BRD-A18328003_GDC-0980_BT20_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

70 genes differentially expressed following the BRD-A18328003_GDC-0980_BT20_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHSG alpha-2-HS-glycoprotein
ALB albumin
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ANG angiogenin, ribonuclease, RNase A family, 5
ANKRD36B ankyrin repeat domain 36B
APOA2 apolipoprotein A-II
APOB apolipoprotein B
APOC2 apolipoprotein C-II
APOM apolipoprotein M
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CFB complement factor B
COL11A1 collagen, type XI, alpha 1
COLEC12 collectin sub-family member 12
CTGF connective tissue growth factor
CXADR coxsackie virus and adenovirus receptor
DMD dystrophin
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
FST follistatin
GPNMB glycoprotein (transmembrane) nmb
HIST1H1C histone cluster 1, H1c
HIST1H2BD histone cluster 1, H2bd
LEF1 lymphoid enhancer-binding factor 1
LPXN leupaxin
METTL7A methyltransferase like 7A
MT1E metallothionein 1E
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNASE4 ribonuclease, RNase A family, 4
SDC2 syndecan 2
SGK1 serum/glucocorticoid regulated kinase 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
STK38L serine/threonine kinase 38 like
TCF4 transcription factor 4
TF transferrin
TGFBI transforming growth factor, beta-induced, 68kDa
TIAM1 T-cell lymphoma invasion and metastasis 1
TM7SF2 transmembrane 7 superfamily member 2
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ALDOA aldolase A, fructose-bisphosphate
ANXA3 annexin A3
ANXA6 annexin A6
CAV2 caveolin 2
CD24 CD24 molecule
CTSE cathepsin E
CXCL13 chemokine (C-X-C motif) ligand 13
ENO1 enolase 1, (alpha)
FLRT3 fibronectin leucine rich transmembrane protein 3
GPI glucose-6-phosphate isomerase
GPRC5A G protein-coupled receptor, class C, group 5, member A
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
LIMCH1 LIM and calponin homology domains 1
MALL mal, T-cell differentiation protein-like
MMP12 matrix metallopeptidase 12
MMP7 matrix metallopeptidase 7
PCNA proliferating cell nuclear antigen
PNP purine nucleoside phosphorylase
PRDX2 peroxiredoxin 2
RDX radixin
S100P S100 calcium binding protein P
SFN stratifin
SLPI secretory leukocyte peptidase inhibitor
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
UXS1 UDP-glucuronate decarboxylase 1
Funding