BRD-A18328003_GDC-0980_MDAMB231_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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53 genes differentially expressed following the BRD-A18328003_GDC-0980_MDAMB231_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANOS1 anosmin 1
APOE apolipoprotein E
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL6 B-cell CLL/lymphoma 6
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CLDN3 claudin 3
COL4A1 collagen, type IV, alpha 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRABP1 cellular retinoic acid binding protein 1
DOCK4 dedicator of cytokinesis 4
DPYSL3 dihydropyrimidinase-like 3
ETV1 ets variant 1
FOLR1 folate receptor 1 (adult)
GJA1 gap junction protein, alpha 1, 43kDa
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LEPR leptin receptor
LIMCH1 LIM and calponin homology domains 1
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MMP2 matrix metallopeptidase 2
MNDA myeloid cell nuclear differentiation antigen
NTS neurotensin
NUPR1 nuclear protein, transcriptional regulator, 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PIEZO2 piezo-type mechanosensitive ion channel component 2
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLSCR4 phospholipid scramblase 4
SESN1 sestrin 1
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC38A2 solute carrier family 38, member 2
SOD2 superoxide dismutase 2, mitochondrial
SRGN serglycin
TACSTD2 tumor-associated calcium signal transducer 2
TCF4 transcription factor 4
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TFF3 trefoil factor 3 (intestinal)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
VCAN versican
VNN1 vanin 1
WFS1 Wolfram syndrome 1 (wolframin)

decreased expression

Symbol Name
BMI1 BMI1 proto-oncogene, polycomb ring finger
CAV1 caveolin 1, caveolae protein, 22kDa
CD320 CD320 molecule
FGFBP1 fibroblast growth factor binding protein 1
HMGN3 high mobility group nucleosomal binding domain 3
HOXA10 homeobox A10
IFI44L interferon-induced protein 44-like
MAL mal, T-cell differentiation protein
NRIP1 nuclear receptor interacting protein 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SPRR1A small proline-rich protein 1A
TKTL1 transketolase-like 1