BRD-A18328003_GDC-0980_HS578T_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-A18328003_GDC-0980_HS578T_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMDEC1 ADAM-like, decysin 1
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADIRF adipogenesis regulatory factor
AKAP9 A kinase (PRKA) anchor protein 9
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ARID5B AT rich interactive domain 5B (MRF1-like)
ATP9A ATPase, class II, type 9A
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD59 CD59 molecule, complement regulatory protein
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CST3 cystatin C
CTGF connective tissue growth factor
DEPTOR DEP domain containing MTOR-interacting protein
DUSP1 dual specificity phosphatase 1
EFNA1 ephrin-A1
EMP1 epithelial membrane protein 1
ETV1 ets variant 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FBN1 fibrillin 1
FBN2 fibrillin 2
FGF13 fibroblast growth factor 13
FOXO4 forkhead box O4
GATA2 GATA binding protein 2
GLRX glutaredoxin (thioltransferase)
GLUD1 glutamate dehydrogenase 1
GLUL glutamate-ammonia ligase
GREM1 gremlin 1, DAN family BMP antagonist
ITGAV integrin, alpha V
KIAA0125 KIAA0125
KLF9 Kruppel-like factor 9
MAN1A1 mannosidase, alpha, class 1A, member 1
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MXRA7 matrix-remodelling associated 7
MYB v-myb avian myeloblastosis viral oncogene homolog
MYO5C myosin VC
MYO6 myosin VI
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
POSTN periostin, osteoblast specific factor
PSD3 pleckstrin and Sec7 domain containing 3
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEPP1 selenoprotein P, plasma, 1
SH3YL1 SH3 and SYLF domain containing 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STK26 serine/threonine protein kinase 26
SULF1 sulfatase 1
SYNGR3 synaptogyrin 3
TM4SF1 transmembrane 4 L six family member 1
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TSC22D1 TSC22 domain family, member 1
VCAN versican
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
AK4 adenylate kinase 4
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BRD4 bromodomain containing 4
CCND2 cyclin D2
CD24 CD24 molecule
CLTB clathrin, light chain B
CXCL12 chemokine (C-X-C motif) ligand 12
DDIT4 DNA-damage-inducible transcript 4
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EIF5A eukaryotic translation initiation factor 5A
FABP7 fatty acid binding protein 7, brain
FOXM1 forkhead box M1
GGCT gamma-glutamylcyclotransferase
GINS1 GINS complex subunit 1 (Psf1 homolog)
HOXB7 homeobox B7
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SNAP25 synaptosomal-associated protein, 25kDa
SPINK1 serine peptidase inhibitor, Kazal type 1
SRSF6 serine/arginine-rich splicing factor 6
TDO2 tryptophan 2,3-dioxygenase
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
ZDHHC6 zinc finger, DHHC-type containing 6
ZFP36L1 ZFP36 ring finger protein-like 1
ZWINT ZW10 interacting kinetochore protein
Funding