| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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155 genes differentially expressed following the BRD-A13122391_16-HYDROXYTRIPTOLIDE_H1299_6.0_h_0.0799999982119_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| A2M | alpha-2-macroglobulin |
| ACKR3 | atypical chemokine receptor 3 |
| AIF1 | allograft inflammatory factor 1 |
| ALOX5 | arachidonate 5-lipoxygenase |
| ANKRD10 | ankyrin repeat domain 10 |
| ANXA3 | annexin A3 |
| ASS1 | argininosuccinate synthase 1 |
| BACE2 | beta-site APP-cleaving enzyme 2 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| BSG | basigin (Ok blood group) |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C3ORF14 | chromosome 3 open reading frame 14 |
| CA12 | carbonic anhydrase XII |
| CD24 | CD24 molecule |
| CD93 | CD93 molecule |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
| CFI | complement factor I |
| COL3A1 | collagen, type III, alpha 1 |
| COL5A1 | collagen, type V, alpha 1 |
| COLEC12 | collectin sub-family member 12 |
| CPE | carboxypeptidase E |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DAPK1 | death-associated protein kinase 1 |
| FGFR3 | fibroblast growth factor receptor 3 |
| FGG | fibrinogen gamma chain |
| GNS | glucosamine (N-acetyl)-6-sulfatase |
| GPNMB | glycoprotein (transmembrane) nmb |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| IL17RB | interleukin 17 receptor B |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MECOM | MDS1 and EVI1 complex locus |
| MRPL13 | mitochondrial ribosomal protein L13 |
| MSMB | microseminoprotein, beta- |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MYCBP | MYC binding protein |
| MYO1B | myosin IB |
| NCF4 | neutrophil cytosolic factor 4, 40kDa |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| OSBPL1A | oxysterol binding protein-like 1A |
| PDZD2 | PDZ domain containing 2 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PXDN | peroxidasin |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RBP1 | retinol binding protein 1, cellular |
| RGS1 | regulator of G-protein signaling 1 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| S100P | S100 calcium binding protein P |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SDC2 | syndecan 2 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SFTPB | surfactant protein B |
| SNX13 | sorting nexin 13 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) |
| TESC | tescalcin |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TNS1 | tensin 1 |
| TPSAB1 | tryptase alpha/beta 1 |
| TPSB2 | tryptase beta 2 (gene/pseudogene) |
| TRIL | TLR4 interactor with leucine-rich repeats |
| TSPAN1 | tetraspanin 1 |
| TSPAN8 | tetraspanin 8 |
| TUBB2B | tubulin, beta 2B class IIb |
| VSIG4 | V-set and immunoglobulin domain containing 4 |
| ZNF423 | zinc finger protein 423 |
| Symbol | Name |
|---|---|
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 |
| ADRB2 | adrenoceptor beta 2, surface |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| CAST | calpastatin |
| CCNF | cyclin F |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CNPY3 | canopy FGF signaling regulator 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DUSP5 | dual specificity phosphatase 5 |
| EGR3 | early growth response 3 |
| EGR4 | early growth response 4 |
| FOSL1 | FOS-like antigen 1 |
| FOXG1 | forkhead box G1 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| H2AFX | H2A histone family, member X |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HOMER1 | homer scaffolding protein 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IER5 | immediate early response 5 |
| IL6R | interleukin 6 receptor |
| JMJD6 | jumonji domain containing 6 |
| KLF10 | Kruppel-like factor 10 |
| KLF9 | Kruppel-like factor 9 |
| LDLR | low density lipoprotein receptor |
| LEFTY1 | left-right determination factor 1 |
| LOC100505650 | uncharacterized LOC100505650 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAGEA12 | melanoma antigen family A12 |
| MAGEA3 | melanoma antigen family A3 |
| MAGEA6 | melanoma antigen family A6 |
| MAP2K3 | mitogen-activated protein kinase kinase 3 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 |
| MAT2A | methionine adenosyltransferase II, alpha |
| MCL1 | myeloid cell leukemia 1 |
| MSH6 | mutS homolog 6 |
| MSX1 | msh homeobox 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NET1 | neuroepithelial cell transforming 1 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PLA2G15 | phospholipase A2, group XV |
| PLAUR | plasminogen activator, urokinase receptor |
| PLK1 | polo-like kinase 1 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit |
| PRKCA | protein kinase C, alpha |
| PROM1 | prominin 1 |
| PURA | purine-rich element binding protein A |
| PVRL3 | poliovirus receptor-related 3 |
| RAP2B | RAP2B, member of RAS oncogene family |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| S100A10 | S100 calcium binding protein A10 |
| S100A6 | S100 calcium binding protein A6 |
| SCGB1D2 | secretoglobin, family 1D, member 2 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC38A2 | solute carrier family 38, member 2 |
| SPATA2 | spermatogenesis associated 2 |
| TAC1 | tachykinin, precursor 1 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TOB2 | transducer of ERBB2, 2 |
| TSC22D2 | TSC22 domain family, member 2 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF131 | zinc finger protein 131 |
| ZNF586 | zinc finger protein 586 |
