Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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88 genes differentially expressed following the BRD-A15297126_FLUOCINONIDE_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABAT | 4-aminobutyrate aminotransferase |
ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase |
CA12 | carbonic anhydrase XII |
CAPN2 | calpain 2, (m/II) large subunit |
CCND2 | cyclin D2 |
CHL1 | cell adhesion molecule L1-like |
COL18A1 | collagen, type XVIII, alpha 1 |
COL5A1 | collagen, type V, alpha 1 |
CPD | carboxypeptidase D |
DDIT4 | DNA-damage-inducible transcript 4 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
EMP1 | epithelial membrane protein 1 |
F13A1 | coagulation factor XIII, A1 polypeptide |
GPI | glucose-6-phosphate isomerase |
GSTA4 | glutathione S-transferase alpha 4 |
HIPK2 | homeodomain interacting protein kinase 2 |
ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
IGFBP4 | insulin-like growth factor binding protein 4 |
IGFBP5 | insulin-like growth factor binding protein 5 |
IRF7 | interferon regulatory factor 7 |
JADE2 | jade family PHD finger 2 |
KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
KDM5D | lysine (K)-specific demethylase 5D |
MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
MAP1B | microtubule-associated protein 1B |
NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
PCOLCE | procollagen C-endopeptidase enhancer |
PGAM1 | phosphoglycerate mutase 1 (brain) |
POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa |
RAB2A | RAB2A, member RAS oncogene family |
SEPP1 | selenoprotein P, plasma, 1 |
SIRT3 | sirtuin 3 |
SYBU | syntabulin (syntaxin-interacting) |
TNC | tenascin C |
TSC22D3 | TSC22 domain family, member 3 |
TUBB2A | tubulin, beta 2A class IIa |
ZCCHC24 | zinc finger, CCHC domain containing 24 |
Symbol | Name |
---|---|
AEBP1 | AE binding protein 1 |
AMIGO2 | adhesion molecule with Ig-like domain 2 |
ANXA4 | annexin A4 |
ATF3 | activating transcription factor 3 |
CASP6 | caspase 6, apoptosis-related cysteine peptidase |
CAV2 | caveolin 2 |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
CHIC2 | cysteine-rich hydrophobic domain 2 |
CRABP2 | cellular retinoic acid binding protein 2 |
CXCL10 | chemokine (C-X-C motif) ligand 10 |
CXCL11 | chemokine (C-X-C motif) ligand 11 |
DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 |
EDN1 | endothelin 1 |
ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
EXT1 | exostosin glycosyltransferase 1 |
FILIP1L | filamin A interacting protein 1-like |
FST | follistatin |
GATA6 | GATA binding protein 6 |
HIST1H1C | histone cluster 1, H1c |
HIST1H2BG | histone cluster 1, H2bg |
HIST1H4C | histone cluster 1, H4c |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
IGL | immunoglobulin lambda locus |
LRMP | lymphoid-restricted membrane protein |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MEIS2 | Meis homeobox 2 |
MSLN | mesothelin |
NXN | nucleoredoxin |
P3H2 | prolyl 3-hydroxylase 2 |
PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
PDZD2 | PDZ domain containing 2 |
PELI1 | pellino E3 ubiquitin protein ligase 1 |
PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
PTPRK | protein tyrosine phosphatase, receptor type, K |
RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
RGS5 | regulator of G-protein signaling 5 |
S100A8 | S100 calcium binding protein A8 |
SCGB2A1 | secretoglobin, family 2A, member 1 |
SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) |
TCTA | T-cell leukemia translocation altered |
THBS1 | thrombospondin 1 |
TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) |
TRD | T cell receptor delta locus |
TRDV3 | T cell receptor delta variable 3 |
VAMP8 | vesicle-associated membrane protein 8 |
XIST | X inactive specific transcript (non-protein coding) |