BRD-A09056319_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

27 genes differentially expressed following the BRD-A09056319_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CHEK1 checkpoint kinase 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
EGLN3 egl-9 family hypoxia-inducible factor 3
MFAP5 microfibrillar associated protein 5
MXRA5 matrix-remodelling associated 5
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PTPRE protein tyrosine phosphatase, receptor type, E
S100A10 S100 calcium binding protein A10
SLC38A1 solute carrier family 38, member 1
SPTSSA serine palmitoyltransferase, small subunit A
SULF1 sulfatase 1
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
CHGB chromogranin B
CRISP3 cysteine-rich secretory protein 3
CYBA cytochrome b-245, alpha polypeptide
ENC1 ectodermal-neural cortex 1 (with BTB domain)
HLA-DMB major histocompatibility complex, class II, DM beta
HOMER2 homer scaffolding protein 2
NME4 NME/NM23 nucleoside diphosphate kinase 4
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SORD sorbitol dehydrogenase
STX1A syntaxin 1A (brain)
UGCG UDP-glucose ceramide glucosyltransferase