BRD-A15415227_GW 1929_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-A15415227_GW 1929_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CAT catalase
CCNA1 cyclin A1
CD36 CD36 molecule (thrombospondin receptor)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CSRP1 cysteine and glycine-rich protein 1
CSTA cystatin A (stefin A)
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPCAM epithelial cell adhesion molecule
F2RL1 coagulation factor II (thrombin) receptor-like 1
FCGBP Fc fragment of IgG binding protein
HBB hemoglobin, beta
HIST1H1C histone cluster 1, H1c
HYOU1 hypoxia up-regulated 1
IL1B interleukin 1, beta
IL1R2 interleukin 1 receptor, type II
INHBB inhibin, beta B
JUN jun proto-oncogene
KCNK1 potassium channel, two pore domain subfamily K, member 1
KLF4 Kruppel-like factor 4 (gut)
KLK5 kallikrein-related peptidase 5
KRT6A keratin 6A, type II
LYZ lysozyme
MPZL2 myelin protein zero-like 2
MT1M metallothionein 1M
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDLIM3 PDZ and LIM domain 3
PDZRN3 PDZ domain containing ring finger 3
PLIN2 perilipin 2
PRKCD protein kinase C, delta
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SELENBP1 selenium binding protein 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SOX11 SRY (sex determining region Y)-box 11
ST14 suppression of tumorigenicity 14 (colon carcinoma)
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TUBB2A tubulin, beta 2A class IIa
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CD59 CD59 molecule, complement regulatory protein
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
DDAH1 dimethylarginine dimethylaminohydrolase 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
IGFBP7 insulin-like growth factor binding protein 7
LIPA lipase A, lysosomal acid, cholesterol esterase
LOX lysyl oxidase
MDFIC MyoD family inhibitor domain containing
MEGF9 multiple EGF-like-domains 9
MMP1 matrix metallopeptidase 1
NPR3 natriuretic peptide receptor 3
OSBPL1A oxysterol binding protein-like 1A
PDGFC platelet derived growth factor C
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC39A6 solute carrier family 39 (zinc transporter), member 6
ZMAT3 zinc finger, matrin-type 3
Funding