BRD-A18328003_GDC-0980_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-A18328003_GDC-0980_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CDC25B cell division cycle 25B
CEMIP cell migration inducing protein, hyaluronan binding
COMP cartilage oligomeric matrix protein
CPE carboxypeptidase E
CRISP3 cysteine-rich secretory protein 3
CST1 cystatin SN
CST6 cystatin E/M
EMX2 empty spiracles homeobox 2
FHL1 four and a half LIM domains 1
FZD7 frizzled class receptor 7
GPX3 glutathione peroxidase 3
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
MAP7 microtubule-associated protein 7
MEF2C myocyte enhancer factor 2C
MFAP5 microfibrillar associated protein 5
NT5E 5'-nucleotidase, ecto (CD73)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OLFM1 olfactomedin 1
PEG3 paternally expressed 3
PPAP2B phosphatidic acid phosphatase type 2B
PTN pleiotrophin
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
QPCT glutaminyl-peptide cyclotransferase
SALL1 spalt-like transcription factor 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SOX4 SRY (sex determining region Y)-box 4
SYT1 synaptotagmin I
TIMP3 TIMP metallopeptidase inhibitor 3
TLR4 toll-like receptor 4
TNC tenascin C
VCAN versican
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
ZBTB20 zinc finger and BTB domain containing 20
ZNF292 zinc finger protein 292

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
CCND1 cyclin D1
CD36 CD36 molecule (thrombospondin receptor)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
FABP5 fatty acid binding protein 5 (psoriasis-associated)
IL32 interleukin 32
ITGB1BP1 integrin beta 1 binding protein 1
KLHL9 kelch-like family member 9
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
MAGEA1 melanoma antigen family A1
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NR2F6 nuclear receptor subfamily 2, group F, member 6
PLAC8 placenta-specific 8
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRKCH protein kinase C, eta
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100P S100 calcium binding protein P
SKP1 S-phase kinase-associated protein 1
SRGN serglycin
Funding