BRD-A19500257_geldanamycin_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

895 genes differentially expressed following the BRD-A19500257_geldanamycin_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ABAT 4-aminobutyrate aminotransferase
ABHD4 abhydrolase domain containing 4
ACBD3 acyl-CoA binding domain containing 3
ACLY ATP citrate lyase
ACOT7 acyl-CoA thioesterase 7
ACSF2 acyl-CoA synthetase family member 2
ACSL3 acyl-CoA synthetase long-chain family member 3
ADA adenosine deaminase
ADCY9 adenylate cyclase 9
AGR2 anterior gradient 2
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AKAP12 A kinase (PRKA) anchor protein 12
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDOC aldolase C, fructose-bisphosphate
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMDHD2 amidohydrolase domain containing 2
ANG angiogenin, ribonuclease, RNase A family, 5
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ANXA6 annexin A6
AOX1 aldehyde oxidase 1
APOD apolipoprotein D
AQP3 aquaporin 3 (Gill blood group)
ARCN1 archain 1
ARF1 ADP-ribosylation factor 1
ARF4 ADP-ribosylation factor 4
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARHGAP29 Rho GTPase activating protein 29
ARID4B AT rich interactive domain 4B (RBP1-like)
ARL1 ADP-ribosylation factor-like 1
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ARMCX3 armadillo repeat containing, X-linked 3
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ASMTL acetylserotonin O-methyltransferase-like
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
BAD BCL2-associated agonist of cell death
BAG3 BCL2-associated athanogene 3
BASP1 brain abundant, membrane attached signal protein 1
BET1 Bet1 golgi vesicular membrane trafficking protein
BEX4 brain expressed, X-linked 4
BIN1 bridging integrator 1
BIRC2 baculoviral IAP repeat containing 2
BLNK B-cell linker
BLVRA biliverdin reductase A
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C10ORF10 chromosome 10 open reading frame 10
C1S complement component 1, s subcomponent
C3 complement component 3
CA2 carbonic anhydrase II
CACYBP calcyclin binding protein
CALCOCO2 calcium binding and coiled-coil domain 2
CALD1 caldesmon 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALR calreticulin
CALU calumenin
CANX calnexin
CAPG capping protein (actin filament), gelsolin-like
CAPN6 calpain 6
CARS cysteinyl-tRNA synthetase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CAST calpastatin
CBS cystathionine-beta-synthase
CCND3 cyclin D3
CCNG2 cyclin G2
CCPG1 cell cycle progression 1
CD14 CD14 molecule
CD163 CD163 molecule
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD81 CD81 molecule
CD99 CD99 molecule
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK19 cyclin-dependent kinase 19
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CES1 carboxylesterase 1
CETN2 centrin, EF-hand protein, 2
CFD complement factor D (adipsin)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHPT1 choline phosphotransferase 1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CIB1 calcium and integrin binding 1 (calmyrin)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CKAP4 cytoskeleton-associated protein 4
CLDN10 claudin 10
CLIC4 chloride intracellular channel 4
CLIP1 CAP-GLY domain containing linker protein 1
CLU clusterin
COBLL1 cordon-bleu WH2 repeat protein-like 1
COCH cochlin
COL15A1 collagen, type XV, alpha 1
COL1A1 collagen, type I, alpha 1
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
COPB1 coatomer protein complex, subunit beta 1
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
CP ceruloplasmin (ferroxidase)
CPM carboxypeptidase M
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CREB3L2 cAMP responsive element binding protein 3-like 2
CRELD2 cysteine-rich with EGF-like domains 2
CRIP1 cysteine-rich protein 1 (intestinal)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRYZ crystallin, zeta (quinone reductase)
CSRP2 cysteine and glycine-rich protein 2
CST3 cystatin C
CTBS chitobiase, di-N-acetyl-
CTR9 CTR9, Paf1/RNA polymerase II complex component
CTSH cathepsin H
CTSV cathepsin V
CTSZ cathepsin Z
CXCL10 chemokine (C-X-C motif) ligand 10
CYB561 cytochrome b561
CYB5R1 cytochrome b5 reductase 1
CYBB cytochrome b-245, beta polypeptide
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYTIP cytohesin 1 interacting protein
DAXX death-domain associated protein
DCN decorin
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
DERL2 derlin 2
DES desmin
DHDDS dehydrodolichyl diphosphate synthase
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOCK4 dedicator of cytokinesis 4
DPYSL2 dihydropyrimidinase-like 2
DSP desmoplakin
DSTN destrin (actin depolymerizing factor)
ECHDC3 enoyl CoA hydratase domain containing 3
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGFL6 EGF-like-domain, multiple 6
EGFR epidermal growth factor receptor
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EIF5A eukaryotic translation initiation factor 5A
ELANE elastase, neutrophil expressed
ELL2 elongation factor, RNA polymerase II, 2
ELOVL5 ELOVL fatty acid elongase 5
EPRS glutamyl-prolyl-tRNA synthetase
ERAP1 endoplasmic reticulum aminopeptidase 1
ERP44 endoplasmic reticulum protein 44
ETNPPL ethanolamine-phosphate phospho-lyase
EVI2A ecotropic viral integration site 2A
EVI2B ecotropic viral integration site 2B
EXPH5 exophilin 5
FADS1 fatty acid desaturase 1
FADS3 fatty acid desaturase 3
FAM114A1 family with sequence similarity 114, member A1
FAM117A family with sequence similarity 117, member A
FAM129A family with sequence similarity 129, member A
FAM13A family with sequence similarity 13, member A
FBP1 fructose-1,6-bisphosphatase 1
FICD FIC domain containing
FKBP11 FK506 binding protein 11, 19 kDa
FKBP14 FK506 binding protein 14, 22 kDa
FKBP1B FK506 binding protein 1B, 12.6 kDa
FKBP2 FK506 binding protein 2, 13kDa
FLNA filamin A, alpha
FN1 fibronectin 1
FNDC3A fibronectin type III domain containing 3A
FOXO4 forkhead box O4
FXR1 fragile X mental retardation, autosomal homolog 1
FYN FYN proto-oncogene, Src family tyrosine kinase
FZD2 frizzled class receptor 2
GABARAPL1 GABA(A) receptor-associated protein like 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GADD45B growth arrest and DNA-damage-inducible, beta
GARS glycyl-tRNA synthetase
GATA3 GATA binding protein 3
GCLM glutamate-cysteine ligase, modifier subunit
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GJA1 gap junction protein, alpha 1, 43kDa
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNB5 guanine nucleotide binding protein (G protein), beta 5
GNS glucosamine (N-acetyl)-6-sulfatase
GOLGB1 golgin B1
GOLPH3L golgi phosphoprotein 3-like
GOLT1B golgi transport 1B
GORASP2 golgi reassembly stacking protein 2, 55kDa
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GSTA1 glutathione S-transferase alpha 1
GSTO1 glutathione S-transferase omega 1
GSTP1 glutathione S-transferase pi 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
GUSBP11 glucuronidase, beta pseudogene 11
H1F0 H1 histone family, member 0
HDLBP high density lipoprotein binding protein
HEBP1 heme binding protein 1
HECA headcase homolog (Drosophila)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H1C histone cluster 1, H1c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HNMT histamine N-methyltransferase
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HOPX HOP homeobox
HOXB2 homeobox B2
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA4L heat shock 70kDa protein 4-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
HYOU1 hypoxia up-regulated 1
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IDI1 isopentenyl-diphosphate delta isomerase 1
IDS iduronate 2-sulfatase
IER5 immediate early response 5
IFI27 interferon, alpha-inducible protein 27
IFI30 interferon, gamma-inducible protein 30
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM3 interferon induced transmembrane protein 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
IGHA1 immunoglobulin heavy constant alpha 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV3-20 immunoglobulin kappa variable 3-20
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IGLV1-40 immunoglobulin lambda variable 1-40
IGLV2-23 immunoglobulin lambda variable 2-23
IGLV3-19 immunoglobulin lambda variable 3-19
IL6ST interleukin 6 signal transducer
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
ISLR immunoglobulin superfamily containing leucine-rich repeat
JCHAIN joining chain of multimeric IgA and IgM
JMJD6 jumonji domain containing 6
KCTD5 potassium channel tetramerization domain containing 5
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KDM5A lysine (K)-specific demethylase 5A
KDM5D lysine (K)-specific demethylase 5D
KRT13 keratin 13, type I
KRT18 keratin 18, type I
KRT19 keratin 19, type I
L1CAM L1 cell adhesion molecule
LAMP2 lysosomal-associated membrane protein 2
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
LAPTM5 lysosomal protein transmembrane 5
LCN2 lipocalin 2
LGALS1 lectin, galactoside-binding, soluble, 1
LGMN legumain
LINC00094 long intergenic non-protein coding RNA 94
LIPA lipase A, lysosomal acid, cholesterol esterase
LITAF lipopolysaccharide-induced TNF factor
LPCAT1 lysophosphatidylcholine acyltransferase 1
LPIN1 lipin 1
LRRC59 leucine rich repeat containing 59
LTF lactotransferrin
LXN latexin
LYZ lysozyme
LZTFL1 leucine zipper transcription factor-like 1
MAGED1 melanoma antigen family D1
MAGT1 magnesium transporter 1
MAN2A1 mannosidase, alpha, class 2A, member 1
MANF mesencephalic astrocyte-derived neurotrophic factor
MAOA monoamine oxidase A
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MARS methionyl-tRNA synthetase
MB myoglobin
MBNL2 muscleblind-like splicing regulator 2
MCOLN1 mucolipin 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
METRN meteorin, glial cell differentiation regulator
MFAP5 microfibrillar associated protein 5
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MICB MHC class I polypeptide-related sequence B
MIS12 MIS12 kinetochore complex component
MKNK2 MAP kinase interacting serine/threonine kinase 2
MKRN1 makorin ring finger protein 1
MLF1 myeloid leukemia factor 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MORF4L2 mortality factor 4 like 2
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MSLN mesothelin
MSMB microseminoprotein, beta-
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MUC5B mucin 5B, oligomeric mucus/gel-forming
MX1 MX dynamin-like GTPase 1
MXI1 MAX interactor 1, dimerization protein
MXRA5 matrix-remodelling associated 5
MXRA7 matrix-remodelling associated 7
MYDGF myeloid-derived growth factor
MZB1 marginal zone B and B1 cell-specific protein
NANS N-acetylneuraminic acid synthase
NCOA3 nuclear receptor coactivator 3
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEB nebulin
NEBL nebulette
NEU1 sialidase 1 (lysosomal sialidase)
NFE2L1 nuclear factor, erythroid 2-like 1
NKX3-1 NK3 homeobox 1
NOSIP nitric oxide synthase interacting protein
NRIP1 nuclear receptor interacting protein 1
NT5DC2 5'-nucleotidase domain containing 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUCB2 nucleobindin 2
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
NUPR1 nuclear protein, transcriptional regulator, 1
NXT2 nuclear transport factor 2-like export factor 2
OAT ornithine aminotransferase
OLFM4 olfactomedin 4
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OPTN optineurin
OSBPL8 oxysterol binding protein-like 8
OSR2 odd-skipped related transciption factor 2
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
P4HB prolyl 4-hydroxylase, beta polypeptide
PALLD palladin, cytoskeletal associated protein
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PARK7 parkinson protein 7
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCP4 Purkinje cell protein 4
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PCSK5 proprotein convertase subtilisin/kexin type 5
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PDIA3 protein disulfide isomerase family A, member 3
PDIA4 protein disulfide isomerase family A, member 4
PDIA5 protein disulfide isomerase family A, member 5
PDIA6 protein disulfide isomerase family A, member 6
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PEG3 paternally expressed 3
PFN2 profilin 2
PGC progastricsin (pepsinogen C)
PGM3 phosphoglucomutase 3
PHGDH phosphoglycerate dehydrogenase
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIR pirin (iron-binding nuclear protein)
PLA2G15 phospholipase A2, group XV
PLAC8 placenta-specific 8
PLD3 phospholipase D family, member 3
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PMP22 peripheral myelin protein 22
PON3 paraoxonase 3
POU2AF1 POU class 2 associating factor 1
PPAP2B phosphatidic acid phosphatase type 2B
PPIB peptidylprolyl isomerase B (cyclophilin B)
PRDX1 peroxiredoxin 1
PRDX4 peroxiredoxin 4
PRKCD protein kinase C, delta
PRSS8 protease, serine, 8
PRTN3 proteinase 3
PSAP prosaposin
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB29 RAB29, member RAS oncogene family
RABAC1 Rab acceptor 1 (prenylated)
RAD9A RAD9 homolog A (S. pombe)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBKS ribokinase
RBM47 RNA binding motif protein 47
RGS1 regulator of G-protein signaling 1
RGS10 regulator of G-protein signaling 10
RHOBTB3 Rho-related BTB domain containing 3
RIOK3 RIO kinase 3
RNASE4 ribonuclease, RNase A family, 4
ROGDI rogdi homolog (Drosophila)
RPL27A ribosomal protein L27a
RPN2 ribophorin II
RPS4Y1 ribosomal protein S4, Y-linked 1
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RRBP1 ribosome binding protein 1
RTN3 reticulon 3
S100A11 S100 calcium binding protein A11
S100A14 S100 calcium binding protein A14
S100P S100 calcium binding protein P
SAR1B secretion associated, Ras related GTPase 1B
SARAF store-operated calcium entry-associated regulatory factor
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCGB2A1 secretoglobin, family 2A, member 1
SCPEP1 serine carboxypeptidase 1
SDC2 syndecan 2
SDF2L1 stromal cell-derived factor 2-like 1
SEC13 SEC13 homolog (S. cerevisiae)
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SEC23B Sec23 homolog B (S. cerevisiae)
SEC24A SEC24 family member A
SEC24D SEC24 family member D
SEC31A SEC31 homolog A (S. cerevisiae)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEC61B Sec61 beta subunit
SEC61G Sec61 gamma subunit
SEC62 SEC62 homolog (S. cerevisiae)
SEC63 SEC63 homolog (S. cerevisiae)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEPHS2 selenophosphate synthetase 2
SERINC3 serine incorporator 3
SERP1 stress-associated endoplasmic reticulum protein 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SFN stratifin
SFRP4 secreted frizzled-related protein 4
SFTPB surfactant protein B
SGK1 serum/glucocorticoid regulated kinase 1
SH3BGR SH3 domain binding glutamate-rich protein
SH3YL1 SH3 and SYLF domain containing 1
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIK1 salt-inducible kinase 1
SLC16A4 solute carrier family 16, member 4
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC35B1 solute carrier family 35, member B1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLPI secretory leukocyte peptidase inhibitor
SNAP23 synaptosomal-associated protein, 23kDa
SNN stannin
SOAT1 sterol O-acyltransferase 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae)
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SRGN serglycin
SRP19 signal recognition particle 19kDa
SRP54 signal recognition particle 54kDa
SRPR signal recognition particle receptor (docking protein)
SRPRB signal recognition particle receptor, B subunit
SSR1 signal sequence receptor, alpha
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
SSR4 signal sequence receptor, delta
STATH statherin
STIP1 stress-induced phosphoprotein 1
STK3 serine/threonine kinase 3
STOM stomatin
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
STX1A syntaxin 1A (brain)
STXBP1 syntaxin binding protein 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SYNE1 spectrin repeat containing, nuclear envelope 1
TALDO1 transaldolase 1
TARS threonyl-tRNA synthetase
TBPL1 TBP-like 1
TCTA T-cell leukemia translocation altered
TES testin LIM domain protein
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBI transforming growth factor, beta-induced, 68kDa
TGM2 transglutaminase 2
THBS2 thrombospondin 2
TIMP3 TIMP metallopeptidase inhibitor 3
TM9SF2 transmembrane 9 superfamily member 2
TM9SF3 transmembrane 9 superfamily member 3
TMED2 transmembrane emp24 domain trafficking protein 2
TMED7 transmembrane emp24 protein transport domain containing 7
TMEM214 transmembrane protein 214
TMEM39A transmembrane protein 39A
TMEM41B transmembrane protein 41B
TMEM45A transmembrane protein 45A
TMEM97 transmembrane protein 97
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNNC1 troponin C type 1 (slow)
TNNT1 troponin T type 1 (skeletal, slow)
TOB1 transducer of ERBB2, 1
TPD52 tumor protein D52
TPD52L1 tumor protein D52-like 1
TPD52L2 tumor protein D52-like 2
TRAK2 trafficking protein, kinesin binding 2
TRAM1 translocation associated membrane protein 1
TSC22D3 TSC22 domain family, member 3
TSPAN13 tetraspanin 13
TSPAN31 tetraspanin 31
TSPAN4 tetraspanin 4
TSPYL2 TSPY-like 2
TSPYL5 TSPY-like 5
TTN titin
TUBA1A tubulin, alpha 1a
TUFT1 tuftelin 1
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
TXNDC15 thioredoxin domain containing 15
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBE2B ubiquitin-conjugating enzyme E2B
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UFM1 ubiquitin-fold modifier 1
UGDH UDP-glucose 6-dehydrogenase
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
USO1 USO1 vesicle transport factor
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VAMP7 vesicle-associated membrane protein 7
VAT1 vesicle amine transport 1
VCAM1 vascular cell adhesion molecule 1
VIM vimentin
WARS tryptophanyl-tRNA synthetase
WDR47 WD repeat domain 47
WDTC1 WD and tetratricopeptide repeats 1
WFS1 Wolfram syndrome 1 (wolframin)
WIF1 WNT inhibitory factor 1
WIPI1 WD repeat domain, phosphoinositide interacting 1
XBP1 X-box binding protein 1
XPOT exportin, tRNA
YPEL5 yippee-like 5 (Drosophila)
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADCK2 aarF domain containing kinase 2
ADORA2B adenosine A2b receptor
AHNAK AHNAK nucleoprotein
AK4 adenylate kinase 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALB albumin
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANKRD10 ankyrin repeat domain 10
ANXA10 annexin A10
AREG amphiregulin
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARMCX2 armadillo repeat containing, X-linked 2
ATF5 activating transcription factor 5
ATP10B ATPase, class V, type 10B
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BEX1 brain expressed, X-linked 1
BIRC3 baculoviral IAP repeat containing 3
BMP4 bone morphogenetic protein 4
C2CD2 C2 calcium-dependent domain containing 2
C2CD5 C2 calcium-dependent domain containing 5
C3ORF14 chromosome 3 open reading frame 14
C8ORF4 chromosome 8 open reading frame 4
C9ORF16 chromosome 9 open reading frame 16
CA12 carbonic anhydrase XII
CAPRIN1 cell cycle associated protein 1
CARD10 caspase recruitment domain family, member 10
CAV1 caveolin 1, caveolae protein, 22kDa
CCBL2 cysteine conjugate-beta lyase 2
CCDC85B coiled-coil domain containing 85B
CCL20 chemokine (C-C motif) ligand 20
CCND1 cyclin D1
CCND2 cyclin D2
CD200 CD200 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CD8A CD8a molecule
CD9 CD9 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CELF2 CUGBP, Elav-like family member 2
CFI complement factor I
CHERP calcium homeostasis endoplasmic reticulum protein
CLC Charcot-Leyden crystal galectin
COL1A2 collagen, type I, alpha 2
CPA3 carboxypeptidase A3 (mast cell)
CPE carboxypeptidase E
CPT1A carnitine palmitoyltransferase 1A (liver)
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CST7 cystatin F (leukocystatin)
CTSO cathepsin O
CTSW cathepsin W
CXADR coxsackie virus and adenovirus receptor
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCX doublecortin
DENND2D DENN/MADD domain containing 2D
DPH2 DPH2 homolog (S. cerevisiae)
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
E2F5 E2F transcription factor 5, p130-binding
EFNB2 ephrin-B2
EGR3 early growth response 3
EHD3 EH-domain containing 3
EIF4A1 eukaryotic translation initiation factor 4A1
EIF5 eukaryotic translation initiation factor 5
ELOVL2 ELOVL fatty acid elongase 2
EMG1 EMG1 N1-specific pseudouridine methyltransferase
EMP2 epithelial membrane protein 2
ENAH enabled homolog (Drosophila)
EPHA2 EPH receptor A2
EPS8 epidermal growth factor receptor pathway substrate 8
ERAP2 endoplasmic reticulum aminopeptidase 2
EREG epiregulin
ESR1 estrogen receptor 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP1 fatty acid binding protein 1, liver
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM57A family with sequence similarity 57, member A
FANCL Fanconi anemia, complementation group L
FASN fatty acid synthase
FERMT1 fermitin family member 1
FGF13 fibroblast growth factor 13
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
FPGS folylpolyglutamate synthase
FRZB frizzled-related protein
FST follistatin
GAL galanin/GMAP prepropeptide
GATA2 GATA binding protein 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GPM6A glycoprotein M6A
GPM6B glycoprotein M6B
GPR171 G protein-coupled receptor 171
GPX2 glutathione peroxidase 2
GREM1 gremlin 1, DAN family BMP antagonist
GSTM3 glutathione S-transferase mu 3 (brain)
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAL histidine ammonia-lyase
HAS2 hyaluronan synthase 2
HBB hemoglobin, beta
HES1 hes family bHLH transcription factor 1
HIST1H4C histone cluster 1, H4c
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HOMER1 homer scaffolding protein 1
HOXC6 homeobox C6
HSPG2 heparan sulfate proteoglycan 2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IER3 immediate early response 3
IFITM1 interferon induced transmembrane protein 1
IL13RA2 interleukin 13 receptor, alpha 2
IL1R2 interleukin 1 receptor, type II
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
INPP1 inositol polyphosphate-1-phosphatase
ITGA6 integrin, alpha 6
ITGB5 integrin, beta 5
JADE2 jade family PHD finger 2
JAG1 jagged 1
JAM2 junctional adhesion molecule 2
JUNB jun B proto-oncogene
KANK1 KN motif and ankyrin repeat domains 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KEAP1 kelch-like ECH-associated protein 1
KLF4 Kruppel-like factor 4 (gut)
KLHL23 kelch-like family member 23
KLK10 kallikrein-related peptidase 10
KLK11 kallikrein-related peptidase 11
KLK7 kallikrein-related peptidase 7
KPNB1 karyopherin (importin) beta 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT17 keratin 17, type I
LAMA4 laminin, alpha 4
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAPTM4B lysosomal protein transmembrane 4 beta
LBP lipopolysaccharide binding protein
LDLR low density lipoprotein receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LMNA lamin A/C
LOC100505650 uncharacterized LOC100505650
LPL lipoprotein lipase
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGEA3 melanoma antigen family A3
MAN1A1 mannosidase, alpha, class 1A, member 1
MARCKSL1 MARCKS-like 1
MECOM MDS1 and EVI1 complex locus
MET MET proto-oncogene, receptor tyrosine kinase
METTL7A methyltransferase like 7A
MFAP2 microfibrillar-associated protein 2
MGLL monoglyceride lipase
MGP matrix Gla protein
MMD monocyte to macrophage differentiation-associated
MMP12 matrix metallopeptidase 12
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MREG melanoregulin
MRPL15 mitochondrial ribosomal protein L15
MSRA methionine sulfoxide reductase A
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MTA1 metastasis associated 1
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO5C myosin VC
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAV3 neuron navigator 3
NCAM1 neural cell adhesion molecule 1
NDN necdin, melanoma antigen (MAGE) family member
NFIB nuclear factor I/B
NGRN neugrin, neurite outgrowth associated
NID1 nidogen 1
NMU neuromedin U
NOP16 NOP16 nucleolar protein
NOP56 NOP56 ribonucleoprotein
NREP neuronal regeneration related protein
NRN1 neuritin 1
NT5E 5'-nucleotidase, ecto (CD73)
NUP85 nucleoporin 85kDa
NXT1 nuclear transport factor 2-like export factor 1
OPN3 opsin 3
OSBPL10 oxysterol binding protein-like 10
PEA15 phosphoprotein enriched in astrocytes 15
PEG10 paternally expressed 10
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIP prolactin-induced protein
PLAGL1 pleiomorphic adenoma gene-like 1
PLAT plasminogen activator, tissue
PLBD1 phospholipase B domain containing 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PODXL podocalyxin-like
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PON2 paraoxonase 2
PPARG peroxisome proliferator-activated receptor gamma
PPIF peptidylprolyl isomerase F
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCB protein kinase C, beta
PROM1 prominin 1
PRSS21 protease, serine, 21 (testisin)
PRSS3 protease, serine, 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PWP1 PWP1 homolog (S. cerevisiae)
PXDN peroxidasin
RBMS1 RNA binding motif, single stranded interacting protein 1
RBP1 retinol binding protein 1, cellular
RCN1 reticulocalbin 1, EF-hand calcium binding domain
REC8 REC8 meiotic recombination protein
REEP1 receptor accessory protein 1
RELN reelin
RGS5 regulator of G-protein signaling 5
RND3 Rho family GTPase 3
RPS11 ribosomal protein S11
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RTP4 receptor (chemosensory) transporter protein 4
RUNX3 runt-related transcription factor 3
S100A12 S100 calcium binding protein A12
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SATB2 SATB homeobox 2
SCARB2 scavenger receptor class B, member 2
SCG2 secretogranin II
SCGB2A2 secretoglobin, family 2A, member 2
SCO2 SCO2 cytochrome c oxidase assembly protein
SEPP1 selenoprotein P, plasma, 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFRP1 secreted frizzled-related protein 1
SGCE sarcoglycan, epsilon
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC35F2 solute carrier family 35, member F2
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SMAD1 SMAD family member 1
SMAD3 SMAD family member 3
SMAGP small cell adhesion glycoprotein
SMYD2 SET and MYND domain containing 2
SNAI2 snail family zinc finger 2
SOX11 SRY (sex determining region Y)-box 11
SOX4 SRY (sex determining region Y)-box 4
SPINK1 serine peptidase inhibitor, Kazal type 1
SPON2 spondin 2, extracellular matrix protein
SPRR1A small proline-rich protein 1A
SPRY2 sprouty homolog 2 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SRPX sushi-repeat containing protein, X-linked
STMN1 stathmin 1
SULF1 sulfatase 1
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TAGLN2 transgelin 2
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TDO2 tryptophan 2,3-dioxygenase
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TFPI2 tissue factor pathway inhibitor 2
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBD thrombomodulin
THY1 Thy-1 cell surface antigen
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TKT transketolase
TKTL1 transketolase-like 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM5 transmembrane protein 5
TNC tenascin C
TOR1A torsin family 1, member A (torsin A)
TOX3 TOX high mobility group box family member 3
TP53I3 tumor protein p53 inducible protein 3
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRIB2 tribbles pseudokinase 2
TSC22D2 TSC22 domain family, member 2
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSPAN12 tetraspanin 12
TSPAN8 tetraspanin 8
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TXNDC9 thioredoxin domain containing 9
TYRP1 tyrosinase-related protein 1
UBE2E3 ubiquitin-conjugating enzyme E2E 3
USP1 ubiquitin specific peptidase 1
VCL vinculin
VSNL1 visinin-like 1
VTCN1 V-set domain containing T cell activation inhibitor 1
VWF von Willebrand factor
WASF1 WAS protein family, member 1
WFDC1 WAP four-disulfide core domain 1
XIST X inactive specific transcript (non-protein coding)
ZBTB20 zinc finger and BTB domain containing 20
ZEB2 zinc finger E-box binding homeobox 2
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF91 zinc finger protein 91
Funding