BRD-A16820783_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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44 genes differentially expressed following the BRD-A16820783_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA4 annexin A4
ARG2 arginase 2
CCL20 chemokine (C-C motif) ligand 20
CD24 CD24 molecule
CFB complement factor B
COMP cartilage oligomeric matrix protein
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
ENO2 enolase 2 (gamma, neuronal)
FLNA filamin A, alpha
IER3 immediate early response 3
IGFBP6 insulin-like growth factor binding protein 6
IVNS1ABP influenza virus NS1A binding protein
JUN jun proto-oncogene
MBP myelin basic protein
MSN moesin
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
RBPMS RNA binding protein with multiple splicing
RCAN1 regulator of calcineurin 1
RGCC regulator of cell cycle
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
STMN2 stathmin 2
TFPI2 tissue factor pathway inhibitor 2
TKTL1 transketolase-like 1
TPP1 tripeptidyl peptidase I
VSNL1 visinin-like 1

decreased expression

Symbol Name
ATF5 activating transcription factor 5
C14ORF2 chromosome 14 open reading frame 2
CANT1 calcium activated nucleotidase 1
DCN decorin
INSIG1 insulin induced gene 1
ITGB1BP1 integrin beta 1 binding protein 1
MICU2 mitochondrial calcium uptake 2
MSLN mesothelin
ODC1 ornithine decarboxylase 1
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
RAD23B RAD23 homolog B (S. cerevisiae)
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
TBX2 T-box 2
TUBB6 tubulin, beta 6 class V
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)