Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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65 genes differentially expressed following the BRD-A12409803_-666_A375_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
ARG2 | arginase 2 |
ATF3 | activating transcription factor 3 |
CA2 | carbonic anhydrase II |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
CXCR4 | chemokine (C-X-C motif) receptor 4 |
DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 |
EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
FABP4 | fatty acid binding protein 4, adipocyte |
FOLR1 | folate receptor 1 (adult) |
H2AFV | H2A histone family, member V |
HIST1H2BD | histone cluster 1, H2bd |
MEST | mesoderm specific transcript |
ORC1 | origin recognition complex, subunit 1 |
PEG10 | paternally expressed 10 |
PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
PRUNE2 | prune homolog 2 (Drosophila) |
PSPH | phosphoserine phosphatase |
RBP1 | retinol binding protein 1, cellular |
RGCC | regulator of cell cycle |
RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
SCGB1D2 | secretoglobin, family 1D, member 2 |
SFRP4 | secreted frizzled-related protein 4 |
SLC38A2 | solute carrier family 38, member 2 |
SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
TFRC | transferrin receptor |
TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
WASF1 | WAS protein family, member 1 |
ZMAT3 | zinc finger, matrin-type 3 |
Symbol | Name |
---|---|
CDC45 | cell division cycle 45 |
CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
HSPA8 | heat shock 70kDa protein 8 |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
IGFBP7 | insulin-like growth factor binding protein 7 |
INHBA | inhibin, beta A |
ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
JADE2 | jade family PHD finger 2 |
KLF2 | Kruppel-like factor 2 |
KRT5 | keratin 5, type II |
KRT6B | keratin 6B, type II |
LAMC2 | laminin, gamma 2 |
LEF1 | lymphoid enhancer-binding factor 1 |
MOK | MOK protein kinase |
PI3 | peptidase inhibitor 3, skin-derived |
PTBP3 | polypyrimidine tract binding protein 3 |
PTX3 | pentraxin 3, long |
RPS11 | ribosomal protein S11 |
S100A10 | S100 calcium binding protein A10 |
S100A2 | S100 calcium binding protein A2 |
SFN | stratifin |
STX1A | syntaxin 1A (brain) |
TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
TPM1 | tropomyosin 1 (alpha) |
TSPAN8 | tetraspanin 8 |
UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |