Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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85 genes differentially expressed following the BRD-A10523515_GSK-429286A_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
AVPI1 | arginine vasopressin-induced 1 |
BCL6 | B-cell CLL/lymphoma 6 |
CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
COLEC12 | collectin sub-family member 12 |
CTSH | cathepsin H |
EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
ETV5 | ets variant 5 |
GRWD1 | glutamate-rich WD repeat containing 1 |
ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
IFI6 | interferon, alpha-inducible protein 6 |
IGFBP5 | insulin-like growth factor binding protein 5 |
IGFBP6 | insulin-like growth factor binding protein 6 |
ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
LEPR | leptin receptor |
LGALS3 | lectin, galactoside-binding, soluble, 3 |
LY6E | lymphocyte antigen 6 complex, locus E |
MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 |
NRIP1 | nuclear receptor interacting protein 1 |
PENK | proenkephalin |
RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
SFRP1 | secreted frizzled-related protein 1 |
SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
SRSF6 | serine/arginine-rich splicing factor 6 |
TCAF1 | TRPM8 channel-associated factor 1 |
TCTA | T-cell leukemia translocation altered |
TIAM1 | T-cell lymphoma invasion and metastasis 1 |
TRAPPC6A | trafficking protein particle complex 6A |
Symbol | Name |
---|---|
ACSL3 | acyl-CoA synthetase long-chain family member 3 |
AK4 | adenylate kinase 4 |
ALB | albumin |
ALDOB | aldolase B, fructose-bisphosphate |
ANK2 | ankyrin 2, neuronal |
AQP1 | aquaporin 1 (Colton blood group) |
ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
CCL2 | chemokine (C-C motif) ligand 2 |
CD58 | CD58 molecule |
COL11A1 | collagen, type XI, alpha 1 |
CRIP2 | cysteine-rich protein 2 |
CST1 | cystatin SN |
CYCS | cytochrome c, somatic |
DEPTOR | DEP domain containing MTOR-interacting protein |
DHCR24 | 24-dehydrocholesterol reductase |
DHCR7 | 7-dehydrocholesterol reductase |
EGF | epidermal growth factor |
FABP1 | fatty acid binding protein 1, liver |
FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
FILIP1L | filamin A interacting protein 1-like |
GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
IER3 | immediate early response 3 |
IGHD | immunoglobulin heavy constant delta |
IGHM | immunoglobulin heavy constant mu |
IGL | immunoglobulin lambda locus |
ISOC1 | isochorismatase domain containing 1 |
KNG1 | kininogen 1 |
KRT20 | keratin 20, type I |
MAGEA3 | melanoma antigen family A3 |
MAL | mal, T-cell differentiation protein |
MMP10 | matrix metallopeptidase 10 |
MSMO1 | methylsterol monooxygenase 1 |
MYB | v-myb avian myeloblastosis viral oncogene homolog |
MYL9 | myosin, light chain 9, regulatory |
NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
PNP | purine nucleoside phosphorylase |
PODXL | podocalyxin-like |
PSAT1 | phosphoserine aminotransferase 1 |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
SPINK1 | serine peptidase inhibitor, Kazal type 1 |
SQLE | squalene epoxidase |
SULF1 | sulfatase 1 |
TACSTD2 | tumor-associated calcium signal transducer 2 |
THBS2 | thrombospondin 2 |
TNIP1 | TNFAIP3 interacting protein 1 |
TXNDC9 | thioredoxin domain containing 9 |
UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |