BRCA2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description breast cancer 2, early onset|Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008] (NCBI Entrez Gene Database, 675)
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Genes

563 genes differentially expressed following the BRCA2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PTGES prostaglandin E synthase 2.52531
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa 2.52531
MED25 mediator complex subunit 25 2.52531
SLC35E4 solute carrier family 35, member E4 2.52531
ZNF550 zinc finger protein 550 2.52531
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 2.52531
ADSS1 adenylosuccinate synthase 1 2.52531
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 2.52531
IQCH IQ motif containing H 2.52531
AADAT aminoadipate aminotransferase 2.52531
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 2.52531
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 2.52531
MTFR1L mitochondrial fission regulator 1-like 2.52531
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 2.52531
TMEM201 transmembrane protein 201 2.52531
ZNF7 zinc finger protein 7 2.52531
IFT74 intraflagellar transport 74 2.52531
MCMDC2 minichromosome maintenance domain containing 2 2.52531
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 2.52531
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.52531
FAM217B family with sequence similarity 217, member B 2.52531
BTBD17 BTB (POZ) domain containing 17 2.52531
GCH1 GTP cyclohydrolase 1 2.52531
KLHDC7A kelch domain containing 7A 2.52531
MAP3K19 mitogen-activated protein kinase kinase kinase 19 2.52531
DMWD dystrophia myotonica, WD repeat containing 2.52531
HROB homologous recombination factor with OB-fold 2.52531
TMEM52 transmembrane protein 52 2.52531
FAM89B family with sequence similarity 89, member B 2.52531
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 2.52531
SLC35F4 solute carrier family 35, member F4 2.52531
MARCHF4 membrane associated ring-CH-type finger 4 2.52531
MADD MAP-kinase activating death domain 2.52531
TRAPPC2B trafficking protein particle complex 2B 2.52531
SCARA3 scavenger receptor class A, member 3 2.52531
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 2.52531
IPO4 importin 4 2.52531
B3GAT1 beta-1,3-glucuronyltransferase 1 2.52531
CCDC200 coiled-coil domain containing 200 2.52531
SMIM13 small integral membrane protein 13 2.52531
MYO15A myosin XVA 2.52531
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 2.52531
AQP11 aquaporin 11 2.52531
SLC38A7 solute carrier family 38, member 7 2.52531
EXOSC4 exosome component 4 2.52531
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 2.51659
TSEN34 TSEN34 tRNA splicing endonuclease subunit 2.30499
TSHZ3 teashirt zinc finger homeobox 3 2.26879
CYB5R1 cytochrome b5 reductase 1 2.24036
PCOLCE procollagen C-endopeptidase enhancer 2.24036
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 2.24036
TANGO2 transport and golgi organization 2 homolog (Drosophila) 2.24036
PCDHGA10 protocadherin gamma subfamily A, 10 2.24036
OGN osteoglycin 2.24036
ZFYVE1 zinc finger, FYVE domain containing 1 2.24036
RELL2 RELT-like 2 2.24036
CRYZ crystallin, zeta (quinone reductase) 2.24036
C1ORF50 chromosome 1 open reading frame 50 2.24036
FGF20 fibroblast growth factor 20 2.24036
COLEC10 collectin sub-family member 10 (C-type lectin) 2.24036
TMEM144 transmembrane protein 144 2.24036
GPR162 G protein-coupled receptor 162 2.24036
SPAG17 sperm associated antigen 17 2.24036
ZNF284 zinc finger protein 284 2.24036
YOD1 YOD1 deubiquitinase 2.24036
LMO2 LIM domain only 2 (rhombotin-like 1) 2.24036
IL17RC interleukin 17 receptor C 2.24036
MEF2B myocyte enhancer factor 2B 2.24036
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase 2.24036
TUBB1 tubulin, beta 1 class VI 2.24036
SFXN3 sideroflexin 3 2.24036
SIRT2 sirtuin 2 2.24036
PLXNB1 plexin B1 2.24036
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 2.24036
SLC23A3 solute carrier family 23, member 3 2.24036
ARSA arylsulfatase A 2.24036
C12ORF75 chromosome 12 open reading frame 75 2.24036
SYCE2 synaptonemal complex central element protein 2 2.24036
TRPV2 transient receptor potential cation channel, subfamily V, member 2 2.24036
PARM1 prostate androgen-regulated mucin-like protein 1 2.24036
GFPT2 glutamine-fructose-6-phosphate transaminase 2 2.24036
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 2.24036
FN3KRP fructosamine 3 kinase related protein 2.24036
VSTM2L V-set and transmembrane domain containing 2 like 2.24036
CD163L1 CD163 molecule-like 1 2.24036
ATG9B autophagy related 9B 2.24036
RAB18 RAB18, member RAS oncogene family 2.24036
ELMO3 engulfment and cell motility 3 2.24036
PKP2 plakophilin 2 2.24036
ZNF469 zinc finger protein 469 2.24036
PSD3 pleckstrin and Sec7 domain containing 3 2.24036
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.24036
UNC13D unc-13 homolog D (C. elegans) 2.24036
PNMA2 paraneoplastic Ma antigen 2 2.24036
ERN1 endoplasmic reticulum to nucleus signaling 1 2.24036
VEPH1 ventricular zone expressed PH domain-containing 1 2.24036
IQCC IQ motif containing C 2.24036
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 2.24036
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 2.24036
TRIM15 tripartite motif containing 15 2.24036
LIPG lipase, endothelial 2.24036
MIMS2 mitochondrial inner membrane scaffold 2 2.24036
TAMALIN trafficking regulator and scaffold protein tamalin 2.24036
H2AC8 H2A clustered histone 8 2.24036
PAK5 p21 (RAC1) activated kinase 5 2.24036
TMEM94 transmembrane protein 94 2.24036
PNMA8A PNMA family member 8A 2.24036
COQ8A coenzyme Q8A 2.24036
ETFRF1 electron transfer flavoprotein regulatory factor 1 2.24036
NCKIPSD NCK interacting protein with SH3 domain 2.24036
FKBP9 FK506 binding protein 9, 63 kDa 2.24036
ZNF527 zinc finger protein 527 2.24036
HTRA1 HtrA serine peptidase 1 2.24036
SPEM1 spermatid maturation 1 2.24036
DUSP5 dual specificity phosphatase 5 2.24036
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase 2.24036
PAN2 PAN2 poly(A) specific ribonuclease subunit 2.24036
TLCD5 TLC domain containing 5 2.24036
PHETA2 PH domain containing endocytic trafficking adaptor 2 2.24036
STPG4 sperm-tail PG-rich repeat containing 4 2.24036
KRABD3 KRAB domain containing 3 2.24036
DORIP1 dopamine receptor interacting protein 1 2.24036
TEX53 testis expressed 53 2.24036
SMIM47 small integral membrane protein 47 2.24036
REELD1 reeler domain containing 1 2.24036
SAXO4 stabilizer of axonemal microtubules 4 2.24036
FNDC10 fibronectin type III domain containing 10 2.24036
ACP7 acid phosphatase 7, tartrate resistant (putative) 2.24036
IHO1 interactor of HORMAD1 1 2.24036
MARCHF11 membrane associated ring-CH-type finger 11 2.24036
TEX13C TEX13 family member C 2.24036
H2BC17 H2B clustered histone 17 2.24036
INSYN2B inhibitory synaptic factor family member 2B 2.24036
ITPRID1 ITPR interacting domain containing 1 2.24036
GARIN1B golgi associated RAB2 interactor 1B 2.24036
CASZ1 castor zinc finger 1 2.24036
TMPRSS9 transmembrane protease, serine 9 2.24036
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 2.24036
ZNF772 zinc finger protein 772 2.24036
ZNF777 zinc finger protein 777 2.24036
PRKCD protein kinase C, delta 2.24036
PRKCE protein kinase C, epsilon 2.24036
DEPDC7 DEP domain containing 7 2.24036
TGFBR3L transforming growth factor, beta receptor III-like 2.24036
GLA galactosidase, alpha 2.24036
LRRC8C leucine rich repeat containing 8 family, member C 2.24036
ARHGAP9 Rho GTPase activating protein 9 2.24036
MEDAG mesenteric estrogen-dependent adipogenesis 2.24036
RHOBTB2 Rho-related BTB domain containing 2 2.24036
ZBTB16 zinc finger and BTB domain containing 16 2.24036
CLDN1 claudin 1 2.24036
COX6B2 cytochrome c oxidase subunit VIb polypeptide 2 (testis) 2.24036
C1QL1 complement component 1, q subcomponent-like 1 2.24036
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.24036
PRR16 proline rich 16 2.24036
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 2.24036
TSPAN2 tetraspanin 2 2.24036
MFSD1 major facilitator superfamily domain containing 1 2.24036
MYB v-myb avian myeloblastosis viral oncogene homolog 2.24036
STAC2 SH3 and cysteine rich domain 2 2.24036
LTF lactotransferrin 2.24036
ZNF687 zinc finger protein 687 2.24036
ZNF688 zinc finger protein 688 2.24036
PMP22 peripheral myelin protein 22 2.24036
NPIPB4 nuclear pore complex interacting protein family, member B4 2.24036
ADPRH ADP-ribosylarginine hydrolase 2.24036
RBM48 RNA binding motif protein 48 2.24036
RGS22 regulator of G-protein signaling 22 2.24036
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 2.24036
HSF2BP heat shock transcription factor 2 binding protein 2.24036
C5ORF58 chromosome 5 open reading frame 58 2.24036
MTHFSD methenyltetrahydrofolate synthetase domain containing 2.24036
TMEM101 transmembrane protein 101 2.24036
FNDC5 fibronectin type III domain containing 5 2.24036
NAIF1 nuclear apoptosis inducing factor 1 2.24036
FRRS1L ferric-chelate reductase 1-like 2.24036
ARHGAP22 Rho GTPase activating protein 22 2.24036
ANKLE1 ankyrin repeat and LEM domain containing 1 2.24036
AVPI1 arginine vasopressin-induced 1 2.24036
ADNP activity-dependent neuroprotector homeobox 2.24036
CNPY4 canopy FGF signaling regulator 4 2.24036
CT55 cancer/testis antigen 55 2.24036
RAB40B RAB40B, member RAS oncogene family 2.24036
PLAU plasminogen activator, urokinase 2.24036
EDN3 endothelin 3 2.24036
MYBBP1A MYB binding protein (P160) 1a 2.24036
ADGRA2 adhesion G protein-coupled receptor A2 2.24036
DPRX divergent-paired related homeobox 2.24036
ZNFX1 zinc finger, NFX1-type containing 1 2.24036
ACBD4 acyl-CoA binding domain containing 4 2.24036
PAQR4 progestin and adipoQ receptor family member IV 2.24036
ZNF214 zinc finger protein 214 2.24036
FAM53A family with sequence similarity 53, member A 2.24036
CACFD1 calcium channel flower domain containing 1 2.24036
RHBG Rh family, B glycoprotein (gene/pseudogene) 2.24036
PRRX2 paired related homeobox 2 2.24036
TFIP11 tuftelin interacting protein 11 2.24036
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 2.24036
ANKRD13B ankyrin repeat domain 13B 2.24036
CSAD cysteine sulfinic acid decarboxylase 2.24036
ZFP69 ZFP69 zinc finger protein 2.24036
RORC RAR-related orphan receptor C 2.24036
OMG oligodendrocyte myelin glycoprotein 2.24036
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 2.24036
DTWD1 DTW domain containing 1 2.24036
C17ORF107 chromosome 17 open reading frame 107 2.24036
CACTIN cactin, spliceosome C complex subunit 2.24036
F12 coagulation factor XII (Hageman factor) 2.24036
MORN1 MORN repeat containing 1 2.24036
OR4D1 olfactory receptor, family 4, subfamily D, member 1 2.24036
CKMT1A creatine kinase, mitochondrial 1A 2.24036
PLCD3 phospholipase C, delta 3 2.24036
RGS3 regulator of G-protein signaling 3 2.24036
TRPT1 tRNA phosphotransferase 1 2.24036
RIMKLA ribosomal modification protein rimK-like family member A 2.24036
TMUB2 transmembrane and ubiquitin-like domain containing 2 2.24036
RIN2 Ras and Rab interactor 2 2.24036
ASXL3 additional sex combs like transcriptional regulator 3 2.24036
HES1 hes family bHLH transcription factor 1 2.24036
SHANK3 SH3 and multiple ankyrin repeat domains 3 2.24036
ADAM12 ADAM metallopeptidase domain 12 2.24036
TEX22 testis expressed 22 2.24036
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 2.24036
FBXL14 F-box and leucine-rich repeat protein 14 2.24036
THEMIS2 thymocyte selection associated family member 2 2.24036
TAPBPL TAP binding protein-like 2.24036
ZNF548 zinc finger protein 548 2.24036
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 2.24036
CALHM2 calcium homeostasis modulator 2 2.24036
FAM20A family with sequence similarity 20, member A 2.24036
SRP54 signal recognition particle 54kDa 2.24036
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 2.24036
SLC29A4 solute carrier family 29 (equilibrative nucleoside transporter), member 4 2.24036
PCDHGA6 protocadherin gamma subfamily A, 6 2.24036
LIMCH1 LIM and calponin homology domains 1 2.24036
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1 2.24036
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 2.24036
CR1L complement component (3b/4b) receptor 1-like 2.24036
IL18 interleukin 18 2.24036
SEC14L5 SEC14-like 5 (S. cerevisiae) 2.24036
PDZRN4 PDZ domain containing ring finger 4 2.24036
FGR FGR proto-oncogene, Src family tyrosine kinase 2.24036
PHACTR3 phosphatase and actin regulator 3 2.24036
FSCN3 fascin actin-bundling protein 3, testicular 2.24036
VSX1 visual system homeobox 1 2.24036
MPZ myelin protein zero 2.24036
CLCN4 chloride channel, voltage-sensitive 4 2.24036
TMC1 transmembrane channel-like 1 2.24036
TCEAL1 transcription elongation factor A (SII)-like 1 2.24036
CENPF centromere protein F, 350/400kDa 2.24036
ANKH ANKH inorganic pyrophosphate transport regulator 2.24036
PROM2 prominin 2 2.24036
SP2 Sp2 transcription factor 2.24036
MAP3K8 mitogen-activated protein kinase kinase kinase 8 2.24036
HRC histidine rich calcium binding protein 2.24036
GRM8 glutamate receptor, metabotropic 8 2.24036
NRSN2 neurensin 2 2.24036
RBP7 retinol binding protein 7, cellular 2.24036
CDK12 cyclin-dependent kinase 12 2.24036
CRYGS crystallin, gamma S 2.24036
LEMD1 LEM domain containing 1 2.24036
FOXB1 forkhead box B1 2.24036
LEFTY2 left-right determination factor 2 2.24036
CA13 carbonic anhydrase XIII 2.24036
TMEM151B transmembrane protein 151B 2.24036
KCNIP4 Kv channel interacting protein 4 2.24036
ZNF454 zinc finger protein 454 2.24036
FOXL2NB FOXL2 neighbor 2.24036
ENG endoglin 2.24036
PRSS35 protease, serine, 35 2.24036
NEB nebulin 2.24036
ZBTB39 zinc finger and BTB domain containing 39 2.24036
PCGF5 polycomb group ring finger 5 2.24036
PLK5 polo-like kinase 5 2.24036
ZNF691 zinc finger protein 691 2.24036
KAT2A K(lysine) acetyltransferase 2A 2.24036
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 2.24036
GPATCH11 G patch domain containing 11 2.24036
KCNK10 potassium channel, two pore domain subfamily K, member 10 2.24036
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 2.24036
PYGB phosphorylase, glycogen; brain 2.24036
TLCD2 TLC domain containing 2 2.24036
VWC2 von Willebrand factor C domain containing 2 2.24036
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 2.24036
ANGPTL2 angiopoietin-like 2 2.24036
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.24036
LRRC45 leucine rich repeat containing 45 2.24036
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 2.24036
NRG2 neuregulin 2 2.24036
SPATC1L spermatogenesis and centriole associated 1-like 2.24036
PNMT phenylethanolamine N-methyltransferase 2.24036
ZNF391 zinc finger protein 391 2.24036
CHRM2 cholinergic receptor, muscarinic 2 2.24036
POLM polymerase (DNA directed), mu 2.24036
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 2.24036
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 2.21523
DNM1L dynamin 1-like 2.18868
SEC11A SEC11 homolog A (S. cerevisiae) 2.18066
MPPED2 metallophosphoesterase domain containing 2 2.15324
POLR3B polymerase (RNA) III (DNA directed) polypeptide B 2.15324
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 2.153
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 2.13451
AUNIP aurora kinase A and ninein interacting protein 2.10786
CTDNEP1 CTD nuclear envelope phosphatase 1 2.1048
SGCE sarcoglycan, epsilon 2.08574
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 2.04209
STX3 syntaxin 3 2.04129
RGPD2 RANBP2-like and GRIP domain containing 2 2.04129
SCD5 stearoyl-CoA desaturase 5 2.03967
TEAD3 TEA domain family member 3 2.03967
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 2.03967
AMACR alpha-methylacyl-CoA racemase 2.03967
BRSK1 BR serine/threonine kinase 1 2.03967
C1ORF94 chromosome 1 open reading frame 94 2.03967
NRXN3 neurexin 3 2.03967
RHBDL2 rhomboid, veinlet-like 2 (Drosophila) 2.03967
MARVELD2 MARVEL domain containing 2 2.02642
NF1 neurofibromin 1 2.02158
HMGN5 high mobility group nucleosome binding domain 5 2.01106
TSC22D4 TSC22 domain family, member 4 2.00222
GAPVD1 GTPase activating protein and VPS9 domains 1 2.00222
SCAMP3 secretory carrier membrane protein 3 2.00222
SMAD7 SMAD family member 7 2.00222
FRMD6 FERM domain containing 6 2.00222
CES2 carboxylesterase 2 2.00222
CCDC138 coiled-coil domain containing 138 2.00222
STAU2 staufen double-stranded RNA binding protein 2 2.00222
CDH18 cadherin 18, type 2 2.00222
TRIM21 tripartite motif containing 21 2.00222
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 2.00222
REPS2 RALBP1 associated Eps domain containing 2 2.00222

decreased expression

Symbol Name Standardized Value
ERGIC2 ERGIC and golgi 2 -2.52531
RRP1 ribosomal RNA processing 1 -2.52531
FBXW8 F-box and WD repeat domain containing 8 -2.52531
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -2.52531
ZNF791 zinc finger protein 791 -2.52531
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide -2.52531
ZMIZ1 zinc finger, MIZ-type containing 1 -2.52531
PCBP3 poly(rC) binding protein 3 -2.52531
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) -2.52531
LDHB lactate dehydrogenase B -2.52531
SAC3D1 SAC3 domain containing 1 -2.52531
MIER2 mesoderm induction early response 1, family member 2 -2.52531
DDA1 DET1 and DDB1 associated 1 -2.52531
MRPL23 mitochondrial ribosomal protein L23 -2.52531
R3HCC1L R3H domain and coiled-coil containing 1-like -2.52531
GEMIN6 gem (nuclear organelle) associated protein 6 -2.52531
MSRB1 methionine sulfoxide reductase B1 -2.52531
MT1H metallothionein 1H -2.52531
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 -2.52531
PANK3 pantothenate kinase 3 -2.52531
LPAR3 lysophosphatidic acid receptor 3 -2.52531
TPM1 tropomyosin 1 (alpha) -2.47177
THUMPD3 THUMP domain containing 3 -2.30906
ISCA2 iron-sulfur cluster assembly 2 -2.30906
AEN apoptosis enhancing nuclease -2.30499
APLF aprataxin and PNKP like factor -2.30499
LTN1 listerin E3 ubiquitin protein ligase 1 -2.30499
USP4 ubiquitin specific peptidase 4 (proto-oncogene) -2.28373
GTPBP2 GTP binding protein 2 -2.26879
PDGFA platelet-derived growth factor alpha polypeptide -2.26879
EPC2 enhancer of polycomb homolog 2 (Drosophila) -2.26879
RNF217 ring finger protein 217 -2.26879
POT1 protection of telomeres 1 -2.26879
EGLN3 egl-9 family hypoxia-inducible factor 3 -2.26879
ANXA11 annexin A11 -2.26879
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) -2.26879
SMIM11 small integral membrane protein 11 -2.26879
COPS5 COP9 signalosome subunit 5 -2.26879
MBD3 methyl-CpG binding domain protein 3 -2.26879
LRRC28 leucine rich repeat containing 28 -2.26879
SPINDOC spindlin interactor and repressor of chromatin binding -2.24036
KLHL25 kelch-like family member 25 -2.24036
KLHL29 kelch-like family member 29 -2.24036
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 -2.24036
SNX12 sorting nexin 12 -2.24036
MICU3 mitochondrial calcium uptake family, member 3 -2.24036
ATP5MJ ATP synthase membrane subunit j -2.24036
SH3GL1 SH3-domain GRB2-like 1 -2.24036
CAPN7 calpain 7 -2.24036
CPOX coproporphyrinogen oxidase -2.24036
KCTD7 potassium channel tetramerization domain containing 7 -2.24036
NEXMIF neurite extension and migration factor -2.24036
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 -2.24036
H2AC14 H2A clustered histone 14 -2.24036
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 -2.24036
MICOS10 mitochondrial contact site and cristae organizing system subunit 10 -2.24036
MAVS mitochondrial antiviral signaling protein -2.24036
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase -2.24036
ATPSCKMT ATP synthase c subunit lysine N-methyltransferase -2.24036
PRMT8 protein arginine methyltransferase 8 -2.24036
PRUNE1 prune exopolyphosphatase 1 -2.24036
TRPM4 transient receptor potential cation channel, subfamily M, member 4 -2.24036
REPIN1 replication initiator 1 -2.24036
IQCK IQ motif containing K -2.24036
ZDHHC5 zinc finger, DHHC-type containing 5 -2.24036
TP53RK TP53 regulating kinase -2.24036
FLYWCH2 FLYWCH family member 2 -2.24036
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -2.24036
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 -2.24036
MAX MYC associated factor X -2.24036
BICD2 bicaudal D homolog 2 (Drosophila) -2.24036
SRSF2 serine/arginine-rich splicing factor 2 -2.24036
AP1B1 adaptor-related protein complex 1, beta 1 subunit -2.24036
NHSL2 NHS-like 2 -2.24036
SLC16A4 solute carrier family 16, member 4 -2.24036
SHROOM2 shroom family member 2 -2.24036
C8ORF76 chromosome 8 open reading frame 76 -2.24036
TTC7A tetratricopeptide repeat domain 7A -2.24036
MEAK7 MTOR associated protein, eak-7 homolog -2.24036
SENP8 SUMO/sentrin specific peptidase family member 8 -2.24036
PNPLA4 patatin-like phospholipase domain containing 4 -2.24036
RBM5 RNA binding motif protein 5 -2.24036
ACIN1 apoptotic chromatin condensation inducer 1 -2.24036
MUC3A mucin 3A, cell surface associated -2.24036
CCSER1 coiled-coil serine-rich protein 1 -2.24036
ZDHHC18 zinc finger, DHHC-type containing 18 -2.24036
TRIM23 tripartite motif containing 23 -2.24036
LRIF1 ligand dependent nuclear receptor interacting factor 1 -2.24036
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 -2.24036
GOLT1B golgi transport 1B -2.24036
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 -2.24036
CDT1 chromatin licensing and DNA replication factor 1 -2.24036
IFT88 intraflagellar transport 88 -2.24036
MTIF3 mitochondrial translational initiation factor 3 -2.24036
SUFU suppressor of fused homolog (Drosophila) -2.24036
KIF3B kinesin family member 3B -2.24036
MRPL44 mitochondrial ribosomal protein L44 -2.24036
AAR2 AAR2 splicing factor homolog (S. cerevisiae) -2.24036
WDR3 WD repeat domain 3 -2.24036
OXA1L oxidase (cytochrome c) assembly 1-like -2.24036
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 -2.24036
NSUN4 NOP2/Sun domain family, member 4 -2.24036
ERCC5 excision repair cross-complementation group 5 -2.24036
SOGA1 suppressor of glucose, autophagy associated 1 -2.24036
DBR1 debranching RNA lariats 1 -2.24036
RAB39A RAB39A, member RAS oncogene family -2.24036
TMEM67 transmembrane protein 67 -2.24036
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) -2.24036
WDR46 WD repeat domain 46 -2.24036
RHBDF2 rhomboid 5 homolog 2 (Drosophila) -2.24036
LAPTM4A lysosomal protein transmembrane 4 alpha -2.24036
RPL6 ribosomal protein L6 -2.24036
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 -2.24036
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -2.24036
SIAH2 siah E3 ubiquitin protein ligase 2 -2.24036
FJX1 four jointed box 1 (Drosophila) -2.24036
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -2.24036
UHRF1 ubiquitin-like with PHD and ring finger domains 1 -2.24036
HDGF hepatoma-derived growth factor -2.24036
FAM50A family with sequence similarity 50, member A -2.24036
MAP3K21 mitogen-activated protein kinase kinase kinase 21 -2.23594
TM9SF2 transmembrane 9 superfamily member 2 -2.23112
MFAP2 microfibrillar-associated protein 2 -2.22362
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 -2.18174
PACS2 phosphofurin acidic cluster sorting protein 2 -2.17238
RP9 retinitis pigmentosa 9 (autosomal dominant) -2.17238
NIP7 NIP7, nucleolar pre-rRNA processing protein -2.17238
RUBCN rubicon autophagy regulator -2.17238
CCP110 centriolar coiled coil protein 110kDa -2.17238
GHITM growth hormone inducible transmembrane protein -2.13751
FNTB farnesyltransferase, CAAX box, beta -2.10797
XKR4 XK, Kell blood group complex subunit-related family, member 4 -2.10797
TFE3 transcription factor binding to IGHM enhancer 3 -2.10797
ARHGAP39 Rho GTPase activating protein 39 -2.10797
TRMT5 tRNA methyltransferase 5 -2.10797
CXCL12 chemokine (C-X-C motif) ligand 12 -2.10797
C5ORF24 chromosome 5 open reading frame 24 -2.10797
ACTC1 actin, alpha, cardiac muscle 1 -2.10797
TSLIG2 tRNA splicing ligase complex subunit 2 -2.10797
RPL22 ribosomal protein L22 -2.10529
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.09353
BID BH3 interacting domain death agonist -2.07581
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) -2.07363
PRPF39 pre-mRNA processing factor 39 -2.07363
MT1X metallothionein 1X -2.07363
MIB2 mindbomb E3 ubiquitin protein ligase 2 -2.07363
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 -2.0731
MRPS18A mitochondrial ribosomal protein S18A -2.06626
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -2.06373
ELMOD2 ELMO/CED-12 domain containing 2 -2.06169
WDR47 WD repeat domain 47 -2.06169
ZNF684 zinc finger protein 684 -2.06169
ZDHHC16 zinc finger, DHHC-type containing 16 -2.06169
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor -2.06169
ZNF836 zinc finger protein 836 -2.06169
PIP4P1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 -2.06169
MBOAT7 membrane bound O-acyltransferase domain containing 7 -2.06169
ZNF320 zinc finger protein 320 -2.06169
YDJC YdjC homolog (bacterial) -2.06169
RAB35 RAB35, member RAS oncogene family -2.06169
SHROOM4 shroom family member 4 -2.06169
CDC26 cell division cycle 26 -2.05165
AIDA axin interactor, dorsalization associated -2.04209
NOM1 nucleolar protein with MIF4G domain 1 -2.04129
HSPB11 heat shock protein family B (small), member 11 -2.04129
OTULINL OTU deubiquitinase with linear linkage specificity like -2.00222
TZMP1 transition zone microprotein 1 -2.00222
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) -2.00222
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 -2.00222
MTARC2 mitochondrial amidoxime reducing component 2 -2.00222
PGCKA1 PDCD10 and GCKIII kinases associated 1 -2.00222
CFAP46 cilia and flagella associated protein 46 -2.00222
TMEM163 transmembrane protein 163 -2.00222
STEEP1 STING1 ER exit protein 1 -2.00222
NOSTRIN nitric oxide synthase trafficking -2.00222
COMMD9 COMM domain containing 9 -2.00222
ANO2 anoctamin 2, calcium activated chloride channel -2.00222
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 -2.00222
TRAPPC2 trafficking protein particle complex 2 -2.00222
KCTD17 potassium channel tetramerization domain containing 17 -2.00222
ZNF512B zinc finger protein 512B -2.00222
SYT11 synaptotagmin XI -2.00222
WDR13 WD repeat domain 13 -2.00222
OPTN optineurin -2.00222
ZNF514 zinc finger protein 514 -2.00222
FURIN furin (paired basic amino acid cleaving enzyme) -2.00222
GADD45A growth arrest and DNA-damage-inducible, alpha -2.00222
MXD4 MAX dimerization protein 4 -2.00222
LAD1 ladinin 1 -2.00222
SPPL2B signal peptide peptidase like 2B -2.00222
ACBD7 acyl-CoA binding domain containing 7 -2.00222
LMBRD2 LMBR1 domain containing 2 -2.00222
ACTR8 ARP8 actin-related protein 8 homolog (yeast) -2.00222
G6PD glucose-6-phosphate dehydrogenase -2.00222
PHF1 PHD finger protein 1 -2.00222
TMEM70 transmembrane protein 70 -2.00222
ZSCAN21 zinc finger and SCAN domain containing 21 -2.00222
PITRM1 pitrilysin metallopeptidase 1 -2.00222
ZFP30 ZFP30 zinc finger protein -2.00222
NOS1 nitric oxide synthase 1 (neuronal) -2.00222
CCDC28B coiled-coil domain containing 28B -2.00222
UBOX5 U-box domain containing 5 -2.00222
STARD4 StAR-related lipid transfer (START) domain containing 4 -2.00222
NEURL1B neuralized E3 ubiquitin protein ligase 1B -2.00222
FAM120B family with sequence similarity 120B -2.00222
DTD2 D-tyrosyl-tRNA deacylase 2 (putative) -2.00222
KCTD6 potassium channel tetramerization domain containing 6 -2.00222
TRIM26 tripartite motif containing 26 -2.00222
ZNF552 zinc finger protein 552 -2.00222
FYCO1 FYVE and coiled-coil domain containing 1 -2.00222
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) -2.00222
AKT1S1 AKT1 substrate 1 (proline-rich) -2.00222
PAPLN papilin, proteoglycan-like sulfated glycoprotein -2.00222
ZNF174 zinc finger protein 174 -2.00222
SNX32 sorting nexin 32 -2.00222
RPS28 ribosomal protein S28 -2.00222
LCAT lecithin-cholesterol acyltransferase -2.00222
ZNF44 zinc finger protein 44 -2.00222
CCDC181 coiled-coil domain containing 181 -2.00222
SGSM1 small G protein signaling modulator 1 -2.00222
ST14 suppression of tumorigenicity 14 (colon carcinoma) -2.00222
AJUBA ajuba LIM protein -2.00222
ANKRD34B ankyrin repeat domain 34B -2.00222
SCAF1 SR-related CTD-associated factor 1 -2.00222
ZNF184 zinc finger protein 184 -2.00222
PXMP2 peroxisomal membrane protein 2, 22kDa -2.00222
TTC8 tetratricopeptide repeat domain 8 -2.00222
SOX15 SRY (sex determining region Y)-box 15 -2.00222
ZNF202 zinc finger protein 202 -2.00222
SCGN secretagogin, EF-hand calcium binding protein -2.00222
KLHL22 kelch-like family member 22 -2.00222
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -2.00222