| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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74 genes differentially expressed following the BRD-A07932845_Methiothepin maleate_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ATF3 | activating transcription factor 3 |
| CAST | calpastatin |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CTSZ | cathepsin Z |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| FDPS | farnesyl diphosphate synthase |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| IER5 | immediate early response 5 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IL4R | interleukin 4 receptor |
| INSIG1 | insulin induced gene 1 |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| KRT14 | keratin 14, type I |
| KRT16 | keratin 16, type I |
| KRT6A | keratin 6A, type II |
| KRT6B | keratin 6B, type II |
| LDLR | low density lipoprotein receptor |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MSMO1 | methylsterol monooxygenase 1 |
| NRIP1 | nuclear receptor interacting protein 1 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 |
| RGS5 | regulator of G-protein signaling 5 |
| RPL37A | ribosomal protein L37a |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| S100A2 | S100 calcium binding protein A2 |
| SPRR1A | small proline-rich protein 1A |
| SPRR1B | small proline-rich protein 1B |
| SQLE | squalene epoxidase |
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACPP | acid phosphatase, prostate |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AGR2 | anterior gradient 2 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 |
| CD27 | CD27 molecule |
| COCH | cochlin |
| CRISP3 | cysteine-rich secretory protein 3 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| EGFL6 | EGF-like-domain, multiple 6 |
| EPCAM | epithelial cell adhesion molecule |
| FOSL1 | FOS-like antigen 1 |
| GHR | growth hormone receptor |
| IGHM | immunoglobulin heavy constant mu |
| IGKV4-1 | immunoglobulin kappa variable 4-1 |
| LCN2 | lipocalin 2 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| LIMCH1 | LIM and calponin homology domains 1 |
| LTF | lactotransferrin |
| NKG7 | natural killer cell granule protein 7 |
| OLFM4 | olfactomedin 4 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PLAC8 | placenta-specific 8 |
| PMP22 | peripheral myelin protein 22 |
| POU2AF1 | POU class 2 associating factor 1 |
| RAB31 | RAB31, member RAS oncogene family |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RTN1 | reticulon 1 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SFTPA2 | surfactant protein A2 |
| SFTPB | surfactant protein B |
| SFTPD | surfactant protein D |
| TCL1A | T-cell leukemia/lymphoma 1A |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
