| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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251 genes differentially expressed following the BRD-A19500257_geldanamycin_BT20_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABHD4 | abhydrolase domain containing 4 |
| ACKR3 | atypical chemokine receptor 3 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 |
| AFF1 | AF4/FMR2 family, member 1 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| ALCAM | activated leukocyte cell adhesion molecule |
| APOD | apolipoprotein D |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| AURKA | aurora kinase A |
| B3GNT1 | |
| BAG3 | BCL2-associated athanogene 3 |
| BAX | BCL2-associated X protein |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C1QA | complement component 1, q subcomponent, A chain |
| C1QB | complement component 1, q subcomponent, B chain |
| CA12 | carbonic anhydrase XII |
| CALU | calumenin |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CCDC28A | coiled-coil domain containing 28A |
| CD1A | CD1a molecule |
| CDK19 | cyclin-dependent kinase 19 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| COL1A2 | collagen, type I, alpha 2 |
| COL3A1 | collagen, type III, alpha 1 |
| COL6A3 | collagen, type VI, alpha 3 |
| COPA | coatomer protein complex, subunit alpha |
| CPE | carboxypeptidase E |
| CRYAB | crystallin, alpha B |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component |
| CTSK | cathepsin K |
| CXCL13 | chemokine (C-X-C motif) ligand 13 |
| DCN | decorin |
| DEFB1 | defensin, beta 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GLUL | glutamate-ammonia ligase |
| GPNMB | glycoprotein (transmembrane) nmb |
| HIST1H2BK | histone cluster 1, H2bk |
| HMGB2 | high mobility group box 2 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPB8 | heat shock 22kDa protein 8 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
| HSPE1 | heat shock 10kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| INPP1 | inositol polyphosphate-1-phosphatase |
| INSR | insulin receptor |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat |
| JAK1 | Janus kinase 1 |
| JMJD6 | jumonji domain containing 6 |
| KDM3A | lysine (K)-specific demethylase 3A |
| KIF3B | kinesin family member 3B |
| KLHDC10 | kelch domain containing 10 |
| KRT19 | keratin 19, type I |
| LAMB1 | laminin, beta 1 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LY96 | lymphocyte antigen 96 |
| MAGED2 | melanoma antigen family D2 |
| MAOA | monoamine oxidase A |
| MARCH8 | membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase |
| MB | myoglobin |
| MEIS2 | Meis homeobox 2 |
| MFAP5 | microfibrillar associated protein 5 |
| MME | membrane metallo-endopeptidase |
| MOXD1 | monooxygenase, DBH-like 1 |
| MSMB | microseminoprotein, beta- |
| NEFL | neurofilament, light polypeptide |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
| NPTX2 | neuronal pentraxin II |
| OLFML3 | olfactomedin-like 3 |
| OXTR | oxytocin receptor |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I |
| PCDH9 | protocadherin 9 |
| PEG3 | paternally expressed 3 |
| PIP | prolactin-induced protein |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 |
| POPDC3 | popeye domain containing 3 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PTN | pleiotrophin |
| PTX3 | pentraxin 3, long |
| RANBP2 | RAN binding protein 2 |
| RIOK3 | RIO kinase 3 |
| RND3 | Rho family GTPase 3 |
| SCG2 | secretogranin II |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) |
| SNX3 | sorting nexin 3 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STK17B | serine/threonine kinase 17b |
| STOM | stomatin |
| TARP | TCR gamma alternate reading frame protein |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMEM45A | transmembrane protein 45A |
| TMEM47 | transmembrane protein 47 |
| TPBG | trophoblast glycoprotein |
| TSC22D3 | TSC22 domain family, member 3 |
| TWF1 | twinfilin actin binding protein 1 |
| TWIST1 | twist family bHLH transcription factor 1 |
| TXNIP | thioredoxin interacting protein |
| UPK1B | uroplakin 1B |
| ZC3H11A | zinc finger CCCH-type containing 11A |
| ZNF304 | zinc finger protein 304 |
| ZNF331 | zinc finger protein 331 |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| ABLIM1 | actin binding LIM protein 1 |
| ACD | adrenocortical dysplasia homolog (mouse) |
| ADRB2 | adrenoceptor beta 2, surface |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANKRD10 | ankyrin repeat domain 10 |
| ANXA3 | annexin A3 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ATP11B | ATPase, class VI, type 11B |
| ATP5S | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) |
| CAB39 | calcium binding protein 39 |
| CALML5 | calmodulin-like 5 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CCNE2 | cyclin E2 |
| CD24 | CD24 molecule |
| CDC25A | cell division cycle 25A |
| CDC45 | cell division cycle 45 |
| CDK4 | cyclin-dependent kinase 4 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CLIC3 | chloride intracellular channel 3 |
| CRIP2 | cysteine-rich protein 2 |
| CRLF1 | cytokine receptor-like factor 1 |
| CSRP1 | cysteine and glycine-rich protein 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 |
| DERA | deoxyribose-phosphate aldolase (putative) |
| DHFR | dihydrofolate reductase |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DLX2 | distal-less homeobox 2 |
| DMD | dystrophin |
| EIF5 | eukaryotic translation initiation factor 5 |
| EREG | epiregulin |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FKBP11 | FK506 binding protein 11, 19 kDa |
| FOSL1 | FOS-like antigen 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HLF | hepatic leukemia factor |
| HN1 | hematological and neurological expressed 1 |
| HOPX | HOP homeobox |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER3 | immediate early response 3 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL17RB | interleukin 17 receptor B |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
| ITGA6 | integrin, alpha 6 |
| JAG1 | jagged 1 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| JUN | jun proto-oncogene |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KIAA0485 | uncharacterized LOC57235 |
| KIF20A | kinesin family member 20A |
| KLF6 | Kruppel-like factor 6 |
| KRT6B | keratin 6B, type II |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LIMCH1 | LIM and calponin homology domains 1 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LMNA | lamin A/C |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor |
| MACF1 | microtubule-actin crosslinking factor 1 |
| MARCKSL1 | MARCKS-like 1 |
| MCM3 | minichromosome maintenance complex component 3 |
| MPZL2 | myelin protein zero-like 2 |
| MSH6 | mutS homolog 6 |
| NFIB | nuclear factor I/B |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| PALMD | palmdelphin |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHYH | phytanoyl-CoA 2-hydroxylase |
| PITX1 | paired-like homeodomain 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLN | phospholamban |
| PNP | purine nucleoside phosphorylase |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PRKCD | protein kinase C, delta |
| PRSS2 | protease, serine, 2 (trypsin 2) |
| PRSS3 | protease, serine, 3 |
| RBPMS | RNA binding protein with multiple splicing |
| RPL37A | ribosomal protein L37a |
| RPL38 | ribosomal protein L38 |
| RPS11 | ribosomal protein S11 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SET | SET nuclear proto-oncogene |
| SFN | stratifin |
| SFRP4 | secreted frizzled-related protein 4 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SPP1 | secreted phosphoprotein 1 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TAGLN2 | transgelin 2 |
| TKTL1 | transketolase-like 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TPM1 | tropomyosin 1 (alpha) |
| TRIB3 | tribbles pseudokinase 3 |
| TYRP1 | tyrosinase-related protein 1 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZFPM2 | zinc finger protein, FOG family member 2 |
