BRCA1 A complex Gene Set

Dataset CORUM Protein Complexes
Category structural or functional annotations
Type protein complex
Description A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites. (Gene Ontology, GO_0070531)
External Link http://mips.helmholtz-muenchen.de/genre/proj/corum/complexdetails.html?id=2786
Similar Terms
Downloads & Tools

Genes

4 proteins in the BRCA1 A complex protein complex from the CORUM Protein Complexes dataset.

Symbol Name
BARD1 BRCA1 associated RING domain 1
BRCA1 breast cancer 1, early onset
FAM175A family with sequence similarity 175, member A
UIMC1 ubiquitin interaction motif containing 1