protein 5 | -0.00861923 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00860857 |
| ACP1 | acid phosphatase 1, soluble | -0.00860297 |
| CP | ceruloplasmin (ferroxidase) | -0.00860018 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) | -0.00859427 |
| FBXO11 | F-box protein 11 | -0.00859308 |
| MAOA | monoamine oxidase A | -0.00858202 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -0.00857124 |
| MLXIP | MLX interacting protein | -0.00856742 |
| HIRA | histone cell cycle regulator | -0.00856283 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 | -0.00854715 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00854563 |
| ADM | adrenomedullin | -0.00849556 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00846524 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | -0.00844998 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00844781 |
| ZNF277 | zinc finger protein 277 | -0.00844537 |
| SLC43A3 | solute carrier family 43, member 3 | -0.00844473 |
