Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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128 genes differentially expressed following the BRD-A18328003_GDC-0980_MCF7_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADGRG6 | adhesion G protein-coupled receptor G6 |
AMDHD2 | amidohydrolase domain containing 2 |
ARG2 | arginase 2 |
ARHGAP29 | Rho GTPase activating protein 29 |
BST2 | bone marrow stromal cell antigen 2 |
C10ORF10 | chromosome 10 open reading frame 10 |
C8ORF4 | chromosome 8 open reading frame 4 |
CCNG2 | cyclin G2 |
CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
CDK19 | cyclin-dependent kinase 19 |
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
EDNRB | endothelin receptor type B |
ELOVL2 | ELOVL fatty acid elongase 2 |
FABP7 | fatty acid binding protein 7, brain |
FOXO3 | forkhead box O3 |
FXYD2 | FXYD domain containing ion transport regulator 2 |
FZD6 | frizzled class receptor 6 |
GDF15 | growth differentiation factor 15 |
GNS | glucosamine (N-acetyl)-6-sulfatase |
H3F3B | H3 histone, family 3B (H3.3B) |
HBP1 | HMG-box transcription factor 1 |
HIST1H2BG | histone cluster 1, H2bg |
HLA-B | major histocompatibility complex, class I, B |
HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
HLA-DRA | major histocompatibility complex, class II, DR alpha |
HLA-F | major histocompatibility complex, class I, F |
HLA-G | major histocompatibility complex, class I, G |
HMOX1 | heme oxygenase 1 |
HOXC6 | homeobox C6 |
IGL | immunoglobulin lambda locus |
INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
JCHAIN | joining chain of multimeric IgA and IgM |
KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
KDM3A | lysine (K)-specific demethylase 3A |
MAL | mal, T-cell differentiation protein |
MGP | matrix Gla protein |
MSMB | microseminoprotein, beta- |
MX1 | MX dynamin-like GTPase 1 |
MX2 | MX dynamin-like GTPase 2 |
MXI1 | MAX interactor 1, dimerization protein |
NAP1L1 | nucleosome assembly protein 1-like 1 |
NPY1R | neuropeptide Y receptor Y1 |
NRIP1 | nuclear receptor interacting protein 1 |
PCM1 | pericentriolar material 1 |
PDGFRL | platelet-derived growth factor receptor-like |
PLD1 | phospholipase D1, phosphatidylcholine-specific |
POSTN | periostin, osteoblast specific factor |
PROM1 | prominin 1 |
RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
SASH1 | SAM and SH3 domain containing 1 |
SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 |
SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
SMYD3 | SET and MYND domain containing 3 |
SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
SNX10 | sorting nexin 10 |
SOX4 | SRY (sex determining region Y)-box 4 |
SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
TARBP1 | TAR (HIV-1) RNA binding protein 1 |
TBX3 | T-box 3 |
TM4SF1 | transmembrane 4 L six family member 1 |
TUSC3 | tumor suppressor candidate 3 |
UGCG | UDP-glucose ceramide glucosyltransferase |
WWTR1 | WW domain containing transcription regulator 1 |
XIST | X inactive specific transcript (non-protein coding) |
Symbol | Name |
---|---|
ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide |
ADO | 2-aminoethanethiol (cysteamine) dioxygenase |
ADRB2 | adrenoceptor beta 2, surface |
ANXA1 | annexin A1 |
AREG | amphiregulin |
AUTS2 | autism susceptibility candidate 2 |
BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
C14ORF132 | chromosome 14 open reading frame 132 |
C6ORF62 | chromosome 6 open reading frame 62 |
CCND1 | cyclin D1 |
CD24 | CD24 molecule |
CDC20 | cell division cycle 20 |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CKB | creatine kinase, brain |
CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
DBN1 | drebrin 1 |
DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
DUSP2 | dual specificity phosphatase 2 |
EGR1 | early growth response 1 |
EIF1B | eukaryotic translation initiation factor 1B |
EIF5 | eukaryotic translation initiation factor 5 |
EIF5A | eukaryotic translation initiation factor 5A |
FAM129A | family with sequence similarity 129, member A |
FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
FSCN1 | fascin actin-bundling protein 1 |
G0S2 | G0/G1 switch 2 |
GAL | galanin/GMAP prepropeptide |
GLUL | glutamate-ammonia ligase |
GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
GPX1 | glutathione peroxidase 1 |
HSPA1A | heat shock 70kDa protein 1A |
HTRA1 | HtrA serine peptidase 1 |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
IFRD2 | interferon-related developmental regulator 2 |
JMJD6 | jumonji domain containing 6 |
LPL | lipoprotein lipase |
LTF | lactotransferrin |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MAT2A | methionine adenosyltransferase II, alpha |
MFAP5 | microfibrillar associated protein 5 |
MMP9 | matrix metallopeptidase 9 |
ORM1 | orosomucoid 1 |
PEA15 | phosphoprotein enriched in astrocytes 15 |
PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 |
PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) |
RGCC | regulator of cell cycle |
ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
S100A8 | S100 calcium binding protein A8 |
SCGB2A1 | secretoglobin, family 2A, member 1 |
SIRT3 | sirtuin 3 |
SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
SLPI | secretory leukocyte peptidase inhibitor |
STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |