| Dataset | CORUM Protein Complexes |
| Category | structural or functional annotations |
| Type | protein complex |
| Description | A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint. (Gene Ontology, GO_0070533) |
| External Link | http://mips.helmholtz-muenchen.de/genre/proj/corum/complexdetails.html?id=2787 |
| Similar Terms | |
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4 proteins in the BRCA1 C complex protein complex from the CORUM Protein Complexes dataset.
