BRD-A01960364_PD 00735_NPC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

93 genes differentially expressed following the BRD-A01960364_PD 00735_NPC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AFF1 AF4/FMR2 family, member 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
C5 complement component 5
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CXCL8 chemokine (C-X-C motif) ligand 8
DAPK1 death-associated protein kinase 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM171A1 family with sequence similarity 171, member A1
FGB fibrinogen beta chain
FGF13 fibroblast growth factor 13
FGG fibrinogen gamma chain
HBB hemoglobin, beta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
LTF lactotransferrin
LY86 lymphocyte antigen 86
NAP1L1 nucleosome assembly protein 1-like 1
NME4 NME/NM23 nucleoside diphosphate kinase 4
NTS neurotensin
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PDLIM5 PDZ and LIM domain 5
RBMS1 RNA binding motif, single stranded interacting protein 1
RELN reelin
RHOB ras homolog family member B
RPS11 ribosomal protein S11
SFRP1 secreted frizzled-related protein 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SRGN serglycin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TGM2 transglutaminase 2

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AMIGO2 adhesion molecule with Ig-like domain 2
ARL4C ADP-ribosylation factor-like 4C
ATP11B ATPase, class VI, type 11B
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CDC20 cell division cycle 20
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CEP57 centrosomal protein 57kDa
CLEC2B C-type lectin domain family 2, member B
CORO1A coronin, actin binding protein, 1A
CPE carboxypeptidase E
CXCL13 chemokine (C-X-C motif) ligand 13
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
EGLN3 egl-9 family hypoxia-inducible factor 3
EPAS1 endothelial PAS domain protein 1
EREG epiregulin
FBXO21 F-box protein 21
FCGBP Fc fragment of IgG binding protein
FILIP1L filamin A interacting protein 1-like
FXYD6 FXYD domain containing ion transport regulator 6
GRB7 growth factor receptor-bound protein 7
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOMER3 homer scaffolding protein 3
HOPX HOP homeobox
HOXD1 homeobox D1
HTRA1 HtrA serine peptidase 1
IFI27 interferon, alpha-inducible protein 27
KIAA0196 KIAA0196
KLF5 Kruppel-like factor 5 (intestinal)
KLF9 Kruppel-like factor 9
LAPTM4B lysosomal protein transmembrane 4 beta
MB myoglobin
MIR22HG MIR22 host gene
MPO myeloperoxidase
MPZL2 myelin protein zero-like 2
MTFR1 mitochondrial fission regulator 1
NEB nebulin
PAPD7 PAP associated domain containing 7
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PRKCI protein kinase C, iota
RGS16 regulator of G-protein signaling 16
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RTN2 reticulon 2
SDC1 syndecan 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEPP1 selenoprotein P, plasma, 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SNAI2 snail family zinc finger 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPARCL1 SPARC-like 1 (hevin)
SST somatostatin
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMEM176B transmembrane protein 176B
TPD52 tumor protein D52
TUBA4A tubulin, alpha 4a
ZNF395 zinc finger protein 395
Funding